Busch Lab

ZMP

LOC556392

Ensembl ID:
ENSDARG00000059003
Human Orthologue:
FAM40B
Human Description:
family with sequence similarity 40, member B [Source:HGNC Symbol;Acc:22209]
Mouse Orthologue:
Fam40b
Mouse Description:
family with sequence similarity 40, member B Gene [Source:MGI Symbol;Acc:MGI:2444363]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa40212 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa20192 Essential Splice Site Available for shipment Available now
sa761 Essential Splice Site F2 line generated Not yet available
sa33370 Nonsense Mutation detected in F1 DNA Not yet available
sa20191 Nonsense Available for shipment Available now
sa441 Nonsense Confirmed mutation in F2 line Not yet available

Mutation Details

Allele Name:
sa40212
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081990 Essential Splice Site 423 810 12 22
Genomic Location (Zv9):
Chromosome 4 (position 4857675)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 4975856
GRCz11 4 4984426
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACTTTCTGGAGACCAGCAGAAACAAATTCATCGGCTTCACCTTGGGAAA[G/A]TGAGTCTCTGATCAATTCTCCCAGGCCACTAAGCTTATGAATCCATGATA
Long Flanking Sequence:
GTGACACACACACAGACACCCTCACGCTCTCTCTCATTCACACACACACACACAGACAGCACAAAGCTCTCTCTCATTCGCACACACACACACATAGACGGCAACAAATAAGCTAAATTTACACACGCATGCTCGTTCGCTCGAGAGTCGGAAGCAATATTGTTAGACCGCCCTCTCCCGTCCAAAATTACACCAGTTACTGATCGCTCCCGCACTTTATTCTGAAATTTATTCCCGCGCCGCAAGAAATCCGGTCGGGTCCCACGGAATCCAGACCTCTAGATGGTGGTTCATTCCCTAATAAATAAGGGACTAAGCCGAAGGAAAATAAATGAATAAATGTTCTGACCTCAATTGTTCACGTTTGTTTACTTTGCATATTAGAATCTATTGTTGTTGACTACAGTGGGTTATCGATTTCCTTCTTCCTGCAGAGAGAAAGACATCGAGCACTTTCTGGAGACCAGCAGAAACAAATTCATCGGCTTCACCTTGGGAAA[G/A]TGAGTCTCTGATCAATTCTCCCAGGCCACTAAGCTTATGAATCCATGATAAACTATTATAAAGGTCTCCTTCATCATCATTAAATCAATATACAGTTTTCTTTCTGATCTTATTTCAGTGACATCGACACTCTGGTTGGGTTGCCCAGACCTATACACGAGAGTGTCAAGACTCTGAAACTGGTGAGCATGGAAATACTTTTATTTTTTTATATTTTCGTATTTTACTAAACGTCAGAGGTTTATCCATGGCACATCATTATTAGTAGGAAACTCTACTGAAATAAATGAGGTGGTGATGTAAAATTGATGAACTCATGAATGCACTGTGAAGACATCACTGATGCGACATCAAACGACAGAGATAGCATTTGTTGTGAATGCTGCTATTATACATGTGTGTTTTTTGAAAGAAATGAATGTTTATGTTCATGAAGAACGCATTTGAGTGGATGGAAAGTGACAGAGGAGGCATTCGTGATGTAGATTTGTTGAAGTCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20192
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081990 Essential Splice Site 423 810 13 22
Genomic Location (Zv9):
