Busch Lab

ZMP

AATK (2 of 2)

Ensembl ID:
ENSDARG00000077477
Description:
apoptosis-associated tyrosine kinase [Source:HGNC Symbol;Acc:21]
Human Orthologue:
AATK
Human Description:
apoptosis-associated tyrosine kinase [Source:HGNC Symbol;Acc:21]
Mouse Orthologue:
Aatk
Mouse Description:
apoptosis-associated tyrosine kinase Gene [Source:MGI Symbol;Acc:MGI:1197518]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa35358 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa22160 Nonsense Available for shipment Available now
sa42084 Nonsense Mutation detected in F1 DNA Not yet available
sa45475 Nonsense Mutation detected in F1 DNA Not yet available
sa11207 Nonsense Available for shipment Available now
sa19043 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa35358
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111560 Essential Splice Site 146 1657 4 14
Genomic Location (Zv9):
Chromosome 12 (position 38056826)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 36021842
GRCz11 12 35716097
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAGAGTTTGCTCTACATTAAGGAGATTGGAAATGGCTGGTTTGGCAAGG[T/C]AAATCTAGTCAGTTTGTTGTTTCATTTGTTTTATATGTGCGCCTCGCAGA
Long Flanking Sequence:
TCACCCCTAAAAATAGTGAAATAACTGAACATAAATATAGGAGGCTACGAAAATAATAATTTCAGATGGCACTTAGAGGCTGCATTGAGCTCAATATATATAGGATTAAGAAATGGCAGAGTTTTAATTTGGATTGGAAGTCAATAATGACAGTTTTCAATTATTTTTATTTTTTTTTTTACATCCAGTAAAGTCTTGATGACAGCAGAATTGTCTCAAAGTTTGAGAATGAATCAAAGACCATCTTGTACTGTACCTAAAAATCGAATTAATTCCTTCATTTATAGTATGTTCTGTTCTTTATTTATGTTTTCTATCTAAATGTTCTAGACTCTGAGTGGCAGATCTTCTGTTTGGCCCATTAACTAATTACTGTCTTGTTCTGTCTCTGTCTTTTCTTGCTGATAATGGTCTTTCAGTCCAGCTCCTGAGATCCACCGATCTTGGCCGCCAGAGTTTGCTCTACATTAAGGAGATTGGAAATGGCTGGTTTGGCAAGG[T/C]AAATCTAGTCAGTTTGTTGTTTCATTTGTTTTATATGTGCGCCTCGCAGACATCAATGCTCTAAGCATGTACTGTACTGCAGCGGATCAAAGGTTTAGCTCTATAGTTTAGTCCCGAGGATGTGAAAATATCGTCCATGCTACATTACCAGCTCCTCGTCTGTGCTTTGATGTTGGGCCGGTGTCTTGACTGTTCCCTCAGAGAATTTGATGTTATTTCTATGTAGCAGTGAAGCAGTTTAAAATTTCACAGGAATAACTGAGCCTCTTTCATTCTCATTCTCTCTTTCTTTCTCTCTACTTCTTTGTCTTTTGTAACACACATACATAAACACACACACTTCCCCAATTACCCCAACTTCCCATTGAATGGGTATGTCCATCTGTATGTGTGTCTCTGTGGCTGCATGTTTACCAATGTCCCATCTGGTTTTGTGTTGTTTGGTCTGTCTGCGTTTCCATTTGAGCATGATTCCTGGACTTCTTTTGATCCTTATTTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22160
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111560 Nonsense 353 1657 10 14
Genomic Location (Zv9):
