ZMP
ENSDARG00000052950
Ensembl ID:
Human Orthologues:
AC140658.1, AC142086.3, AC142381.2, ARHGAP23
Human Descriptions:
Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:29293]
Uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:A8MTI0]
Uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:A8MTI0]
Mouse Orthologue:
Arhgap23
Mouse Description:
Rho GTPase activating protein 23 Gene [Source:MGI Symbol;Acc:MGI:3697726]
Alleles
There are 8 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa45148 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa2101 | Essential Splice Site | F2 line generated | Not yet available |
| sa20091 | Essential Splice Site | Available for shipment | Available now |
| sa33260 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa45147 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa5730 | Essential Splice Site | F2 line generated | Not yet available |
Mutation Details
Allele Name:
sa45148
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000074883 | Essential Splice Site | 346 | 1377 | 8 | 31 |
Genomic Location (Zv9):
Chromosome 3 (position 39343638)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 39206998 |
| GRCz11 | 3 | 39348856 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCTAGCAAGCCGGTACGGACACTCGGGACGCTCACTGGAAAATCTCGAC[A/C]GAGCTGTGGGGATACTCTCACCAAGGGTTGAAAGATCTGCTTGGGTTCAA
Long Flanking Sequence:
GTCATCTTGCCAATCACAACATGGGTACTGCCATGGGGCACACTGGAGGTCGTAAGGGAAGCCCACCTTGGGCCAGCCCTTCTCAGCCAACATCAACACCTTCATCCAGCCGCAACGAACGAACCCAACAAGCCCTTTCCAACTGGTACTACAGCCAGGTCCCAGGCCGTGAGCGAGAACGAGAACGAGAGCGGGAGCGATCTAGTTCTCGCTCAATGCACCCACGCCACAGGAGTTTCTCACAAGACCGTCTGGGAGAGCTTGGGAAGGCCAGGCGTTCTCAACAAGCAGGTTTTCCCCATAGTGCATCGCAAGACACGTTGCTGCTGCTTCAGCAGAGTGCTGCAGCATATGCTGATCCTTACTGGAACCATGGAGACTGGCGGGGTGAGCATATGTATGGTCAGCACCCATCTGTGGTGGCCTATGGGCGAAAGTCCTCCGAAAATCTTCTAGCAAGCCGGTACGGACACTCGGGACGCTCACTGGAAAATCTCGAC[A/C]GAGCTGTGGGGATACTCTCACCAAGGGTTGAAAGATCTGCTTGGGTTCAACAACCTCCAAATAGGACTGAAGTCTATGCAAGACATGCTGGGCATTTCGGCCAACATATAGAGTCACCCCACCAAATGCACCACACACCCCAACACCACCAGAATCTCACACATGCAACACACCAACACTCATCTCAAATCCCACAACCTCAGCAGGCAGCTCCAATGGCAAGACGTTTGCCTTCTTGCCAGAGTCTAGATGAGGAGCCGATTGGCTATCGTAGCTACAGTCCCTCATTCAATAGGAAGACTGGCCGTATCTTGCAGCAGGCCCAGTCATTTAGAGATCCCTCTTACACAGGTCCACACCTTTGGACTCCAACATCCAAAACCAGTCCCCCAGAGGGGCATCCACCCTCAGCCACTGCTTCCCCAGCCCCACCAACCACTTCCTCTTCAACTACGATTTCCACACCATCTGAAGGACAAGACAGAACTTACCGACCCACT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa2101
