ZMP
mthfd1
Ensembl ID:
ZFIN ID:
Description:
C-1-tetrahydrofolate synthase, cytoplasmic [Source:RefSeq peptide;Acc:NP_955823]
Human Orthologue:
MTHFD1
Human Description:
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase
Mouse Orthologue:
Mthfd1
Mouse Description:
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase,
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa473 | Nonsense | Confirmed mutation in F2 line | Not yet available |
Mutation Details
Allele Name:
sa473
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021950 | Nonsense | 615 | 934 | 19 | 28 |
Genomic Location (Zv9):
Chromosome 17 (position 49524061)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 17 | 49285145 |
| GRCz11 | 17 | 49368120 |
KASP Assay ID:
554-0205.1 (used for ordering genotyping assays)
KASP Sequence:
GGAAGTTTTGTTTGTTTTAGGGAGTGTGTGGAGCTCTGACAGTCCTCATG[C/T]GAGATGCTATCAAGCCAAACCTCATGCAGACTCTGGAGGTGAGTGTTGTT
Long Flanking Sequence:
AGGCTGGTCAAGCTGGTATTAGCTGGTCATCTCCCAGCCTGACCAGTTAAGACCAGGCTGGAAATGGCTGGAAACCAGCCTGGAAATGGCCAAAACCCCTCTAAAGCCAGGCTGTTCAACCAGCTAAAATCAGCCAACCAGCCTAGGCTGGTTTAAGCTGGATTTTTCAGCAGGGAAAGCATGTTTACCTATTCTGTCAGAAGACAGTAGGCAGTACCTGAGTGTTTTACTGGTATTGTGTTGCAGGCCCAGTTTGACATCACTGTTGCCAGTGAGATTATGGCAGTTTTGGCTCTCACTACCAGCCTGGAGGACATGAAACAGAGGCTAGCCAAAATGGTAGTTGCCACCAGTCGCAGCGGTCAACCTGTCACCACAGAGGACTTGGTATGCTGGCGTTTTGGTTTACTTTATCTAAAGAAATGTCACGTTTCAGCCTGCTCTTATTCTGGAAGTTTTGTTTGTTTTAGGGAGTGTGTGGAGCTCTGACAGTCCTCATG[C/T]GAGATGCTATCAAGCCAAACCTCATGCAGACTCTGGAGGTGAGTGTTGTTGTACAGGCTTGTGTGTGTATTTAAGTTAATTTAAGTTCATCTGGGCATATAAAGGCCTTGAAGGCCTCATAACTTAAATAACCAAATTTTCCCAGATTAAAGGGTTTAAAAAATTGTTTAATTCTGGCCTGAAGACAAAAAATCAAGAAGCCCCTGCTGAAAAATCCAGCTTAAACCAGCCTAGGCTGGTTGACCAGGCTGGTTTTAGAGGGGTTTTGGCCATTTCCAGGCTGGTTTACAGCCATTTTCAGCCTGGTCTTAGCTGGTCAGGCTGGAAAATGACCAGCCAAATCCAGCTAAAACCGGCTTGGCCAGCCTGGTTTAAGCTGGATATAGCTGGTTTTTGCAAGACTCCCACCTTGGCTAGGCTGGTCAAGCTGGTTTTAGCTGGTCATCTCCCAGCCTGACCAGCTAAGAAGGCTGGAAATGGCTGGAAACCAGCCTGGAAAT
Associated Phenotype:
Not determined