Busch Lab

ZMP

eml2

Ensembl ID:
ENSDARG00000008808
ZFIN ID:
ZDB-GENE-050706-71
Description:
echinoderm microtubule-associated protein-like 2 [Source:RefSeq peptide;Acc:NP_001025406]
Human Orthologue:
EML2
Human Description:
echinoderm microtubule associated protein like 2 [Source:HGNC Symbol;Acc:18035]
Mouse Orthologue:
Eml2
Mouse Description:
echinoderm microtubule associated protein like 2 Gene [Source:MGI Symbol;Acc:MGI:1919455]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa42566 Nonsense Mutation detected in F1 DNA Not yet available
sa45543 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa42565 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa32039 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa42566
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017268 Nonsense 189 833 4 22
Genomic Location (Zv9):
Chromosome 15 (position 28247880)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 28966120
GRCz11 15 28898996
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCGATTCCCGCAGCAGAACCACCTCATCCAGCAGTTCAACATGCGGAAAG[A/T]GAGACAGGTACCTTTTTTATGAATAAAGTGCAGTTAGATTTTTCTTGTAC
Long Flanking Sequence:
GTCAAAATTTCATACTGCACCTTTATTTTCCTTCAGCTTAGTTTCTGATTTATCTGGGGTCGCCACAGTGGAATGAACTGTGAACTACTCTGGCATATATTTTACGCAGTGGACAACCCAGTACTGGGGGAAAACAGTATTTATTTAGAATAGAAATCTTATCAATTGATCAATGTATGGATTCTTGGAAAAAACATTCATTAAAAATTAATAAAAAAAAACACATGTATGAAGTTCATAAGTTAATTGAGATTAAACATGCATTTTAAGGTGGTGTGATGTCATATTTTCTGCCTAGCCCAAGACCTGTTTTGTCCTCCTGTTTCTTTGATGTCTTTCTCACCTGCCCTCTGCATTGTGCCTCAGTCATTGTCTTCCTCAAGCTTTGGTTTCTGTGTGTCAGGAAGAGCATGTCCACTGAACGCCTGTCCACAGTGAAGAAGGAGATGGCCGATTCCCGCAGCAGAACCACCTCATCCAGCAGTTCAACATGCGGAAAG[A/T]GAGACAGGTACCTTTTTTATGAATAAAGTGCAGTTAGATTTTTCTTGTACTCTACATAGAATTGAAGTTCAGTCATTTTCCTTCGCTCTAAACCGTTAGGCTAGTACAAGACGTCAACACAGCTAAAAATAGATGCTACCTCAGTGTCTAATTAGATAACAAGTCCAGACCTTTGGTTAGCAAGCACCAGAAACAGTATAATGGGAATGAGGTGGAGTATCCATAAAACATTTTCTTCTATAATTTAAGCAAAATCAAAATGAAAGGCTGACATTTTTATTCTCATGGTATTGATATTTTAAAATATGCTATTAAGTGTACAGTTTTGACTGTTTAGTTCTAACTTACAAATAGAATGATGTTATACTTGCATGCTGATTCTGTGCAGAATGCCTGTTTTCTAGATATAAAAATACACGACTACAGAAATAGTTAAAAAGCTTTCTTAAACACATCAACATGACCAAAAGGGAGTTTTATGTTACAAACAAACTATTTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45543
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017268 Essential Splice Site 294 833 8 22
Genomic Location (Zv9):
Chromosome 15 (position 28240785)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 28959025
GRCz11 15 28891901
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGGGAAATCTTTTCTGACAAGCTCTGATCCTGTCAATGTTCTCTTTGCA[G/A]TTTGGCCATCCATCCAGACATGGTCACTATAGCAACAGGACAAGTTGCCG
Long Flanking Sequence:
AGAGATGGGTTGCGGCTGGAAGGTAAGGCCGCTGCGTAAAACCATTTGCTGAATAAGTTGGTGGATCATTTCGTTGTGGCAACCCCAGAATAATAAAAGGACTAAGCCGAAAAGTGAATGAATGAATGAATGAATTATATTCTTTTTATAAGGTCACAGGCAGTTGTACAGTATAAGCATTTCATTGCACATTTTACAGTGTATGGCTGTGTATTTGAGAAATAAATTTTTATTTTAAATAAAATTCTGCTGCAACAGAATGTGAACATGGTATTTGTATATATAAAATATTAGCTAATTATCATTTGTTGCTAATTAAAATAACACTGGAATGCTCTTTCTCCCTTTGACTGTAAGAGTCCGTGCTGGTTTGCAAAACTGTCTGTTTACTGCTTTTTTTGGGGGACTGAACTGCATTCATTTGCTGTTCCCTGAGAGCGAGAGAGTGGAATGGGAAATCTTTTCTGACAAGCTCTGATCCTGTCAATGTTCTCTTTGCA[G/A]TTTGGCCATCCATCCAGACATGGTCACTATAGCAACAGGACAAGTTGCCGGAACATCCAAAGATGGCAAAGTTTGTTCACATTTGCATTCTGTGGCATGTGTGCTGAATTTTTTATTTTTTTGGATGCATTGAATTGATCAAAAGTGACAGAAATATGATGATAATGTTATTAAACACTAAATTTTATTATTTGGGCTTTCTGTTTTTCATCAAAGGCTCTTAAACTGATAATAATACAGGAATATTAAATTTCATTAAACAATTATGCTTTTAATTTATTAAACATTCAATAAATAAAATATTTGTTAAAATGTTTATAAAATAATTATTAATAAATATAATATAATTTCTTAAATCTTTATATATATAAGTATATTAATCATATTTAGTTTTATTAAATTAATTAAATTTATTTTTTTCAATTAATAAAATGAAATGTGCACAAAACAAAGTATATTAGAATGATTTTTGAAGGATAAGGTGACAATGAAATATTGGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42565
