ZMP

nmnat2

Ensembl ID:

ENSDARG00000004580

ZFIN ID:

ZDB-GENE-030131-8201

Description:

Nicotinamide mononucleotide adenylyltransferase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q6PC93]

Human Orthologue:

NMNAT2

Human Description:

nicotinamide nucleotide adenylyltransferase 2 [Source:HGNC Symbol;Acc:16789]

Mouse Orthologue:

Nmnat2

Mouse Description:

nicotinamide nucleotide adenylyltransferase 2 Gene [Source:MGI Symbol;Acc:MGI:2444155]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa39877	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa44539	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa39877

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000003550	Essential Splice Site	29	304	1	11

Genomic Location (Zv9):

Chromosome 2 (position 35761441)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	2	36058151
GRCz11	2	36040608

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TCATGTGGAAGTTTCAACCCCATCACGAAGGGACACATTCATATGTTCGG[T/C]AAGTGCTCCGCCTGGGCTGGAGGGAGTGGATGCGCGAGCGGATTTTTAAT

Long Flanking Sequence:

GCTCTGTTGAAGGTGTTGGCCCCAACATTCACAGATGGGATGGTCGCCAAATCAAAGGTTACCATGGGCCAACTTTAGCATCTATATATATATATATATATATATATATATATATATATATATAGCCTATATCTGTTCTGTTCTAAATCTAAACGGTCTCATGAATTCATGTTTTCCAAATCCCCCTTAAGTACTAAAAGAATCAGACTCGTTACGAAAATAAGAAGACTCGTTCAGATGAAACAGAATCGCAGCTCCTTGATTCTCGGCTCTCCGCGCATGTTCGTCAGAGCAGAGTGACGCTCGCGCTGCCGCAGCCTCATGAACCTCGCCTCTCGCTGCGGTCTCACAACAAAACAAAAGGCCCGAAAACCTACGACTTATGTTAAAAAACGATAGTTCGCCGAAGCCACAATGACGGAGAACACCAAAACGCATGTCATCTTGCTGTCATGTGGAAGTTTCAACCCCATCACGAAGGGACACATTCATATGTTCGG[T/C]AAGTGCTCCGCCTGGGCTGGAGGGAGTGGATGCGCGAGCGGATTTTTAATTCAGCCTTTTGTCTTATGTGTCGCTATGTGAAGGGAGTCCGAGTGACCCTGATGATTTTTAGCTGTTGTGATCGATTAGATGTTTTATTTCTGTGATGAACTTGTATTGTCGGTCGCTGTCCAGGGGGAAGGTGCTGAAATGGGCGACGGCCCATAATGATGGTGCTGCGCAGCCGCGGCTTTAGCTACATATATGTCTAGATTCATTCACAAATTTTAAGGACACAAGCAATAAAGAGTTGTGATTTATGGCATTTCAACAAGTGTAATTAATCTTTACTTGTGCGAAGGTTAACTTACTTGACACTATTGGAAGACAAATAACCTGCTGTGTAATTTTTAAAATATGAATATGTAATAATATGAATACGTAGGATGTTGACCTGTTAAAGCGATTCAGCCATTATCTATCATTTATTAACCTCTTGTTATAAAAACGCAAGAAAGTAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa44539

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000003550	Nonsense	271	304	10	11

Genomic Location (Zv9):

Chromosome 2 (position 35749527)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	2	36046237
GRCz11	2	36028694

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TAAAAGATGAAATCGACCACACGATGTCAATCGTCAGTTCCACCAAGAGC[A/T]GGTTTGTGTTCACCTCTCTATTCTTTACCATAATGTATGGTATGTACTTA

Long Flanking Sequence:

ATACCCATTTATTAGGTTGCCCAGCAACATTGCTTAAAAAGTTGCCCTGTGTATCATAAGCATTTAAAGTTTCTCATGCGATACTTCCGAACGTGCAATAACACTGGGTGATGGAAACTCAGATATAGTGTTGCTTTTAAAAGTCAGCATGAAATGAAAATTAATATTGTCATTTTTTCCCAAATTGTGATGTACTGTACATCCAATTGTCTAGATGGAGGTGATTGTTGGAGATTTCGGGATAGTTGTGGTGCCTCGAGATGGAGCAGACACAGAACGGATAATGAACCATTCCTCTGTGCTCAGAAAGCATAAGGTATTTGCATCAAATATGTTATAAATCACAGAAGACTATGTGTGGCTGTTTTACTACCGTCAGCACATTGGGATCAGGGCAAATTTATTGTATTAATGGCTTTGGTTTCCATTCACAGGATAATATAATTGTGGTAAAAGATGAAATCGACCACACGATGTCAATCGTCAGTTCCACCAAGAGC[A/T]GGTTTGTGTTCACCTCTCTATTCTTTACCATAATGTATGGTATGTACTTAAACTAAAACCACTTATGATATTGCCTTACTCTAACCCTACTCTTAATCTTCACAGAAAACCTGTAGTAAATTTTAAATGTAAAATGGACCACATTTAAAGTTTGGAGAAAAATCTAAATCTACAAAATCCGTTGTGGCGACCCCTAATGAATAAAGGGACTAAGCTGAAATAAAAATGATTGAATGAATGTTTGAGTTTCTTTAAATTCTATTGGAAAACAGCAGCCATTGCCTTCCATTATATTTTTGTTCCAACTATGAATGTCAATGGCTGCTGGTTTTCAGCACATTTCATAACTTCTTTGAGTAAATGATGACCCTCCTTAGTATAGTTTGGACTATCCTTGTATTTTTACTGTTGTAGGACATAACAATCAGGTTCTGGAAGCAAAAAAATAATAATAAAAAAAACCCACAAAATAATTATAAAGAAATTTATAAACATTTAGA

Associated Phenotype:

Not determined