Busch Lab

ZMP

mertk

Ensembl ID:
ENSDARG00000074695
ZFIN ID:
ZDB-GENE-081107-1
Description:
Novel protein [Source:UniProtKB/TrEMBL;Acc:B8JME4]
Human Orthologue:
MERTK
Human Description:
c-mer proto-oncogene tyrosine kinase [Source:HGNC Symbol;Acc:7027]
Mouse Orthologue:
Mertk
Mouse Description:
c-mer proto-oncogene tyrosine kinase Gene [Source:MGI Symbol;Acc:MGI:96965]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa22378 Essential Splice Site Available for shipment Available now
sa561 Essential Splice Site Available for shipment Available now
sa28202 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa15250 Essential Splice Site Available for shipment Available now
sa18550 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa22378
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109266 Essential Splice Site 510 952 10 19
ENSDART00000142729 None None 150 None 2
ENSDART00000109266 Essential Splice Site 510 952 10 19
ENSDART00000142729 None None 150 None 2
Genomic Location (Zv9):
Chromosome 13 (position 48134986)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 47385872
GRCz11 13 47675697
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGATCGTGTTGTGTTGGGTGGTGTGGCTGCACAACAACTCTTATTTACC[G/T]TAAGCTCATTTCTTGTTTTCTCATTCAACATGAAATCTAAAGTAACGCGG
Long Flanking Sequence:
ACAGTGCTAGTCACTGGGCCAACGTGCCGCCCATTCTGGATAAAGGAGGAAAAAGGGGAGAAGGGGGGTTTCTTCCAGACGAAGATAGTTGTAGAAAGGAAATGAGGAGATATATATAGTGATTTGGGATCCTTTGATTGGAGGATCATGATTAGCTAATTTGGACCAGCTGGGTCAATCATGAGCACATGCACATCTCGAAAATAGTTTAAAATTAAACTTCACTTAAATCTAATACAAACTTTCATGAACCTTGTCAATACAGGAGTTTTATTTCTCCATGTTTGTTTCATGGATTTTTGTTTTTTTGTTTTACCCTGTTGTTTATTAATTTTGAAATGCATGCATCTGTGTTTTGCAGATTCGCCTGATTCTCCATCCTCGACTCCGCTTCCCAATCGTCCTGATTCTGCCTTCATTGTTCTCGGGGTGGTTTGCGGTTTCTTTCTGGTGATCGTGTTGTGTTGGGTGGTGTGGCTGCACAACAACTCTTATTTACC[G/T]TAAGCTCATTTCTTGTTTTCTCATTCAACATGAAATCTAAAGTAACGCGGCTTAGTACCTTATTTATCAGGGGTTACCACAGTGGATTGAACCACCAACTATTCCAGCATATGTTTTACACAGCAGATGCCCTTCCAGTCACAATCCAATATTGGGAAACACCCAATCCCATTCACTTACACACACACACACACACACACACACACACACACACACACACATATACACCACGGACAATTTAGTTTATTCAATTTACCTGTAGCGCATGTGTTTAGACTGTGGGGGAAACCCACGCCAACACAGGGAGAACATGCAAACTCTACACAGAAATGCCAACTCACCCAGCCGGGACTCGAACCAGTGACCTTCTTGATGTGAGGCGACAGTGCTAACCACTGAGCCATTGTGCCGACCCACACAATTGCAAGATGTAAACACTAAATTTTGAGAAAGCAAAAAAAAGATAAGAAAGAAACTCAGATTTCTGCTAAATAAAAGTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa561
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109266 Essential Splice Site 510 952 10 19
ENSDART00000142729 None None 150 None 2
ENSDART00000109266 Essential Splice Site 510 952 10 19
ENSDART00000142729 None None 150 None 2
Genomic Location (Zv9):
Chromosome 13 (position 48134986)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 47385872
GRCz11 13 47675697
KASP Assay ID:
554-0471.1 (used for ordering genotyping assays)
KASP Sequence:
