ZMP
WFS1 (1 of 2)
Ensembl ID:
Description:
Wolfram syndrome 1 (wolframin) [Source:HGNC Symbol;Acc:12762]
Human Orthologue:
WFS1
Human Description:
Wolfram syndrome 1 (wolframin) [Source:HGNC Symbol;Acc:12762]
Mouse Orthologue:
Wfs1
Mouse Description:
Wolfram syndrome 1 homolog (human) Gene [Source:MGI Symbol;Acc:MGI:1328355]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa45069 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa10021 | Nonsense | Available for shipment | Available now |
| sa11465 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa45069
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000090025 | Nonsense | 407 | 1061 | 7 | 9 |
Genomic Location (Zv9):
Chromosome 1 (position 13207747)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 13636489 |
| GRCz11 | 1 | 14323002 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTCAAACAGGAAAAAAACGAAATGGCTCCTGTTACTCATAAGCGCCAA[C/T]GAAAGTCTAGCTGGGGAATGAGGAGCAGTGGGTTGATGCTGACTACCAGA
Long Flanking Sequence:
TGTAAAATTGAGAGAGGAGTAATGAAGGTATAGACCACAATATCAAAAAGCATGGCTTCGGTTCAGAAAAAGGCTTTTTGGGGCCTATTTGGACAAAATAATATCTAGTGGATCTTAGACAGGAGCAACTGTGTCTGTTTGACTTGTCATCTGAGCAATACTACAAACGGGTTGAAAAAGAAAAAAGTAAGGAGACAAAATGCTAAATGCTAATAGTTTGTTGTGGGACGTAGTGTGCAGACTGAGACAAAGTTGTTGGCAGTGTGAATACAACAGCATTGGAATACTACCCTAGATAGTCATGCAGGGTGAAAACATCTGTTATGCAACTACTCTGAAAATCGTGCAGTCTGAACTCGGTATCACTGTCCTTGGTTATAAATCAAATTAAAATCTTAAAAAAAGAGTGTAATGGTTTCAAATGAGCTGCAAGACTTAAACGTTCTGCTATTTTCAAACAGGAAAAAAACGAAATGGCTCCTGTTACTCATAAGCGCCAA[C/T]GAAAGTCTAGCTGGGGAATGAGGAGCAGTGGGTTGATGCTGACTACCAGACGCAGCGATGCCATGAGGAGAGCCCTGGACATAAAAGCTCACTTTTTGGTGAAAAACTAATAAACAAACTTGATGCAGAAGTGACTGATATTCACAATCATCATTAGTTTATTGAAGTTTTACTTCAAACACATCACACACAGATTTAAATGTTCATTCTTTCACTTTAGGGTCTGCAATATCCTCTTCATGCCATTATTGATATGAAGGAACATTTAATTGACTGGGCGTCTCGTGCTGGTGTCCAGTGGCTGAGCACTATTATCCCGACACAACATGTCAATGCCCTTATCTTCTTCTTCATCATCTCCAATCTCACCATCGATTTGTTTGCCTTCGCCATCCCGCTCCTCATCTTCTACCTGTCCTTTATTTCCATGGCCATCTGCACACTGAGAGTCTTCCAGAGCAGCAAAGGTTGGGAGAACTTCCGTGCCTTTACCGCTCTCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa10021
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000090025 | Nonsense | 692 | 1061 | 9 | 9 |
Genomic Location (Zv9):
Chromosome 1 (position 13199706)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 13628448 |
| GRCz11 | 1 | 14314961 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTTCAGAGGGACGTACTGTTTCCTGGTGCCGTACTTGGTCTGCTTTGTCT[G/A]GTGYGAGTTCTCTGTGGTTCTGCTTCGGAACTCCACCACCATCGGCCTRA
Long Flanking Sequence:
CTAGTTATATACATTAGATGAAAGCCTGAAGACCTTTAATTGGGTGTTAATTGTGATTTACTGTTTAAAAGTTTTGACTGCCTCAAACAAAGTTAATGGGATTTTTTGTAGTTTCAGACATTTTATAAATAAATCTTATGTTTGATTAAAGCTTAGTTGTAGATCAGCCTAAAGCAGGGGTGTCCAAACCTGTTCCTGAAGGGCCAGTGTCCTGCAAAGTTTAGTTCCAACCCCAATCAGACACACCTTGGCAACCTAATTAAGCTCTTACTAGGCTTTCTAGAAATATAACTGGAGGTGTGTTGGGGCAAGTTGGAGCTAAAATCTGCAGAACATCGCCCTCCAGGACCAAGTTTGGATTATATATTTTGAAACTGATGTATCAATATCAAATATCATGATCAAACCTACCTCTTTTTTTGCTGTTCATAGTATGGCGCGCATGAGGGGCTTCAGAGGGACGTACTGTTTCCTGGTGCCGTACTTGGTCTGCTTTGTCT[G/A]GTGCGAGTTCTCTGTGGTTCTGCTTCGGAACTCCACCACCATCGGCCTGATCCGTACTTGTGTTGCCTACTTCCTCTTCCTGTTCGCCCTACCAGTGTTAATCATGGGTCTGATAGCTTTGCTGCTGATTCAGCTGATTAAGTGGTTCCTGGAGTTAGAGTTAACTAAGATGCTGGTGACCCTGGCAGTGTGCGCCGTCCCTGTGACACTGCGACTCTGGACTCGATTTAGCCTCTCAATTCTGAATGTCTTCCGCTCCATCACCCACCGAGGTCCAGTCAAACTGATCCTCCTGTGCATCACTACAGTGATTTTACTCTGCGGCGTCTATGTTTATAATGCTGAAGGCCTCAAGGTTTATAACTCCACACTCACCTGGGAGGAATATGGCACACTGTGCGGCCCGCAAGCCTGGAAAGAACGAGGAATGGCTCAAACGCAGCTCTCCTGCAGCCATCTGGAAGGCCATCGTGTCACATGGACAGGAATATTCCGTTATG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa11465
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000090025 | Nonsense | 825 | 1061 | 9 | 9 |
Genomic Location (Zv9):
Chromosome 1 (position 13199306)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 13628048 |
| GRCz11 | 1 | 14314561 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTCAAGGTTTATAACTCCACACTCACCTGGGAGGAATATGGCACACTGTG[C/A]GGCCCGCAAGCCTGGAAAGAACGAGGAATGGCTCAAACGCAGCTCTCCTG
Long Flanking Sequence:
ATCAAACCTACCTCTTTTTTTGCTGTTCATAGTATGGCGCGCATGAGGGGCTTCAGAGGGACGTACTGTTTCCTGGTGCCGTACTTGGTCTGCTTTGTCTGGTGCGAGTTCTCTGTGGTTCTGCTTCGGAACTCCACCACCATCGGCCTGATCCGTACTTGTGTTGCCTACTTCCTCTTCCTGTTCGCCCTACCAGTGTTAATCATGGGTCTGATAGCTTTGCTGCTGATTCAGCTGATTAAGTGGTTCCTGGAGTTAGAGTTAACTAAGATGCTGGTGACCCTGGCAGTGTGCGCCGTCCCTGTGACACTGCGACTCTGGACTCGATTTAGCCTCTCAATTCTGAATGTCTTCCGCTCCATCACCCACCGAGGTCCAGTCAAACTGATCCTCCTGTGCATCACTACAGTGATTTTACTCTGCGGCGTCTATGTTTATAATGCTGAAGGCCTCAAGGTTTATAACTCCACACTCACCTGGGAGGAATATGGCACACTGTG[C/A]GGCCCGCAAGCCTGGAAAGAACGAGGAATGGCTCAAACGCAGCTCTCCTGCAGCCATCTGGAAGGCCATCGTGTCACATGGACAGGAATATTCCGTTATGTTCGTGTAGCAGAGAAGGAAAATGGAGCTCAGTCTGTTATAAACATGCTACCGGTGTTCATGGGCGACTGGTTGCGGTGTCTCTACGGTGAGGTTTATCCGAAGTGTGAACCACAAAACAATTCATTTCCGATCGTGAATGTTACTCAAGTCACCACAGGAACTGTCAACACAACAATACTGATCCTAAGGCAGGAAGAGGAAGAGTTATGTCGGATAAAAGCTTATGCTACACACCAATGCCACGTTAAACGTTTTGACAGTTACCGTTTCGAGGTGACGGTTGGCATGCCGGTGGATGGTGTCACAAAAGTGGACAATCCAGCAGGTGACATTCTCTTAATGGCAAGTCATGAATTCAGACAAGTGCTGCTGAATCTTAACCCAGGCAGCATGGTGGA
Associated Phenotype:
Not determined