ZMP
zgc:152897
Ensembl ID:
ZFIN ID:
Description:
poly [Source:RefSeq peptide;Acc:NP_001070643]
Human Orthologue:
PARP8
Human Description:
poly (ADP-ribose) polymerase family, member 8 [Source:HGNC Symbol;Acc:26124]
Mouse Orthologue:
Parp8
Mouse Description:
poly (ADP-ribose) polymerase family, member 8 Gene [Source:MGI Symbol;Acc:MGI:1098713]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa20501 | Essential Splice Site | Available for shipment | Available now |
| sa45220 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa40522 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa20501
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000083467 | Essential Splice Site | 220 | 859 | 9 | 26 |
| ENSDART00000133183 | Essential Splice Site | 220 | 861 | 9 | 26 |
Genomic Location (Zv9):
Chromosome 5 (position 42502147)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 40276864 |
| GRCz11 | 5 | 40877017 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTTATTGTACGGCTTCACTGCTCCCTCACACAATATCTGAATGGACCAG[G/T]TTAGATGCACACAGACACAAGCAAACTTTCTGTAATACAAGATTTATCTT
Long Flanking Sequence:
GAATGGGTGTTGTTCAATAGTTTTATGACAACTTTTATTGTATGGTTTTTATCCACTACTATATGTACTAATATTACACTTGAATAAATTTCTTTTTTTAGAAGGAAAGTACATTTTAGAAAAGTACATAAAAAGTTTTTGCCTATGCTTTAGCTTTTAAAAGATGTATAATAATAATTAACATGACTAAACTTCTTTTTCTGAAATGATATCATAATGTTAGGAAATCTGTTTCTTTTTGCTTAATGTAGGGAATATGGTGCAATTGATGACGTGGACATCGACCTACACATCGATGTCACTTTCTTAGATGTGAGTGTTACTGTTCAGTGTCACGAATAGTGATGAGCATTGTTTTTTTATGTGTGTATTATATTGTGTGAAACTAAAATGAATCATTTGTTTAAAGGAGGAGATTGCACTTGCCTGGGATGTGATCCGGAGTGAACCTGTTATTGTACGGCTTCACTGCTCCCTCACACAATATCTGAATGGACCAG[G/T]TTAGATGCACACAGACACAAGCAAACTTTCTGTAATACAAGATTTATCTTCTGAATGACTACATTTGAAGACCTGAACTGGATGTTTTTGCATGTTAAATTTATCTATGTTACCTATAAAACCAAAATTATGATTTAAAGGGGACCTATTACGGCTGTTATGACAAGATGTAAAATAAGTTGTTGATGTCACTAGAGTGCGTATGTGAAGTTTCAGCTCAAAATACCCAACAAATAAATTTTAAGAACTTTTTAAAACTTCCCCTTTTAGGATTTGATCCAAATTGTGTTGTTTTGGTGACTGCTGCTTTAAATTCAGTTCAGAGACGTCTCTACTGAGTGCTCTCACTGCTCACAAAGTTTCGGCGCCATGTTCTTTTCTCAGGTAACGGTTTGTCGTTGTTTTCTTTCGTCTTGTTCTTCTCCTCGCTTATTTTTGGTTTTACAAACACATTGCTAGGTTTCGTTTTAAAATTGTCTGGCTCAATTAAATTGGTAAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa45220
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000083467 | Nonsense | 269 | 859 | 11 | 26 |
| ENSDART00000133183 | Nonsense | 269 | 861 | 11 | 26 |
Genomic Location (Zv9):
Chromosome 5 (position 42494131)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 40268848 |
| GRCz11 | 5 | 40869001 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTGGAAGTGTCAGAGCAAAGATAAACTCATCAGCCCGCACAGCAAAAAG[C/T]AAACAGAGAAGAAAGTCAAGTCTCCCCTGCATATTTTTTCAACATTACGC