GTGATCGTGTTGTGTTGGGTGGTGTGGCTGCACAACAACTCTTATTTACC[G/A]TAAGCTCATTTCTTGTTTTCTCATTCAACATGAAATCTAAAGTAACGCGG
Long Flanking Sequence:
ACAGTGCTAGTCACTGGGCCAACGTGCCGCCCATTCTGGATAAAGGAGGAAAAAGGGGAGAAGGGGGGTTTCTTCCAGACGAAGATAGTTGTAGAAAGGAAATGAGGAGATATATATAGTGATTTGGGATCCTTTGATTGGAGGATCATGATTAGCTAATTTGGACCAGCTGGGTCAATCATGAGCACATGCACATCTCGAAAATAGTTTAAAATTAAACTTCACTTAAATCTAATACAAACTTTCATGAACCTTGTCAATACAGGAGTTTTATTTCTCCATGTTTGTTTCATGGATTTTTGTTTTTTTGTTTTACCCTGTTGTTTATTAATTTTGAAATGCATGCATCTGTGTTTTGCAGATTCGCCTGATTCTCCATCCTCGACTCCGCTTCCCAATCGTCCTGATTCTGCCTTCATTGTTCTCGGGGTGGTTTGCGGTTTCTTTCTGGTGATCGTGTTGTGTTGGGTGGTGTGGCTGCACAACAACTCTTATTTACC[G/A]TAAGCTCATTTCTTGTTTTCTCATTCAACATGAAATCTAAAGTAACGCGGCTTAGTACCTTATTTATCAGGGGTTACCACAGTGGATTGAACCACCAACTATTCCAGCATATGTTTTACACAGCAGATGCCCTTCCAGTCACAATCCAATATTGGGAAACACCCAATCCCATTCACTTACACACACACACACACACACACACACACACACACACACACACATATACACCACGGACAATTTAGTTTATTCAATTTACCTGTAGCGCATGTGTTTAGACTGTGGGGGAAACCCACGCCAACACAGGGAGAACATGCAAACTCTACACAGAAATGCCAACTCACCCAGCCGGGACTCGAACCAGTGACCTTCTTGATGTGAGGCGACAGTGCTAACCACTGAGCCATTGTGCCGACCCACACAATTGCAAGATGTAAACACTAAATTTTGAGAAAGCAAAAAAAAGATAAGAAAGAAACTCAGATTTCTGCTAAATAAAAGTC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa28202
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109266 Essential Splice Site 669 952 15 19
ENSDART00000142729 None None 150 None 2
Genomic Location (Zv9):
Chromosome 13 (position 48143130)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 47394016
GRCz11 13 47683841
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGATCTGCACAGTTACTTGCTCCGCTCCCGTCACGGGGAAGATACTGTGG[T/C]AATAATACTAAAGAAACAGTATTACTGTTTATTTCTTGCATGAACCAAAG
Long Flanking Sequence:
GTAAGAGCTTGATTAGCTGCTTCAGGTATGTTTGATTAGGGTTGGAGCTAAACTCCTCAGGACACCGGCCCGCCAAGACCGAGTTTGGACACCCCTGAACTAGATAGTCCAGACAGAAAATATAAAATGTCTCATATCTGATTAATGTCTGCCTTTTTTAGTGGATAACTTCTCCCAGAGAGAGATTGAAGAGTTTCTCAATGAAGCTGCTTGTATGAAGGATTTTCACCATCCGAACGTCATCAAACTCTTGGGTAAGAAACAACCATTGTTTCTAAATACACTATAAATGCTCTTTATTATCAGAAAGAGTGAAAACAATCTGATATAGATGTGCAAGCGGTTTTTAAATCCACATTGTGCTGATTGTGTTTCTGTAGGTGTTTGTTTGGAGGTTGGATCTGGACACTTTCCGAAACCAATGGTTGTGCTTCCCTTCATGAAATATGGAGATCTGCACAGTTACTTGCTCCGCTCCCGTCACGGGGAAGATACTGTGG[T/C]AATAATACTAAAGAAACAGTATTACTGTTTATTTCTTGCATGAACCAAAGTGTGCTGAGGGCCTGTGCCATGATGGTGGCTTAACGAACTCAGGATTTATGAATTACTTTTTAATGGCGCAGTATGTTATTACCACTAGAGGGAGTGTATTGACCATAAACAAAGATGTATTTTGATGATGTGTGTGGAATCATGGGGGTTTTGCTTCTAGAGTAGACCGAAATGAAATACACCATTTTCCATTAAGTCAACCTGGAGTGCTGAAATATAATTGGGTAAATTGGCAGTGGGCTGGTTATAGAGACCAAAACAAAGACAGACATTATACAGATGACACAGGCTCCTGGCCTAATAGGATGTTGTTTTTCCAGTATCTCCCCATGCAGATGCTGCTGAAGTTCATGATAGACATCGCTCTGGGAATGGAGTATCTCAGCAGCAGAAACTTCCTTCACCGAGACCTGGCCGCACGAAACTGCATGTATGTGTCCTCAACTTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15250
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109266 Essential Splice Site 706 952 16 19
ENSDART00000142729 None None 150 None 2
Genomic Location (Zv9):
