ZMP
dvl2
Ensembl ID:
ZFIN ID:
Description:
segment polarity protein dishevelled homolog DVL-2 [Source:RefSeq peptide;Acc:NP_997813]
Human Orthologue:
DVL2
Human Description:
dishevelled, dsh homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:3086]
Mouse Orthologue:
Dvl2
Mouse Description:
dishevelled 2, dsh homolog (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:106613]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa40866 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa20904 | Essential Splice Site | Available for shipment | Available now |
| sa6076 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa40866
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000012450 | Nonsense | 232 | 747 | 6 | 15 |
| ENSDART00000135316 | Nonsense | 179 | 694 | 5 | 14 |
Genomic Location (Zv9):
Chromosome 7 (position 21438602)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 20029038 |
| GRCz11 | 7 | 20281006 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGCATCTAGATTGCTCAAACGCCACCGAAGACGCCGGAAACAGCGGCCA[C/T]GACTGGAGAGGGTGAGATACACCTATGTGATTAACAAATGTCAAGTCTAT
Long Flanking Sequence:
AGAAATTTTAATATGATTCGTGATCTTGCTTGAAGAAGACAGAGATCAGTTATCAAGATTAAAAGATCCAGGATCTGCCAAAACATCTTTGATCATTTAAATGAGGTACGAAGAGCAGACCCCTGGTTTTGTCATTATAGCTAGAGAAGCTGATTTGGCAATAAATTCAGAACTCCCACTCTCAGTTAGATATGCATTATTACAATAGTGAAGAAAAAAATAGACACTTATTTGTAAGAAGATAAACATGCAATAGACAAACAAATATTTAGCTAGCCAATCGGTTTAATTTGTTGGATGCTGCTTTGCCACTTGGTGTGTATTATAATAGAGTCTGGATCCTGAACCAAAAGCCATTGAGAATCTAGTGTTTTAGGTTGTGCATTAATTCTGAATGTTTATTGTGCTAAATGTTTGTGATCAGGTTCAGCAGCTCCACTGAACAGAGCACAGCATCTAGATTGCTCAAACGCCACCGAAGACGCCGGAAACAGCGGCCA[C/T]GACTGGAGAGGGTGAGATACACCTATGTGATTAACAAATGTCAAGTCTATCATTTTCCCATCCTCCGTTTGTTACAAACCTGTTTGTAGAAAATATACTGAGAAATGTTGGTAAAAACAGCCTTTGACTTCCAGATTACTTTTGGTTTCTCCTATGGATGACTGTGTCTACTATTTTCAGTATTTTTCAAAATATCTTATTTTGTACAGAAGCAAGCAGGGTTCCCACGCTACTTGAAAGTACTTTTTAGAATGAATTTTAGACATGTGAAAGTGCTTGAAGTAAATTTGTATTAAAATTGATTTATGGTTTTATTTCAACAGTTATACTCAATTTTCAAATAAATTCATAAATTATTATTTTTTTAAATAATTTTTTTTTTACAATAACACTGACAAATAATGAACTTTTTTAATATTATAAATAAAATGATTACCAGTATTGAATTAAACAAATTGTATTAAATTTTGTTGGAACATGACCATTTATAAAAGTCAGAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20904
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000012450 | Essential Splice Site | 498 | 747 | 13 | 15 |
| ENSDART00000135316 | Essential Splice Site | 445 | 694 | 12 | 14 |
Genomic Location (Zv9):
Chromosome 7 (position 21446109)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 20036545 |
| GRCz11 | 7 | 20288513 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTGAACAGTGCTACTACATATTTGGAGACTTCAGCAACTGTGAAAACTG[T/A]ACGTAGAATCAGCTTATCTGACAGTAATATCAATGAGCAGTAATTTTCTG
