ZMP
mll2
Ensembl ID:
ZFIN ID:
Human Orthologue:
MLL2
Human Description:
myeloid/lymphoid or mixed-lineage leukemia 2 [Source:HGNC Symbol;Acc:7133]
Mouse Orthologue:
Mll2
Mouse Description:
myeloid/lymphoid or mixed-lineage leukemia 2 Gene [Source:MGI Symbol;Acc:MGI:2682319]
Alleles
There are 22 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa14115 | Essential Splice Site | Available for shipment | Available now |
| sa32447 | Nonsense | Available for shipment | Available now |
| sa16818 | Nonsense | Available for shipment | Available now |
| sa10227 | Nonsense | Available for shipment | Available now |
| sa24354 | Nonsense | Available for shipment | Available now |
| sa24355 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa14115
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000053863 | Essential Splice Site | 213 | 4967 | 5 | 53 |
| ENSDART00000131379 | None | None | 461 | None | 6 |
| ENSDART00000134785 | None | None | 235 | None | 3 |
| ENSDART00000137103 | Essential Splice Site | 213 | 368 | 6 | 9 |
| ENSDART00000141458 | None | None | 308 | None | 7 |
Genomic Location (Zv9):
Chromosome 23 (position 28008203)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 27841025 |
| GRCz11 | 23 | 27767566 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGCTGGCGCTCCTYTGTCCAGAGCACATAGACAAGGCTGAGGAGATTGG[T/A]ACGGAATTGCAGAAGAAGAGATGCGATATGATCAGTAAATAAHGATCAGG
Long Flanking Sequence:
AGCAATGGCTATGGTTTGTTTATGTTTGAAAGATATATACGAACTCTCAACCTTTTTCCGTAAACATGTTTTCTTCTATGTAGTTTTTATAACTCCAAATCCTTTTTTCTGAATCAGGGAGCTGCTGGGTTCACCACTGGTGTGCCGTGTGGTCAGAGGGAGTGGAACAGACTGAGGGTGAGGTGCTGATAAACGTGGATAAGGCAGTCGTCTCAGGGATACAGCGGGTAGGCACAGAGCTTCCTTTATCAAAGCATTAAGCCTCCATAAATATTGCTTTATGACAGGCAAATTAACTTTTCCATCTTTTACCTGGCTTTTGTATCTCTGCTTCAGCCATGTGATTATTGTAAACGGATGGGTGCTACTATCCGCTGCCGGGCCGAAGGCTGCTCACGGTTTTACCACTTCCCCTGCTCGGCTGCAAGTGGATCCTTCCAGTCCATGAAGCAGCTGGCGCTCCTCTGTCCAGAGCACATAGACAAGGCTGAGGAGATTGG[T/A]ACGGAATTGCAGAAGAAGAGATGCGATATGATCAGTAAATAATGATCAGGATTGCTGAGATGAGTCTGTGTTTGTTTTGCAGCCGGAGAGGAGGCACGGTGTGCAGTGTGTGACTCGGTTGGAGACCTGTCGGGTTTGCTGTACTGTACTGGATGTGGGCAGCACTATCACGATGCCTGTCTGGAGATTAGTGCTACACCACTTCAGCGGTCAGGATGGCAGTGTCCTGAGTGCAAGGTGTGCCAGACCTGCAGGTATGTTGGAATAGATCTAGCATTTTTACGTTATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATATAAAATGTTTTATAGAGATTGTGGTAAAAGTGCATTTTCTTTAATAACATCCAGGCAACCAGGGGAGGATTCAAAGATGCTGGTTTGCGATGCTTGTGACAAGGGCTACCACACCTTCTGT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa32447
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000053863 | Nonsense | 883 | 4967 | 15 | 53 |
| ENSDART00000131379 | None | None | 461 | None | 6 |
| ENSDART00000134785 | None | None | 235 | None | 3 |
| ENSDART00000137103 | None | None | 368 | None | 9 |
| ENSDART00000141458 | None | None | 308 | None | 7 |
Genomic Location (Zv9):
Chromosome 23 (position 28013182)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 27846004 |
| GRCz11 | 23 | 27772545 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGTCTTGAGTGCATTGTGTGTGAGGTGTGTGGGAAGGCTTCAGATCCTT[C/A]ACGGTTACTGCTTTGTGATGACTGTGATGTCAGCTATCACACTTACTGCT
Long Flanking Sequence:
