Busch Lab

ZMP

prpf4b

Ensembl ID:
ENSDARG00000040310
ZFIN ID:
ZDB-GENE-040426-2799
Description:
serine/threonine-protein kinase PRP4 homolog [Source:RefSeq peptide;Acc:NP_998614]
Human Orthologue:
PRPF4B
Human Description:
PRP4 pre-mRNA processing factor 4 homolog B (yeast) [Source:HGNC Symbol;Acc:17346]
Mouse Orthologue:
Prpf4b
Mouse Description:
PRP4 pre-mRNA processing factor 4 homolog B (yeast) Gene [Source:MGI Symbol;Acc:MGI:109584]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa6760 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa44101 Nonsense Mutation detected in F1 DNA Not yet available
sa37836 Nonsense Available for shipment Available now
sa44100 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa44099 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa30054 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa6760
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000106310 Essential Splice Site 16 1010 None 15
ENSDART00000140217 Essential Splice Site 16 1010 None 15
Genomic Location (Zv9):
Chromosome 24 (position 11278131)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 11365534
GRCz11 24 11505901
KASP Assay ID:
554-5176.1 (used for ordering genotyping assays)
KASP Sequence:
AAATGGCYGAWCTGGAAATGGATTTACAGAGTAAGCGACTGAATAACGGG[T/A]AAGAACACGTGCGTGGTGTAACACCAGCAATAAAGCATTTTAAAGTCTGG
Long Flanking Sequence:
AATAAATGTAAAACAATAGTTTATTTTATTTTATAATATATATATATATATATATATATATATATATATATATAAATTATTATTATTATTATTATTATTATTATTATTATTATTATCATTATTATTATTGTTATTATTATTATTATTACATTTATTGTACATTTTAGTTAGTATTTTTAATGTAGTTAGACTTAGCTTCCCAGTTCTTCACACAAATACCTAAGAAACTTACCTTTGGCCTATTTTTATGCAAGTCTGAAAACAAGGAACTATTAAAAGTAAATGATAAGAATGGATACTACATTTTGACAGCACGTTTCTTTTTTTTAAGTTTATGGAAATACTCTGTAGTTGTTGATACAGACACTAGAGAGCACACGCGTTCCTCTGCGCTCTGCTCCTTCTCAAAATCTCACTAAGGAAGAATAACACAGGGCCGCCGCTGAAGCAAAATGGCCGATCTGGAAATGGATTTACAGAGTAAGCGACTGAATAACGGG[T/A]AAGAACACGTGCGTGGTGTAACACCAGCAATAAAGCATTTTAAAGTCTGGAATCCGAATAGGTTGTTTAGGGAAAATTGTCGTTGTGTCTTTCTCGTGGTGAGCTACGAGGACTTTGACATCTAATTGTTCTATCATGCTAGTGTTAGCATGCTAATGCTAAGTTACCTTGCAAACGAAGTCACCCACCAAGATTCATTTTTAGAAATCATTTCGTTAAACTTAATAGATTCTGGGTTTTAAAACCTTGAGGTCTGACATTCGTTAGACAATCGGTTTCATACCCATTAAATTGCTCGTTTCATTATTTGAGCTTTAAGTCAGATATACACAAGTAATTTGAAAATAAACGCAAACAGAATAGCACAGTGCATAATTTAAAGATCCGTTAGATCCAAAACAACCGTCTGCAAAGTATTCTGGAGAATATTTAACATACAAATACTAAAATATTAAGCCTTATAACAGTGCATTGAATAAAACACTTTTCTGAGTTGGTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44101
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000106310 Nonsense 209 1010 2 15
