ZMP
irx6a
Ensembl ID:
ZFIN ID:
Description:
Iroquois homeobox protein 6aIrx6a protein [Source:UniProtKB/TrEMBL;Acc:Q503Z8]
Human Orthologue:
IRX6
Human Description:
iroquois homeobox 6 [Source:HGNC Symbol;Acc:14675]
Mouse Orthologue:
Irx6
Mouse Description:
Iroquois related homeobox 6 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1927642]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa21007 | Essential Splice Site | Available for shipment | Available now |
| sa44671 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa1145 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa21007
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000045628 | Essential Splice Site | 16 | 477 | 2 | 7 |
Genomic Location (Zv9):
Chromosome 7 (position 36969797)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 35243640 |
| GRCz11 | 7 | 35515117 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTTGAAACGCAAATAAAAAAGTCATGTTTATCCACAATTTTCTTCATGC[A/T]GTTTTTCGTGTCGGCAACCCCCAGTACGACTTGCTGCGATTCGATATCCA
Long Flanking Sequence:
TGTAATTGTTTAGTGAGAGCGAGACTCCTCCCTTTGCCGGTAGCCTTTGCCGTCTCTGTGTATAAACTAATTACAGATTTACTGATAACATAGATAATTTCGACAACATGACTTAAGTCAAACTCAAGTTTTATTTAAAGTCGACAGATTGTTTAATTGTCAAAATAAGCCGCGCTCACTTAACTTCTCCTGTCCTGAGGCAAAACTTAGAAAGTTTACTTTCAGCTTTGACAAAATCACTTTTTGAAAAATTAAGTAAGACAAACCCTTTGCCTTTTTATTTTTAAGTCATTTACACAAAGTCTCAATTCAGTTAAACTATAGGATTATCTTTATGAATAAAACGAATGAATGAAAATAATTGCAATCGGTCTCCAAAGAAAAAGAGCTGCTTTACCACAGAGCAGCTCCATCTTACCTTAATTCTTTTTCAAACTACGGAAACGCCTGCTTTGAAACGCAAATAAAAAAGTCATGTTTATCCACAATTTTCTTCATGC[A/T]GTTTTTCGTGTCGGCAACCCCCAGTACGACTTGCTGCGATTCGATATCCAGGTCGGTGACAGAAGGATCGAGCGCATCGCAGACCGCAGCCTCCTTCTGCTGTCCCTCCTATGAGAACCGGCTGCTGGCGAGTACACGGACGGAGCTCAACGCCGCGCTCGGGATGTACGGCTCCCCTTACGCAGCAGCAGCGGCCGCAGCCGGGCAGAACTACGCCAACTACTTTCCGTATAGCGCCGACCCCTCCGCCATCTACTCCAGCCTGGTACGTGCAGCACTTCACCAGATAAAGCGGGTCCTCCGTTCAATCGATTGTCTCATTCATGTCACGGCTTGTTATTGATTATTTTGGCTTGGTAAGAGGATCAAGCTGTCTAGCACTCTGGTGAAATAACTGAATAATCAGAAGAAATGAACAGAATGAAGCAACATTGCATGACGCCTGCTTGCTATAAACAGGGCCTACTTGGTTTAATGGACAATAAATAGACAGAAATGTG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa44671
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000045628 | Nonsense | 214 | 477 | 4 | 7 |
Genomic Location (Zv9):
Chromosome 7 (position 36968688)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 35242531 |
| GRCz11 | 7 | 35514008 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGGTTTGCCAATGCTAGAAGACGACTAAAAAAAGAAAACAAGATGACTT[G/A]GTCCCCCAAAAACAAAGCAGGCGATGACAGGAAGGAAGACCTCGGTAAGA
Long Flanking Sequence:
ATAACTGAAATATCAGATGCTAAAGTCTATGTTTTTTTTGTTGTTTGTTTGTTTTTTATTGTTTATATTTAGAACCCACAATATGAAATCAAAGAGGGGTCAGGCAGTCTTCATAGCACTATAACACAACCAGCCACTTACTATCCATATGACCACTCACTCGGACAGTACCAGTATGACAGGTGAGATTTGTTTTTATCCCATTTCTAATATGGCATATTTTAATATACTTAAAATGCAGATAAATGATCCAGATATTCCACTATTTATTTGATCCAGGTATGGGACAGTTGATTTTAATGGATCAACACGGAGAAAGAACGCCACACGTGAGACAACAAGTACGCTTAAAACATGGCTTTATGAGCACCGCAAAAACCCTTATCCTACAAAGGGTGAAAAGATCATGCTGGCCATTATCACCAAAATGACCCTCACGCAAGTGTCTACCTGGTTTGCCAATGCTAGAAGACGACTAAAAAAAGAAAACAAGATGACTT[G/A]GTCCCCCAAAAACAAAGCAGGCGATGACAGGAAGGAAGACCTCGGTAAGAGTGACCCAGACATTACCAAAGGTACCTCATAAATTTTCTCCGCTGCAGTTAAACAGTGTTTTTGTTTTATAAATGAATTTGGACGCTCACTTAGTACTTCTAATTCCACTTTCTCAGACTCCAAAGACAGTAAGGATGAGCAGGACCTGCAGTTCAGTGACCTGGATGATATGGAGGATGAGGACTGTGACAAGCTGGACAGTGACTGTGAAAAATCAGGTCAGGATGACCTCCCGACCTCCTCCCCTCCAAAGAGAGACTGTAACCCTGACATCCCTCTCCACTCCAACTTCCCATCTTTTCCCTGTGGTCTGAAGAGTTTGGGGCCTCTGAACCCAGACTACCTAGATCATCTGGGCTCCAAACCACAGCAGCAACAGCCCTCACCTCAGTCCACCTCCATAAACACTGTGGCACTCTCTCACTTTGAGTCATCGGAGAAGCCCCGGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa1145
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000045628 | Nonsense | 225 | 477 | 4 | 7 |
Genomic Location (Zv9):
Chromosome 7 (position 36968656)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 35242499 |
| GRCz11 | 7 | 35513976 |
KASP Assay ID:
554-1056.1 (used for ordering genotyping assays)
KASP Sequence:
AAGAAAACAAGATGACTTGGTCCCCCAAAAACAAAGCAGGCGATGACAGG[A/T]AGGAAGACCTCGGTAAGAGTGACCCAGACATTACCAAAGGTACCTCATAA
Long Flanking Sequence:
TTTTTTTGTTGTTTGTTTGTTTTTTATTGTTTATATTTAGAACCCACAATATGAAATCAAAGAGGGGTCAGGCAGTCTTCATAGCACTATAACACAACCAGCCACTTACTATCCATATGACCACTCACTCGGACAGTACCAGTATGACAGGTGAGATTTGTTTTTATCCCATTTCTAATATGGCATATTTTAATATACTTAAAATGCAGATAAATGATCCAGATATTCCACTATTTATTTGATCCAGGTATGGGACAGTTGATTTTAATGGATCAACACGGAGAAAGAACGCCACACGTGAGACAACAAGTACGCTTAAAACATGGCTTTATGAGCACCGCAAAAACCCTTATCCTACAAAGGGTGAAAAGATCATGCTGGCCATTATCACCAAAATGACCCTCACGCAAGTGTCTACCTGGTTTGCCAATGCTAGAAGACGACTAAAAAAAGAAAACAAGATGACTTGGTCCCCCAAAAACAAAGCAGGCGATGACAGG[A/T]AGGAAGACCTCGGTAAGAGTGACCCAGACATTACCAAAGGTACCTCATAAATTTTCTCCGCTGCAGTTAAACAGTGTTTTTGTTTTATAAATGAATTTGGACGCTCACTTAGTACTTCTAATTCCACTTTCTCAGACTCCAAAGACAGTAAGGATGAGCAGGACCTGCAGTTCAGTGACCTGGATGATATGGAGGATGAGGACTGTGACAAGCTGGACAGTGACTGTGAAAAATCAGGTCAGGATGACCTCCCGACCTCCTCCCCTCCAAAGAGAGACTGTAACCCTGACATCCCTCTCCACTCCAACTTCCCATCTTTTCCCTGTGGTCTGAAGAGTTTGGGGCCTCTGAACCCAGACTACCTAGATCATCTGGGCTCCAAACCACAGCAGCAACAGCCCTCACCTCAGTCCACCTCCATAAACACTGTGGCACTCTCTCACTTTGAGTCATCGGAGAAGCCCCGGATCTGGTCGTTGGCACGTACGGCCGCAGCAGGG
Associated Phenotype:
Normal
| Stage | Entity | Quality | Tag |
|---|---|---|---|
| Larval:Day 5 ZFS:0000037 |
whole organism ZFA:0001094 |
quality PATO:0000001 |
normal PATO:0000461 |