Busch Lab

ZMP

map3k10

Ensembl ID:
ENSDARG00000055672
ZFIN ID:
ZDB-GENE-050419-112
Description:
Novel protein similar to vertebrate mitogen-activated protein kinase kinase kinase family [Source:Un
Human Orthologue:
MAP3K10
Human Description:
mitogen-activated protein kinase kinase kinase 10 [Source:HGNC Symbol;Acc:6849]
Mouse Orthologue:
Map3k10
Mouse Description:
mitogen-activated protein kinase kinase kinase 10 Gene [Source:MGI Symbol;Acc:MGI:1346879]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa5640 Essential Splice Site F2 line generated Not yet available
sa2969 Essential Splice Site F2 line generated Not yet available
sa9813 Nonsense Available for shipment Available now
sa14946 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa5640
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088309 Essential Splice Site 405 1062 3 11
ENSDART00000136432 Essential Splice Site 328 973 3 11
ENSDART00000088309 Essential Splice Site 405 1062 3 11
ENSDART00000136432 Essential Splice Site 328 973 3 11
Genomic Location (Zv9):
Chromosome 18 (position 35303262)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 36982418
GRCz11 18 36963426
KASP Assay ID:
554-3073.1 (used for ordering genotyping assays)
KASP Sequence:
CTTCCCATCCCCTCCACCTGCCCTGAAGCCTTTGCCCAGCTGCTGGGAGG[T/G]AAGGACAGTCTTTGTTGAGTAATTGTCCTGCAAGGCATCCACTGTTTTCA
Long Flanking Sequence:
TCAATTCGATAATGATTCTTATCAGCGAAACAGAGAGAAATCTCTGATGTATTTCATATTGTGACCACTTATTCTATGCATCTGACATAAGATGGAGATGGACTTGTGGGCTCTGTACAGTATATTTGTACCCATGCACTTAAAAACCATTAACCAATCATTTCTGGAATAAATCAGTAGCATTGCAGTCAATTTATATTCGCTGAACTGAATTAAAAGTCCACTTGAATTGAATTGAGCGTTCGGGAATCAGAATCAAATCGAATCCGAACATCTGAATAAACACAATCTGCTGTCCTCCTCTGTACTTTTATTTAGACTTTTTTTGTCTAATTGTTTATTGTGATCAGTTTTGGAGTGTTATTGTGGGAGCTGCTGACTGGTGAAGTGCCATACCGTGAGATCGACGCTTTGGCTGTGGCCTATGGAGTTGCCATGAACAAGTTGACTCTTCCCATCCCCTCCACCTGCCCTGAAGCCTTTGCCCAGCTGCTGGGAGG[T/G]AAGGACAGTCTTTGTTGAGTAATTGTCCTGCAAGGCATCCACTGTTTTCATCATTTAATCACTTTTCTCCCTGTCTCTATAGAGTGTTGGTGTCCTAACCCACGTGGACGACCTGCTTTTGGGAGTATCCTGAAGAGGCTGGAGGACATCGAGCAGTCGGCCATGTTCCAGATGCCCCTGGAGTCTTTCCATTCCCTGCAGGAGGACTGGAGGCTGGAGATTCAGCAAATGTTTGATGAACTACGAGCAAAGGAGAAGGTGAGGACCAAAAATAGATGCTTGTTTCATGTTTACATCTCAAAGGATAAAAGTGGCAGTACTAGGACTTCTGAAATATTTTTAGTCCCTATTGTATTTCTATTTATCTAATAATATATACAACTATAGACGAAAACACGAAGAGATCACTTGAATATTCTATGGAGTTTCTATGGATGTATTAGACTACATGGGCTCTATTTTGACGGTCCATGTGCAGAGTGCAAAACGCAGGGCGCAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2969
