Busch Lab

ZMP

LAMA1

Ensembl ID:
ENSDARG00000056043
Description:
laminin, alpha 1 [Source:HGNC Symbol;Acc:6481]
Human Orthologue:
LAMA1
Human Description:
laminin, alpha 1 [Source:HGNC Symbol;Acc:6481]
Mouse Orthologue:
Lama1
Mouse Description:
laminin, alpha 1 Gene [Source:MGI Symbol;Acc:MGI:99892]

Alleles

There are 10 alleles of this gene:

Allele Name Consequence Status Availability
sa13584 Essential Splice Site Available for shipment Available now
sa17699 Nonsense Available for shipment Available now
sa10397 Nonsense Available for shipment Available now
sa44203 Nonsense Mutation detected in F1 DNA Not yet available
sa24576 Nonsense Available for shipment Available now
sa44204 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa37969 Missense, Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa13584
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078414 Essential Splice Site 293 2660 6 67
ENSDART00000108598 Essential Splice Site 293 2680 6 63
Genomic Location (Zv9):
Chromosome 24 (position 43476115)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 41815541
GRCz11 24 41715594
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCATCTGCTATGGCCACGCCCAGAGCTGCCCCTGGGACCCTGTTACCAAG[G/A]TAACCGTYAACACATTGKAGCTGAAGCTGCCAATCAAACTATAGTGTGCC
Long Flanking Sequence:
AGCCGTCTGTCCATTAGCCATTAGAGTGTTTGAGCTGCTGAAGATGATGTCAGCATAGACTAAGAGCATTATAGATGTGGAGTTCTAGATATATTTTCATTTAATATTCTGCATTAATATTTAATACCTTTCTTTAAATAAATTGGAACTATACCTAAATTCAATTTCAATGATTAGTGATAAGAAAGCTGTTCAAACTTATCGAAGTTGTGCTGTGTGCTTAATATTTTTAATATTTCATGTGTGTTTCTTTGTTTTTTTCTAATCTCTTTCTTACTATACTCAATTTAATTTCTTACTATAGTTCAGTTTAGTTATTAATTTCTTAATTGTAAAATTATTTTAGGGGGTTACGATAGTGTATATTAATATCTTCTGAATGAATAACTGTATTATGGTCTGTTTTTCAGTATTATTACTCCATCAAGGACATCTCAGTGGGCGGGATGTGCATCTGCTATGGCCACGCCCAGAGCTGCCCCTGGGACCCTGTTACCAAG[G/A]TAACCGTCAACACATTGGAGCTGAAGCTGCCAATCAAACTATAGTGTGCCATTAGCCCCGCCTCTCTAAACAAACAAATACATTAATGAAGTATAAATACAAAATAATCTTTGGTAACAAGTTTAAAGGGTCGCGAAACACCCAAACACATTTTTGACATGTTGACAGTCATATATATATATCTGTGTCTCACGATGCTAAAAACAAAAAAGTGAAAATTGGTTGTTTTTGGGTTATTTCGAGCAAATTTATTCTTCTGGTTTGAAAATGAATGTTGAAGCTGTGTCAGAGTGATTAGATCCTTGTGTGTGTATTCCAGCGTGGAGACTGGATGTCAGTACAGGCAAGTACTACGTGACGTCTTTGAGACTTCATTATTAATTCATGACAAAGACTTGGTTTGAACCAATCAGCGTGCTCTATTGTGAATGAGGCAACCCAACCTCATTCTGGAAACGTAGCCCCGCGGACGTTTCTGGAGACCGCGATTTACGTGGGCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17699
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078414 Nonsense 436 2660 10 67
ENSDART00000108598 Nonsense 436 2680 10 63
Genomic Location (Zv9):
Chromosome 24 (position 43481786)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 41821212
GRCz11 24 41721265
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTGTGATGTTGTTTGTGTCGTGCAGGTCTGTCTCCAGGTCAGTGTGTGTG[T/A]AAGGAGGGTTTTGCGGGAGAGAAGTGTGACCGMTGTGCGTTCGGCTTCAG
Long Flanking Sequence:
CCAAAACTTACCCCTGTCAGATTTAGGTGGGGGAATAATAATAATCTTCATCATCATTAATAAAAAATATGAAATCTAAACACCAAACACCAATCGCACAACTTCTGTTCAACAGCTCCATTTATCACAAAGCCTCACACATATTACAAAACTCAGTAATTTTCAGAGGTTACATATCTGAGCTTTTCAGGATGTTCAAGATGGCTTTCAGCTCCAGAAGTGCTGGATTCAGCTGCTCATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTCAGGTGTCTCCGTATGCAGAAGAGCCGTGTGTGGAGTGTCAGTGTGATATGAGGGGTTCAGTGAGTCCTGTGTGCATCAGAGATGATAATCACGCAAACCCAGACGCAGGTAGAGTATCGCCATCTGTTTCTGCAGATTCAGCATGAGTGTGTGTGTGCAGTGTGTGATGTTGTTTGTGTCGTGCAGGTCTGTCTCCAGGTCAGTGTGTGTG[T/A]AAGGAGGGTTTTGCGGGAGAGAAGTGTGACCGCTGTGCGTTCGGCTTCAGAGATTTCCCGGTGTGTTCTCGCTGCGAGTGTAGCCTGGATGGGAGCCACAACACCGATCCCTGTATGGAGTGTGTGTGCAAGGTACTAAAACACACACACACACGCACACACACACACACACGTCACTCACAGGGTTGGGTAATAAACTTTAAAAAAAAAAAACTTTTTAAAAGTTTTTTGTTTTGATTTTGTTTTGTTTTATTTTATTTTGTGTATTTTTGTTTTGTTTTTGTGTTTTTCTTTTGTTTTGTTTAGTTTTTTTTGTTTTGTTTTTGTTTAGTTTTTTGTTTTGTTTTTGTGTTTTTTTTTTTTTTTTTGCTTAGTTTCTGTTTAGTGTTTTTTGTTGTTTTTTGTTTTGTTATGGATTTTAAAAATTTAGATTTTGTGTTTTTTTGTTTAGTTTTTTGTTTAGTTTATTTTTTGGGTTTTATGTTTTCTCTTTTGTTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10397
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078414 Nonsense 675 2660 14 67
ENSDART00000108598 Nonsense 675 2680 14 63
Genomic Location (Zv9):
Chromosome 24 (position 43487513)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 41826795
GRCz11 24 41726848
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGAGAGACGAGCTGATGACRGTGCTGGCGGACGTTGCTGCGCTCAGGGTT[C/T]GAGCCGAGCTGGARGACAGCGCTGAGGGAACGCTCAGGTCAGACACATGC
Long Flanking Sequence:
GGGCGGGGCTTTCCCCCTCTGATGACATGTACAAAGGGAGAATGTCAATCAAAGTGTTTCATTCATCAAGTCTGATTATATCAAACACAATTAATACATGTTGAGGCTGTTGGAGATATTCACACACTGCTCACACACACACAACTTGGGTTAAACATCACATAAATGTGACTTCTGCATTATAAAATAGTACTTAATTGTGTTTATATCACTATAATGTGGCTGTGTACACACAACAAACAGCTATCCAAATGTTGGTTTTGCATAATAGGAGCCCTATAATATCATGTGTGTGTGACTGAGTGTGAATGTGTGTGTTACAGGGTAACGGGCGCACGCTGAGGCAGGCGCAGTCGGCTCGTCTGCTGCTGAACGCTCACACACACCAGCGTGTGTTTGTGCAGATGCTTCCGCAGATCTTCATAGACTCACACAGCGGCAGGAGCGTGCAGAGAGACGAGCTGATGACGGTGCTGGCGGACGTTGCTGCGCTCAGGGTT[C/T]GAGCCGAGCTGGAGGACAGCGCTGAGGGAACGCTCAGGTCAGACACATGCAGAACATATCCTGATGAATGCTTGACTCTGATTGGCTGATGATAGACAATACAGTCTGTACACTATAAAAACAATGGAAACCTATGGAAGGTCCCGACAATTCACAAAAACAAACCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTCGTCCACAGGTTGAGTCACGTGTCTTTAGGTGTTGGAGACTCAAACTCCGATGTGTCTAAAATCTCTCTAGATGTGGAGCACTGTGAGTGTCCGTGGGGGTATTCAGGCACTTCCTGTGAGGTAACAAACCACTTCCAGGTCACTTCATCAGTATTTTGCTGTATCCCAATTCGCATGCTGTCCATTTTAAATATTCAAGAGTTCACACTTAGCTGATGATTGATTATAAAGCTTGTTTGGCATGCTGTCCCGGGAGAGAGCCCTGAGCTCATGATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44203
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078414 Nonsense 1017 2660 23 67
ENSDART00000108598 Nonsense 1017 2680 23 63
Genomic Location (Zv9):
Chromosome 24 (position 43498099)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 41837438
GRCz11 24 41737491