Long Flanking Sequence:
CTCAAAATTACTTTCCTCAAGAACATGGCCTCTTCAGTTCAGATTACAAGGGAGAGAGGGAGAAGTCACTTATAGACATGGCCATAATGTCTGCTCTTGTTCTCCTGCCAAGAAATTGCTCATCATAAGTGGCTCATTTCAAATTGACCTTCTGTTCCTGTGTTTTGAAAACCCCTGAAATGTGTTGATGTCTAAATCAAATGTCTATAGCTACTTTATGTGGAACTGTGTTTTGCAATACTTTTCTCTCATGGATAATTTCGTGTCCTCTTTTCAGTTCCCACTGTTGATGTGTTTCAAGTGTCTACAAAGGACAGATTTGGACTCGGACATCAGTTGAAAAAGTAAGACACTACAGGGAAATGTTTTCTAGTGTTATACAGGCTTTTCGGGTGTCATTCATGAGCGTGTTATCTCTTGGCAGGATAATGCAAACCTTTGTCACACAGCAGTGGAAGTGTCAGAGCAAAGATAAACTCATCAGCCCGCACAGCAAAAAG[C/T]AAACAGAGAAGAAAGTCAAGTCTCCCCTGCATATTTTTTCAACATTACGCAGGTAAAAAAATATATTTCCACCACACCAATTTTAGACAAATAATGTATACAACATCCCCCTTTTAAGCCCTTTATATACGAGCGTAAAAAAGCTTGTTTAGAGTTGATATAACCCTTGATTCAGTTTAAGATGACAAGCACTGGGTTGAACTGGGCTTGAGTAAGTATAGGATAATGTACATCTAGCTAGTTGTAAGTCACAGAATAAAGCCAGACAGGTTTATTAGAAGCTCAATGTGAAGACTGAAGGGCTTTATTCTGTGAAAACAAACGACTAGATCAAGGATGGTCAAACTTAATTCTGGAGGGCTGGTGTTCTGCCAGTAGCTTTCTAGTAGAAACTCTACAGGACACTGGCCCTTGAGGATTAAGTTTGCCCATCCCTAAACTGGATGTACATGATCCTACTTAAAGTTGAAGTCAGAATTGTTAGCCCCCATTTGATTTAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40522
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000083467 | Essential Splice Site | 603 | 859 | 16 | 26 |
| ENSDART00000133183 | Essential Splice Site | 603 | 861 | 16 | 26 |
Genomic Location (Zv9):
Chromosome 5 (position 42484576)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 40259293 |
| GRCz11 | 5 | 40859446 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCTGTGGTGGATCCCAATGACTCACAAGCACTTGCCTTCAACCCCAGGG[T/A]ACTCAAAACTCTAAGAGCATTCCATTCAACCTGTCTAACGTTTAATGCTG
Long Flanking Sequence:
TGTTTTCGCCTTCCAAACGCTAGGGGTCATGAATGAGGCTGCTGATGAGATTGCCACTGGTGCTCAGGTATAAATAAACACACAAATTCAAGCACAACAAAAAAGTGGAAAACTGATGTAATGGATGCACTCAGACATTCTTTACCAGAGTATATGTAGTCAAATCTCCTTCTTTTTGTTTCTTATTGTACATATTGTAGTTTTTTAAATTGATATGAAAGTGCTACAACATAATAATAGACATAATATTTATCCTGTCCCAATCAATTGTGGCTTAACCAAAAGTTTAACAAATGGCCCACGGGACGGCAGTTTGAGAACCCTGGTCTACAGAATAACCAAATGCCTTAACAAACCCTATTTGTATGCACAGGTAGTAGATCTACTAGTCTCCATGTGCCGATCTGCGCTGGAGTCTCCGAGGAAAGTTGTCATTTTTGAGCCATATCCCTCTGTGGTGGATCCCAATGACTCACAAGCACTTGCCTTCAACCCCAGGG[T/A]ACTCAAAACTCTAAGAGCATTCCATTCAACCTGTCTAACGTTTAATGCTGCCATTAAGGAAGAATGTTACACTGATTGTTTGGGTTCTTCTTCAGAAAAAGGACTATGACCGGGTGATGAGAGCACTTGACAGCATCACATCTATCAGAGAAATGACCCAGGTATCAACTAGTTTATTGCAGTAGCAACCTTTTGATACATTGTTTCAGTGCTTTCAATCTTTTAATATTGATAAATTTTAGTGGGATTAAAATATACATTATAGTATGTGTAATATCTTATAAGTAGTAGATTTAAAAAATATATGTTCAAATAACATTTGATTAAACATATAAATCAACAAGTCCTTGTTTAAATTATAACCGTATACTATGGTCAGTGGTCTAATTGTAAAAAAAAATTCAAGGTGGATGGTACGGGGGGTGGGGTTGGGTGGTGTCCAGTAGCTACACACACACACACACACACACACACACACACACACACACACACACACACAC
Associated Phenotype:
Not determined