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088309 Essential Splice Site 405 1062 3 11
ENSDART00000136432 Essential Splice Site 328 973 3 11
ENSDART00000088309 Essential Splice Site 405 1062 3 11
ENSDART00000136432 Essential Splice Site 328 973 3 11
Genomic Location (Zv9):
Chromosome 18 (position 35303262)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 36982418
GRCz11 18 36963426
KASP Assay ID:
554-3073.1 (used for ordering genotyping assays)
KASP Sequence:
CTTCCCATCCCCTCCACCTGCCCTGAAGCCTTTGCCCAGCTGCTGGGAGG[T/G]AAGGACAGTCTTTGTTGAGTAATTGTCCTGCAAGGCATCCACTGTTTTCA
Long Flanking Sequence:
TCAATTCGATAATGATTCTTATCAGCGAAACAGAGAGAAATCTCTGATGTATTTCATATTGTGACCACTTATTCTATGCATCTGACATAAGATGGAGATGGACTTGTGGGCTCTGTACAGTATATTTGTACCCATGCACTTAAAAACCATTAACCAATCATTTCTGGAATAAATCAGTAGCATTGCAGTCAATTTATATTCGCTGAACTGAATTAAAAGTCCACTTGAATTGAATTGAGCGTTCGGGAATCAGAATCAAATCGAATCCGAACATCTGAATAAACACAATCTGCTGTCCTCCTCTGTACTTTTATTTAGACTTTTTTTGTCTAATTGTTTATTGTGATCAGTTTTGGAGTGTTATTGTGGGAGCTGCTGACTGGTGAAGTGCCATACCGTGAGATCGACGCTTTGGCTGTGGCCTATGGAGTTGCCATGAACAAGTTGACTCTTCCCATCCCCTCCACCTGCCCTGAAGCCTTTGCCCAGCTGCTGGGAGG[T/G]AAGGACAGTCTTTGTTGAGTAATTGTCCTGCAAGGCATCCACTGTTTTCATCATTTAATCACTTTTCTCCCTGTCTCTATAGAGTGTTGGTGTCCTAACCCACGTGGACGACCTGCTTTTGGGAGTATCCTGAAGAGGCTGGAGGACATCGAGCAGTCGGCCATGTTCCAGATGCCCCTGGAGTCTTTCCATTCCCTGCAGGAGGACTGGAGGCTGGAGATTCAGCAAATGTTTGATGAACTACGAGCAAAGGAGAAGGTGAGGACCAAAAATAGATGCTTGTTTCATGTTTACATCTCAAAGGATAAAAGTGGCAGTACTAGGACTTCTGAAATATTTTTAGTCCCTATTGTATTTCTATTTATCTAATAATATATACAACTATAGACGAAAACACGAAGAGATCACTTGAATATTCTATGGAGTTTCTATGGATGTATTAGACTACATGGGCTCTATTTTGACGGTCCATGTGCAGAGTGCAAAACGCAGGGCGCAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9813
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088309 Nonsense 554 1062 6 11
ENSDART00000136432 Nonsense 477 973 6 11
Genomic Location (Zv9):
Chromosome 18 (position 35297182)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 36976338
GRCz11 18 36957346
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTCTCTAACAGCATCTGTTTGTTTWAGGTTTTGAGCATAAGATCACAGTG[C/T]AAGCTTCGCCCAGTGTGGACAAGAGGAARTGTCAGRGTAGTGAAAGCACC
Long Flanking Sequence:
