ZMP
bmpr2b
Ensembl ID:
ZFIN ID:
Description:
bone morphogenetic protein receptor type-2 [Source:RefSeq peptide;Acc:NP_001034896]
Human Orthologue:
BMPR2
Human Description:
bone morphogenetic protein receptor, type II (serine/threonine kinase) [Source:HGNC Symbol;Acc:1078]
Mouse Orthologue:
Bmpr2
Mouse Description:
bone morphogenic protein receptor, type II (serine/threonine kinase) Gene [Source:MGI Symbol;Acc:MGI
Alleles
There are 5 alleles of this gene:
Allele Name | Consequence | Status | Availability |
---|---|---|---|
sa41374 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
sa34578 | Nonsense | Mutation detected in F1 DNA | Not yet available |
sa41375 | Nonsense | Mutation detected in F1 DNA | Not yet available |
sa5781 | Nonsense | F2 line generated | Not yet available |
sa2507 | Nonsense | F2 line generated | Not yet available |
Mutation Details
Allele Name:
sa41374
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000002334 | Essential Splice Site | 147 | 1071 | 3 | 13 |
ENSDART00000125961 | Essential Splice Site | 147 | 1071 | 3 | 13 |
The following transcripts of ENSDARG00000020057 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 9 (position 13310152)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 9 | 13062717 |
GRCz11 | 9 | 13033920 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGTCAACTTCACAGAGAACTGGGTGCCCAGTCCCACCAGCACTGCCAACC[G/A]TAAGTCCTACAAACGCAGCATCTCTAGACTTCATCTGAAAGCCCCATGTC
Long Flanking Sequence:
AATATAATATAATATAATATAATGCAAAATAATTAATATAATATAATATAATATAATATAATGCAAAATAATTAATATAATATAATAAAATATAATATAATATAATATAATGCAAAATAATTAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATAAAATATAATATAATATAATATAATATAATATAATATAATATAATATAATCATCTCTACTCATTGTTAAGAAACTCCAGTTTGTATCTCAGTGTTTCACTCCACCATCTGCATCTTTTCATCGCAGGCTGTTGGACTTACATTGGTGACCAGCAGGACTGCCATGACGACCGTTGCGTGGTTACCACAACGCCATCGCAGATCCAGAATGGCACCTACAGATTCTGCTGCTGCAGCACCAACATGTGCAACGTCAACTTCACAGAGAACTGGGTGCCCAGTCCCACCAGCACTGCCAACC[G/A]TAAGTCCTACAAACGCAGCATCTCTAGACTTCATCTGAAAGCCCCATGTCCCTGTCTGAGAGTCAACGCCCGTATTAGATTTCTGTGACGGAGGAAAACTGGTCTTGCAGGATCCATTGTCAACAATCTCAGCACAAATCAAGCTCTGTAATGTTCTTGTATCAGCATGTTGTGATGTCATTCGTTTACACATTTTAGGTTTACCAAAATTTATTAATATAAAATGTACTCACTCTCATGTTATACTAGATGCAGGTGTAGATGTTTATTTTTTCTTCAGTTAAACAAAAAAGAGCCCACAAAGCACTTTTATGTTTAAAAGACTTCTAATAGACGTCTAAACATAGACGTCTTTAATTTGGTCTGTCAGCGAAGATCTAATAGACGTCTAAGAAAAGCCTAAATGGAGACTAGTCAGCAAACAGACAGGAAAGAATGACTACACATGTGAAGTCTGTCCAATCCCAGCAGGCAGACGTCATAAGATATTAATGTTAGGT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34578
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000002334 | Nonsense | 516 | 1071 | 11 | 13 |
ENSDART00000125961 | Nonsense | 516 | 1071 | 11 | 13 |
The following transcripts of ENSDARG00000020057 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 9 (position 13381491)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 9 | 13134056 |
GRCz11 | 9 | 13105259 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTGACAGCGCAGTGTGCAGAGGAGCGTATGGCAGAACTGCTGCTGATTT[G/A]GGAAAGGAACAAACCTGTCAGTCCCACCATCAATCCCATGAGCACAGCGC
Long Flanking Sequence:
TTAAAAATCCCATGGCACTTCTCGTAATTAGTAGGGGTGTAACCCTGGTGTCCTGGCCAAATTCCCTCTCTGCCCTTGCCCATCATGGCCTCCTCAATCATCCCCATCCACTGAATTGGCTCTATCACTGTCTCTCCACTCCCTCTATAGCTGGTGTGTGGTGAGCGCACTGGCGCTGTTGTCCTGTGGCTGCCGTCGCATCATCCAAGTGGATGCTACACACTGGTGGTGGTGTGGAGAGATCCCCCTAATGATTGTGAATCACTTTGGGTGTATGGTCATACACATTAAATGCGCTATATAAATACACATTACATTACATCTAAAACATGCAACAGTATAATAATGACATGTCTGTTTTAACACATCGCTCTCCTCTCCTCTCTTCCAGGCTGTGCGCTCTCTAAAGGAGACTATGGAGGATTGCTGGGATCAGGATGCAGAGGCTCGTCTGACAGCGCAGTGTGCAGAGGAGCGTATGGCAGAACTGCTGCTGATTT[G/A]GGAAAGGAACAAACCTGTCAGTCCCACCATCAATCCCATGAGCACAGCGCTGCAGAACGAGAGGTCCGATCGATGCACTCACAATGTTCATTACATGAATAATAGTTCCAGATTGGGCTTTTGTATTATTAATATATATTTTATATTTTATGCCAGATATTTTAAATCACTTTTTTTTTATCAGAAACATACCAATGGGCTATATGCACAACTAGTGTTTTTCAGCCAACAATAAACTTCTGTTGAAAGCTTAATGTGACTATTTTAAATTCAATAAGGTTTCTTTTAACAGGATTGACAGCATAATGGAATTAAAATACATTCATTTAAATAAAGTTAAGCATTCATTTAGTTGTTTAAGCATGAAACAAGATGATAGACTGTGTAAACTCTAGTGCTGTCAGTGGTAGCAGGCTAACGCAGAAACTCCATTGAAAATACTGAGGTAAAATAAATAAGGCAGGGAAAAACAGAATTTAATGCAGTGCTTCTTGTCTGTC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa41375
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000002334 | Nonsense | 773 | 1071 | 12 | 13 |
ENSDART00000125961 | Nonsense | 773 | 1071 | 12 | 13 |
The following transcripts of ENSDARG00000020057 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 9 (position 13383371)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 9 | 13135936 |
GRCz11 | 9 | 13107139 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAAACAGCAGAATCTCCCCAAGAGGCCCACTAGCTTACCCCTCAACACC[A/T]AAAATCCTGGTAGGGAGTCTTCGTCGTCTCGATTGAAATTCGGGAAGCAC
Long Flanking Sequence:
ACTATGAAAGACAGCAAGCTCAGGCGCAAGCTCGACTGCCCAGTCCTGAAACCAGCGGCACAAGTTTGTCCACCACAACCACCACAACAGGCCTCACACCCAGTACCATCATGACCACCATCTCCGAATCGGGCCACTCGGAGGACACAGGAGCCGGAGGAAGTGTACCAGTGTGCCTTCAACTCACAGAGGAAGATCTGGAGACCACCAAACTGGACCCCAAAGAGGTGGACAAGAACCTGAAAGAAAGTTCTGATGAGAATCTGATGGAGCACTCGCAGAAACAGTTCAGCGCCCCTGATCCACTCAGCTCGGGCAGCACCAGTCTTTTATACCCACTGATTAAACTCGCAGCAGAAGTGACTGGAGGATCTGGAAGTGGTGGACAAACTGATTTCGGGGTGGGCAGCAGTGGAATGAGCGACACTCCCACAGCCATGTTTCCTCTCCCCAAACAGCAGAATCTCCCCAAGAGGCCCACTAGCTTACCCCTCAACACC[A/T]AAAATCCTGGTAGGGAGTCTTCGTCGTCTCGATTGAAATTCGGGAAGCACAAGTCCAACCTGAAGCAGGTGGAGACAGGTGTAGCCAAGATGAACACTGTGGTGGCCGTCGAGCCACACTTGGCCACCGTCACCAACAATGGACCCAGTGTGCGCAGTGGTGCTGGAGTGGTCGTAGTAAATGGATATGGAGTGGGCAATGGTGCCAGCTCCTCTGATGCGTTTGGAAACACGAACCCCGTCGGGCCACAGGGTGAAGGGGGCGCTCCTCTGCTGCAGAGCCAACTGAGCGGAGAAGACAGCCGACTCAACATCAACATCAACTCCAGCCCTGATGAACACGAGCCCCTGCTAAGAAGAGAGCAGCCGGCCGCGCGGGATCACTCCGGTCGCACCAACTCCAACAACAACAACAGCAACATTCACACCACTGCCACGGTTTGTGCGCTCACCGCTGCAGACGCCCAGATAGAGGCTTTAACCTGCCTGTCGGGAGCGCCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa5781
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000002334 | Nonsense | 1003 | 1071 | 13 | 13 |
ENSDART00000125961 | Nonsense | 1003 | 1071 | 13 | 13 |
ENSDART00000002334 | Nonsense | 1003 | 1071 | 13 | 13 |
ENSDART00000125961 | Nonsense | 1003 | 1071 | 13 | 13 |
The following transcripts of ENSDARG00000020057 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 9 (position 13387169)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 9 | 13139734 |