Long Flanking Sequence:
CACCGAAACCGAACGTAAATATTGTGCTTATTTAGTCTGCTTCTCCACCTCCTAGTCCCATCACTAATCCTCTGTTTCTGTCCGTAGGCTTTGATGAGTTTAACCTGTCTCTTCGCTCAGACATGGCCTCGGTCGCTAAAGCCATGGCATCTCCAGAGTCCGGTCTAGAAGTCAGAGATCGAATGTGGCTGAAGATCACCATTCCCAATGCTTTTCTGGGTCAGAGACCTGTGCAATTATTATTATTGATGAGTATGTAACTGACGAGCGTTTATTCTGATCTCATGTATGTTTATCTGTGGTTTTCTGATTGTGGATGCAGGTTCAGATGTGGTGGAGTGGTTGTACCATCACATTGATGGCTTTCAGGACAGACGCGAAGCTCGGAAATATGCCAGTAACTTACTAAAGGCTGGTTTCATCAGGCACACTGTCAACAAGATCACCTTCTCTGAACAGTGCTACTACATATTTGGAGACTTCAGCAACTGTGAAAACTG[T/A]ACGTAGAATCAGCTTATCTGACAGTAATATCAATGAGCAGTAATTTTCTGACAAATGATCTTCATTACAGAAGTTATGTTTTCTGTTTTATTATATAGTGTAATGTCATTTATTTTAACGATGCAAAGCTCATTTTTCAGCATCATTATTCCAGTCTCCATTGTTTATTTGGCTGGTTTGCTGCTCTGTTACGATCAGTTGTTGTTGTTGTTATTATTAGTACTACTACTATTACTAGTATTACTACTACTATTACTAGTAGTAGTAGTGGTAGTCTTCATCGTCGTAGTAGTCTGCAGTGGCGGCATAGTCAATAGTATTTTTGTTTCTACTTTTCATAATTGCTTGATCGTTGTCATTATTATAAGTATTAGTATTAGTAGGCATCGTCAAAGTCAGAAGTATTTAGTCTGCTTTTTATTATTGCTTATTGCTTAGTAGTAGTCGTCATCCTCAGTATTATTTATAGTCTACTTTTCATAATTGCTTATTGCTCATTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa6076
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000012450 | Nonsense | 730 | 747 | 15 | 15 |
| ENSDART00000135316 | Nonsense | 677 | 694 | 14 | 14 |
Genomic Location (Zv9):
Chromosome 7 (position 21450724)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 20041160 |
| GRCz11 | 7 | 20293128 |
KASP Assay ID:
554-3950.1 (used for ordering genotyping assays)
KASP Sequence:
CCCCGACCCGAGACCTGGGCTCCGTCCCGCCTGAGCTGACTGCTTCCAGG[C/T]AGTCCTTCCACCTGGCCATGGGCAACCCCAGTGAGTTTTTTGTGGATGTG
Long Flanking Sequence:
CTGTTTTGCTTCCGTGTTTCTCAGGGAGTCACAGTAGTGGCTCCACACGCAGCGATGGAGAAAAGAGAAGGGGCCCTAAAAGCGTTTCTGAGAGTACTGTGGGCGGCAGCGTGCGTGATGATAAATCTCCTGGCGGGGGCGGAGCTGACTCACGTTCTGGCAGCGGCAGCGAATCAGATTACTCTGTTCGCAGCACCCTGAGACGAGATCATGGCTCAGCCACACCCAGCGAACACAGCCGCTCGAGTCAGCGCTCGCATCACCGCGTCCCGCCCCCTCACCTCGCCCCGTATCCGCCCGGCATCCCCATCCCATACAACCCAATGATGGTGATGATGGTGCCCCAACACCCACATCTGGCGCTTGGAGCACCACATCCGCAAACACCTACTCTGCCGCCCCACCCTGGCTTACCCCCAACCGGCATCCCCGGCGGGCCTCCAGGAGCTCCCCCGACCCGAGACCTGGGCTCCGTCCCGCCTGAGCTGACTGCTTCCAGG[C/T]AGTCCTTCCACCTGGCCATGGGCAACCCCAGTGAGTTTTTTGTGGATGTGATGTAATGAAGGATGTACCCGAGTGAAGGATGGAGGTTTGTAATCACGTGATAACTGTGAGTTCTGCTCTGCGACGGACAGAGATGTAGTTTACTGTATCAGTGCAGCTCTTTAGAGTTAGTGTTTGTCCTTGACGGTAGGAACAGGGTTTACGGAAGGGTAGGAAGTCTTGCATAGCACAGACTTCAAAATGCATTTGGTTTTTGTGGTATTAACCGCAACAGGGTCTGGCCTTCTAAATAACTCTTCTGCTAAAAAAAATACTAAAGAAAGAAAGAAAAAAAGCCTTGTTTTCTGAGTCCTGTTATTTTCTTTAAATGTTTCCACAAATGGCTGGAAGGCCTTCGATTAAGATCTACAAAGGCTTCTCATGACTTGCCAGAAAATATTGCTCAAAGGAAGTTCAAGTAAGCTTTACACACCTTTTATAAAGACCAACATTAGGACACG
Associated Phenotype:
Not determined