Busch Lab

ZMP

zgc:165453

Ensembl ID:
ENSDARG00000078183
ZFIN ID:
ZDB-GENE-070720-13
Human Orthologue:
A2ML1
Human Description:
alpha-2-macroglobulin-like 1 [Source:HGNC Symbol;Acc:23336]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa45126 Nonsense Mutation detected in F1 DNA Not yet available
sa39972 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa39973 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa45126
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024900 Nonsense 152 1456 3 34
Genomic Location (Zv9):
Chromosome 3 (position 3988468)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 3672867
GRCz11 3 3455120
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCAGGTCTTACCTGCCGCTGACCTTCATCCAGACAGACAAACCGCTCTA[C/A]AATCCAGGACAGAGGGGTGAGCTGTGAGAGCTTTATCAGAGTATTAGTGA
Long Flanking Sequence:
TGACGTTTCCTTCACTGATTGAGTCTGACACTGAAGCTAAACTGTGCGCTAGTCTTCTGAAGCCCAAAGGGAGTGTCACAATGACCATTTCTCTGGTCGATGAGAAAAGCACCGAAATTCAACTTGTGCAGCAGACGTCCGGGAGGAAGTTTCACAGATGTTTTCATTTCCAGGTTTGAGTTTTTCTTGTAATAGTTGTAGTTTTCCTCAGTTTAACATCCACCAAAAACCAGTTCTCCCCAAACATGTATAATATCTAATACCTAATATCGTTGCTTGTGTTGAACAGAACGTATTCAGGTTTAAGTTGAGGAAATGGGAATTTCTAGGTAAAATATCCACTTTATTGGTTCTCTGCAGGCTCCTCAAGTAAGTGGAGATTCAGTGCAGACTGTGAGGGTGGTCATTCAAGGACAGTCCTTCAAAATGACTGAAGAGAGTAAAGTTATGTTCAGGTCTTACCTGCCGCTGACCTTCATCCAGACAGACAAACCGCTCTA[C/A]AATCCAGGACAGAGGGGTGAGCTGTGAGAGCTTTATCAGAGTATTAGTGAAGAACCTCTAATAAGAGGTTCATTTAGCAAAACAAAATTATATCTATTTAGAACCCAAATGATGGTTATGTTGTGTGAATATGCCGCCTCATCAGTACAGTCTAGCAGGTGCTTTATCACCTTTTTTTTTTTTTCCCTCTCTTTCCCGCCTACAGTTAATTTCAGAGTTCTTACAATGAGTGATACATTTGTGCCCCAAGACCAAATGGTAAGATCTTTATTTTTCCAGTTCCCTAATACAGCTTTTCAAACATCATTGGCTAATGGTAACCTTTTTGTCTTTCAGTACAGTCTGGTGGTGGTGGAGGTAAGAACTGGTATTCATGGTTCGATGCAGAAATGTTTTTTTTTTTTATTTATTTATTTTTTTGTGCTGTTAATTTCATTAGGACAATAACAAGATCCGGATTCGTCAGTGGACCGACATTTCCTCCACAAACTGGATACTGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39972
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024900 Essential Splice Site 1178 1456 27 34
Genomic Location (Zv9):
Chromosome 3 (position 3997229)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 3681628
GRCz11 3 3463881
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTCGAGCACAGCTTTTAAATTCCTTGAGAAACACTGCCATTTCTGAAGG[T/C]AACTTATCCATAAAATTAAGTTAGACCTGTTTCTAATTGGATTTAGCGAT
Long Flanking Sequence:
CCTACATAGATCCCAATGTCCTTCAGAGCGCAAAGGACTGGTTGATTGGCACGCAGGGTTCAGATGGTTGTTTTGTGCAACAGGGGACTCTGTACCACAAAGACATGAAGGTATGTCACCTTTCTTCAAAGATTCTATAAACGAGGCTGATCTTGAAGATGCTGCTGTGTTTTAGGGTGGGGTTGATGATAACGTAACCATGACTGGCTACATCGTTGCATCAATGCTTGAAATTGGAGTTCCAGTCACGGTAAACTAACTAATTTTCCTTAAAGTACCCCAAACATTGACCTATCCATGTCATTAAACTGACTAAAGTTGACTCTCTCCTTCCAGGATCCTGTCATTACGAAGGCTCTGTCGTTTTTGAGGCCTCTTGTTGGGAATCTGGGAAACACCTATGTAACTGCTCTGCTGGCCTACACCTTCAGTCTGGCTGGAGAGACCAGCACTCGAGCACAGCTTTTAAATTCCTTGAGAAACACTGCCATTTCTGAAGG[T/C]AACTTATCCATAAAATTAAGTTAGACCTGTTTCTAATTGGATTTAGCGATGAGATTTCCTCTGTCATTGTGTCCAAGGTTTTCTTGCTTAGAAAAACACTCCTTGTGTTTAGGTACTACTCTCCACTGGTCTCAGACGACATCTGGGGATACTCTGGCAGTGGAGATCAGTGCATATGTGCTGCTAGCGGTTCTAACTGTACAGCCTGTGACCACTGCTAATCTGGGCTATGCTAACCGCATTGTCAACTGGCTCGTGGCCCAGCAGAATCCCTATGGTGGTTTCTCCTCCACTCAGGTGAGTTCAGCTAGGAAATGATATCGTAATTCAGGCATGGTTTAACATTTGAACTAAAGTGCGTTATTTGGGGCATTGTGTAACTTGTACTGAAACTTGTTTGATTACCTTGAAGCTCACGCTTTTACAAAAACTGCACTGCATTCAAGATACCTCTACCAAATAATATAAATATAGGATGTTTTCTAGTGAAATACAGATGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39973
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024900 Essential Splice Site 1381 1456 31 34
Genomic Location (Zv9):
Chromosome 3 (position 3998495)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 3682894
GRCz11 3 3465147
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTGGTGGACATCAAGCTCTTGTCAGGATTCACTGCAGACACCTCACTGG[T/C]TGGTGTGAGTTTTCAGGTTGACTTTTTGGGATGCTTGAAACTACTTGCTG
Long Flanking Sequence:
GTTCAACTTTGACGTGACTCCCAACAACCGCCTGCTGTACCAGGAGAGTCCACTGAATAACTTTCCAGGCACATACAGTGTTGTAGCAGCTGGAGCTGCCTGTGCTTCTGTACAGGTGTGTGTGCTCGCTCATTTATGTTGGTGGATTGCTCGCATGGATTCATTGTCTTATTTTTATGCCCACAGGTTTTATGTTTCTACAACATCCCGACTCCTGTTAGAGTTTCTAAAACACTGAGTGTTGTTGCGAAGGTGTCTGGAAACTGCCAGGCTACACCAGTCAATCTGATGTTGACCTTTACGGCCAAGTAGGAACCACTTCCTTTGTTTTTGTACCAGGGCCTTTAAGGTCGCATGTATATTTCAGAACTTTTTGACCTCAAAGATGATCGCCTTTTTTAAATCTCAATTTTTCAGATACACTGGTCCAAAACCAACTACTAACATGGTTCTGGTGGACATCAAGCTCTTGTCAGGATTCACTGCAGACACCTCACTGG[T/C]TGGTGTGAGTTTTCAGGTTGACTTTTTGGGATGCTTGAAACTACTTGCTGAGTGTTTTCTTTCTTACAGCTTGGATCTCCACCCAATTTCGCTCCGTTAGTGCAGAGGGTTGATTCTGAAGGTGATCATGTCCTTATCTATCTACAAGAGGTGAGACTGGAGTTTCTATTTAACCTGCTACCTCAACTGTCAGGACTTGAGTCTAGTATTCACCATCTCTGACACATTAGCTTGCATTAAAGCATTTCTAGGTTTTAAGTGTGTCTCTCTCTCTCTCTCTTTTCCAGGTTCCCAAAGGTGTTCCAGTGACCTTCAGTATACAGCTGACACAGACTGTTGCAGTGCAGAATCTCAAGCCAGCGGTCATCAATATCTATGACTATTACCAGAGAAGTATGTTTGTTATAATTGAGCTGAATTTACTGTAGCTGGCACTCATGCTCTGCTTCTTTTTTCAGGTGACAGTTTTGAGACCGCCTACAAGTCCCCCTGTCCATGAT
Associated Phenotype:
Not determined