ZMP
si:dkey-108d10.2
Ensembl ID:
ZFIN ID:
Human Orthologue:
MAP3K15
Human Description:
mitogen-activated protein kinase kinase kinase 15 [Source:HGNC Symbol;Acc:31689]
Mouse Orthologue:
Map3k15
Mouse Description:
mitogen-activated protein kinase kinase kinase 15 Gene [Source:MGI Symbol;Acc:MGI:2448588]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa13317 | Essential Splice Site | Available for shipment | Available now |
| sa37904 | Nonsense | Available for shipment | Available now |
| sa24513 | Essential Splice Site | Available for shipment | Available now |
| sa44153 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa44154 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa13317
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006615 | Essential Splice Site | 157 | 1331 | 3 | 29 |
| ENSDART00000143099 | Essential Splice Site | 157 | 1321 | 3 | 29 |
Genomic Location (Zv9):
Chromosome 24 (position 26715453)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 24 | 25773810 |
| GRCz11 | 24 | 25918851 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCTCTCTTCTCTTTTCTCTTGCATAGGACATGGTGGCACAGAAAAACACA[G/T]TAAGTGWCAAAAGACTCCTTGCAGGACTGGTAATCCRATGAGGTTTGGYG
Long Flanking Sequence:
GATAAGTTATGTCTTCAAGCCTGCAGGCTCATATTCTCACATTTAGTATCTCTGTCATCTGAACAAAGAGGCCGCCCACCACTAGGCCCTGACCTACTATTCTGAGTCTAGGAAGGAGTTTATCTTTTCTGGGCACTGGACAGTAGAGCTGCCAGAACAACACGCACTGTTTTCAAGCAAAGGCATGCAGTCAGTCCCAGGACAGCTGCACATGGCCACGTTGCACACAGAGACATTGGAAGGCATGTGTTCTTCTGGCAAACTGTAACAATGACAATCACGCTTGGGGAGAAGCGTCACGCGATCCACTTGTGTATTTGTTAACATGTCCAACTGATTCATTCCCTATTAATAATGGAGTGAATGGCATTACACTGCAAGACGGTCTTGTGATTGATATTATCATGTGATATAAAAAAATACATGTTGCAATATTGCAGTTGAGTAATTTCTCTCTTCTCTTTTCTCTTGCATAGGACATGGTGGCACAGAAAAACACA[G/T]TAAGTGTCAAAAGACTCCTTGCAGGACTGGTAATCCAATGAGGTTTGGCGTCTGTTGTTGGTGTGCCAATAGCTTTGTGTATTAGACTATTTTTGAACATCTTATGATGACATACGTTTACATGCTCATGGCCCTAAAATAAACCCACCACTGTGAGCAGAAGCTGTATGCAAGAGTTGTATGAGCACAGAAGGTTCTAGTGTGTCACTTTGAAGACTGGTGCTGGTCCAGAAGAGTTCATAAGGGTTGTGAAGGTGTTGTGGTCATTTAAGTTAGTGGGTGTTAGTGGTTTTGATAAAAAGAGAGGGTCGTTGTGTGCTAGACTTTAAATAAATGTCTTATTGAGCAACTGGTGAAAAGAAGCTGACCTTGATGGTGATTTATAGCTGTGAAATGATCCAGTACACTTTTCAACATTTTGTGGATAGATGTGAATTTCTATGTTCGCTTTCACCTTCAACTATACTTTCTCAGCTGAAACGAGTAGTTCACTCAAACAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa37904
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006615 | Nonsense | 199 | 1331 | 4 | 29 |
| ENSDART00000143099 | Nonsense | 199 | 1321 | 4 | 29 |
Genomic Location (Zv9):
Chromosome 24 (position 26722075)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 24 | 25780432 |
| GRCz11 | 24 | 25925473 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGCCCAGCGCAGAGCATCAGAGTACATGCAGCCCAACTGGGACAACCTTT[T/A]AGGACCTCTGTGTGTCCCTTTGGTGGACCGCTTCGTCAGCCTTCTCAAAG
Long Flanking Sequence:
AAGTGAACGCACTTGATTGCACAAACAGCAGATCTGTGTGAAAAGGGGTGCACAGATGTACAAATCTACATTTGTTGACAAACAGTTTATTATTAATATTTACTTATCAGTATTATGGGAATTGTCGACCCGACAAATTTTATTGGACAAACATTTTTTAGTCTTACACCTTATCCAGAATATAAAAATACATTTAGATCATTTATTTTATTCATTATTATTGGAATGTGAAGAGACTTTCAACCAGCACAACTAAAAATGTTTCTAAAGACAATCACCTACTGCACCTTTAAGGCAACATGCTTTTTTGTTGTGTAGTTATTTTTACATTATCATGATATGAAATTGCATTTAAAACTGCTTTCTCCTTTTTTAGGCCTCTAGTGGGAACTACTATTTCATCCCATACCTGATGACACCCAACAACGAGTACTTGTGCTGTGAGAATGTGGCCCAGCGCAGAGCATCAGAGTACATGCAGCCCAACTGGGACAACCTTT[T/A]AGGACCTCTGTGTGTCCCTTTGGTGGACCGCTTCGTCAGCCTTCTCAAAGACATTCATGTCACGTCTTGGTATGACTGCTCATATTATGATCACCCCTGGCAGGATGCCAACTCCCATGCAGTGCTTCACAGATCCGTTACATGATGGTGTCATGTCATGTTTTGCTTAGCGTAAATCAAGCCAACACTACCTAATTTTAACCAAACAAATCATATAAAATACATTTTTATATAATGATTTCTTTTTTTGTTGTTAACATTGAATTACAGAGTTAAAATGGGATAGTTTACCCAAAAATGAAAATTCTGCCATCATTTACTCCCCCTTAAATGTGTTTCTTCTGTACAAAATGCTGATTGCTGGGACCCATGGACTTCCATTGTCCCTATTAAAGGAGTTGATGGTTGCCAGCAGCCAGCATTCTTCAAAATATCTTCTTTTTTTTCTTGAACAGATGAAAGAAACGCATAAAGGTTTAAAACCACAATAAATGATGAGG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa24513
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006615 | Essential Splice Site | 314 | 1331 | 7 | 29 |
| ENSDART00000143099 | Essential Splice Site | 314 | 1321 | 7 | 29 |
Genomic Location (Zv9):
Chromosome 24 (position 26725229)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 24 | 25783586 |
| GRCz11 | 24 | 25928627 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATCTCAGGAAAAAATGCATTTATATTTGTGTGTGTGTGTGTGCAAACTC[A/T]GACGAAACAGCCCTGGTGATCGAGAGCAGGCGCTGCGTGTGATGTTGCAG
Long Flanking Sequence:
ACAGTGCTTCATACAAAGATGCACTCCTGAATGACATCCGAAAAGCTCGAGATAAATACCAGGGTGAGGAGCTGGCCAAAGAGCTTTCCCGTATCAAACTCCGCATCGACAACACTGAGGTTTTGACTCAAGATATTGTCATGAACCTGCTTTTCTCCTACAGAGACATACAGGTATGGTGTAGAATAGACCAAAACATTTAAAATATCATTAATAGCTGTACTGCTGGTTTTAATGGGCTTTGGTGATGTGTTTTTTCAGGATTATGATGCTATGGTTAAACTGGTGCAGACCATTGAGATGTTGCCCACCTGTGACTTGGCCAACCAGCCCATGATTCAGTTCCACTATGCTTTTGCGCTCAATAGGTGACCACAAATCTGCATTGTGTGGTATATTTTTTCCTATTCATATGCTTGGCAAACAGACATTTATCTTATACGCTGATTTGATCTCAGGAAAAAATGCATTTATATTTGTGTGTGTGTGTGTGCAAACTC[A/T]GACGAAACAGCCCTGGTGATCGAGAGCAGGCGCTGCGTGTGATGTTGCAGGTTCTTCAATCGTGTGAACACCCTGCTCCTGACATGTTCTGCTTGTGTGGCCGCATATATAAAGACATCTTTCTAGACTCAGACTGTAAAGACACCAAAAACAGAGACAACGCCATCCAGTGGTGAGTGAGTTTAATGCACTGCTGGAAGCATACTGTTTTATGATGCTTAAAGGTCTTATAAGTAAATAAAAGAAGTCCCTTAGTTTGCTGAAAAGCAGTGACATGAAATTATGTAACTATCAAAAGCATTAAATGTATTTAAAACACACAGAACGTGAACAGTCACATTAAAGGGATAGTTTGAAAATTGAATTGCAAAAAAAATACAAATATTCTCTATTTACTTGAAATGTTTTTGAGATTTTTTTTTTCTGTTCAACACAAGATATTTTCAAGCAAGCTAAAAACTTGAAACCATTGACTTCCAAAGTTGGAAAAATAAATGCTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa44153
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006615 | Essential Splice Site | 597 | 1331 | 13 | 29 |
| ENSDART00000143099 | Essential Splice Site | 586 | 1321 | 13 | 29 |
Genomic Location (Zv9):
Chromosome 24 (position 26735735)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 24 | 25794092 |
