Busch Lab

ZMP

ptch2

Ensembl ID:
ENSDARG00000055026
ZFIN ID:
ZDB-GENE-980526-44
Description:
Protein patched homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:Q98864]
Human Orthologue:
PTCH2
Human Description:
patched 2 [Source:HGNC Symbol;Acc:9586]
Mouse Orthologue:
Ptch2
Mouse Description:
patched homolog 2 Gene [Source:MGI Symbol;Acc:MGI:1095405]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa19807 Nonsense Available for shipment Available now
sa38340 Nonsense Mutation detected in F1 DNA Not yet available
sa44536 Nonsense Mutation detected in F1 DNA Not yet available
sa39869 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa19807
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077304 Nonsense 171 1442 3 22
ENSDART00000140910 Nonsense 171 1383 3 21
Genomic Location (Zv9):
Chromosome 2 (position 33701581)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 34000488
GRCz11 2 33983706
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTACCCAGGAGGCTTTGCTGCTCCACCTGGAGGCAGCTCTGTCAGCTAGC[A/T]AAGTTCAAGTGTCTCTTTATGGAAAGTGAGTACAACCACCAGCAACAGGG
Long Flanking Sequence:
GTGTGGACCATGTCACAATGTGTGCTAAAGACACAAATGTCATCCACACATCTGTTTCTGGGATTAGTTGTGAAGTGTACACAGGGGAATGAAAGCTTTAGTGAGTTTAATTGAAGGTTAAGTTGGGGCATAATTATGACATTAACATTTTCCTGAGGATCATGGTTGTTTCTTTATTGACTGATTGTTGCAGTCTGACCATTAACATTGTACTGTACTGTACTAACATAGCGCAGTTTCTTCTGGCTGACAGTCAACAGGAATATAATTTTCATGACCACAAAGGTGTATTCTTTCGTCAATGTTGAAAAATGCCTTGTTTTCTCTCTGTCTCAGCTGGCAGTCGAGTGAGCAAGGAGCTACGCTACACAAAAGAGAAGCAAGGAGAGGAGTCAGTGTTCACCTCACAGATGCTGATACAGACACCCAAACAGGAAGGAACTAATATTCTTACCCAGGAGGCTTTGCTGCTCCACCTGGAGGCAGCTCTGTCAGCTAGC[A/T]AAGTTCAAGTGTCTCTTTATGGAAAGTGAGTACAACCACCAGCAACAGGGAATTTCAAAAGCTTACAAATGCAAAAACATTTTATCATTTGCTTGTACAATTTCTACCCACAGATCTTGGGATCTTAATAAAATCTGCTTCAAATCTGGAGTTCCAATTATAGAAAATGTCATGATTGAAAGGGTAAGAATTATTTACTGTTTGCTTAGTCCAAGCTGTTGTAGTTTTTATAACTTTTTTTTTTGTTCTGTACCATAAAACTTTCTTTAAAGATGATACACAATTTCTTCACAGATGATTGATAAGCTTTTCCCCTGCATGATTGTGACTCCTTTGGACTGCTTTTGGGAAGGCTCCAAGTTGCAGGGAGGCTCCGCCTACTTACCGTAAGCATTCTGATTATTCTTAATTAATATATTGCCACATTTTTCCAATGAAGTTACCAGTCTAAGCTTTAGGGACAAAAAATTAACTACAGCACAAGGTTCTGTGTTTTAACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38340
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077304 Nonsense 515 1442 11 22
ENSDART00000140910 Nonsense 515 1383 11 21
Genomic Location (Zv9):
Chromosome 2 (position 33696627)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 33995534
GRCz11 2 33978752
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTTCTTGTTGGCTCATTCCTTCACAGAGACCCGATCCAACATCCCATTC[A/T]AGGCATGTATCTCATGAGCATGCTCTGGATCATGACTTTTAAACTCTGAA
Long Flanking Sequence:
TCTTAATGACATCATGAAATCTTTCTCTGACGTCAGCGTAATCAGGGTGGCAGGTGGTTATCTGCTCATGGTAAGACATCAATTACTGTAGCTGCTCTAGTTAAGGCTGATGAAAATGTGATCAGCATATATGTGTGGAGCTATTCTCTTACATATACCCTTTTTATGCACAGCTGGCATACGCATGCGTGACCATGCTGCGCTGGGACTGCGCGAAGTCTCAGGGTGCTGTAGGGCTGGCAGGAGTACTGCTAGTTGCTCTATCTGTGGCTGCAGGACTTGGACTGTGTTCGCTGTTGGGACTGTCCTTTAATGCCGCCACCACGCAGGTAAAAACACACCTAAACCTCTTAAATTCACACCCACCCTCAGGGCTTGGCTGTAACTCAGAAATTTGTGTTTCTCCACAGGTGCTACCATTTCTAGCCTTGGGGATTGGAGTTGACGACATGTTCTTGTTGGCTCATTCCTTCACAGAGACCCGATCCAACATCCCATTC[A/T]AGGCATGTATCTCATGAGCATGCTCTGGATCATGACTTTTAAACTCTGAAAATGTTGTTTAGATTTTCTGTTGTTGTTGCTGAAGATCACAGCTCATTTTTTTCTATTTATCTCCATAGGAGAGGACAGGTGACTGCCTGAGAAGAACTGGCACCAGTGTGGCTCTTACCTCAATTAATAACATGATTGCTTTCTTCATGGCAGCCCTAGTGCCAATTCCTGCTCTTCGGGCCTTCTCACTTCAGGTATGAGAGAGTATTTTGTTTGTGATGCATGTCATTAACCATTGTGCCATGAGATGTCTATTCAGAATGACTTGCAGGAGTGGTTACTCTCTGAAAAGGGCAGTGAAAGGTGGCTCAAATAAATGAGCAGTCAACCTTAATTTAAAGTAAGGCTGGCCTTTGTTGTTTCACTTTTTCGCATTCTCTCTCCATTTTATGGTCAATCCCCTTCATTCAACTAAAATCACTGCCTGGATTTCAGGTGGTTAGGGGATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44536