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCGCACACACTCATGGGAACTGCAACGATCAGACGGGCGAGTGTATCTG[T/A]CCTCCACACACACACGGGCTGAAGTGTGAACAGTGTGATGAAGGTCACTG
Long Flanking Sequence:
GGTCGGAAAAACCTGCGACCGCTGCCAGGTATGACAACTCGTGTGCTGCACATAAAACATTACAGTGTGTCATAATTCTCCTATTGTAGTTCTGCTTTAGAAAGAGCCTTACAGTTGCGTGTGTGTGTGTGTGTGTGTGTGTTTCAGGAGGGTTATCACGGTATTAACAGTGGTGAAGGCTGCAGACCGTGTGAATGTAACCAATCAGGCGCTCTGTCTGCGTCATGTGATGAGGAGGGGCGGTGCCAGTGCATAACTGGGGTAACGGGTGACAAATGTGATCGATGTCACCATGGATACTACAACTTCAAAGAGAACGGATGCACAGGTAACACATGCGCTATAGGGGAACTGATCAACTAAATTGGCCTTAGGATAGTCTAAATAAGAATGACTCTGTACTGTCCAATGAGTGCTCAAAGCTGATTTATTGATCCTCCAGCATGCGACTGCGCACACACTCATGGGAACTGCAACGATCAGACGGGCGAGTGTATCTG[T/A]CCTCCACACACACACGGGCTGAAGTGTGAACAGTGTGATGAAGGTCACTGGGGTCACGACGGAGTGTCCGGCTGTAAGGTACGACTCTACAAAGCCATGTGTGTGTTTGATCATGTGTGTGTGTGATCATATATGTGTGTGTGCCATCATGTGTGTGTGCGTGTGTGGGTGTGTTTGTGTGTGTGTGTGTGATAATGTGTGTTTGATCGTGTGTGTGTGTTTGTGTGTGTGTGATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTCTAAGATGCAGTGTGTAATTGATGATTAATGCTGATGTTGTGCTCAGGATAATGTGGGCGGCAGAGGCTGTGACGAGTGTAAGAGCGGCTCCTTCGGGCTCTCGGCCCTCAATCCGGCCGGCTGCAGCCCCTGCTTCTGCTTTGGCCTTTCAGACGTGTGTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24576
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078414 Nonsense 1203 2660 27 67
ENSDART00000108598 Nonsense 1203 2680 27 63
Genomic Location (Zv9):
Chromosome 24 (position 43500489)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 41840825
GRCz11 24 41740878
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAACTCTCTCTCCTCACCGGACCGTATTACTGGAGACTCCCACAGAAATA[C/A]AACGGCAACAAGGTACAAATACACAACACACCCACAGAAACACCAGGGTA
Long Flanking Sequence:
TACATATGTCAAAATAGTAACATCCTAAATTAAATGCAAACAATTCACATTTATTTATAGCATGCATAAAAACAGTTATATAAATACACATCTCAAAATAGTAACATTTTAAATGCAAACCATATACATTTATTAATAATATGCAAAAAAAGTTTATTCTTAAATGCACATCTCAAAAGAGTAAAATGAAAAATAGATGCAAACAATATGCATATACATGCATGCATATTGTAATAATTATAAAAACTACTATAAAAATGATGTTGCTGAATGAATCGTGTGTGTATTTGACTAGTAATAATCATCTATTAATCGTGTGTGTGTGTTCAGATTGTTCTGGGTTCATCTCCGGCTCTGCTGCGTGTAGTGTCTCAGAGTGACCTGCAGGGGACGCTGGAGGGCGTTTATTACAGCGATGACGAGATGCTGCTGGACGTGGATCAGCTCAACAAACTCTCTCTCCTCACCGGACCGTATTACTGGAGACTCCCACAGAAATA[C/A]AACGGCAACAAGGTACAAATACACAACACACCCACAGAAACACCAGGGTACAACACCATAGATATACCATGGTAGTACAGTTTGCAGAAACAGAGACAGAGAGGGCCAATAGTATCTGGGTGCAGACTTGGGTTTGTGAGCTGAGACTGTGTATCTCAGATTTGCTATTAGAGCTTAGAGATCCCAAAAATTAAACCTAACCCTATCCGAGCCCGTGCACCCCATGCCCAAGCCCGACCCAGTCTCAGACATTAACTGTAATTAAGAATTAAAAATTAAAACAGATGTTCTCAGCTACAATTCTGAGTCATTTGAACTGCAAACATGAATTTAAGGGTGACAAATAAGGACATTGAAGGCTGACTATCATCCTGTCTGCATACCTGTCAACCCTCCCATGTTTGCAGGGATTCTATCCTGTTATCATCCTGTTTTCAAGAGTTCACACTTAGCTAATCAATAATCAGATAATTGATAATCAGCTAGATAATCAATAGAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44204
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078414 Essential Splice Site 2300 2660 57 67
ENSDART00000108598 Essential Splice Site 2302 2680 55 63
Genomic Location (Zv9):