| GRCz11 | 24 | 25939133 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATTCAGATGACTTCCAGATCTACTTCTCCACAGAGGACCAGTGCGGCAG[G/A]TTGGCATTCAATGACACCCATCACTTTGTATTATTTCTGTATGTGTATCA
Long Flanking Sequence:
TAAAGATTGTGTTTGCAACTATGTGAAATAATATTAGACAAACCAAATAGAAGTATTAGTAAAACTGAGAATGAACATGGAAATTAAATTAAAAATATAATAAAAAGATCTGTTACAAAAGGTTCAAAAATGTAAACAGTATCACAAATATGTAATACCACAGTAATAACACAGAATTTAAACATCTATTTTATACTGTACATTATTAATGATGTACTGTAACTTTTACAAAGTTTTTTTAATTAGAAAAAAATAACATAAATGTACCAACGTTTTAAAATGAGGGCATTCCTGATTATTACCCAGAGTCCTCTAGGACCTGAAACTCCAATCTTTTCATTTTAATATGGTTTATTAATAGTCTCAGAGATGTGAAACAATTTTTTCATCTTTTCGCTTCCCAGTATCTCAAAGTTTGATGAGCGCTGCTGCTTTCTGTACGTCCATGATAATTCAGATGACTTCCAGATCTACTTCTCCACAGAGGACCAGTGCGGCAG[G/A]TTGGCATTCAATGACACCCATCACTTTGTATTATTTCTGTATGTGTATCAAATCTTTGCTCTTCACCAAGGTTATTATTTATATGGCTGTCTCCTGTTTAAAGGTTCTGCTCAATGGTGAAAGAGCTCATCACAGATGGATCTGGAAATGCTGTTGAGCTGGAGGGCGAAGGAGACGGAGACACCTTGGAGGTGAGAGCTTCAAAGACTCAACTATTTGTTTCATAAAAGGATAGTTTACCCAAAATATTGTCATTTTCAAATTCTGAATCATTTACTTATCCTCCATTTGTTTCCAAACCTATTTGAGTGTCTTGCATCTGTTGAACACGAAAGAAGATATACTGAAGAATGTTGGAAAAAACAAATTATTGCCTTTTTTGATTTTGGTCCTACTATGGTTGTCAATGGCTTCTTTTTTCATCAATCTTCAGTGCATCTTGTTTTGTGTACATGAGTGCAACTAAGTGGACGTTTTTATTTTTGTGTGAACAGTCCCTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa44154
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006615 | Essential Splice Site | 671 | 1331 | 15 | 29 |
| ENSDART00000143099 | Essential Splice Site | 660 | 1321 | 15 | 29 |
Genomic Location (Zv9):
Chromosome 24 (position 26737564)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 24 | 25795921 |
| GRCz11 | 24 | 25940962 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCAATCAGGTGCGCATTGCCATCAAGGAGATCCCTGAGAGAGACAGCAG[G/A]TGAGAGACTTGAGTCAAACCCATCTAAAAAAATAACAACAACAGCTAAAC
Long Flanking Sequence:
ACAATCTTTTTTAATGTTCTATTTATGCAGTATGAAGCGAACAAAGTAGAATATCTGCAGATATAAATATATTATAGATAGTTATTTTGTAAAATATAAAAGCAGTATGCAGTATAATGTATTAATACTTTTCTTCTAAATGTTTCCTGACAAAATATTTTTAATTATTATAAATATTTTTTTATTAAAAAATCCTAAAAGGTGATCAATTAAAGTAAAAATTATTACAAAAGCAAAAACTTTTTGAGCAAATGCTTGCTGTTCTATTTTCTAGCCAGTCGACCAGTGCATCTATAGTAATGTTTAAATTCATGGAGAATCTCATATTGTTACATTGGTGTACTTGCATCCTGATTGGTCTTACAGTATGAGTATGACTACAATGAGAACGGTGACCGGGTGGTTCTGGGCAGGGGGACCTATGGAGTTGTCTACGCAGGGAGAGACCTGAGCAATCAGGTGCGCATTGCCATCAAGGAGATCCCTGAGAGAGACAGCAG[G/A]TGAGAGACTTGAGTCAAACCCATCTAAAAAAATAACAACAACAGCTAAACAAAAACAGCATAGAAGATCACCAGCATGCCAGCATGTTGTGTTTTGGATTCTGGTATTTTTATCAGGTGGTGATAGTTCATCCAAAATTCAAATTGGGGAATCATGCACTCACCCACATGTTTTTAAAACCTGTATGAGTTTCTTTCAACTATGGAACATGAAACATAGTTTTGAAATTTTTTCTTTTGCGTAACAAGCTGCAGTGTTGCTTGTTTTCAATTGTTTTTTTAAAATTACATGTACAACAGTTGTCTGTCATATGATTTTAGAAATGTTTTAACAGTCCTTTTATTAAGTTAAAATATGCTAAAACAAAAGATAAATATATTAGATAAAAATTATATATATATATATATATATATATATATATATATATATATATATATATATAACACATACATATATACATATATATTTTTTAATGGCTTAATTTATAATGAAAACAACTA
Associated Phenotype:
Not determined