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077304 Nonsense 1040 1442 17 22
ENSDART00000140910 Nonsense 1040 1383 17 21
Genomic Location (Zv9):
Chromosome 2 (position 33693145)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 33992052
GRCz11 2 33975270
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGCTTGCCTGCACCTTCCTGGTGTGTGCCATCCTCCTGCTCAACCCCTG[G/A]ACCGCAGGCGTCATTGTAAGTCTGCCTTCCTCTCACTCTAATCCATTTCT
Long Flanking Sequence:
GTTTTTTATATCTACCTGACAGTATGGGTCAGTAATGATCCACTGGGCTATGCTGCCTCCCAAGCCAACTTTTACCCCCATCCTCGGGAGTGGATCCATGATAAGTACGACACCACTGGAGAGAACCTTCGCAGTAAGTAGACCTTGACAATGAGATTGGAAAGGTGGTCGAATGAATTCATGCATGTTTCACAAGTCATACAATCTTAAGAGCGTTACCTCTTGTCTCTTTCAGTCCCTGCGGCAGAGCCTCTAGAGTTTGCACAGTTTCCTTTCTACCTAAATGGACTAAGACAAGCCTCAGACTTTATTGAAGCCATCGAGAGCGTGCGCACAATCTGTGAGGAGTTCATGCGTCAGGGAATCAAGAACTATCCCAATGGCTACCCCTTTTTGTTTTGGGAACAGTACATTGGTCTGCGCCACTGGTTCTTACTGTCCATCAGTGTAGTGCTTGCCTGCACCTTCCTGGTGTGTGCCATCCTCCTGCTCAACCCCTG[G/A]ACCGCAGGCGTCATTGTAAGTCTGCCTTCCTCTCACTCTAATCCATTTCTACCTCCTTTCATTCTATCCCCCTATTCTCTTATTTCTCTTGCTCCCCTGATCCCCTCAACACAGCTCAATAACTTTGCCACCAGGGCAGTTTTTGGGGAGGGCCTTGTGGGTTGTCTAGAGGGTGCTGCTTGCATACACACATATATACACACAGTCACGCACATACGTACTCTCCCCCTCATTTCTTTTGTCATTCAAATGGGTGCAGCAAGACTTTCTAAAGAAGAAATTCAAAGCTCTCCTGAAGGCTTTTACCTCCAACTGCCTTTGTCCAGAAATTTGGGGACAGGACGGATCTGCCCAGTCACGACCTTGGCCTGCTAAACCCATCCATCAGGGATTTGGTGTAGTGGGGGTAGAGGGTGGTTGAGTTATTTCAGGGGCTAGAAGGCATTTCGCACAGACCGGTGTGCTCCTTAGTGCAACATGATGAAGCAACGGAACTAGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39869
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077304 Essential Splice Site 1431 1442 21 22
ENSDART00000140910 None None 1383 None 21
Genomic Location (Zv9):
Chromosome 2 (position 33687398)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 33986305
GRCz11 2 33969523
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGATCTGAATTCCACAGAAAAAGACCCACATCAAGCTAACCAGATGCTAG[G/T]TAAATAGCATTATATTTAAATCATCAAAACTAGACATTTGTATTTTTGCT
Long Flanking Sequence:
CTTGCTTTTTAAGGTGGTGAAACCATTTCATGAAGTACAGAACTGCGAGACTAAGCAGAATGCTGTCAACTCCATCAGCTCACAGATCAAACGGTGGGACAATAAAAATGAGGACCAGGGGCAGAGGAGACAACATTTACCTACTGACAGGACAAACTGTCAGCGTAGGACTACTCAATGTGGCCCAGGGCCACAACAAGGAACAGGGCAGCAGCAAAACAGGACTACAGCCCATACAGGGGCATTGCAGCACCCTAATAATGCCATCACCATGGTTACAGCAACAGCCTCTGTGACAGTGGCAGTGCACCCCAGTTTGCCGGGGTCATACCAGGGTTACATGCATGAAGGGTTTGAGGATAATGAGTCAGACTCTTTTAATGACTCTAAGAGGACTTCTCACACCTATGGAAAAGCCACACATTATAAGAAAGACTCTTTGGAACTTCAAGATCTGAATTCCACAGAAAAAGACCCACATCAAGCTAACCAGATGCTAG[G/T]TAAATAGCATTATATTTAAATCATCAAAACTAGACATTTGTATTTTTGCTTGTCGTGAAAAAACAACAACAATCAGCTCTCTTTATTGATCATAACTTATGTCAACCTTTTGCATGTGTTACAGGTTGTGCATGGAATCAAGCAGCCAAAGATTGCTAGACTGCTACCAGCCCCCACATCCTTTTGTCTGGAATCTCTGGCTGTTTTGGGAAGTTCCCAACCCCAGCCCTGTGTCTTTTATCTCTTTGAACTGTACATAGACCTCACACAGACAAGAGGATTTATTTTAATTATTAAAAAAGGTCTTTATAGACATTTATAAATTATATATATATATATATATATATATATATATATATATATATATATATATATATATACATACTAAAAGAGGGAAACTATTTTAAAATGTGCTGTATAACTTGTGTATTCTCTTGTGTAAAAGTCAGATGTATAAGAGGATTTGGAGGCCTTGTTCCCTCCTTTGTATAGATTATAAA
Associated Phenotype:
Not determined