Busch Lab

ZMP

si:ch73-132m10.4

Ensembl ID:
ENSDARG00000054898
ZFIN IDs:
ZDB-GENE-070424-27, ZDB-GENE-081104-29
Description:
membrane-spanning 4-domains, subfamily A, member 17A.17 [Source:RefSeq peptide;Acc:NP_001082925]
Human Orthologues:
MS4A12, MS4A15, MS4A2, MS4A3, MS4A4A, MS4A8B, RP11-312N17.2
Human Descriptions:
Membrane-spanning 4-domains subfamily A member 18 [Source:UniProtKB/Swiss-Prot;Acc:Q3C1V0]
membrane-spanning 4-domains, subfamily A, member 12 [Source:HGNC Symbol;Acc:13370]
membrane-spanning 4-domains, subfamily A, member 15 [Source:HGNC Symbol;Acc:28573]
membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor fo
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) [Source:HGNC Symbol
membrane-spanning 4-domains, subfamily A, member 4 [Source:HGNC Symbol;Acc:13371]
membrane-spanning 4-domains, subfamily A, member 8B [Source:HGNC Symbol;Acc:13380]
Mouse Orthologues:
AC134839.1, Ms4a15, Ms4a2, Ms4a3, Ms4a4b, Ms4a4c, Ms4a4d, Ms4a8a
Mouse Descriptions:
membrane-spanning 4-domains, subfamily A, member 15 Gene [Source:MGI Symbol;Acc:MGI:3617853]
membrane-spanning 4-domains, subfamily A, member 2 Gene [Source:MGI Symbol;Acc:MGI:95495]
membrane-spanning 4-domains, subfamily A, member 3 Gene [Source:MGI Symbol;Acc:MGI:2158468]
membrane-spanning 4-domains, subfamily A, member 4B Gene [Source:MGI Symbol;Acc:MGI:1913083]
membrane-spanning 4-domains, subfamily A, member 4C Gene [Source:MGI Symbol;Acc:MGI:1927656]
membrane-spanning 4-domains, subfamily A, member 4D Gene [Source:MGI Symbol;Acc:MGI:1913857]
membrane-spanning 4-domains, subfamily A, member 8A Gene [Source:MGI Symbol;Acc:MGI:1927657]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa40337 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa44595 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa6954 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa40337
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099912 Essential Splice Site 98 293 3 8
ENSDART00000145536 Essential Splice Site 98 169 3 5
Genomic Location (Zv9):
Chromosome 4 (position 60394563)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 74914132
GRCz11 4 76495195
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCCTCCATCTTCGTCTTCAGTGGCGCTCCTTACTGGGGATCTGTCCTCG[T/C]AAGAAACAATCCCACAGCAGCGTTTTGCCATGGATAACACAAGCTACAGT
Long Flanking Sequence:
TTACCTTGTCAAGGAATTAAGGCCTTTGTGAAAGGCCAACCAAAAGCCCTCGGGGTGAGAAATCTCTCTGGTATATAAAACAATTGATTTTGATGTCAGTATGAATTTTAGCACACAACATACACCATTTTAATGACCTTAATAGGTTATTATAAGTTTATTGGCTTGGTGCCTTCGCAATTGTACAGTCATCTGATAATGTTTATAATCCAGAAGATAAATTTAGATAATTACTTATTAGAATGTTTTAGGAGCAAACCACTAAAACGGCTGAAGTGCTGAGCAAATATTTACTGTCCACAAATCCATGTGTACAGTCATAGAACAGGAATTTACTGTAAAAAGAACATCTCGTCCATCTTACACTGTTCTCTCTTATTCCTCACAGACTGTCCAGATAATGATCGGTCTGTTTACTCTCCTGTTGGGAATCGCATCTACAATTGATGCAGCCTCCATCTTCGTCTTCAGTGGCGCTCCTTACTGGGGATCTGTCCTCG[T/C]AAGAAACAATCCCACAGCAGCGTTTTGCCATGGATAACACAAGCTACAGTGAATAATCAACCAGAATGCAAATTACTGTCACATTTACAGCCACTAAAGAGATATAACAACAAATAAAACACAGTCGCATGACACTCATTCGCAAAATCTAGACCGGGTGGCACGAAATGGAAAGTTAGTCAGCACTGCTTGATAATAACTCATTTAGAATTGAAAACAAAATAACGAATAACAATATTGTATTATAATACTCATTCATGATTGATTAGTCAAGAAATACATAATGTTTTGGCTAATAGACTATAGATTATTAGTGACTAATATTTGAGTTTAGTTTGGTTTAAACTTCCAGTAGTTTATGATATATGTTGTAATGGCATTAGGGGATCTACTTAAGAGACCAATCACTTCTGAGTAGTAAGAAAACAGACCTATGAATAAGACTCCATACATATGGGTTGTAATTCTGCCAGGAGAGACTACATCCTACCTAGGCACAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44595
