Busch Lab

ZMP

cdk8

Ensembl ID:
ENSDARG00000016496
ZFIN ID:
ZDB-GENE-030903-2
Description:
Cell division protein kinase 8 [Source:UniProtKB/Swiss-Prot;Acc:Q8JH47]
Human Orthologue:
CDK8
Human Description:
cyclin-dependent kinase 8 [Source:HGNC Symbol;Acc:1779]
Mouse Orthologue:
Cdk8
Mouse Description:
cyclin-dependent kinase 8 Gene [Source:MGI Symbol;Acc:MGI:1196224]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa24494 Nonsense Available for shipment Available now
sa44131 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa24494
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007066 Nonsense 115 465 4 13

The following transcripts of ENSDARG00000016496 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 24 (position 22137979)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 21384857
GRCz11 24 21530031
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAGGGTCTGCGTGTTTTTGCAGCACATCATCAAGTTCCACAGAGCCTCT[A/T]AGGCCAATAAGAAGCCTCTTCAGCTGCCGCGTGGGATGGTAAAGTCTTTG
Long Flanking Sequence:
GTTGTTTCTTTAGATTTGTTCTTATTAATGTAACATGAGGACTAGTTCTCTCAACTGAATGATTTGTTTACAACTGATCCATTTATCCAAATATCTGTTTTTATTGTTAATCGATCATGCAAGTCTGCAGCAAAAGCAGAATGAATGAATAATGGCTGAGTTATAATTTTGTCCAAACTATTCTTTTAATGAGCATACTTTAAGTGTTTTGGTTCTGCGGGAGCTTTGTAGATGTCAGTCTCAGCGTGTGTTTTTGTGTGTGTGTGTTTGCTCCCTGCAGCTGCTGCGTGAACTAAAGCACCCCAATGTGATCTCACTGCAGAAGGTTTTCCTGTCACATGCAGACCGCAAAGTTTGGCTTCTCTTTGACTACGCTGAACATGACCTCTGGGTAACGTACAGTCAAACGCTCGTGTGCACTGAGATGTTTGTACACAGTTCGTCTCTTGCTGAGGGTCTGCGTGTTTTTGCAGCACATCATCAAGTTCCACAGAGCCTCT[A/T]AGGCCAATAAGAAGCCTCTTCAGCTGCCGCGTGGGATGGTAAAGTCTTTGCTCTACCAGATCCTGGACGGCATCCACTATTTGCACGCCAACTGGGTCCTGCACAGAGACCTGGTGAGGTTTTATTTGTGATAGTTTAAACCATTGTGTCTTTCCTAGATGTCTCTGATCAGTTTTATTTACGATCATGTTGCTCAAAGTGTAAGATGTGAGTTGAATATTTGTTAACTAGGCAGATTATTATAGGTAACCCATAACAAAATTTCCAGTATGGGGCAGCTTCAGTCACAAATGGACAACTGACATTGGAGAATTAACATGTTTGAAAAAAAAAATTGTTAAATTGTTTTAGAATATTATTAAAGGTTTTTTTTTTTTTAGCCCTTTAACTTTTAAATTTAACATTTAATCCTTTCAGTTGGGTAATGGTCGCTGCCGTTGTTGCTAGAAGTGATACAGCTGGAAGTTAACAAGAAGTATATATATTATTTAATAAATAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44131
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007066 Nonsense 458 465 13 13

The following transcripts of ENSDARG00000016496 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 24 (position 22146285)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 21393163
GRCz11 24 21538337
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCCAAAGCAGCATGGGATACTCCTCTACCTCCCAGCAGCCTCCACAGTA[C/A]TCGCACCAGACCCATCGTTACTGAGTCAGGCCACACCCCTCCGCTCACAG
Long Flanking Sequence:
ACCAGTGAGAAATAGAAGCTGTTTCTAAAATAGAAATTTCAGTTCTTGGTTTGGACAAAAGCTCCTTTTAGTATAGAAAATATACCTTCTATCGCATACCATTGCTTTTAGTTGGAAAACGGTGAAAATCAGCCTTTAGGCTCAATAGTCAGGCACATTTCATTCTGGCAACCTGCGCACGGATTTGCCAGAGGAGGAGCCAAATGAAAATCTGTTTTGATCCAGGAGTGCAGTACCTAGTTTAACCACTGGGTGTCAAACTTACATACTGTACTTTTAAAGTTTTTTTATTTTGGAGAACTATTCTTTTAAACAAACTTTATGCCCAATTTTTTTCTTTTCCACAATTGTTTTGGAAACCCAGTATGTCACCAACACTGTTTAATCTCTGTTTTTCAGCGCTCCAATCCACATGCTGCCTACCAGAACCCAGGACCAAGCACATCATTGCCCCAAAGCAGCATGGGATACTCCTCTACCTCCCAGCAGCCTCCACAGTA[C/A]TCGCACCAGACCCATCGTTACTGAGTCAGGCCACACCCCTCCGCTCACAGTGCCCAATAGGGAGAATGTACTTAGGGAGGAGGGTGTGGCCTCGAGCCAAACCTCCCTCTTTTACCCCACTGGGCGCTTTGCTGTGCAGCATTTCCATAGAGACACCGCAGGAACAGTAACCGTAAAGCTAACATAACAAAGCGTCACCCTATCATACAGCCGACATTATCCTCTGCTGAAACAAGGAGAAAGAAAAAATAATGAAATAAGTAGTGGGAATAAAAAAAGCTGATGAAAAACGGATATTTGTTCCATTGGTGATAGTTTGAGTGTTCGCTGCAAGTCTGTGATTAATAACACACAAAAAGAAAAACAAAAAAGCAACAAGCATTCTCAATATGTGGTACTGAACAGCTGCACTATGTAGTGAGACTGGGTTTTGGATTGGTTTGGTCCAATCTCTTTAGCTCCAGTCCTTCTTGCCCTCACTTTGAAAATCTGTTGGCCTC
Associated Phenotype:
Not determined