Busch Lab

ZMP

insra

Ensembl ID:
ENSDARG00000011948
ZFIN ID:
ZDB-GENE-020503-3
Description:
insulin receptor a [Source:RefSeq peptide;Acc:NP_001136144]
Human Orthologue:
INSR
Human Description:
insulin receptor [Source:HGNC Symbol;Acc:6091]
Mouse Orthologue:
Insr
Mouse Description:
insulin receptor Gene [Source:MGI Symbol;Acc:MGI:96575]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa6016 Nonsense Mutation detected in F1 DNA Not yet available
sa1682 Essential Splice Site Available for shipment Available now
sa32968 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa6016
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008302 Nonsense 687 1353 10 21

The following transcripts of ENSDARG00000011948 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 37284943)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 37581653
GRCz11 2 37564110
KASP Assay ID:
554-3752.1 (used for ordering genotyping assays)
KASP Sequence:
GAGCCCCCACACAAGTGGACAACGAAGAGGAGCAGAAGTGGAACCAAACT[G/T]AGGAGCAGGGCCCTGATAGCCGCTGCTGCGCTTGTCCTAAAACAGAGAAA
Long Flanking Sequence:
CCTAAACCTAGCTCTGTTGTAGGAGTTGAGAATGAAATTGTTTACTACATAAACATAATTACATGATAAAAAGAACAACGTAAAATTAAGTTAACTCTTTGTTTTGAACTCGCTCATGTTCTTTTCTTGTACTTTTTTTTTCTTTCATTCTTTTTATTTTAGAGCCATCAGTGCCTCTGGACCCCATATCCTCGTCAAACTCCTCATCCCAGATCATTCTAAAATGGAAGCCACCAAACGATCCTAATGGAAACATCACTCATTACCTGGTCTTTTGCCAGCAACAGCCAGAGGCCAGCGAGCTCTACAAATTTGATTACTGCCAGAAAGGTTCGAAAACATACAGGAACATAATAACAATGCACACTTCCATTGATAGGTCTGGAGTTTGTAAGGTAATCTGTTGAGATCCTGTATGTTTCTGTTGATCAGGTATGAAGCTGCCCACCAGAGCCCCCACACAAGTGGACAACGAAGAGGAGCAGAAGTGGAACCAAACT[G/T]AGGAGCAGGGCCCTGATAGCCGCTGCTGCGCTTGTCCTAAAACAGAGAAACAACTGAAGAAAGAGGCGGAAGAGACGGAGTATCGAAAAACCTTTGAGAACTACCTCCATAATGAAGTGTTTGAGCTCAGGTAAATCTTCTTTCAGCTGTTGTGGAAAAAACTGTAACAGTATAATCAGTGATGAAAATTATTTAACCAATTAGATGATCCACCCAAACTATAAACTTCTCTGTGAATAACAGTACATTTAGCTATTTTTGGTTCCGATCTATGTAGTATGATATTAATCTTGTCATATATAAATAATATACCTTATGCATTACAGCTCTTTTACATGAATAGACAATCTGTATGTATGTATAACCTAGATCATGTAGACATGTTTATTCATAACATACTTTTTTGAAGACATTATATAAAGTTTTTTCTAAATTAAATGTGAATTGCATAAACATTAATGCATATACAGTAATAGAATGCATTGTTATTATATGAATGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1682
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008302 Essential Splice Site 824 1353 11 21

