ZMP

ddx49

Ensembl ID:

ENSDARG00000012899

ZFIN ID:

ZDB-GENE-031030-3

Description:

probable ATP-dependent RNA helicase DDX49 [Source:RefSeq peptide;Acc:NP_938179]

Human Orthologue:

DDX49

Human Description:

DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Source:HGNC Symbol;Acc:18684]

Mouse Orthologue:

Ddx49

Mouse Description:

DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 Gene [Source:MGI Symbol;Acc:MGI:2136689]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa4404	Nonsense	F2 line generated	Not yet available
sa24887	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa4404

Status:

F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000007204	Nonsense	162	468	5	13

Genomic Location (Zv9):

Chromosome 11 (position 6960684)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	6868178
GRCz11	11	6878017

KASP Assay ID:

554-3504.1 (used for ordering genotyping assays)

KASP Sequence:

GTCTTTTGACAGATCATGGATGAAGCTGATCGTCTTCTGGAGCAGGGYTG[T/A]ACTGATTTTACTAAAGATTTAGAGGTCATTCTCAGTGCGGTGCCAGYAAA

Long Flanking Sequence:

TTTATAGTCTATTCAAGTCTATACAAAATGTAGCATTTCAATCAGAACCTATACTCATATGTTTGAGAAATAACAAAAATAGGAGCTTAATTTTAACCTTTATTTTACATCTGCAGAGTTGTGAGAAAATCGTGATCGTTGTTTTAAACAATAAAACTGCGATTCTCATTTTTGCCAGAATGGTGTAGCCTGAATAACTGTACTGTCTAGAATCATATATGTATTAAATAGATATTTTTTTCTTTTTTCTTCCATTAGACATGGTTACTCAGGGTTTGGAGTTGTCAAAAAAGCCACATGTTGTTGTTGCCACACCGGGACGACTTGCTGATCACATTCGCAGCTCTGACACAATTAACCTGAACAGAATCCAATTTCTAGTAAGACGATCATTTTGTCTGCCTTCAAGCTTTTTTTTTAATATCAAAGCAGTTTTGATGTAATTAACGTGTCTTTTGACAGATCATGGATGAAGCTGATCGTCTTCTGGAGCAGGGCTG[T/A]ACTGATTTTACTAAAGATTTAGAGGTCATTCTCAGTGCGGTGCCAGTAAAGCGGCAGACTCTTCTGTTCAGTGCCACGCTCACAGACACGCTGCAGCAGCTGCAGAGCATCGCTATGAACAGGCCCTTCTTCTGGGAGCATAAATCAGAGTAAGACACTGTCAGACGTGTGTTAGGCGAATGAAGATATGTAAAGTGCTGAATTAATTTTTTTTTATGAAATTTGGCTTCTGCTGGTTTCAAATCAGGAACCAGAAATGTTAGTGGCTGGTGTTAGGCTTCTGGCAGTGTAAAATGTTCTTTTTCAAATAATTGCTTAACTTTTTATTACAGAAATTGACCTTAAATTATCATGATATTACTAGTTAAATTGAAACACTTTGCAATAAATTATCATTAGTGCATTTTAGTTAGTTAATTAATTAAAATCAACACTCAGAAATGGCCATATCATAGGTGTGTGTTAAAGGGAATACAAATAAATACAACTGAATTCTTTTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa24887

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000007204	Essential Splice Site	310	468	9	13

Genomic Location (Zv9):

Chromosome 11 (position 6956803)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	6864297
GRCz11	11	6874136

KASP Assay ID:

554-7791.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CCTTTCTCTAATTTGGTTCTCTTTTCTGTGCTTGTTCTGTTCTTAACTGA[A/G]GGGGTTTGGATATTCCCACAGTTCAAGTTGTTATTAATCACAACACACCC

Long Flanking Sequence:

TGGTAATTTTCAAAAACCCATAATAGGGGCTCTTTAATAAATGTTCATTCTCAGTTCATGTTAGTAAATCTATAAATTAGCATTAACTAAAGCAGCCTTATTGTAAAGTGTAAAAATCATTTAAATAGTATCTAAAATGACATTGTTATGCAGTATTGTTGTTCTAATGTTCCAGGAGCTGTCAGATACTCACTATGATGCTGCGGGAATTCAATTTCCCAACCATCTCTCTGCACTCAATGATGAAGCAGGTAAGTGATGTAGTTAAAATTGATTCTTACTCCGTCCCTAATGTCTGTACTAATGCTTTTTCTCTTTTACAGAGACAGCGTTTTGCCAACCTTGCAAAATTCAAGTCTAACGTCTTCAAAATTCTCATAGCCACAGATGTTGCTGCCAGGTACAGAAAACACTTCTCAACACAACTCGCCAGTGTCTGTAATCTCTTTGCCTTTCTCTAATTTGGTTCTCTTTTCTGTGCTTGTTCTGTTCTTAACTGA[A/G]GGGGTTTGGATATTCCCACAGTTCAAGTTGTTATTAATCACAACACACCCGGTTTGCCAAAAATCTACATCCACAGAGTAGGACGAACCGCTCGAGCTGGTGAGTTTGCATATGTTAACAACATAATTGAAAGCCTGTTTGAATGAAGCAATTGTTTTTATAAGTCGTAAATCAGCCGTTATTGTTTTTCTCTAGAATAAATTATTAACAGCAGGTATTGGCTTCTACTAATAATATATACATTTAATTTGTCTAAAATCAAAATGTTCGATGTTTAATTTGCTCGTTCATATTGTTATTCTGATGCTGTGTTCACGCCAGACTCGGCACTCGTGATTAAATCCTGCTATTCTTGCGTAAATGAACATTTAGAGTTTACCCATTTCATTCATGCGTCTAATTTGCTTCATTCGTGTGTCAAATTCACTTCACAATAGAAGTGGATTCGCTTTATGGGTGGGGCTTCTGTCTACCCAGTGATACTAGCTACGTTGCTAAAT

Associated Phenotype:

Not determined