ZMP

pitx3

Ensembl ID:

ENSDARG00000070069

ZFIN ID:

ZDB-GENE-041229-4

Description:

paired-like homeodomain transcription factor 3 [Source:RefSeq peptide;Acc:NP_991238]

Human Orthologue:

PITX3

Human Description:

paired-like homeodomain 3 [Source:HGNC Symbol;Acc:9006]

Mouse Orthologue:

Pitx3

Mouse Description:

paired-like homeodomain transcription factor 3 Gene [Source:MGI Symbol;Acc:MGI:1100498]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa45	Essential Splice Site	Confirmed mutation in F2 line	Not yet available
hu3263	Nonsense	Confirmed mutation in F2 line	Not yet available

Mutation Details

Allele Name:

sa45

Status:

Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000102538	Essential Splice Site	105	293	3	4

Genomic Location (Zv9):

Chromosome 13 (position 6668455)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	7232768
GRCz11	13	7564970

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GCGAGAGGAGATTGCGGTGTGGACCAACCTCACAGAAGCAAGAGTACGGG[T/C]ACGTGTGTCCCTGCCAAACTAAACCGCTGCATAGCTACGGCACATTGTGT

Long Flanking Sequence:

CAGGATTATGTGGCCAGCTAATTTAGCCCTTTCTGTGGGGTCTTGCATTTGCAATTTGCAGAACTCTGTAGACACCACAGAAGGAGGATTTTCATCACACATACACAAAAAATAAATAAAAATGAAAACCACTCTGGACCCTGCAGCTCTTGTTTTGTAGCTAAACGGAAACTAAGTAGTTTTGTGTAGTTAGCATAAACATGTTTATATGTAGCTAAGTTTGTTTGGAATCATGTTTGTGATAATATGACAACTATTTTGCTTAATTAATGCTTTTTTCCTGACCCATACAGACACAGAGAAGTCCCATCAGAACCACACAGATGAGTCGAACCCAGAGGACGGCTCTCTAAAGAAAAAACAGCGCCGGCAAAGGACACATTTCACTAGCCAGCAGCTCCAGGAACTGGAAGCCACCTTTCAGAGAAACCGTTATCCCGACATGAGCACGCGAGAGGAGATTGCGGTGTGGACCAACCTCACAGAAGCAAGAGTACGGG[T/C]ACGTGTGTCCCTGCCAAACTAAACCGCTGCATAGCTACGGCACATTGTGTTTCAGAAACAGTTGTAGATGTTTTAATCAAACAAATATATAATCGGCACGCTGACTGATGCAGATAAGGAGTTCACTATGTTGTCACTATGGTACATTTGTGTAATGAAAGGGCGTCCTTTTAAACACAAGACATAAATTATAGGCCTGGGCTATTCCAGGAGTTTCAGGAATACTTAAAGGGATAGTTTATCCAAAAATGACAGTTGCTTCTTCTGCTGAGCACAAATGAAGATGTTTTGAAGAATGGTGGTTGCTGCGGGACTCATCGACTTCATTAATAGGAAAAAAATACTATTGAAGTCAATGGGAAAATCATTTTAAAAAATAACTTCTTTTAAGTTGAGCTGAAGAAAGAAAGTCAAATAGGTTCTGAACAAGTTAAGGGTTAGTAAATGATGACAGAATATTCCTTTTGGGGTGAAGTAACCCTTAAACTGAAGACACTTTT

Associated Phenotype:

Normal

Stage	Entity	Quality	Tag
Larval:Day 5 ZFS:0000037	whole organism ZFA:0001094	quality PATO:0000001	normal PATO:0000461

Mutation Details

Allele Name:

hu3263

Status:

Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000102538	Nonsense	250	293	4	4

Genomic Location (Zv9):

Chromosome 13 (position 6676223)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	7225000
GRCz11	13	7557202

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGTCAGCAGCCGCCTGCCCGTATGCCACCACGGCCGGTCCATACATGTAC[A/T]GAGACACCTGTAACTCCAGTCTGGCCAGCCTCCGGCTCAAGGCCAAACAG

Long Flanking Sequence:

CTTTTCTGAGTGTACGTTGACAAACGATCTGTAATCTGACCACTGGTTTCTTGCTATCTTTTCGACAGGTGTGGTTTAAAAACCGCCGAGCCAAATGGAGAAAGCGAGAAAGGAACCAGCAAGCCGAGCTGTGCAAGAACGGCTTCGGCGCCCAGTTCAATGGACTCATGCAGCCGTATGACGACATGTACTCTGGCTACTCCTACAACAACTGGGCCACTAAGAGCCTGGCCAGCAGTCCGCTGTCAGCCAAAAGCTTTCCTTTCTTTAACTCCATGAATGTAAGCCCGCTGTCCTCCCAGCCAATGTTCTCCCCGCCCAGCTCCATCCCTTCCATGAACATGGCCTCATCGATGGTGCCCTCGGCGGTGGCAGGGGTGCCGGGCTCAGGCCTTAACAACCTGGGAAACCTGAACAACCTGAACAGCCCCACCCTCAATTCTGCAGCCGTGTCAGCAGCCGCCTGCCCGTATGCCACCACGGCCGGTCCATACATGTAC[A/T]GAGACACCTGTAACTCCAGTCTGGCCAGCCTCCGGCTCAAGGCCAAACAGCACGCCAACTTCGCCTACCCGGCAGTGCAGAACCCTGTTTCCAACTTAAGCCCCTGCCAGTACGCTGTGGACCGGCCGGTATGAAAGCGATGCGTCTAGATTTCGAAAAAAACAAACAAACCCCGACACGAACTTCAAGCCCTTGTCTAGCCAACCCTACATTCGACTCTGAGGCATCATCACCCTACAATGAACTGGATTTCTGGGAATAAAGCTTCACGAGGAATGGAGCGTCACAATGGACCAGGCCTCAAAGAACTCATGCGATAACATGTTAAGACGCTGTCGCCGAACCGACCAACTGTTTAAAAGCTTTTGTCCGCTGCATGATTAGAGACAAAAGAGGACGTAAACACTTCCGCTGCACTCAGACCTCCCGAAAGAATATCATAGGCAGAGATAAGAGGATGTACATAATGGACTCTGTATTGTATGTGATAAAATATCTCG

Associated Phenotype:

Normal

Stage	Entity	Quality	Tag
Larval:Day 5 ZFS:0000037	whole organism ZFA:0001094	quality PATO:0000001	normal PATO:0000461