ENSDART00000140217 Nonsense 209 1010 2 15
Genomic Location (Zv9):
Chromosome 24 (position 11269415)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 11356818
GRCz11 24 11497185
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAGAACACGTTCACCTAGGGACCAGATTGGTGGAATGGGTAGATCCAGA[C/T]GAGACTTGGACACCAGCAAACCAAGTGCTAAACAGCAAAGTCACAGTCAT
Long Flanking Sequence:
AGGGTGAGGAGGAAGTGGAGATGAATGGAGAGAAGCAGGACATCAGTTCTAAACATCACAGCAGCAAACACAAAAAAAAGAAACACAAGCATCGCAGCAAGCACAAAAAACACAAACATGCTTCTGAGGAAGATAAGAACCGCAAACGAAAACATAGGCGCAAACATAAAAAGCACAAGCGCAAAGAGGAAGCATCCTCCTCGGCCATCAGCAGGAAGGCTGAGGATGGCTCCATGTTACTAAGTAGTGCAAACCTCGATGACAAGGCACTTCTTGAAGATCTAGAGAAACAAAGGGCATTAATTAAAGCCGAGCTAGACAGCCAGATGATGGAGGGTAAAGTTCAGTCAGGAATGGGCCTGATTCTACAGGGTTACAATTCTGGCTCAGAAGAGGATGAAGAGAGACAAAGGGCACGTAATGGGGAACAACGGCAAAACAGTAGTGGGGGCAGAACACGTTCACCTAGGGACCAGATTGGTGGAATGGGTAGATCCAGA[C/T]GAGACTTGGACACCAGCAAACCAAGTGCTAAACAGCAAAGTCACAGTCATTCTCGAGAGAGAGCAGGAAGGGATTCAAAGCTTGAACGAGCAACAAAAAGTGCAAAAGAGACTGTTAAAGAGCGCAGCAAGTCCAAAGAGAAAAAGCGTTCACGGAGCAGGGACAAATCCAAGGATCGTGGAAAGAAGTCTCAGTCCCCATCTATAAGAAGGCACTCTGCAGACAGAAAACCAGACCAGAAAGGCCGTCCTGATCGGCGCTCCTCTCCACATATGGATGAAAAGCGTGAACAAGCTAGACAGAGATCAGACTCACAAGGGGGTAAAAGCCAGTCGCAAGGTTCTAAAGATGGGCAAAATGTGGGCCGATCTGAGAATGACAGAGAAAAGAGGCCAGGAAAATCTCCGTCCAAAGACCCCTCATCTGGGAAAGAGAATAGATCACCTCAACAACGGCCAGCTCTTAGCCCACAGCATAGACGCAGTTCCTCCCCACGCCAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37836
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000106310 Nonsense 238 1010 2 15
ENSDART00000140217 Nonsense 238 1010 2 15
Genomic Location (Zv9):
Chromosome 24 (position 11269328)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 11356731
GRCz11 24 11497098
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAAGTCACAGTCATTCTCGAGAGAGAGCAGGAAGGGATTCAAAGCTTGAA[C/T]GAGCAACAAAAAGTGCAAAAGAGACTGTTAAAGAGCGCAGCAAGTCCAAA
Long Flanking Sequence:
AGCATCGCAGCAAGCACAAAAAACACAAACATGCTTCTGAGGAAGATAAGAACCGCAAACGAAAACATAGGCGCAAACATAAAAAGCACAAGCGCAAAGAGGAAGCATCCTCCTCGGCCATCAGCAGGAAGGCTGAGGATGGCTCCATGTTACTAAGTAGTGCAAACCTCGATGACAAGGCACTTCTTGAAGATCTAGAGAAACAAAGGGCATTAATTAAAGCCGAGCTAGACAGCCAGATGATGGAGGGTAAAGTTCAGTCAGGAATGGGCCTGATTCTACAGGGTTACAATTCTGGCTCAGAAGAGGATGAAGAGAGACAAAGGGCACGTAATGGGGAACAACGGCAAAACAGTAGTGGGGGCAGAACACGTTCACCTAGGGACCAGATTGGTGGAATGGGTAGATCCAGACGAGACTTGGACACCAGCAAACCAAGTGCTAAACAGCAAAGTCACAGTCATTCTCGAGAGAGAGCAGGAAGGGATTCAAAGCTTGAA[C/T]GAGCAACAAAAAGTGCAAAAGAGACTGTTAAAGAGCGCAGCAAGTCCAAAGAGAAAAAGCGTTCACGGAGCAGGGACAAATCCAAGGATCGTGGAAAGAAGTCTCAGTCCCCATCTATAAGAAGGCACTCTGCAGACAGAAAACCAGACCAGAAAGGCCGTCCTGATCGGCGCTCCTCTCCACATATGGATGAAAAGCGTGAACAAGCTAGACAGAGATCAGACTCACAAGGGGGTAAAAGCCAGTCGCAAGGTTCTAAAGATGGGCAAAATGTGGGCCGATCTGAGAATGACAGAGAAAAGAGGCCAGGAAAATCTCCGTCCAAAGACCCCTCATCTGGGAAAGAGAATAGATCACCTCAACAACGGCCAGCTCTTAGCCCACAGCATAGACGCAGTTCCTCCCCACGCCACAGGGATCGACAGTCTAATCAACCCCGCTTCAGTTCTGTGGATCGAAGTTCCAAACTGAGCCATTCGCCATCTAGGAATAGGTCACTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44100
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000106310 Essential Splice Site 553 1010 5 15
ENSDART00000140217 Essential Splice Site 553 1010 5 15
Genomic Location (Zv9):
Chromosome 24 (position 11259433)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 11346836
GRCz11 24 11487203
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGAGGCTCTGATTGAGCAGAGACGACAGCAGCGGCTGGCTATTGTACAG[G/A]TAGTTCATTACATCCGTACTCATGAGACACACAAGCTTTCTTTTTTTTTG
Long Flanking Sequence:
GGGAACACCTAAATTCAAATTATAATAAGTGCCCAAACACATACTTGAATAAATGATCTCAATGAAAAGGCTTTGAACCATTGTGACAATGCAGCATTTAGTTGCTTTCATACTGACCTTTGGCCATCGGGCAATCCTTATTGTTAAGCCATGCAATTTTGTCATTTATAACAAATGTTTAGAGCATTTTAGAATTCTTTGAGAATGATCATTAGTACAGGAGTAAAAGCCACTATAATTTCAACTGCCATCATAGCAATACTTTAAAATATGTTAAAAGATAAAATAACTTTTTTATTGTGATAATTAACAAAAAAAAAAAACCTTTTAAACTTGTTTTACATAATTGTACTGCAACTATTTTTGAGAATTTAGTAGTTAATATATCATTGATCCATCTTGCTTTGTCAATGTTTAGGATGGAAGATTTTGATGCAGAAGAGGAGGATGAAGAGGCTCTGATTGAGCAGAGACGACAGCAGCGGCTGGCTATTGTACAG[G/A]TAGTTCATTACATCCGTACTCATGAGACACACAAGCTTTCTTTTTTTTTGAGAGAGATTATTTGATTATAAAATACTGTTCTCTCTTATATAGAAATATAAAGCAGGAAATGAGGACAGTAATTTGGGGTCCATGCCATCAGAGCCCAGCAGCCCTCAGAGTAGCTCCCGCAGTCGTTCACCCTCCCCTGATGACATCTTGGAACGGGTAGCAGCTGACGTTAAAGAATATGAGCGGGAGAATGTAAACACATTTGAGGCCAACATCAAAGCCAAGCACAACCTCATCGCTCAGGAGAAAGAAGGTGGTGTACTCTGAGAGTGTTTTCAGGAAGTGTTTCAGCACAACTGTTTGGAAAATCTGGGTATCGCAGAATGATGTTAAGTATCTATTACTTCATGTTTGACTATTTGCTGTCTTTTTTGCAGGAAACAACCCAAAGAAGCCCTCAGCACCTGACATGTTCACTGAGTCAGATGACATGTTTGCTGCGGATTTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44099
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000106310 Essential Splice Site 679 1010 8 15
ENSDART00000140217 Essential Splice Site 679 1010 8 15
Genomic Location (Zv9):
Chromosome 24 (position 11255985)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 11343388
GRCz11 24 11483755
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGAACCCCAACCTCAGGGACAATTGGACTGATGCAGAAGGATACTACCG[T/G]AAGTCCAAAGCTATGTTTTTTTGCAAAACCGAACGAGTTGAAATATGTAC
Long Flanking Sequence:
AAATATTTAAAAAAGAAAAAAAAAATCAAAGGGTTGCTAATAATTCTGATTCAACTGTAGGCTATATAGAAAACTTACTTTTTTTATAATAAACTAATTTTAATACAAATTTTAACAAGAAAACACCCTTAATGTGTTTGTCTTTATAAAGATTTTTATGGTAATGTTTACTTTCACCTTCTCATTTTACGGAAACTCCTGAGACAAATAAGTTTAATAATAAATCTATATAAAATGCTGCACTTCCTGCCACCTTTATTCAGCCCAATGATTTTTGGGACTTCTCTAGCAAGTTTTGTGCTCCAATGGTAGTATGATTAATTTGAACAGTCAGTCTCATGATCTTTTGCACCTAGTTACCAGTTGGCTTTTTGGAGTTATCAGAATTTTGTGTCTCTTGCATATCAGAGTGCCAGACTCAGGGCTGCAGGCATTGGCAAAGACTTTAAGGAGAACCCCAACCTCAGGGACAATTGGACTGATGCAGAAGGATACTACCG[T/G]AAGTCCAAAGCTATGTTTTTTTGCAAAACCGAACGAGTTGAAATATGTACAATTCATAATTTAAAGCCATCTCTTTTTAGGTGTAAACATTGGTGAGATACTGGATAAACGATATGATGTTTATGGATACACTGGACAGGGTGTGTTCAGTAATGTGGTCAGAGCTAGGGACACTGCACGTGCTGGCCAGGAGGTGGCAGTCAAGATCATTCGAAACAACGAGCTCATGCAAGTATCATACTAAATATCATCTATAATATTTTATATATTTTTTCTATATATTTTACCTGTTGTGTTGTTCAGTTCAGTGTAGTCCTAGCTTGTAGCAAGATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATATATATATATATATATATATATATATATATATATATAAAATTTTGGTAAATCCTTAATGTTGAGGTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa30054
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000106310 Nonsense 883 1010 13 15
ENSDART00000140217 Nonsense 883 1010 13 15
Genomic Location (Zv9):
Chromosome 24 (position 11246945)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 11334348
GRCz11 24 11474715
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAACCATATGATTATGGTATTGATATGTGGTCAGTTGGCTGTACCTTGTA[T/A]GAGCTATACACAGGAAAAATTCTCTTCCCTGGCTCCTCCAACAACCACAT
Long Flanking Sequence:
CAGTCAACAGCTCTTTCTAGCTCTGAAACTACTGAAACGCTGCAACATCCTCCATGCTGACATCAAACCAGACAACATACTGGTGAGTATCATCTGTATCAGTGGTTCTCTTTGGGGGGTGAACGTGAATTGAGAACCATAAATCTGTTTAGCCACTGAGCCAAAAGAAGGCTTCATTTCTTTACTCATGCTCTCTGTCTGCAGGTGAATGAGTCAAAGACTATACTTAAACTCTGTGATTTTGGCTCTGCATCTCATGTTGCTGACAATGAAATCACTCCTTACCTAGTAAGCAGATTCTATAGGGCACCCGAAATTGGTGAGTTGCGTTGTATTTGTGTTTCAGATGCCTGTTCTGTTGAACACTTAAACTGATTTTATGTGTGCTTAGTAACTTTTTAGTAACTATTGTTTTCCCTAAATCTTTTTTTTCCATCCACAGTTATTGGAAAACCATATGATTATGGTATTGATATGTGGTCAGTTGGCTGTACCTTGTA[T/A]GAGCTATACACAGGAAAAATTCTCTTCCCTGGCTCCTCCAACAACCACATGCTAAAGCTGGCCATGGATGTGAAAGGCAAGATGCCAAACAAGGTACTGAACCAGTGTTTTTTTAAACTTTTAAATCTTTTCTGGAAATGCTAGAGTTATGTGTGAACAGGGAAGTTCATACATTTCATACTGCTGTTGTACGTCTGTTTTTATATGATGTTTTATTTTTCATTTTTGTAAAGATGATTCGGAAAGGCCTGTTTAAAGACCAACATTTTGACCAGAACTTGAATTTCCTGTACATAGAAGTCGACAAAGTGACAGAAAGGGTAAGACTTATCTAATTTACTTAAATGCTCATTTCATTCCATAATACTGTATACACGACTGCTTGTTTTTATTTCCAGGAGAAGGTAACAGTCATGAGCACCATTAACCCCACTAAAGACCTTCTCGCAGACATGGTCGGAGGTCAGAGGTTACCTGAGGATCAAAGGAAGAAAGTCATG
Associated Phenotype:
Not determined