GRCz11 | 9 | 13110937 |
KASP Assay ID:
554-3063.1 (used for ordering genotyping assays)
KASP Sequence:
GCTGAGAAGATTAAAAAACGTGTGAAGACWCCTTATTCGTTGAAAAGATG[G/A]CGTCCTTCCACATGGGTCGTCTCCACTGATACACTAGAYGGAGAGGTGAA
Long Flanking Sequence:
AAATTCCACTGCATTGATAAGAATCCTGAAACCGTTCGGCCTCAGTTGGCAGCGGCGATAAAGAGCGTAATGACGCTTGTTAGCTAGAACCTGAAGCAGACACTAAACAGGAAGATAAAAAAACAAAAACAGTCAAGCTGCCCACGTGTTTACATTCTGCATGCGGACCCAAGAGGAGATCTGAACCGATCGAACCTGATGATTCAGACTCAAGCGCACGCTGAGAGAGCTAGTGTGGGAAAGGTCAACCACAAATTTGAGTGTGCTGAAATACTACTCTTTGGGCGGGTTGTTTGGAGCAGCACCGCTAGTATTCCCGATTGGCACATTGCAACACGCACAACTGTTTCTCATTGTCGTGGAAGACTGTAATTAAGGATGTTTGTTAAAATGTGACCTTCTTTTTCTGTTTTAGATGAGGCCGTGTCGCAGGAGGGAAAGGCCGGATCAGCTGAGAAGATTAAAAAACGTGTGAAGACTCCTTATTCGTTGAAAAGATG[G/A]CGTCCTTCCACATGGGTCGTCTCCACTGATACACTAGATGGAGAGGTGAACAACAACGGGCACAGCCAGCAGACGATGATGGCAGTAAGTGGAGGTGGTCACCCAAGCGCTGGCCAATCAAAGTCCAGCATCGCCGTGTTTTTGGTCGGCGGAGGAACAGCAACAGCTACTCTGACCTCCGATCCTCCAGATATGACCTGCCTGTGAACTCGCATGAGGATGAGCTCAGATCAGACTTTTTTTGTCTATGCTTTTGTGCTCCGATGGATAGAAATATATATAAAAAAAACGTTTTTGGAAAGCAGACTCTTGAAGGGACGTAAATTGGCAAGCACTTAATGTTGTCGGACTTGTTTTGAAGAAATCGCTTTAAACCGAACCCAGCTATGCAGCAACATTGGCATAAAATGCTTCCATTTGTTTTGGTTCTTTTTTTTTCCTTTCCTCAATCAAGTATGGTTGCTCTATTATTCGTTGCACTTTTATTTTGTACGTAATCT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa2507
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000002334 | Nonsense | 1003 | 1071 | 13 | 13 |
ENSDART00000125961 | Nonsense | 1003 | 1071 | 13 | 13 |
ENSDART00000002334 | Nonsense | 1003 | 1071 | 13 | 13 |
ENSDART00000125961 | Nonsense | 1003 | 1071 | 13 | 13 |
The following transcripts of ENSDARG00000020057 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 9 (position 13387169)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 9 | 13139734 |
GRCz11 | 9 | 13110937 |
KASP Assay ID:
554-3063.1 (used for ordering genotyping assays)
KASP Sequence:
GCTGAGAAGATTAAAAAACGTGTGAAGACWCCTTATTCGTTGAAAAGATG[G/A]CGTCCTTCCACATGGGTCGTCTCCACTGATACACTAGAYGGAGAGGTGAA
Long Flanking Sequence:
AAATTCCACTGCATTGATAAGAATCCTGAAACCGTTCGGCCTCAGTTGGCAGCGGCGATAAAGAGCGTAATGACGCTTGTTAGCTAGAACCTGAAGCAGACACTAAACAGGAAGATAAAAAAACAAAAACAGTCAAGCTGCCCACGTGTTTACATTCTGCATGCGGACCCAAGAGGAGATCTGAACCGATCGAACCTGATGATTCAGACTCAAGCGCACGCTGAGAGAGCTAGTGTGGGAAAGGTCAACCACAAATTTGAGTGTGCTGAAATACTACTCTTTGGGCGGGTTGTTTGGAGCAGCACCGCTAGTATTCCCGATTGGCACATTGCAACACGCACAACTGTTTCTCATTGTCGTGGAAGACTGTAATTAAGGATGTTTGTTAAAATGTGACCTTCTTTTTCTGTTTTAGATGAGGCCGTGTCGCAGGAGGGAAAGGCCGGATCAGCTGAGAAGATTAAAAAACGTGTGAAGACTCCTTATTCGTTGAAAAGATG[G/A]CGTCCTTCCACATGGGTCGTCTCCACTGATACACTAGATGGAGAGGTGAACAACAACGGGCACAGCCAGCAGACGATGATGGCAGTAAGTGGAGGTGGTCACCCAAGCGCTGGCCAATCAAAGTCCAGCATCGCCGTGTTTTTGGTCGGCGGAGGAACAGCAACAGCTACTCTGACCTCCGATCCTCCAGATATGACCTGCCTGTGAACTCGCATGAGGATGAGCTCAGATCAGACTTTTTTTGTCTATGCTTTTGTGCTCCGATGGATAGAAATATATATAAAAAAAACGTTTTTGGAAAGCAGACTCTTGAAGGGACGTAAATTGGCAAGCACTTAATGTTGTCGGACTTGTTTTGAAGAAATCGCTTTAAACCGAACCCAGCTATGCAGCAACATTGGCATAAAATGCTTCCATTTGTTTTGGTTCTTTTTTTTTCCTTTCCTCAATCAAGTATGGTTGCTCTATTATTCGTTGCACTTTTATTTTGTACGTAATCT
Associated Phenotype:
Not determined