Chromosome 4 (position 4857558)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 4975739
GRCz11 4 4984309
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCTTCATCATCATTAAATCAATATACAGTTTTCTTTCTGATCTTATTTC[A/T]GTGACATCGACACTCTGGTTGGGTTGCCCAGACCTATACACGAGAGTGTC
Long Flanking Sequence:
TTTACACACGCATGCTCGTTCGCTCGAGAGTCGGAAGCAATATTGTTAGACCGCCCTCTCCCGTCCAAAATTACACCAGTTACTGATCGCTCCCGCACTTTATTCTGAAATTTATTCCCGCGCCGCAAGAAATCCGGTCGGGTCCCACGGAATCCAGACCTCTAGATGGTGGTTCATTCCCTAATAAATAAGGGACTAAGCCGAAGGAAAATAAATGAATAAATGTTCTGACCTCAATTGTTCACGTTTGTTTACTTTGCATATTAGAATCTATTGTTGTTGACTACAGTGGGTTATCGATTTCCTTCTTCCTGCAGAGAGAAAGACATCGAGCACTTTCTGGAGACCAGCAGAAACAAATTCATCGGCTTCACCTTGGGAAAGTGAGTCTCTGATCAATTCTCCCAGGCCACTAAGCTTATGAATCCATGATAAACTATTATAAAGGTCTCCTTCATCATCATTAAATCAATATACAGTTTTCTTTCTGATCTTATTTC[A/T]GTGACATCGACACTCTGGTTGGGTTGCCCAGACCTATACACGAGAGTGTCAAGACTCTGAAACTGGTGAGCATGGAAATACTTTTATTTTTTTATATTTTCGTATTTTACTAAACGTCAGAGGTTTATCCATGGCACATCATTATTAGTAGGAAACTCTACTGAAATAAATGAGGTGGTGATGTAAAATTGATGAACTCATGAATGCACTGTGAAGACATCACTGATGCGACATCAAACGACAGAGATAGCATTTGTTGTGAATGCTGCTATTATACATGTGTGTTTTTTGAAAGAAATGAATGTTTATGTTCATGAAGAACGCATTTGAGTGGATGGAAAGTGACAGAGGAGGCATTCGTGATGTAGATTTGTTGAAGTCAGAATTATTAGGCAAGTTAGGGTAATTATGCAAGTCTTTGTATGATGATGGTTTGTTCAGTAGACAATTGAAAAGAAAATATTGCAGAAGGGGACTTATAATATTGAGCTTAAAATGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa761
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081990 Essential Splice Site 468 810 14 22
Genomic Location (Zv9):
Chromosome 4 (position 4856553)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 4974734
GRCz11 4 4983304
KASP Assay ID:
554-0667.1 (used for ordering genotyping assays)
KASP Sequence:
GGTCCAGATCAAGAGRGAGGACGAGCTCCAGCAGTGCCCCATGACTATGG[T/A]AAGTGCCTTASACACGTCATRCTTTTTATGCATTTCTTACTGKTCCATTA
Long Flanking Sequence:
ACAAAGTATAAAACTGCTTTTATTCTAGCCGAAATAAAACAAATAGGATTTTTTTCCAGAAGAAAAAAATATTATAGGAAGTACTGTGAAAAAAATCCTTGCTCTATTAAACAGCATCTGGGAAATATTTTTAAAAGAAAATTCACAGACGGGCAAATAATTCTGACTTCAACTGTGCATAATTCAGTTATTGTGAACATGCCTGAATAGTTATTGCTGAACTAAGAGTGAGTTATTGATGAAAACATTAATATACCATTTAATAAATGGATTAAATGAATAGGATTTGCCAGCTGTTCTGCCACCGATATATGCACGGTCTTGAATCCAGTGATTTAATGCATGCTCCACTGTGGCTCTTTCCGCCAATCATAGTTTAGATATGTGTCCTTGGTCACCATGGCAATTCTCTCTTTTGTCTCTGAAGCACAAGTATGTCTCTATAGCGGAGGTCCAGATCAAGAGAGAGGACGAGCTCCAGCAGTGCCCCATGACTATGG[T/A]AAGTGCCTTAGACACGTCATACTTTTTATGCATTTCTTACTGTTCCATTAAGCTGTCAATCAGAAGCAACTCTTTTAATTGGCCAGGGGGAGGAAGAGGTGGAAGAAACACCCACAGAGATTCTGTATTTGGGGATGTTGCCCAGCCTCTCTCAGTATGTAGTAAGTGACCACTATAATTATTTGATTTGATGAAGTTTATGCTGTCAGATGAATGTCAAAATAGCTTATATTTTCTGATAAAGAAATTGTACAAAAGGGGAAATATGTATATTTTGAATGCGTTGGTCAATATTCTACTCTTTGGCTCAATGCAGTTGAAGTCAGAATTATTAGACCCCCTGAATTATTAACCCCCTGTTTATTTTTTTCCTCCAATTTCAGTTTAACGGAAAGAAGATTTTCTTCAACACATTTCTAAACATAATAGTTTTAATAACTCATTTCTAATGACTGATTTATTTTATCTTTGCCATGATGATAATATTTGACTAGATATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33370
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081990 Nonsense 696 810 21 22
Genomic Location (Zv9):
Chromosome 4 (position 4846804)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 4964985
GRCz11 4 4973555
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATGATGCAGCTCTATGTCCTCAAACTACTCAAGATCCAGACCAAGTATT[T/A]GGGACGACAGTGGAGAAAGAGTAACATGAAAACCATGTCTGCCATCTACC
Long Flanking Sequence:
GAGAACGTGCAAACTCCACACAGAAATGCCAACTGACCCAGCCAAGGCTCGAACCAGTGACCTTCTTGCTGTGAGGCAAAAGCACTGCCTACTGCGCCACTGCGTCGCCCTATTGACTTTCATAGTAGACAAAAAAACACACAATAGAAGTCAATGGTTACAGTTTTCTAGCTTTCTTCAAAATATAAAAAGAAAGAAACTCAAACTGGACCAATGAAAGGATGAGTAAACAATGACAGCATGTTCAGTTCTGGGTTTATTATCGCTTTAACGTTTTCTGATTGATGTTAGTATAGTAATGTACACCTTTTTTTTAATGCTGCTTTGAAACCGCAGTTGTGAGAGTGCTGTACAAATAAATAAGAACTGAATTGATTTATTTCGTTTGCAGATGCTTGTGGTGTTCAAGTCTGCTCCTATCCTGAAAAGGGCGCTCAAGGTCAAACAGGCCATGATGCAGCTCTATGTCCTCAAACTACTCAAGATCCAGACCAAGTATT[T/A]GGGACGACAGTGGAGAAAGAGTAACATGAAAACCATGTCTGCCATCTACCAGAAAGTCAGACATCGACTCAATGACGACTGGGCATATGGAAACGGTAAAAGTCTGAGTTTTGTCTTGTCAGGGGTGTTGAGGAAAACACTTTAAGTTGGTATTAAACAAAAGTTGCTGTATTTTTCGATCTTGGTTTGAGCCCAGAATTTTTATTTCCATGCATCTGTATTTGAACATTTCTAAATGTTTCTTTGATTAAGCTAAAGTTATTCTGATTATTCCTGTACACAATGCATTCTTTCAAATAATTCTACATTCCTCCTACCAGATATTGACGCTCGACCATGGGACTTCCAGGCGGAGGAGTGTGCGTTACGCGAGAGCATCGAGAAATTCAACACACGGCGCTATGATAAGAATCAGAACAGTGAGTTTGCACCAGTGGACAATTGCCTTCAAAGTGTTTTAGGTCAGCGCGTGGACCTGCCCGAAGACTTCCATTACAGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20191
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081990 Nonsense 716 810 21 22
Genomic Location (Zv9):
Chromosome 4 (position 4846745)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 4964926
GRCz11 4 4973496
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTGGAGAAAGAGTAACATGAAAACCATGTCTGCCATCTACCAGAAAGTC[A/T]GACATCGACTCAATGACGACTGGGCATATGGAAACGGTAAAAGTCTGAGT
Long Flanking Sequence:
ACCTTCTTGCTGTGAGGCAAAAGCACTGCCTACTGCGCCACTGCGTCGCCCTATTGACTTTCATAGTAGACAAAAAAACACACAATAGAAGTCAATGGTTACAGTTTTCTAGCTTTCTTCAAAATATAAAAAGAAAGAAACTCAAACTGGACCAATGAAAGGATGAGTAAACAATGACAGCATGTTCAGTTCTGGGTTTATTATCGCTTTAACGTTTTCTGATTGATGTTAGTATAGTAATGTACACCTTTTTTTTAATGCTGCTTTGAAACCGCAGTTGTGAGAGTGCTGTACAAATAAATAAGAACTGAATTGATTTATTTCGTTTGCAGATGCTTGTGGTGTTCAAGTCTGCTCCTATCCTGAAAAGGGCGCTCAAGGTCAAACAGGCCATGATGCAGCTCTATGTCCTCAAACTACTCAAGATCCAGACCAAGTATTTGGGACGACAGTGGAGAAAGAGTAACATGAAAACCATGTCTGCCATCTACCAGAAAGTC[A/T]GACATCGACTCAATGACGACTGGGCATATGGAAACGGTAAAAGTCTGAGTTTTGTCTTGTCAGGGGTGTTGAGGAAAACACTTTAAGTTGGTATTAAACAAAAGTTGCTGTATTTTTCGATCTTGGTTTGAGCCCAGAATTTTTATTTCCATGCATCTGTATTTGAACATTTCTAAATGTTTCTTTGATTAAGCTAAAGTTATTCTGATTATTCCTGTACACAATGCATTCTTTCAAATAATTCTACATTCCTCCTACCAGATATTGACGCTCGACCATGGGACTTCCAGGCGGAGGAGTGTGCGTTACGCGAGAGCATCGAGAAATTCAACACACGGCGCTATGATAAGAATCAGAACAGTGAGTTTGCACCAGTGGACAATTGCCTTCAAAGTGTTTTAGGTCAGCGCGTGGACCTGCCCGAAGACTTCCATTACAGCTACGAGATGTGGCTCGAAAGAGAGGTTTTCTCCCAGCCCATTCAGTGGGAAGGTCTGCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa441
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081990 Nonsense 755 810 22 22
Genomic Location (Zv9):
Chromosome 4 (position 4846401)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 4964582
GRCz11 4 4973152
KASP Assay ID:
554-0294.1 (used for ordering genotyping assays)
KASP Sequence:
GAGGAGTGTGCGTTACGCGAGAGCATCGAGAAATTCAACACACGGCGCTA[T/A]GATAAGAATCAGAACAGTGAGTTTGCACCAGTGGACAATTGCCTTCAAAG
Long Flanking Sequence:
TTCAAGTCTGCTCCTATCCTGAAAAGGGCGCTCAAGGTCAAACAGGCCATGATGCAGCTCTATGTCCTCAAACTACTCAAGATCCAGACCAAGTATTTGGGACGACAGTGGAGAAAGAGTAACATGAAAACCATGTCTGCCATCTACCAGAAAGTCAGACATCGACTCAATGACGACTGGGCATATGGAAACGGTAAAAGTCTGAGTTTTGTCTTGTCAGGGGTGTTGAGGAAAACACTTTAAGTTGGTATTAAACAAAAGTTGCTGTATTTTTCGATCTTGGTTTGAGCCCAGAATTTTTATTTCCATGCATCTGTATTTGAACATTTCTAAATGTTTCTTTGATTAAGCTAAAGTTATTCTGATTATTCCTGTACACAATGCATTCTTTCAAATAATTCTACATTCCTCCTACCAGATATTGACGCTCGACCATGGGACTTCCAGGCGGAGGAGTGTGCGTTACGCGAGAGCATCGAGAAATTCAACACACGGCGCTA[T/A]GATAAGAATCAGAACAGTGAGTTTGCACCAGTGGACAATTGCCTTCAAAGTGTTTTAGGTCAGCGCGTGGACCTGCCCGAAGACTTCCATTACAGCTACGAGATGTGGCTCGAAAGAGAGGTTTTCTCCCAGCCCATTCAGTGGGAAGGTCTGCTGCAGGCCCAGTGATAGCAGTGATCATTATTATAAGACTTTCTTATTTAACCGACACAATTACTGTGGCTCACGATCGACACACAAACACTCGAAGCAATGAGGATCTGGCATTCCTGTTCTGTTATGAAATCTTGTACATAAAGATATATGTGTGTATGTGTGTGAATATAAGATGGTAATCTTCCTTTGGCAAATCTGAGAAGAGAGCATCTGGTACTTTGGGCAAACACAAATAGAATATATATATATATATATATATATATATATGAGAGAGAGATGGAAGGATGATATGGTCTTTTTCAATAACTGAAGCACAATTTAGGTACAATAACTGCACAAATACA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461