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000074883 | Essential Splice Site | 369 | 1377 | 8 | 31 |
Genomic Location (Zv9):
Chromosome 3 (position 39343566)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 39206926 |
| GRCz11 | 3 | 39348784 |
KASP Assay ID:
554-2819.1 (used for ordering genotyping assays)
KASP Sequence:
CAAGGGTTGAAAGATCTGCTTGGGTTCAACAACCTCCAAATAGGACTGAA[G/A]TCTATGCAAGACATGCTGGGCATTTCGGCCAACATATAGAGTCACCCCAC
Long Flanking Sequence:
CCAGCCCTTCTCAGCCAACATCAACACCTTCATCCAGCCGCAACGAACGAACCCAACAAGCCCTTTCCAACTGGTACTACAGCCAGGTCCCAGGCCGTGAGCGAGAACGAGAACGAGAGCGGGAGCGATCTAGTTCTCGCTCAATGCACCCACGCCACAGGAGTTTCTCACAAGACCGTCTGGGAGAGCTTGGGAAGGCCAGGCGTTCTCAACAAGCAGGTTTTCCCCATAGTGCATCGCAAGACACGTTGCTGCTGCTTCAGCAGAGTGCTGCAGCATATGCTGATCCTTACTGGAACCATGGAGACTGGCGGGGTGAGCATATGTATGGTCAGCACCCATCTGTGGTGGCCTATGGGCGAAAGTCCTCCGAAAATCTTCTAGCAAGCCGGTACGGACACTCGGGACGCTCACTGGAAAATCTCGACAGAGCTGTGGGGATACTCTCACCAAGGGTTGAAAGATCTGCTTGGGTTCAACAACCTCCAAATAGGACTGAA[G/A]TCTATGCAAGACATGCTGGGCATTTCGGCCAACATATAGAGTCACCCCACCAAATGCACCACACACCCCAACACCACCAGAATCTCACACATGCAACACACCAACACTCATCTCAAATCCCACAACCTCAGCAGGCAGCTCCAATGGCAAGACGTTTGCCTTCTTGCCAGAGTCTAGATGAGGAGCCGATTGGCTATCGTAGCTACAGTCCCTCATTCAATAGGAAGACTGGCCGTATCTTGCAGCAGGCCCAGTCATTTAGAGATCCCTCTTACACAGGTCCACACCTTTGGACTCCAACATCCAAAACCAGTCCCCCAGAGGGGCATCCACCCTCAGCCACTGCTTCCCCAGCCCCACCAACCACTTCCTCTTCAACTACGATTTCCACACCATCTGAAGGACAAGACAGAACTTACCGACCCACTAATCATGACAGAGGGGCAGGGGAAGCGACAAGTGAAGCCCAGACACAGGAAGTGGTTCTGAGGCAGAAACCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20091
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000074883 | Essential Splice Site | 631 | 1377 | 12 | 31 |
Genomic Location (Zv9):
Chromosome 3 (position 39330128)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 39193488 |
| GRCz11 | 3 | 39335346 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATGTGATGAGGGGCTTAACGCATATAGAGAAGAGGGCCGGGTCTTCTCG[T/C]GAGTTTTGGGATTTTTTACTATACTGTTATGATTTGCACTATAATGCAAA
Long Flanking Sequence:
GCTGTAAAATAACATTTAAAATAGCATATAAGGGGCACTTTAAGAAATTTAGTTAAAAATTGTTGCATGTGATCGACGTAGAGCTCCCCCTACTGCATGCGTATTCGTACTGCACAAAACAGTCAAATGTGAATGTGCATGCTGCATCTCATATAGATCCACAATGATCGTTTGGTAATGCCTGTGCATCATCTTTACTGAGACTGTGATGAAGATCATCTCCCTCCCACCTCCTAATCTCAGATACTCCCCACTCAACTCCACACTAACTGTCCTTCACCAGATCTCTCGTTCTCTCTCTTCTCCTATACTCTGTATTCCTTTTTCACTGAATTTAATGAATGGATGTCTCTCTCTCTCTCTCCCTCTCTCTCTCCCCATGAGCAGGTGATCCTAAATCTAATCGTCGCTCCTCGTACCTGTTGGCCATCACCACTGAACGCTCCAAGTCATGTGATGAGGGGCTTAACGCATATAGAGAAGAGGGCCGGGTCTTCTCG[T/C]GAGTTTTGGGATTTTTTACTATACTGTTATGATTTGCACTATAATGCAAACAACATCAGGAAGGGCATTTTTGAGATATTTAGATGTCAGTCAGTGTTTATGCTTTAACATATTCCTGTTGTGCTTGTTTAACAGGAGGCTTCCAAAAAGAGTCAAGAGCTTCTTTACTGAAGGGGTGAGTTTACTACAGTAGAAACTGTCATACACTCTCATACTCTGACACAGAGCAGAATTTCGTAATCTTGTTAACGTAAATACTGTATTTCCAGCTCAAGCTTTTAGTAATTTGTAACTTTTGATTTAGTTGTTAATTTATATAACTGTATATGATCTCATTCATACATTTTAGTGCAATTTTCTTACTCAGAACCTCCAAACTCGTGTTGTTATATCTTTTCCAACTGATTCGACTTACGGTTTTTCAAAAAGTGACTCGGAAAATTCAGAAAATTCCCATTGACTTTACATTGGACCAAACTTTAGGAGCTCATAACTTTGCG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa33260
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000074883 | Nonsense | 982 | 1377 | 20 | 31 |
Genomic Location (Zv9):
Chromosome 3 (position 39318845)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 39182205 |
| GRCz11 | 3 | 39324063 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATTTCCTCCTGAAGATAAATATAATGACTTTATCGACGCCAATCGGATG[G/T]AGAACGCCAGCGATAGGCTGAGGACAATGAAGAAATTGGTATGAACTTGT
Long Flanking Sequence:
TTTCCTTCACTCGTTATTCTCTTATGTGGTACTTCAAAATGTCCATTAAAACAATTCAATAGAAACCTAGCTACTGTTACATTTCTATGAGCTTTTTGACAACAAGTCAACATTCTGGTTATATTCACTTCTCTTGTTTCAGATGATACTTCCTCCTCCTACTGAGTATCCTCTGTTGTTTAAAAACTGCTTTTGTTTTTATGCTCCTGTACAGAAATGGCAGGACCTGAATGTGGTGAGCAGCCTGCTGAAGTCCTTCTTTCGTAAACTCCCTGAACCCCTCTTCACTGATGGTGAGATCAGGAGCATTCTAGCTGTGATCTTAGTGCTGCTTTATATTAATATAACTAGTAAATGAATGGAAATTTATTAAATGTTTTGAAAAGTTTGCAAGGTGTGAAGTACCCTTTGACATGAAGTGAATTTTTCCTCCTTTTATTTCCCTTCCTTTATTTCCTCCTGAAGATAAATATAATGACTTTATCGACGCCAATCGGATG[G/T]AGAACGCCAGCGATAGGCTGAGGACAATGAAGAAATTGGTATGAACTTGTTTTCAGCATGTTCGTAATTGAAAGAAAATCAATTATAGTCTAAACTTTTTTGATTACCCTAGTCTTCAGTGTCATGTCATCCTTCAGAAATTAATCAAATATGAGTATTTGTTCCACAAGAAACACTATTAACATTATGATCAACAACAAAGCTATTCTATGCTATAAATATATTTGCATAAATGGCACTTTTGATTAAATTATTGCATTGTCTTCTCTTTATTCCTGCAGATTCGGGACCTACCAGATCATTACTTTCACACTCTGAAATTTTTAGTTGGACACCTAAAGACGGTGGCTGACCACTCTGAGAAAAACAAAGTGAGCAATGCTTGATTTTCTGTGATTCTGTGAAAATTATTTAATTTAATTTAATTATTAATTTAATTATTCAATTCGCCCATTTTTCTTTTTAAACAAAATAAATATAAAATTTTTACCATACAAGGC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa45147
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000074883 | Essential Splice Site | 994 | 1377 | 20 | 31 |
Genomic Location (Zv9):
Chromosome 3 (position 39318805)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 39182165 |
| GRCz11 | 3 | 39324023 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAATCGGATGGAGAACGCCAGCGATAGGCTGAGGACAATGAAGAAATTGG[T/A]ATGAACTTGTTTTCAGCATGTTCGTAATTGAAAGAAAATCAATTATAGTC
Long Flanking Sequence:
