ZMP
sesn1
Ensembl ID:
ZFIN ID:
Description:
sestrin-1 [Source:RefSeq peptide;Acc:NP_001002660]
Human Orthologue:
SESN1
Human Description:
sestrin 1 [Source:HGNC Symbol;Acc:21595]
Mouse Orthologue:
Sesn1
Mouse Description:
sestrin 1 Gene [Source:MGI Symbol;Acc:MGI:2155278]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa14435 | Essential Splice Site | Available for shipment | Available now |
| sa23741 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa14435
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000062993 | Essential Splice Site | 56 | 488 | 2 | 10 |
| ENSDART00000147448 | Essential Splice Site | 56 | 499 | 2 | 10 |
Genomic Location (Zv9):
Chromosome 20 (position 32264383)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 32322623 |
| GRCz11 | 20 | 32225502 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCCCCAGACCAGTGGGAAATGGACCAAGTAGATTTATACCAGAGAAAGAG[G/A]TGAGCGTTAACATCTGCCCCGCTTGCTCAAAGTTAACAKAAATCTGGCAA
Long Flanking Sequence:
ATACCAATGTAATTAATAACAATGTATTTTTTTGCACAATTTCTTGCATATCCCTATCTGATTCAGCAATTTTTCATGTTTATGTCACTGGTGCATTGCAAACTCAGCCAACCTTTGTTCATAAGGTATCTAGGCTGTTTTGAGTCATTCTCTTTGTGTCTTTGACAGTGAGAAGATGAATGATGTTCAAGATGAATGATCATTTGCTACTTATATTATAATGCATTTTTGGTTATGTATTATAAAGGATTTATTTACTACTAAATGCCGTAGAATATTCTAGAACCAGCCGTTGATGTTTGAGCTGAGGAAGGATGTTGTTTTTAAGAGCTCTGGTCTGATGCCAGAAATTCTTCGATACTAGTATAGCTTCATGCCAAGAGCTTCTCTGTGGTTTTCGATCATGTAATCATGTTTTTTTCAATCTTTTCTAGGATGTTGGAGTGCGAATCCCCAGACCAGTGGGAAATGGACCAAGTAGATTTATACCAGAGAAAGAG[G/A]TGAGCGTTAACATCTGCCCCGCTTGCTCAAAGTTAACATAAATCTGGCAACAATCATTTTTAATCAACAAATGGCACCTCTGTTATTTTTAATCGCACAAACAGCATTTATCATACACTTTAGTGAAGTTATTTTACCAGCACTGAATTCCTCAGGTTCACCGCGTCTCTACTCCCCTGTTGTCCCAGATACTTCAAGTCAGTAAATTGGATGAAAGGACACAGTCGATTTTTGAGGATGCCTTTGCAGTGCTTGGTCGCCTCGACAACATCTCCTTGGTCATGGGGTTTCATCCTCAATATCTGGAGAGCTTTCTTAGGACACAACATTACCTCCTTCAGATGGACGGTCCATTGTCTCTGCACTGCAGGCATTATATTGGAATAATGGTGAGGTTGCAGACGGTATTTTTTGTATGAAATTCAAAAACCCCAGTGGTAGCTTGTTCTAAATGCTTGTGTCTGTGTTCAACAGGCTGCTGCTAGGCACCAGTGCACGTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa23741
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000062993 | Nonsense | 68 | 488 | 3 | 10 |
| ENSDART00000147448 | Nonsense | 79 | 499 | 3 | 10 |
Genomic Location (Zv9):
Chromosome 20 (position 32264605)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 32322845 |
| GRCz11 | 20 | 32225724 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCCCCTGTTGTCCCAGATACTTCAAGTCAGTAAATTGGATGAAAGGACA[C/T]AGTCGATTTTTGAGGATGCCTTTGCAGTGCTTGGTCGCCTCGACAACATC
Long Flanking Sequence:
GCATTTTTGGTTATGTATTATAAAGGATTTATTTACTACTAAATGCCGTAGAATATTCTAGAACCAGCCGTTGATGTTTGAGCTGAGGAAGGATGTTGTTTTTAAGAGCTCTGGTCTGATGCCAGAAATTCTTCGATACTAGTATAGCTTCATGCCAAGAGCTTCTCTGTGGTTTTCGATCATGTAATCATGTTTTTTTCAATCTTTTCTAGGATGTTGGAGTGCGAATCCCCAGACCAGTGGGAAATGGACCAAGTAGATTTATACCAGAGAAAGAGGTGAGCGTTAACATCTGCCCCGCTTGCTCAAAGTTAACATAAATCTGGCAACAATCATTTTTAATCAACAAATGGCACCTCTGTTATTTTTAATCGCACAAACAGCATTTATCATACACTTTAGTGAAGTTATTTTACCAGCACTGAATTCCTCAGGTTCACCGCGTCTCTACTCCCCTGTTGTCCCAGATACTTCAAGTCAGTAAATTGGATGAAAGGACA[C/T]AGTCGATTTTTGAGGATGCCTTTGCAGTGCTTGGTCGCCTCGACAACATCTCCTTGGTCATGGGGTTTCATCCTCAATATCTGGAGAGCTTTCTTAGGACACAACATTACCTCCTTCAGATGGACGGTCCATTGTCTCTGCACTGCAGGCATTATATTGGAATAATGGTGAGGTTGCAGACGGTATTTTTTGTATGAAATTCAAAAACCCCAGTGGTAGCTTGTTCTAAATGCTTGTGTCTGTGTTCAACAGGCTGCTGCTAGGCACCAGTGCACGTATCTGGTCAACCTGCACGTGAATGACTTCCTGCAGGTCGGAGGTGATCCGAAGTGGTTGAATGGTCTGGAAGAAGCCCCACGGAAGCTGCAGGCTCTCGGGGAGCTCAATAAGATCCTGGCCCACCGCCCCTGGCTGCTCACCAAAGAACACATTGAGGTATGACTTCAGCCTCACGGTCACTCGTGGAAACTCGCCAACAGTTGTTATGCAACTGTAATGAG
Associated Phenotype:
Not determined