ZMP

ENSDARG00000057107

Ensembl ID:

Human Orthologues:

ARHGEF6, ARHGEF7

Human Descriptions:

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 [Source:HGNC Symbol;Acc:685]
Rho guanine nucleotide exchange factor (GEF) 7 [Source:HGNC Symbol;Acc:15607]

Mouse Orthologues:

Arhgef6, Arhgef7

Mouse Descriptions:

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 Gene [Source:MGI Symbol;Acc:MGI:1920591]
Rho guanine nucleotide exchange factor (GEF7) Gene [Source:MGI Symbol;Acc:MGI:1860493]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa44165	Nonsense	Mutation detected in F1 DNA	Not yet available
sa30117	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa44165

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000079705	Nonsense	144	343	4	10

Genomic Location (Zv9):

Chromosome 24 (position 30618507)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	24	29647598
GRCz11	24	29635749

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TATTCTAGGCCGTTTCCCACAGAAGAGAGTGTTGAGGATGAAGACATTTA[T/A]AACCATCTTGAGGATCTGATAGAGTGAGTCATTTTTCTGTGTCCACTGAT

Long Flanking Sequence:

TATTGTAGAAGATCACACATCTATCAGCCAATCAGATTCGAGAACCAGACAGAACTGTTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGAACACACAACAATATGTAATATATTAAAATCAGTTATTATGGATTGTATGAATAAATGTATTAATAAGTAGCAGTGTAGCTCCAATATTGACTTTGAATATACTCCTTTGTTTAACAAATGGTGATAATTTAATTTTTATTTTTCTCTTAGGTTATGGACACGCTGTCCAAACTCTCTCATACGCACATTGCACAGCAGACTGGAATAAGGTATGTTTAAAAAGAGCAAGTGAATTATTTCCACTTTTATAAGAGAGCTGATAAATAATGTATATTTTGTGTCCGGGTCTTTCTATTCTAGGCCGTTTCCCACAGAAGAGAGTGTTGAGGATGAAGACATTTA[T/A]AACCATCTTGAGGATCTGATAGAGTGAGTCATTTTTCTGTGTCCACTGATGCTCTTCTTCTGCAGAAATGAGATGATGTTTGAACCCACAGCTCACTGTATGATACTTTGTCTGTTTAGGGAGCTACAGGAGCCTCGGGCTTCTTAATGCATTGATGTTGACAAATTGAGTCATTGCACATACTGTACATGCTGTTCCCTGTAACAGGGTCATTAACTACAACCAAATATAAAATTTAAAATGTTTAAAATTGAACTGTTGTTACTTACTGGGAATATTTAAATATATATAAATATAATAAAATTTACACTAGCTGCTAGTCTCATTTTCATTTAATATATCTTCAATGTGAAATAATACAAATTTAAAAAAGCCATATAGACATAAAATGATAAAAAAATGAACAAAAAAAAAACATTTATTTGCAAAGAACATGGATTTAAAAGGGTTATTGAAATGTAAAAGTTACAAGTAACGCTTTTCAGATAAATACTGTTTTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa30117

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000079705	Essential Splice Site	277	343	8	10

Genomic Location (Zv9):

Chromosome 24 (position 30605887)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	24	29634978
GRCz11	24	29623129

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ATGCACAACGCCACAAACCTCTACCAGATCTTCATCAAATACAAAGAAAG[G/A]TGACAGATTTGTTCTTCGTATCTCTTTAAGAGTGAAATCTGTCTCATATG

Long Flanking Sequence:

TAGTTACTATGTCCAGTTCCAGTTACTAGTTATGAAATGATGGTGCATTTTTATAACGGTTCAAATCGTCATTTTAATTTTAAATGCATTTTTATGTGCATATTTTTATATATTCATTGTAATTTCCATGATTAAACCATAATAAATTTAGCTTGACACACCAGACATACATCAAATTGCAAACAAAGTGCTTTAGTCATAGCAACTTTCTGTGCTCTGTCTTTTTTTCCCTCCACCCACAGTTCTTTATGAAGCCTCTGGGACAGTCGCTGTCCAGCGTGGAGATCGAAAAAGTGTTCATCAACATACCAGTGAGTTTATGAAGCACAGGCTTTAGCATAAATCCAGCGTATTAGTCCTCGTCGCTTCATATTTTCATATTCTTCATCACATCAGGATCTTGTGAAAGTGCACACGAGTCTCCTGAGGGAAGTGCAGGATTCAGTGCTCATGCACAACGCCACAAACCTCTACCAGATCTTCATCAAATACAAAGAAAG[G/A]TGACAGATTTGTTCTTCGTATCTCTTTAAGAGTGAAATCTGTCTCATATGTGTTTGCTTTACTCTGCTATAGATTAGTCCTGTACGGCAAATACTGCAGTCAAGTGGAATCTGCCATTGCATGTCTGGATGACATCTGTAAGAACAGAGAGGACGTCCGGCAGATGCTAGAGGTGAGATGTTCAAAAAATGATGTGGTAGTGTTTATTTATTATGAAATTTTAAAACTATATGTTTTTTTTAAGGATATTTTAATTGCTGAGAAAACTATTATAATATAATTCTGAAAATTGAATTATTATTCATAACTTATAATTGAATAATTATAACTGAAATAGATGTGGCCGTGTTTATTTGCTGTGAAGCGCTGCCCCCTGGTGGTTGTGAACAGCACTGTTTTGAAACGTTTATTTATTTTTTTGTAAATGTAAAATAATATATGTATAATATACCAGAAATAAAATGTTTATAGAACTGTTTGTATGTTTATATTTACATCAT

Associated Phenotype:

Not determined