GTCCATTAAAACAATTCAATAGAAACCTAGCTACTGTTACATTTCTATGAGCTTTTTGACAACAAGTCAACATTCTGGTTATATTCACTTCTCTTGTTTCAGATGATACTTCCTCCTCCTACTGAGTATCCTCTGTTGTTTAAAAACTGCTTTTGTTTTTATGCTCCTGTACAGAAATGGCAGGACCTGAATGTGGTGAGCAGCCTGCTGAAGTCCTTCTTTCGTAAACTCCCTGAACCCCTCTTCACTGATGGTGAGATCAGGAGCATTCTAGCTGTGATCTTAGTGCTGCTTTATATTAATATAACTAGTAAATGAATGGAAATTTATTAAATGTTTTGAAAAGTTTGCAAGGTGTGAAGTACCCTTTGACATGAAGTGAATTTTTCCTCCTTTTATTTCCCTTCCTTTATTTCCTCCTGAAGATAAATATAATGACTTTATCGACGCCAATCGGATGGAGAACGCCAGCGATAGGCTGAGGACAATGAAGAAATTGG[T/A]ATGAACTTGTTTTCAGCATGTTCGTAATTGAAAGAAAATCAATTATAGTCTAAACTTTTTTGATTACCCTAGTCTTCAGTGTCATGTCATCCTTCAGAAATTAATCAAATATGAGTATTTGTTCCACAAGAAACACTATTAACATTATGATCAACAACAAAGCTATTCTATGCTATAAATATATTTGCATAAATGGCACTTTTGATTAAATTATTGCATTGTCTTCTCTTTATTCCTGCAGATTCGGGACCTACCAGATCATTACTTTCACACTCTGAAATTTTTAGTTGGACACCTAAAGACGGTGGCTGACCACTCTGAGAAAAACAAAGTGAGCAATGCTTGATTTTCTGTGATTCTGTGAAAATTATTTAATTTAATTTAATTATTAATTTAATTATTCAATTCGCCCATTTTTCTTTTTAAACAAAATAAATATAAAATTTTTACCATACAAGGCGTAATGTAACACTTAAGTAATTTACTTGGGTTAAGATTTG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa5730
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000074883 | Essential Splice Site | 1310 | 1377 | 30 | 31 |
Genomic Location (Zv9):
Chromosome 3 (position 39311475)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 39174835 |
| GRCz11 | 3 | 39316693 |
KASP Assay ID:
554-3488.1 (used for ordering genotyping assays)
KASP Sequence:
CTTTCCGAACTCTCGAGCTCCTCCGCCGCAGAGGAGGAYCGCCAGTCAGG[T/C]GCCAATCAAATCCCTGACTCCTCTCCGTCTCCTTCTTCAAAAGCCAAAGG
Long Flanking Sequence:
ACTCTGTCCACTTTGGGGCGGAGCTTAGCTTCAGAGGGGCGGGGCGAGGATGCAGATGATGAGCATAGTGAACTAGTGAGTGAAACTGATAATGAAAGCGGGTTTGCCTCACGCTCCCTCACCCAAGAAAGGCCAGAAAAACCAAACCGTTCCAACCAGAACTCTCATGCGTCTCCTGAACCAACCGCACCACAGAGTTTCCTCTATGCGCACTGCAAATCACCTACACCCTCTGGCTCCGCCACTGCTCCATCTCCCCCTTCACAACACATCACAACCAACCCAGAGGACAGCGCAGCACGCTCGTCTACTCCCTCAACCTCCTCTTACTCCTCATCCGCCTCACAACGGCTCCACAACCGCTCTTTCAACTCCCACCGCCTCATACAGTGCGACACCCTTGCACGCCGTCGGACAAAGGCGGACAAAGCCAAAGCTCCCTCAGTGGACCTTTCCGAACTCTCGAGCTCCTCCGCCGCAGAGGAGGACCGCCAGTCAGG[T/C]GCCAATCAAATCCCTGACTCCTCTCCGTCTCCTTCTTCAAAAGCCAAAGGGTTTAGCATAAGAAACGAGTGTACGCCAATATCCATGGTTGGTCCCGGAAGTAAGGGGTGTGTGTTGTCCCCCGGGCAAGGATCCCTGGCGGATCAGGTACGTGCTCGTCTAATGGGCTCGGCGGATGACCTGTGCAGCGTTGGCCTGAGAAAGCAGCTCTCGCCGGAGACGCGCCGGAAGAGACGCGCTTGGAGGAGACACACAGTGGTCGTGTCCCCTACGGATTGTTCAGACAAAAAGCCAACGGTCCAAAGCACCAAACCTCTAGCTTCACCCTCCCCTGTTGAAAAGCAGGATGTCAGAGAGTCCCACCCAGAGTGCTCAGAAACTGAAGCCCCTACTGCACGTCGGGCCGTGCCTACCTCGCGCTTTCGTGATTTCTTGTAGCAGTGGTGGTGTGTACAGGCTAGTGAACCAAGAGAGTTGGATTTGGGTTGTGTTGTAGCTGC
Associated Phenotype:
Not determined