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017268 Essential Splice Site 318 833 9 22
Genomic Location (Zv9):
Chromosome 15 (position 28239614)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 28957854
GRCz11 15 28890730
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATACATAAATCCTTAACAGTACACACAACTCAATCGTTGTTTTCCCATC[A/G]GGCTCTGCCACCTCATGTCCGTGTCTGGGACTCTGTCAGTCTGAACACTC
Long Flanking Sequence:
ATAAAATCCAAAATTCCATCCCAGATATAAAACAATATTTGTACACATACACACACATACAGTTGAAGTCAGAATTATTAGCCATCCTTTAATAATTTTGACCCTAAAATGGCTGTTAGATGAAATAAAACAAATAAGACTTTCTCTAGAAGAAAAAATATTTTCATGACATAAAAAAACGTGAAAATTTTCTTGCTCTGTTAAACATTATTTGAGAAATAGTTTAAAAAGAAATTGGGATGGGGGGTAGGGGTCTTCAATTCTGTCTTCAATTGTATATACATATATATTTTTAAACATTTACAAAATCATTAGTCGCATAAACATTAGTCTATTCTGGCAAAAAAATGCAAGACTATAACCATTCACACATGGTGTAAATATGAATTTACTACTTTCTTTTGTGGAATTACATAAATGATTCATTCAGTGTTTCAATTCCATTTTAAAAATACATAAATCCTTAACAGTACACACAACTCAATCGTTGTTTTCCCATC[A/G]GGCTCTGCCACCTCATGTCCGTGTCTGGGACTCTGTCAGTCTGAACACTCTTCATGTGATTGGAGCAGGTGTGTTCGACCGAGCTGTCACCTGTGTTGCCTTCTCAAAGTCGGTAAGCTAACTTTTATATAGTGGTTTTTTAATAAATCATCCGTGTGGTTTGCTGCCATGCTGCATATGGGGAATAGTGCACAATGGGTATAACATAATGAACATGTGATGAATGGCTGAATTAACAATGGTGTTTTACATGGAAATAATACCACTCCTCTTCACAGAATGGTGGAGCTCATTTGTGTGCGGTTGACGATGCAAATGATCACATTTTGTCAGTTTGGGACTGGCAGAAAGAAAAGCAGCTTGCCGAGGTTAAGGTGAGGTGACATATAGTTGAAGAACAAATTATTAGCCTTCCTTTAAAATTGATTCTTTTTCAAATATTTACAAAGTGATGTTTAACAGGCCCAGGAAGGAAATCTATATTTTTTCCACAGTATTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32039
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017268 Nonsense 823 833 22 22
Genomic Location (Zv9):
Chromosome 15 (position 28230522)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 28948762
GRCz11 15 28881638
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAATGTTGCCTTTCTGCATGACGACAGTCATCTTATTTCTACCGGTGGG[A/T]AGGACACCAGCATTCTTCAATGGGTGCTGGCTTAGTCTGATCTGAGCCCT
Long Flanking Sequence:
GTACCGAGTATTATTTATGTTATCTATTAAATTACCCAATAAAATGTATTTTTTAACGTCTCCCCCCTTTCCAACCATCACAGTACTGTAAAAATATGAATTATTTTTATACAGTGTCATAAAAATGCTTCTATATTGATGTGCATATCACACTTCCGACCAGCCATGCATCCTATCTAGATTTTAACCAAGCGATTAAAACTTCAGGCTTTTAGACCTACTTGAAACTTTTAGACTAGGCTTTAGCAACAAACCTTTTTTTATCTATATTTGTAAAAATAGCTAATGTTTATTTCATTTGAAGTAACACACTTTAGTCTCATGCTTTTGGTTTTATTGACCTGTATTGACCATTGTTATATTTGCCATTTAAATTAAAAATTAATAATTCTATATATTTTTATCTGCAGGCTCCCAGCCACATCTATGGTGGGCACAGCAGCCATGTGACCAATGTTGCCTTTCTGCATGACGACAGTCATCTTATTTCTACCGGTGGG[A/T]AGGACACCAGCATTCTTCAATGGGTGCTGGCTTAGTCTGATCTGAGCCCTCACTGTAAACTCCTGCCCACTAGAGGGCAGCACTGCTGTGCCTAATTCTCTGCTGTCTGTTTGCCTGTATTGTGTACTGTATCATTAGGTTTTCCATTACGTGCTGGTCCAGAGTCAGTTTTGCCTCTTGCCCGGGTGTAATTATGGGGATTGTCTGAGGGTTAGAGGCTGAGCTTGCAATCAGAGTTGAATGACCACTAGAAGGAGCTCTGGTGCAGGAGAAGAAGCATGTTGTCTACTGTTGACTATTTATGCCTATTTAAAGAGTTTTAGCTGCTATTTGTGTTGCCGAAGCCTATAGAAATACATAATGCTGTCACTTAGTGGAGGCTGTATTTTAATATTAAAAGTACATGATAATGTTGTGGCACTTAGCTTTTGATGCATATCTAGGGGTGAACTTAAGCTGTGCTTTGCCTTTTATTTGTTAATAAAGTTTCTCATAATGAA
Associated Phenotype:
Not determined