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099912 Essential Splice Site 121 293 4 8
ENSDART00000145536 Essential Splice Site 121 169 4 5
Genomic Location (Zv9):
Chromosome 4 (position 60391086)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 74917609
GRCz11 4 76498672
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCGCCATTGATGCTGAAAACAAACGTAATTCACCAACCAATTTATGTTTG[G/A]TATGTACACAACACTTGTTCTTTTCATGGGTCTAAGCACTGGGCGCTTGC
Long Flanking Sequence:
TTAGAGTTTCACATGTTTAGTTTTACCATCTGAGTGGATCATGAAGCTTATTGGCCATTCATATTTGATCCACCTTCCCTACCTGTGTTTTCTAAGACCGTGCATTTATTAGAAAATGTAGACGCTTAAAGCTCAAATATGAAGCAGTCTATATCCAATTATTTTTAAGGACAAAAATGTCCCTGGACAGTGGGGACACATCAGATACCTCATTAGTAAATGGCCGTGTTGTGCAAAAATACGAACAATACACATAGATGAAATTCTGTGACTGTGTGACTAACTGACGTGAGACTGGATTGTAAGGATGCAAATTGCATTTAGTAGTTGAGAGAATGGTTCATGTGGCAGTAAAATGCTCATTCTGGTTGAATACCACTGGTATGTATTCCAATATAAGCTTTGATTTTTGCTCTTCTCTCTGTTCTCAGTACATTACTGCAGGCTCACTCGCCATTGATGCTGAAAACAAACGTAATTCACCAACCAATTTATGTTTG[G/A]TATGTACACAACACTTGTTCTTTTCATGGGTCTAAGCACTGGGCGCTTGCAATTGACTTGGTCTGTAAGGATATGTGCATACATTGGTGTATCGGAAACAGATATTGCTATTTGTAAGATCTAAAACTTAAAACTCCTTATATATTTAATAATAATAAAACTTATTTCAAACTCCGACTAGACTGTTGTTTAACTGAAATATAAATCCTAGAAGTTGTTCATTAATGAAAGAATTATGATGACATTGGTGAACTAAACATTCTAAAAACACACATCTTTCACAAATGTGACCTTGTGAAGGCAACACAATTCATTTTCAGCTTGACATCATTTACAGCATCATTTACAACTTGACATTTGCCAATAAAAAAATAGAATAACATATCTGTATACTAAGTCTAATGCTGTGTTCCCACCAGATGCGACAAGCGCTGATAAATCACGATATTTGCGCAATATTCAGCTTCAATCGTGGGTCAAATTCACCTCACAACAGACAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6954
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099912 Nonsense 161 293 5 8
ENSDART00000145536 Nonsense 161 169 5 5
Genomic Location (Zv9):
Chromosome 4 (position 60388957)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 74919738
GRCz11 4 76500801
KASP Assay ID:
554-4686.1 (used for ordering genotyping assays)
KASP Sequence:
ATGGATATGCTTACTGGACAATTCWACRRTTACTGCAGTGACTATYATTG[T/A]GCAGAAATGGAGTTGAAGTATACGGTATGTTATTTACACAATTACAGTAA
Long Flanking Sequence:
AAGATTAATCAAAGCTACCTTAAAGGGTTAATTCGCCAAAAAATGAGAATTCTGTAGTTTATTACTCACTCTAATGTCATTCCAATCTCTCGAGACGGTCATTCATAATAGCAGAATTTAGTTTTTTCATCCTAACCAGTGGATGAGATCAAGTAAACAAAGTTTTTGTCCACATTTGCAAGCGAATGCAAAGGCTATGCAAGTAAATACAACATTTATCCTGATAATGTTTTCAGTTTTAGCATGAGCCTTTAGTGCTTGGACCTTATATTTAATTTATTTGTCAATTTTTTTTTTTAATCACTTTCCATATATTCTTCCAGCACAGTGAATTAGCGTGACATGTTGCCTAACTTTTCTGTTTTTGTGCCCTTACTGTAGGTGAAAGGGTCCCTTGGAATGAACATTTTCAGTGCTATAGTTGCAGGCACCGCCATTGTTATCATTTCAATGGATATGCTTACTGGACAATTCTACGGTTACTGCAGTGACTATTATTG[T/A]GCAGAAATGGAGTTGAAGTATACGGTATGTTATTTACACAATTACAGTAAGATCATTGTGTGATCCGGTACACTTATAAAGAACTGTCTAATGGTTTTCAGCGTTAATAAGTGCTGATCATTTACACTGGGTGAAAATATTGACGTTAAAAGTGCCATTGCAGTGTTGCCAGATTGGAAATGTCAAAGTATCGCATCAGAACCTCAAAATGATCGTATTTGGAGGTAAATTATTGTACACGAGTCAAACGGAGAGTATACAGCTATTACCTAGACCAGGGGTGGCCAACCCTGTTCCTGGAGATCTACCTTCCTGCAGATTTCAGTTGCAACCCATATCAAACACACCTGCCTGTAATTATCAAGTGCTGTTCAGGTCCTAATTAATTGATTCAGGTGTGTTTGATCAGGGTTTAAGCTGAACTCTTTGGCTGCGACCGAAACCGCCTATTACTCAGTAGGTACTGCATTTGAATTTAAACGTACTACTCGGCCGTTAGA
Associated Phenotype:
Not determined