ATAAAAAGAAAAGACTATAACAATGTACATTTCATGCTGACTTCAAAGGCGCAATATGTGCGTTTTTTTTCCATTAAAATATCCTAAAACAACTTGAACAGTTATATACTGTACTTAGCTGACTTATTTACTTACATTATTATTTAAATATAGAAAAATAAGCAATTTTAATGCCATGTTTATGACAAACAGCGCTGTTTCTTTCCACTTTTCTTTATCTTTATTATATTTTCTTTATCTCAAGTAATCCAGCTATCTTATGCCACTTAAACCGCTTTCAACTTATCTCTGCTTCATGCTAACATGATAATAATTTTTAATATTTTAGCTCATCCAAGAACATGAGTCTCATAGAATGTAATGAATGTCCATCACATCGTCATCAAAATACACCTTTGTTTGTTGTGAATATGCACCCTCTAGTGGCGAAAATGAAATAGTAGCCTTTAAGTCTCTAACAGCATCTGTTTGTTTAAGGTTTTGAGCATAAGATCACAGTG[C/T]AAGCTTCGCCCAGTGTGGACAAGAGGAAATGTCAGAGTAGTGAAAGCACCACTCCTCCAGCCAGCCCAGGGGTCATTCCTCGCCTCAGAGCCTTTCGCTGTAAGTCAAGGCAAAGTCCACTGCATTGTTTGGTATTATGCTAAATAAATACAATAAATTAGGAACAGAGTGCATTGACAGCTAACGCAGGGGTGTCCAAACTTGGTCCTGGAGAGCCGGTGTCCTGCTGAGTTTAGCTCCAACTTGCTTCAACACACCCGCCTGTAAGTGTCTAGTGAATCTAGTGAGAGCTTGATTATCTGGTTCAGGTGTATTTGATTAAAGTTGGAGCTAAACTCTCCAGAACACCGGCCCTCCAGAACTGAGTTTGGACACCCCTGGTTTAAAGCATGCAACTGCAATATCATGTGTCAATTATCAATACCCTGACAAATGTGTACTGTGTCTATGAAATAGCTTAGATTAAGCTATTTTTTTTTACCCATGCTTAATGTAAAGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14946
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000088309 Essential Splice Site 669 1062 8 11
ENSDART00000136432 Essential Splice Site 592 973 8 11
Genomic Location (Zv9):
Chromosome 18 (position 35294399)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 36973555
GRCz11 18 36954563
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCAAAAMATGCTCCTATGACAGCTGGATTCTCAAGCCTAAWTGAAATGGG[T/A]GAGGATGAATCATGTTYAACWTACAGACACAATAAACCCACCTCAGGTGA
Long Flanking Sequence:
GTCATCACACGGGATCAAAACAAATACACGAGGAGAACAAAAACAAACCAACGTGATCAAACAGACACTCCGGAAAAGTGCACAAACCTGCAACTGTGACACCATCCTTCTATCTATCTATCTATCTATCTATCTATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCTATCTATCATTAAAAATCAACCAAACAATCAAGCAAGCAGTCAATGATTCAGTCAGCCAAACAGTCAGTCAGTGAGTCAGTCAATTAATCAACCAGTCAATCATTTTTTCTAATGAATGATAATTAAATAATAAATGATCATAATAATTCTTCCTTATTACAGGCTAAAGTCTCTTGGGGAGGGCAAAGTGTGGTCCTCCAGTGCTCCAAATCTGGGGAAGTCCCCAAAACATGCTCCTATGACAGCTGGATTCTCAAGCCTAAATGAAATGGG[T/A]GAGGATGAATCATGTTCAACATACAGACACAATAAACCCACCTCAGGTGACCCATTAAACAACAACAACAACAAAATAATATTTAAACATGAACTAAATTAGTTAGTCTTAGTCATTACTATTTGAATTAGTTATTTAAAAAGAATTTAAGTTAAATGACACCCTCATTTGTTGTGTGTAGAGGAGCACTGTGAGTTTGATGACAGTTCTCCAGGGCGCCTGGCTCCTGATCTGGGCAGTAACGGTGCGCTGGAAGACGTGGGCTCGGGATCAGCAGGTTTAGGGTCAGGAATAGGCTCTCAGGATTCAGTTTGCCGCTGCAGCCAGAGGAAGAAGAGTGACCTGCTGTTGCTGGGCTGTGCCTCTCTACTGGCCGTTGTGGGACTCGGTTCTGACATCCTCCAGTTGGGACGACAACAGGTACACACTGCGAAAAAGTGAGAAGAGTTACTAATGAAGGAAAAGAGTCTTAAGAGGATTGATTATAACTGCTTATAAAA
Associated Phenotype:
Not determined