Chromosome 12 (position 38064202)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 36014466
GRCz11 12 35708721
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGGAGCTGTTTGAGTTAGGGAATCAGCCGTACCGCCATTATTCAGACCGA[C/T]AGGTTCTCAGTTATGCTGTGAAGGATCAGCAATTGAAGCTGTCCAAGCCT
Long Flanking Sequence:
TACAAGGCATGTACACTTTAATCTATACTTTTTTATTACTTTATCAATAACAAAGTCCATTATACGAATAATACTAACATGTAAGCATGACTTTCAGATTTTCATAGTTTCATAGATACTTTCATAGTTTGTATATTTTATTAACATTAACCATAGCCCCCTCTCTTCATGTTTTTTTTTTTTTTTTCCAGGATGACTACTTTGTGACATCAGACCAGACCTGGGTACCTTTACGCTGGATTGCCCCTGAACTGGTGGATGAGGTTCATGGCAATTTGCTGGTAGTGGACCAAACCAAGGAAAGCAACATCTGGTCAGTATATTTAGCGTATTTAGGCAGTTTAGGAAGAATAAATCATTTTTATTGTTGAATATAAATGCATTAATTGCTGTTATTTTCCAGAGTTCTATGTTCTTCTCTGTTTTTAAGGTCACTTGGTGTAACCATCTGGGAGCTGTTTGAGTTAGGGAATCAGCCGTACCGCCATTATTCAGACCGA[C/T]AGGTTCTCAGTTATGCTGTGAAGGATCAGCAATTGAAGCTGTCCAAGCCTATTCTTAAGTACCCACTTGCTGACCGCTGGTGGGTGTCTAATAAACTTTATATAGCTCTTCTTACACAATCCATTTACCATTACTTAGAGTTAGAGCCTTGACTTTTTGCTTCAGTAGAGCTTTTCAATCTTCACCCCTCTCTTTTGTAAAGTCCGTGCCCTTAAACACATTAAATATTGCACTTTTTCCATATTTGGATCTTATTCATTACATTTTGCTGTAAATTCAAATACTTCAAATTTCTTTTATATAATGGAGGATTTACAGTGCAAAACAGACAGATCAAAAAAGAAACAATAATTCACTTTTTATTTACAGTATATTTTTGTCGCATTTGCACTAAAAGTGTATGTGTTTTTGTCATCAGGTATGAAGTAATGCAGTTTTGTTGGCTTCAGCCTGACCAAAGGCCCAATGCAGAAGAAGTTCATCTTTTGCTTAGTTACTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42084
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111560 Nonsense 688 1657 11 14
Genomic Location (Zv9):
Chromosome 12 (position 38065546)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 36013122
GRCz11 12 35707377
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTATTACTTTGAACCATCACCTCCTAAGGTTATGGGCCGCTATATGATA[C/T]GAGACTCAACAGAAACTCTACAAGAAAGCTGGGGCTCTCGAAGTCTGAGA
Long Flanking Sequence:
CAGGAGGAATAGTGGGGGGATGTGCTGTTGATGGACTTGCCCTAGGGGTTTCTCCTTCATATTATGAGCCCAAACAATTACACACCCCTGGTGTGGTGCCTGTGCTGAGTGCTCATAGTCCATCAGTGAGTAACGAGTACTATATTCGCATTGAGGAGCCAGTACAAAGCAATATTGATATGAACTTTACCATGTGTGCTTACAGCCCAGAGTTTGGTGGCAGTAATGGAAGCTTTTTAACCGGTAGTGGAGACTCTGGTGAGTGTATGAACTGTCCCCCTGAGGCTAAACCAGACATTTACTGGTCAGCTGAAGTTCACAAAAGTGGTGCTTATGATTCTGACTCCAGCCCTGCTATGTCTTTAACTATGGAGCCTCTTTTGGGCCACGGTAGCCCCCTTAGAGCATGGGAATCAGGCCACTATGTCTCATACAAAGACAGGGATGGAGGTTATTACTTTGAACCATCACCTCCTAAGGTTATGGGCCGCTATATGATA[C/T]GAGACTCAACAGAAACTCTACAAGAAAGCTGGGGCTCTCGAAGTCTGAGACAAGCACTTGGGGAACTGGAGGACCCTTTAGGCATCTCACCATCACTTGGAAGTCCTCCACAAGGCTATGCTGATCCTTATTTGGAGAGCATTCAAGGCTCCATTATAGGAAAGAATGTAACGGGTGGATACTATGATATGATGGGCTCTTTGAGAAAGACTATGCCAGGTGGCCACTCTGTTTGTACTGACATAGCATCAGGTGGTGCTGTATTTGTAGGTCGAGATGACAGCGAGTCTGATGAAGAGGAAGACATCTTTGTGGAGAGGCGAGGAAGAAGCTGGTCTGCCAGCAATCCACCAAATACAAACCCAAGGACCTTGCGTCAGAGGCAGGGGTCTTGTATCCAGGATTCCTATGCAGACTTCCACTACACTATGCCAATGACTGATATTGAGGATACATGGCCAGAGCAGCAGACCCTGTCATACCATATGACCAAACCTGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45475
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111560 Nonsense 795 1657 11 14
Genomic Location (Zv9):
Chromosome 12 (position 38065867)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 36012801
GRCz11 12 35707056
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCGAGATGACAGCGAGTCTGATGAAGAGGAAGACATCTTTGTGGAGAGG[C/T]GAGGAAGAAGCTGGTCTGCCAGCAATCCACCAAATACAAACCCAAGGACC
Long Flanking Sequence:
AAAGTGGTGCTTATGATTCTGACTCCAGCCCTGCTATGTCTTTAACTATGGAGCCTCTTTTGGGCCACGGTAGCCCCCTTAGAGCATGGGAATCAGGCCACTATGTCTCATACAAAGACAGGGATGGAGGTTATTACTTTGAACCATCACCTCCTAAGGTTATGGGCCGCTATATGATACGAGACTCAACAGAAACTCTACAAGAAAGCTGGGGCTCTCGAAGTCTGAGACAAGCACTTGGGGAACTGGAGGACCCTTTAGGCATCTCACCATCACTTGGAAGTCCTCCACAAGGCTATGCTGATCCTTATTTGGAGAGCATTCAAGGCTCCATTATAGGAAAGAATGTAACGGGTGGATACTATGATATGATGGGCTCTTTGAGAAAGACTATGCCAGGTGGCCACTCTGTTTGTACTGACATAGCATCAGGTGGTGCTGTATTTGTAGGTCGAGATGACAGCGAGTCTGATGAAGAGGAAGACATCTTTGTGGAGAGG[C/T]GAGGAAGAAGCTGGTCTGCCAGCAATCCACCAAATACAAACCCAAGGACCTTGCGTCAGAGGCAGGGGTCTTGTATCCAGGATTCCTATGCAGACTTCCACTACACTATGCCAATGACTGATATTGAGGATACATGGCCAGAGCAGCAGACCCTGTCATACCATATGACCAAACCTGTTGACTACTTGGAGGCACCGATTAAAAGCAATACTTGCTTGGTACATGGAAGACATGTACCTTCAAACCCTTCACCTGAGTGCAACTCATACATCCATATGTGCCACGAACCTAGAGAGGCTGAAGTATACCCTGTGCCATGTTGTCAAGCTTTGAGCAGTTCACATTTTGTAGACCCTTTAACAGGAACACTTGTGAGGAACTGCTTCATGATTGACTGTATTCCAGGGAAAACCATGACCTTGCCCAACAGAGACCAACATCTACCTTTATCTGCTGGACATATAATCTCCAAAATAGAAGCATCAAGGGAAGGAGCCAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11207
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111560 Nonsense 981 1657 11 14
Genomic Location (Zv9):
Chromosome 12 (position 38066425)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 36012243
GRCz11 12 35706498
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACATCTCGGAGCAATTTGTGGATAYTGCAGWAGGAGAAACAAACTTAAAA[C/T]AAGAAAAAACRTTGCATCAAGATATATCTACAGCAGATCCAAAAACTGAA
Long Flanking Sequence:
AGAGGCAGGGGTCTTGTATCCAGGATTCCTATGCAGACTTCCACTACACTATGCCAATGACTGATATTGAGGATACATGGCCAGAGCAGCAGACCCTGTCATACCATATGACCAAACCTGTTGACTACTTGGAGGCACCGATTAAAAGCAATACTTGCTTGGTACATGGAAGACATGTACCTTCAAACCCTTCACCTGAGTGCAACTCATACATCCATATGTGCCACGAACCTAGAGAGGCTGAAGTATACCCTGTGCCATGTTGTCAAGCTTTGAGCAGTTCACATTTTGTAGACCCTTTAACAGGAACACTTGTGAGGAACTGCTTCATGATTGACTGTATTCCAGGGAAAACCATGACCTTGCCCAACAGAGACCAACATCTACCTTTATCTGCTGGACATATAATCTCCAAAATAGAAGCATCAAGGGAAGGAGCCAAACAGTTTGACATCTCGGAGCAATTTGTGGATACTGCAGTAGGAGAAACAAACTTAAAA[C/T]AAGAAAAAACGTTGCATCAAGATATATCTACAGCAGATCCAAAAACTGAAATTATCGCCATATACCCACAGTTGGAAAAATCCCCAGCAGAATTATCCAAACCAGAACCAGAGTCTGAGCTGAGTAAGACTGCAGACAGTGGTATGGACCGTGGACACTCTAGTATCAGCCTGGTTGAGATAGATGACTGCAGTGATGATGACATCACTGACGTAACCTCAGGCATTTTTGGTGATTTTGCAATTGAAGTGGAAACTGTTGACTACCCCAGTCCAGCATTCAAGTCATTACAAAAACAAGTTGGTACTCCAGACTCCATGGACTCTATTGACATACCGTCTACTGCATGTTCCAGTGAGACTCTCAGTCCGGCTTCCATCCATCCATCAAGCTCTCCTAAGACTGTGGATAGTGGCTATGACACAGAAAACAATGAATCTCCAGAGTTTGTCTTAAAGGAACCTCATGAGGTACAAGATTCCAAGACTTTCATTCAACCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19043
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111560 Nonsense 1262 1657 11 14
Genomic Location (Zv9):
Chromosome 12 (position 38067268)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 36011400
GRCz11 12 35705655
KASP Assay ID:
2260-5686.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAAAGGAGACAGATGTAGATGAATATCTTATGCCATCTACAAAGAAGAGT[G/T]AAAAAATCCCTGAACTGTCTGATCATTCAATCTCAAACCTTCCATCAATG
Long Flanking Sequence:
CTGCATGTTCCAGTGAGACTCTCAGTCCGGCTTCCATCCATCCATCAAGCTCTCCTAAGACTGTGGATAGTGGCTATGACACAGAAAACAATGAATCTCCAGAGTTTGTCTTAAAGGAACCTCATGAGGTACAAGATTCCAAGACTTTCATTCAACCTTTGGGAAAGGTAACATCTGGGACAAGTTTTGTCAGTGAAGACCAAGAGATTACAACAACAGAATGTGAGAAGCTTGAGGGTGATTTTTATACTGCAGTGGCCTTGACAGCATCTGAGAGCAGTGATGGAGAGCTGAAAGCACTGAGTGATAAAACACCATACAGAGATTCTGCCTACTTTTCTGATTATGATGCTGGCAAAGATAAAGAAAGCGAAGAGGACATCAATGAACTTGAAGATCAGAAAGACAGACCAGGGGAAATTATATATAAAGAGGAACAACTTCCTCCACAAAAGGAGACAGATGTAGATGAATATCTTATGCCATCTACAAAGAAGAGT[G/T]AAAAAATCCCTGAACTGTCTGATCATTCAATCTCAAACCTTCCATCAATGACAGATGAAAGTTTGTCTGTGTGTGGCACAATCTGTAGCGTGTCTCTCTCACCTCTTAAAGACGTTTCTACCATAAAAAGTAGTTTTGAAGATAATGAAAATATTGGTGTTGTTTCAGATCTCTCTGCAGAACTTTTAGCATCTGAAGAACTTGGTACTGATGGAAAGCAAGAGGAATCTTTCAAACAAGTAGAAAGTGAAGATAGTCTGTCTCATGACCAAGTTACTTTTGAAGGCGATCTTGTAAACAAGCCCAATCCAGAGGTACTTACTGATGAGAACGAAGAGGACATAGTCAAAGATGTCAGCTGTGCCATTTTGTCCGAAGAGGAACTACAGTCTCAAAAGGAAAAAGCAGAAAAGAATGACTCTCCTACACATGAGGAGCTAAAATCCAAGAGTAAGGACTGTGAAGGAGAAGGACGGAAAAGAATCTCCGCACGATCTGGC
Associated Phenotype:
Not determined