ZMP

cfl1l

Ensembl ID:

ENSDARG00000012972

ZFIN ID:

ZDB-GENE-040426-2770

Description:

non-muscle cofilin 1 [Source:RefSeq peptide;Acc:NP_998804]

Human Orthologues:

CFL1, CFL2, DSTN

Human Descriptions:

cofilin 1 (non-muscle) [Source:HGNC Symbol;Acc:1874]
cofilin 2 (muscle) [Source:HGNC Symbol;Acc:1875]
destrin (actin depolymerizing factor) [Source:HGNC Symbol;Acc:15750]

Mouse Orthologues:

Cfl1, Cfl2, Dstn, Gm6180

Mouse Descriptions:

cofilin 1, non-muscle Gene [Source:MGI Symbol;Acc:MGI:101757]
cofilin 2, muscle Gene [Source:MGI Symbol;Acc:MGI:101763]
destrin Gene [Source:MGI Symbol;Acc:MGI:1929270]
predicted pseudogene 6180 Pseudogene [Source:MGI Symbol;Acc:MGI:3643972]

Alleles

There is 1 allele of this gene:

Allele Name	Consequence	Status	Availability
sa5863	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa5863

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000026464	Essential Splice Site	1	163	1	4

Genomic Location (Zv9):

Chromosome 13 (position 33831518)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	33497498
GRCz11	13	33607043

KASP Assay ID:

554-3944.1 (used for ordering genotyping assays)

KASP Sequence:

GGGCAACGACACACTNNTCTCTCTCTTCTCCAAACAAGCGACAGACATGG[T/A]AAGTGCTCAGATTTTGGTGTACGTTTTGTGGACTGTACTRTAGTGTCCAA

Long Flanking Sequence:

AATGAAGTTGCTGGTCTGTCGCTAAACATGAAACCACGTCACGCTCCGTGCATTTTTTACACCTGGATCCTCCCATCCGCGCAAATTTAGTATTTGAGCTCCTCTCACCAAATACGGGTTTTTGTCAGGCTTTCTATGCGTTTCTGTCTTCCTTATAAGGTCGTTTTGTTCAGTCTCCGCCTCCAAATCTGCGTCTGACTCACCTGAGCCATTTCACGTGCCATAAGCGCATAATTTTTATAACACCTTTTTTTATCACAAGCACAAAATATAAATAATTTTGCGGCAACGGGATATATTCCTACACAACCATCCAGTATTTAAAGTCGTTTGCAGTCGCGGACAGGCACAGCAGGTGGAAAGTCAGGTCGTTCAGGACTGATCTGTTTTGAGGAGGAGGAGGGAGTGTTCACATCCGCGCGCTGCTCGGAGTCGCTTTCTTGCAGTTCAGGGCAACGACACACTTCTCTCTCTCTTCTCCAAACAAGCGACAGACATGG[T/A]AAGTGCTCAGATTTTGGTGTACGTTTTGTGGACTGTACTATAGTGTCCAAATATGCTAATCAAGTGAAGGTAATTTGCATTAAAACGGTTTAGCGCCGTGCAGAGTAGCGTATGTTAAAAAAGCTATTACGCCAATTCATCCATGAGAGGCTTGTGGCTTCCTGTTCATTGGTAAACTTCTTTTATTTATTTAAATCCCTAATACTTTATATAAAAGGTTAAAACTAGCTTGTCAGTTTAAAATATAAAGCAATTAAAGTAATAAAAGCTCATTGACTTTGGTGAGACTTGGTGGAAAAGCCATATTTTAAGGTTTCTTATTTGTGTAATACTTTTCTAGATAATTGTTTGGACAGGACAGAATGTGTTGAGCCACACCTTACATCAGACATGTTCTCATGTCAAAAGCTCTGAGTAATGCTAATGAACTGCTGGTAGCTATAGTGTGTTAATACTTTTGAACTAGAGTAGCTCATTGCTTGTGTCAGAGTTGTATTCCA

Associated Phenotype:

Not determined