ZMP

si:ch211-149p5.1

Ensembl ID:

ENSDARG00000076044

ZFIN ID:

ZDB-GENE-070705-41

Description:

Novel protein similar to vertebrate thyrotropin-releasing hormone degrading ectoenzyme (TRHDE) [Sour

Human Orthologue:

TRHDE

Human Description:

thyrotropin-releasing hormone degrading enzyme [Source:HGNC Symbol;Acc:30748]

Mouse Orthologue:

Trhde

Mouse Description:

TRH-degrading enzyme Gene [Source:MGI Symbol;Acc:MGI:2384311]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa45176	Nonsense	Mutation detected in F1 DNA	Not yet available
sa40298	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa45176

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000112301	Nonsense	332	994	3	19
ENSDART00000133056	Nonsense	332	947	3	18

Genomic Location (Zv9):

Chromosome 4 (position 22178548)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	23521883
GRCz11	4	23242858

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CTGTTGTGTTGTTGTTGTAGATTCGGCTGTACGCCAGACCTGATGCCATC[C/T]AGAGCGGATCGGGTGACTACGCTCTGCGCATCACCAAGAGACTCCTGCAG

Long Flanking Sequence:

ATATTATTTGATTTGCTAAAGATCATGAGACACAAATGAATGGAGTTATGGTGGTAAAAATAACATACATAAGTTGCAAAAAAATAAATAAATATAGATATTTAAACCATATATTTATAAATATTTAACCAGTGGTAAAAGCAACTTTTCTTACTTTTCTGGTGAATCTTTTTTTTAAGATTTATGGGTAGCAGTTCTTCATAATTCAATAATAACATTGCAATCATGGTTGCCCTGCTTAAAAAAAAAAAGGTTCTTGGGTGAAAATTACTGATTTTTAATTTTGTGGCACTCTAGTTTTGAATGTTTTGCATAATAGATGGCGGATGCACTTGAAAGATGAATGAAATATTCAGCCAGATGAAGGCGTTTGGTAGATAAATTCACCATGGCTTACTCTACATTTCTCCTCAAGGGAGACGAATAAGAGTCCATTTTGACTTCTGTTTTCTGTTGTGTTGTTGTTGTAGATTCGGCTGTACGCCAGACCTGATGCCATC[C/T]AGAGCGGATCGGGTGACTACGCTCTGCGCATCACCAAGAGACTCCTGCAGTTTTACCAGGATTACTTCAAAGTCAAATATTCCCTCCCCAAATTAGGTAAGCCGGCCGGTGAAATGTCTTCATCTTTATCTGGCTTCAGTGACGCTGCTGAAACTGGTGATAAATGTTCTTCTCATCAGATTTTTCATTGTTCCTTCTGTCGGTTCTGTGTGAATTCATGTTTCGTTTTGGTGTAAAGAAGTGAAGAGTGTCGATATCAACACAGTTCTTGAGTTTATTGATCCTCAAAGTGCTGCAGGCGTGTGCGCCTGTGTTTGGTCTTGGGAATCAGAGCACGCACCTTGCGTGTGTTGTGAAAGTGTGTGTTTGTGGCTGTATTGACTTGTGTGTGTGCTGTATGTAGTTGTAAGTGTGAGTGTGTTTGTTCTGGACGACTCGTTTCGCTCCATTGGGTTCCTGTCAGCTCTCTGTATTCATTTGAATGTAGGCATCAATCTCTC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa40298

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000112301	Essential Splice Site	364	994	3	19
ENSDART00000133056	Essential Splice Site	364	947	3	18

Genomic Location (Zv9):

Chromosome 4 (position 22178646)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	23521981
GRCz11	4	23242956

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CAGTTTTACCAGGATTACTTCAAAGTCAAATATTCCCTCCCCAAATTAGG[T/C]AAGCCGGCCGGTGAAATGTCTTCATCTTTATCTGGCTTCAGTGACGCTGC

Long Flanking Sequence:

TATTTAAACCATATATTTATAAATATTTAACCAGTGGTAAAAGCAACTTTTCTTACTTTTCTGGTGAATCTTTTTTTTAAGATTTATGGGTAGCAGTTCTTCATAATTCAATAATAACATTGCAATCATGGTTGCCCTGCTTAAAAAAAAAAAGGTTCTTGGGTGAAAATTACTGATTTTTAATTTTGTGGCACTCTAGTTTTGAATGTTTTGCATAATAGATGGCGGATGCACTTGAAAGATGAATGAAATATTCAGCCAGATGAAGGCGTTTGGTAGATAAATTCACCATGGCTTACTCTACATTTCTCCTCAAGGGAGACGAATAAGAGTCCATTTTGACTTCTGTTTTCTGTTGTGTTGTTGTTGTAGATTCGGCTGTACGCCAGACCTGATGCCATCCAGAGCGGATCGGGTGACTACGCTCTGCGCATCACCAAGAGACTCCTGCAGTTTTACCAGGATTACTTCAAAGTCAAATATTCCCTCCCCAAATTAGG[T/C]AAGCCGGCCGGTGAAATGTCTTCATCTTTATCTGGCTTCAGTGACGCTGCTGAAACTGGTGATAAATGTTCTTCTCATCAGATTTTTCATTGTTCCTTCTGTCGGTTCTGTGTGAATTCATGTTTCGTTTTGGTGTAAAGAAGTGAAGAGTGTCGATATCAACACAGTTCTTGAGTTTATTGATCCTCAAAGTGCTGCAGGCGTGTGCGCCTGTGTTTGGTCTTGGGAATCAGAGCACGCACCTTGCGTGTGTTGTGAAAGTGTGTGTTTGTGGCTGTATTGACTTGTGTGTGTGCTGTATGTAGTTGTAAGTGTGAGTGTGTTTGTTCTGGACGACTCGTTTCGCTCCATTGGGTTCCTGTCAGCTCTCTGTATTCATTTGAATGTAGGCATCAATCTCTCTGGGCTTCTGTCTGTCGCTCTTCTGCCGTCTGCTCACTCATCTCCAAATGTGTGTGTGTGTGTGTTTCAGCAGGCATGTAATATTAATCATGTGCTTT

Associated Phenotype:

Not determined