Chromosome 24 (position 43534657)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 41881892
GRCz11 24 41781945
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGTGTGTGTGTGTTTTCCTGCAGTGAAAGAGGGCTATAATGTGGGCTCA[G/T]ACGTGACGGTGAGTCTGGAGTTCCGCTCCACGGCGCCGGATGGTGTTTTA
Long Flanking Sequence:
GTGCTGTTTTTTAGCTATATTTATACTAATATGTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATTAAGCAGATCAATCTTATATTACTGATAAATAACATATGCATATTAATCAGGGCGGTAAAATACATATTTATTAAACAATCCAGTTTACACAATAGACACTTCTTGATTCTGTAATCGTATTACTTTTCACAAATAGATCATCATAGAAAATCAGCAGCTGACCTATCTAAATTAACAGGGGTAAAATTACATACCTCTGTTCATTGAATGGAGACAGTACACTTTATAGACAGTAAACTAATGAAAGAAGAGAATTAGACATGCCGTGCTTTCATTCAAAATAAGAGTGCTTTCAGATCTTGAATGTGTGTGTGTGTGTGTGTGTTTTCCTGCAGTGAAAGAGGGCTATAATGTGGGCTCA[G/T]ACGTGACGGTGAGTCTGGAGTTCCGCTCCACGGCGCCGGATGGTGTTTTATTAGGAATCAGCAGCACTAAAGTGGACGCCATCGGCCTGGAGCTGCTCAACGGACAGGTCAGTGTTCGCTCTACAGTGTCCAATAAACAGCGTTCCCACCACGGGTCATTCATTTCTGGAGGTTTAAAAGGTTTTTCCACACATTGAAAGTCAGGAAATTTGTGTTTTTATTTTTATTATTAATTGTCATTTTACATTTTTGTTTGTCGCATTAAATTTTAGTTTCCATTTATCAAAATGCGATTTTTTTCTAAAAACGTAAAGTAGATCCAGCAGGTTTTTATCTCAGAATTAAGTTTATCAGCCCGATTATCAGTATTAATAAAAATTAATGGGCATGATCAATAAACACACATTGATGGTGTTGAATAACGTGTTTCTCCTCATCTCAGGTGGTGTTTAATGTGAATAACGGTGCGGGCCGCATCTCGGTGAGCAGCAGGAGCAGCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37969
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Missense, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078414 Nonsense 2647 2660 66 67
ENSDART00000108598 Missense 2650 2680 63 63
Genomic Location (Zv9):
Chromosome 24 (position 43542645)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 41873695
GRCz11 24 41773748
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGATATGGACAGCTGTTTGCTGGAGCCGCGGCCCAGACGAGTACTGCTG[C/A]CTGATGACCCGGAGCCGACCTCTGACCCCGACACACGACCTCTGACCCCT
Long Flanking Sequence:
TCTACATCGGCGGCGTTCCTCCAACAGAGGGAGACACACACACACTCACACCTGCCTTCTACGGCTGCATCAGGAACACTGCGGTCGACGGCATGTGAGTCTCACACACACACATACACACACACACAGAGACACACTTACAGTCATGCACACTTACATTCTAAGACACACACACACACATACACACATATAGAGACACACATTATCACATACACATACATAGAGACACACACACACACATTTAGAGACTAAACCATGTATGCAGGTGTGCGTGTGTGTGTGTATGGTATCATTACATCTGAGCAGCTGATGTGTCTACTATTGTAAAAGAGTTGTGGGTCTGTGATGTTCTGCTGGTCTCCAACTTTTATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCAGGTTGTTGGATCTGTCCGCTGCGCTGCGCTACGAGCAGGTGGATATGGACAGCTGTTTGCTGGAGCCGCGGCCCAGACGAGTACTGCTG[C/A]CTGATGACCCGGAGCCGACCTCTGACCCCGACACACGACCTCTGACCCCTGCAGCAGCGGAGCTGAGTGCGCTCACACCAAACAGCGGCAGCGTGAGTCTCACACACAACACAAATGATCTATCAATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCCATCCATCCATCCATCCATTTATCCATCATCCATCCATCCATCCATCCATCCTTCCATCCATCCATCCATCATCCATCCATCCTTCCATCCATTTATCCATCCATTTATCCATCCATCCATCCATCCATTTATCCATCATCCATCCATCCATCCATCCATCCTTCCATCCATCCATCCATCATCCATCCATCCTTCCATCCATTTATCCATCCATTTATCCATCCATCCATCCATCCATTTATTCATCCATCCATTCAACCATTTATCCTTCCATCCATCCATCTATTTATCCATCCATCCATA
Associated Phenotype:
Not determined