The following transcripts of ENSDARG00000011948 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 37279993)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 37576703
GRCz11 2 37559160
KASP Assay ID:
554-1628.1 (used for ordering genotyping assays)
KASP Sequence:
GACTCGATGCAGTATGGCAGCCTACGTCAGTGCCCGCACCATGCCTGAAG[G/A]TAGAGGATTTTTATTTATGATGCAGTGTTATTGTTTAGAATGTAGCTATT
Long Flanking Sequence:
GGGTAGTCAATTTGATCAATAGACAAGGGTAAACATGGAAATGATATTCATCTTTTAAATAGTCTTGGTTGTTGTAACAAGATGCACTTTAACATGGTTGGCTGATTTTTATAGTAAAATTGAGTAAAATTATTTAATTAAAGCAATAAATAGCAATAGAATCCTTATAAGATTGGACTTAAATCTTGACCCTCTTGTGTGTTTCTGTGTATGCAGGCCATCAAGACAGCGCAGATCTCTGGTGGGCATTGCTAATAGGACGTCCTCTCGTCTTTTCACCACACCCTCCTCACTCCCCAATGGCTCTGCTACTCGTAGCCCAGAAGAGGAAGCAGAGGCCAACAAGATTTCACTGATTGTTCAGGCCAAGGAGTCAACAGTCATCTCCAATCTACGGCATTTCACCAGCTACCAGATAGAAATCCATGCATGCAACCATGGCAGTGACCCGACTCGATGCAGTATGGCAGCCTACGTCAGTGCCCGCACCATGCCTGAAG[G/A]TAGAGGATTTTTATTTATGATGCAGTGTTATTGTTTAGAATGTAGCTATTATTATTATTATTATTATTAGGTCTTTGTACAATTTAAAAAAAACATCTTGTATGTTTAAGAACTCAAAACTTCTTAGTCTAAAAACAGCTTCTAAGGTATTTTGCTAAAACAACAAGTTGATAAAATGTCCCTTTATCATATAATAGTCTGCCTAAACCCCGCCTTTTAGGAAGTAGATCAACACCTGCTTCTACTGCATCACTGCTTGTTTAGCTCCGCCCAGAGATCCATGCTGTTGTATGTAAACATGGACACGGAAACCAATGATTAAACGGCTATGAAGACGAAATCTGTAAAGTGTCAACTTGTGGAATAACAATGTGTTTATATTATGGCATCCTGCTAATCCCAGCATTAGGAAGCGTGGATGAGTTTTATTTATTTATTTATTTATTTTTAAACTTCCCGACCATGTAGGTAAGATCTTGGTCCGTTGTTCACCTCATTTT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa32968
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008302 Nonsense 1153 1353 19 21

The following transcripts of ENSDARG00000011948 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 37269015)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 37565725
GRCz11 2 37548182
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATTTAATTTCTGTTGATTTTATCTTGTGTACTCAGATTTTGGCATGACC[A/T]GAGATATTTATGAGACGGATTACTACAGAAAGGGTGGGAAGGGTCTTCTT
Long Flanking Sequence:
TTTTGCATTTTTAATTTTTATAGCTTTGAATAATTTAAAAAGAGCCACATATTGATAAATAATGTTATAACAGCTGTCTAAATATTAAGTTAAGATTGAATTGCCTCTTTTTACAGTTATGAAATAGTTTGATAACAAGCAGGAAATGTTCATGGGCCAATGACATGACCGCATTGAAATGGTCTATAGACATCTAAGGATAGCCCAAATCTAGACTAGTGGTCAAATAGACAGAATAGACAGACTTTATATGTGTAGTCATTCATTTCTTTTTATTTGATGACTAGTCTAATTTTGATCTATTCCTAGACGTCTATTAGATTTTCACTGACAGCCCAAATTTAGCCTTGTTTTAGCCAAGACAACCATGTTTAGACATCTATTAGTCTTGCTGGGAAAATACCTGTAATTGAATTATAATATATGTAATTATAATTAAATATGTGATTTAATTTAATTTCTGTTGATTTTATCTTGTGTACTCAGATTTTGGCATGACC[A/T]GAGATATTTATGAGACGGATTACTACAGAAAGGGTGGGAAGGGTCTTCTTCCAGTGAGATGGATGGCACCAGAGTCGCTGAAGGATGGTGTTTTCACAGCTCACTCAGACTGCTGGTGAGCTGACTGTCTATACGCACACAGCCTTACTAATACATCAGTAATTGTTGTTGCTCGTGTGTTTAGTCTTTCATGACCCATCTTGTGTTTGTTTAGGTCGTTTGGTGTGGTGTTATGGGAAGTCAGCACTCTGGCTGAACAGCCGTATCAAGGCCTGTCCAATGAACAGGTCCTTAAATTTGTGATGGAAGGAGGATATCTGGACAGACCAGACAACTGCGCAGACAGATTGTGAGTGTGTTGCTGACATGCTGTAACATGTCAGTGTTTGGTGCAAGGATACTGTATCTGACTTCAAAAAGGGTGGTTCTGTTTTGTTTCTGGCTAATGGGATTCATTTAGCAGATGTTTAATTAATTGTAGCCAGAGTGGATTCTATTTG
Associated Phenotype:
Not determined