ZMP

ENSDARG00000075964

Ensembl ID:

Human Orthologues:

ARHGEF40, PLEKHG4

Human Descriptions:

Rho guanine nucleotide exchange factor (GEF) 40 [Source:HGNC Symbol;Acc:25516]
pleckstrin homology domain containing, family G (with RhoGef domain) member 4 [Source:HGNC Symbol;Ac

Mouse Orthologues:

E130112L23Rik, Plekhg4

Mouse Descriptions:

RIKEN cDNA E130112L23 gene Gene [Source:MGI Symbol;Acc:MGI:2685515]
pleckstrin homology domain containing, family G (with RhoGef domain) member 4 Gene [Source:MGI Symbo

Alleles

There are 6 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa45284	Nonsense	Mutation detected in F1 DNA	Not yet available
sa7074	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa21000	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa45284

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000108473	Nonsense	875	2484	1	22

Genomic Location (Zv9):

Chromosome 7 (position 36179537)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	7	34453380
GRCz11	7	34724857

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AAATGTAATTAATACATCACAGCCAGAGACTGAAATGTTATCTTGTGTTT[T/A]GGAAAGGGAGAACTCAGAACAGGTTTCTCCAGCTTATATTGAACTCATTG

Long Flanking Sequence:

ATTAGACAGCAAACAAGAAAGTGTCTCTCAAACAGACAGCAAACCAGTCAGCATATCACCAGACAATGAGCCAGTGAAGACATCACAACCACAACTAGAAAGCACATTACACCCAAACAGCAAACAAGCAAGCATGTCACAACTAGTCAATGAACACATCCAGACCTCACAGCCAGACCTAAAACCAGTAAGCATTGCTCAACTCTACAGTGAAGATGCTAAACCAGATGGATACGCTGATGTCAAACCAATAACCACTGAGCTAGACAATGGACTAGTGAGCACATCACAACCAGATAACCAACCAGTTGACACACCACAAGCAGAATGTACAACAGTTAACATAACCTTACCAGAGGGCAACCCCAATGACACATCATATATTGTCAACCTGCCGCTAAGTACATCACAACCAAACAGCAAAACAGTTCATGTGGAGCAAGCAGACATAAATGTAATTAATACATCACAGCCAGAGACTGAAATGTTATCTTGTGTTT[T/A]GGAAAGGGAGAACTCAGAACAGGTTTCTCCAGCTTATATTGAACTCATTGTGTCAGATCCTTATGCAGAAGTCAGATGTGAATCTAAAGAGCTGAGAGTTAATTGTGATCTTGAAGGCAGTTGTGGTTCACAGAACAACAGAGCGTCACTTGCCGAGACAGTAGCTGAGAGTGTGTCTTCGCAAAATCAGATTGATCAAACAGGCAATAGCCTGTATCAGATACACAAACCCATCCATACACCATCTGAGCAAATGCATGATCTTCCTACCATAAAAGAAGACCATCAGACATTCAGTAGCAGTTCTCATAACACGAATGAATCTGTTGGTGATTTAAGTCCCATTGCAGAAGAAGATGGTGGGTCTGTTACAGCTGCTCTGTATAGTGAGCATGTAGCCTTAGTTTCTGTCACCACAGTGCCTGGGGAGAGTCCAGTTACACTCATTTCACAGGGTCAGGTGGGGACAGAGTCTCCTGAGGACAGAATCAACCAGACAG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa7074

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000108473	Essential Splice Site	1372	2484	4	22

Genomic Location (Zv9):

Chromosome 7 (position 36185731)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	7	34459574
GRCz11	7	34731051

KASP Assay ID:

554-4819.1 (used for ordering genotyping assays)

KASP Sequence:

CAGGTGTTCACCTGTTCCCGCCCTTTTCAAAGCCTTYAACATCCTCCAGG[T/C]AAGAACACCCTGAMAGTATGATTTGYAATAACAAACACGCATGCAGTGTA

Long Flanking Sequence:

TCAGAAATCATTCCAATATTATTATTATATTTTATAAAATTATTTTCAATGTTAAATAATTACCTGATAGTTTTGTGAAAATTTATCCATTTTTTCAGGATTTTTTAAATTAACATTTTAAATGTTAATATAAACATGTATTCAATCTGATATTACAAGTGGCTTTACAGTCAGGTTTGATCTGTTCAGTTCAATTTATGAATGAATAAAATATTTAATTTATATTGTAAATGGGAATTTTCACTTCAAACATTTGAATGATATGTGTTTTCTCTGTGATTTATTAGACAACATACTTTTCTAAATATGTATTTATCTACCTGTTGCTAAGGGAAAACAAGCAAGTGTGTATGAGATTTGTTTACCTGTATTTCACTAAAAATGTGACCTGGATTTGACACACAGGAAGGAAGTAAGTGCTTTGGGATTGACTGTCCTGGTGGATGCCCGCAGGTGTTCACCTGTTCCCGCCCTTTTCAAAGCCTTCAACATCCTCCAGG[T/C]AAGAACACCCTGAAAGTATGATTTGCAATAACAAACACGCATGCAGTGTACCATTCATTAATATCCTTCAGAGAATCTCACACGAATAGACACTGTCACACAATGTTCACATGCTCAAGGCGTTTCCTCTCTCATACTTGCTTCAAAACTGAATGGAATGCAAGCGTGCCATAAATCCTGATCTTTAAATCCAACTTCCAATCAGACATCTGCTACTAGGGAGTTCACAAGACAACTTTGCAAACCATATCAAACCTTTGAGAAGAGTTTACATCATCAAAATCAATCGTTAATGGCTAAACAGGACAAATATAAACAACACATCATAAATATTAACCGTGATGTACCAGCTGTGGAAATAAATAGGCTGCATTCCACACAGTTATACAACAGGAGATACACACGCAAGAGTCAGAGAGAGAGCACATGACTTCCCATCTGGGATTGATTATTTTGCAGAAAGCTTCTGATATAAAATGGTTTGTAGTCAGTAGTTATTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa21000

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > G

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000108473	Nonsense	1430	2484	6	22

Genomic Location (Zv9):

Chromosome 7 (position 36191711)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	7	34465554
GRCz11	7	34737031

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CATGTGGACGTTTCTCAGCTTCCCACTGAGTTTGAAGGCACTTTCCCTTA[T/G]GCACACAGCAGCTGGGTCAGCTTTAGAATGGTGAGAAAATCACAATCTTG

Long Flanking Sequence:

AATGATAACTGCCAGCTTTGATCTTCAGGTTTTAGAGAACAATGTCAGTTTACTGAGAGTTTCTAGTTAGTGTCAAAGTAAACAAGTAACATCCTCTAATAACATGTGTTTGAATAGGATTGTTTCAGAATATAGTGACATCCTTTCAGAAACAAACAGCATCCAACAACACACACAAGGCTATTTTTACATAAGTGTCTGGACTAACATGCCACTTATGCCTGACAAATAGAGATAGAGTGTGTAAGAGACAGTTGAGAATGTCACAACAACAGGACAGATAATTTACCCTAGGCATCTATCTATGCTATTAGAACAGCCATTGCAGCATGTAAAGTGTTTATGATAGCACTGTTATACATGTTTGTCCCCATTGAGACCTAAAGAGTGTTGTTTTCTCTTGCTATCTGTCAGGTGGAGCTGCTGACATCACTCAAGTCTCTCTATAAACATGTGGACGTTTCTCAGCTTCCCACTGAGTTTGAAGGCACTTTCCCTTA[T/G]GCACACAGCAGCTGGGTCAGCTTTAGAATGGTGAGAAAATCACAATCTTGAATAGTACAGAAAGCTGGAATACCAATGTTTTGGCACAGATTTTGTACCCTGATTTGCAGTCTAGAATTTAGATTTTAAAGAAAAAATGTTAATTACATATTCCTTATCTTTAATGTAATTTATTTTTAATTTGTAATGTTTTTTATTTCAAATATTTACATAAACCCCTTAGCACACCCATGGGGCAGACCCCAGACCCAGTCTAAAAATCCCTGGTTTGATGTATGATGCCTACATTTTCTGTAATCTTTATAGACTACTTAGAGGGATGTAAACAAAAACATGGTCCCAACGTATTTCCTACTTTACATTTTTGATTTATATAGCTTCAGAGAATCCAAAAAGAGCCACATATTGATAAGTAATGCTATGACGGCTGTTTTAACATCAAGTTATGATCGAATTACCTCTTGTTACAGATATGAAATAGTTTGATAATAAGCAGGAAA

Associated Phenotype:

Not determined