Chromosome 13 (position 48143613)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 47394499
GRCz11 13 47684324
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCAGCAGCAGAAACTTCCTYCACCGAGACCTGGCCGCACGAAACTGCATG[T/A]ATGTGTCCTCAACTTATAGTCTATTGACTAATTTAAAAATCGYGTGAAGT
Long Flanking Sequence:
CGGGGAAGATACTGTGGTAATAATACTAAAGAAACAGTATTACTGTTTATTTCTTGCATGAACCAAAGTGTGCTGAGGGCCTGTGCCATGATGGTGGCTTAACGAACTCAGGATTTATGAATTACTTTTTAATGGCGCAGTATGTTATTACCACTAGAGGGAGTGTATTGACCATAAACAAAGATGTATTTTGATGATGTGTGTGGAATCATGGGGGTTTTGCTTCTAGAGTAGACCGAAATGAAATACACCATTTTCCATTAAGTCAACCTGGAGTGCTGAAATATAATTGGGTAAATTGGCAGTGGGCTGGTTATAGAGACCAAAACAAAGACAGACATTATACAGATGACACAGGCTCCTGGCCTAATAGGATGTTGTTTTTCCAGTATCTCCCCATGCAGATGCTGCTGAAGTTCATGATAGACATCGCTCTGGGAATGGAGTATCTCAGCAGCAGAAACTTCCTTCACCGAGACCTGGCCGCACGAAACTGCATG[T/A]ATGTGTCCTCAACTTATAGTCTATTGACTAATTTAAAAATCGCGTGAAGTGAGATGTTTGATCTAATCTCAACTGAAACATGAAGAGAGGGTGGGACATAGAGTAGCTCCTCCCTCTTTTAAAGAACAGCCAATAGTGTTTTGTTTTATCACTGCTCTGCCAGGGAGAGTGGTTGGGCTCAAGCGCATCAAATGAAAAGCGAAGCGTCTTTAAGGGGGCGGGGCATGTCAGACTCTAGAGAGCATTTGATTGGTCAGAAGATTTGATGATGAACTGAAGTATGAGAAAAAGCTTCAGTTTGACTCAAAACATTGACCTATTTAGGTGGAAGTGACAAACTGCAAGCTTCATATGTTTAGATCAGGTTTATGCACCAATATTCCGTATATTACCCATATTCACTGTGAATAGGATAAAAATATTCATTTTCAAAATGAGATGTACTCATTTATGATGAGTACTGTATTTATAATAAACTAATAATGTACAGGGTGGGCCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18550
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109266 Essential Splice Site 706 952 17 19
ENSDART00000142729 None None 150 None 2
Genomic Location (Zv9):
Chromosome 13 (position 48146239)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 47397125
GRCz11 13 47686950
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACCYTCTAAGTGTCAGNNTANTTTTTTTATGCATGTTGTGTTTGTTTTGTCT[A/C]GGTTGCGTGATGACATGAGYGTGTGTGTTGCTGATTTCGGCTTGTCAAAG
Long Flanking Sequence:
ACTGCGCTCATTTCTGGTGCCCCCCGGGATGTACAGCGCCCTTAGCATTGGCCTATCCTGCCTATGCCACTGGCCGGCCCTGATCATGTAGCAATTTCAAATATCCAGTGACCTTGAGGTTTCCATTGATAAGGAATGGTCCCACTATCTTTGTTGTCTTTGGTGTGAAGATACAAGATGTGCAGCACCTGAAACTATGGATTATAAATGAAGTGTTCAGAGACTTCTTTCGGGAAAAACTTACTAAGCCCTGAATTTTTATTCCTAGTGTGAGACTTGCGAGGACTCTGTCAAGTCACTTTTATTTCTGAAGCAATTATACAATGTAGATTCTGTGTTGAGGCTGCTTGACATGAACAAGAAATGGATAAACAGTCATAATATTTCAGTCTGTGGGACAAATTCAGCACCTTAGGCAGTGGCAGAGTAGCGATAGTGACTGATTTTGTCAACCCTCTAAGTGTCAGTATTTTTTTATGCATGTTGTGTTTGTTTTGTCT[A/C]GGTTGCGTGATGACATGAGCGTGTGTGTTGCTGATTTCGGCTTGTCAAAGAAAATCTACAGCGGTGATTATTACAGACAGGGCCGGATAGCCAAAATGCCTGTAAAATGGATTGCCGTGGAAAGCCTCGCTGACAGAGTCTTTACTGTCAAAAGTGACGTGGTGAGAGATTTTACAACATCTTTGTTTTTAGTCTCTACACCTGCTCTGTCTTAATTAAAATTCAACTACCTTCTGTTTTTATTGTTTTAAAAAAAGTCTTGGGTGTCTTCCAAAGTTGCATCGCTGAGTAAATGTTCAGTTTTTGAAGTTTATCATCTTTTAATGTACTTTTCAGTGGGCGTTTGGAGTGACCATGTGGGAAATCGCCACTCGAGGAATGACCCCGTACCCGGGCGTACAAAACCATGAGATTTATGATTATCTCCTTGAGGGGAACAGACTGAAACAACCAAACGACTGCCTGGATGAACTGTGAGTTTGTTTAATAAATGTGTTTCC
Associated Phenotype:
Not determined