CATGACTGCAGACACTGGAATTAGCAAAGAGGAAGATGAGGAGGAAGATGACACCATGCAAAATACTGTGGTACTTTTCTCCAACACTGATAAGTTTGTCCTGCAGCAGGTATGAATCTCATTGCTCTTTACCTTTGCTTTCATATAAAGTACAAGATCACAATAATCTGATTCATCTTGTGTGTGTTTGTGTGTGTGTGTGTGTGTGTGTGCGTGCAACAGGACATGTGTGTAGTTTGTGGTAGTTTTGGACAGGGTGTGGAGGGCCAGCTCCTAGCATGTGCTCAGTGTGCACAGTGTTATCATCCATACTGTGTGAACAGCAAGGTAAGTTATTTATTTATTTTTACATTTATTCTGCACAAGAACCCCGTTTTACACTGTCTCTCGTTATCTGTTTGTTTGATTATCTCTAAAGATCACCAAGATGATGTTGAGAAAAGGCTGGCGTTGTCTTGAGTGCATTGTGTGTGAGGTGTGTGGGAAGGCTTCAGATCCTT[C/A]ACGGTTACTGCTTTGTGATGACTGTGATGTCAGCTATCACACTTACTGCTTGGACCCACCCTTACAGACGGTCCCCAAGGGAGGCTGGAAGTGCAAATGGTTTGTCATTGCTGCTATACCTATGCATATGTTTTTTTTTACATATGTGTGTCAGTTGGGATCCCAAAGAGAAAATGTGGTAATTGAGCTATTGATCTACCACCCCATCAGGTGTGTGTGCTGTATGCAGTGTGGTGCCAGCTCCCCTGGGTTTCACTGTGAGTGGCAAAACAACTACAATCACTGCGGCCCCTGCGCCAGCCTGGTAACATGTCCTGTGTGTCATGAGAACTTCATGGAGGAGGAGCTGCTTCTGCAGTGTCAGCACTGTGACAGGTCAGTAACTGCTATATTTTATTGAACTTGTTACTAAAACAATAGTGAGAGAACAAAATTAAGTTTTCTCCTAAAATAATGAGCAGCACGTATGATAAGCGTGATGCCAAAGAACTAGTGATGAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16818
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000053863 | Nonsense | 2316 | 4967 | 33 | 53 |
| ENSDART00000131379 | None | None | 461 | None | 6 |
| ENSDART00000134785 | None | None | 235 | None | 3 |
| ENSDART00000137103 | None | None | 368 | None | 9 |
| ENSDART00000141458 | None | None | 308 | None | 7 |
Genomic Location (Zv9):
Chromosome 23 (position 28021800)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 27854622 |
| GRCz11 | 23 | 27781163 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTGATCCCAGACTTGGGTTACAGCAGGGTGGCATGGACCTATTGATGCAA[C/T]AACAAAGCAATGCACCTCCTCCTCAGTCTCAACTACAGCCACAGCAGGTG
Long Flanking Sequence:
AAACATTTTGTAACCTACTTTTTTTTTTTTAAAGGCAAGCTGGGCCTGTTTCTCAGGGGATGTATCCACGTCCACAATTTCCTGCACAGTGGCAAAACCAAGGAGCTCCACGGAGATTTCCACAACCATCTATGATTGAAGCCGTTCCCAGGCAGCACCTTACTACTCCCATCAACAATCCTCTCAACATGCAATCCATGCAGAATATGCCCAATCCTTTGACCACAGTTCCAGGCACTGGAACAGAGGCAGTACAAAGCCATGTTTCAGGAGCTCCACCTCAGTTTATTGAGTTGAGGCATAATTCCCAAAGGATGCCACCGGGTCCTCAGTTTATGCAAAGGGCACCGATACCCAGAGCGCGCATGTTTCTTCCACAGCAGGAAATGAATGCTGCTTTTGCTCAGCAGAATTTAACCTCATCTCTTGATGCTTCGGCAGTAGGAATGCGTGATCCCAGACTTGGGTTACAGCAGGGTGGCATGGACCTATTGATGCAA[C/T]AACAAAGCAATGCACCTCCTCCTCAGTCTCAACTACAGCCACAGCAGGTGCCAACTACTACTCCCAAAACACAAATTTCTCACACTACTCAACAACTTCCTCAAACTACTTCAATAGGCAGTCAGCAGACTGGTGTGAATCCAGTTGACCTACCTGAGTCTGACCTAGTGGATGCCTTTGCTCCCAAAGGACTGAGTGATCCGGTGGCAGAAACTGGAGTGGAGGATGATGATCTTGGTCTTGACCTTGATCCTGATAAAGGGGATGATGATTTGGGAAACCTTGACAATCTTGAGGCCAATGATCCTCATTTGGACGATCTGCTCAACAGCGATGAATTTGATTTGCTTGCATACACTGACCCTGAGCTTGATCAGGGTGATCCCAAAGATGTTTTCTCTGACCAGTTGCGACTTGTGGAAGCAGAGGTGGAAGGTCCAGTGTCTTCTGCTAATGTTGAAGTCAAGGTTGAAGTGAAACCAAAAGTTGAAATGGCTTCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa10227
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000053863 | Nonsense | 2746 | 4967 | 33 | 53 |
| ENSDART00000131379 | Nonsense | 129 | 461 | 1 | 6 |
| ENSDART00000134785 | None | None | 235 | None | 3 |
| ENSDART00000137103 | None | None | 368 | None | 9 |
| ENSDART00000141458 | None | None | 308 | None | 7 |
Genomic Location (Zv9):
Chromosome 23 (position 28023090)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 27855912 |
| GRCz11 | 23 | 27782453 |
KASP Assay ID:
2261-7892.1 (used for ordering genotyping assays)
KASP Sequence:
GCCAGCCTGGCAGACTTCATCCTGGTCTTGCTCCACAGCAGCAGWCAACA[C/T]AACCTCCACATATTGGTAAACAGCAGAACTTTTTCCCAGATAAAGGTTTK
Long Flanking Sequence:
AAGCTGATACACTGTCTTTTCCAGCAACTGCACCTCATCCAGACCTGGGCAGTGACCCACTTGGATTGCCAGATTCTGGCCACCACTCTACAGCAGATGATCTTGACAAAGTTGAAAGCTCACTGGAAGCGAGTGAACTGCCTTTGCTCATTCAAGATCTTTTAGAGCATGAAAAAAAGGAGCTCCAGAAACAGCAGCAGTTAAGTGCTCTACAAGGCGGGATTGGAAGTCAAATTCACAGCATTCAGAATCAACAACAGCCCCCTCAGACTACAAATCAAATTATGATGCCACAGCACCATCATCCATCCCAGGGCATAGTGCCTCAAGCAGGTATGGTGCCCAGGCCACCTCACATGTTCCCACAGCAGCAGCAAAGGCTGATTAGTGCTGCAATGCCTTCACCTCCCCATGCGGCAATGGGACAGCAGCCAGGCATTTTAAGGGGTGGCCAGCCTGGCAGACTTCATCCTGGTCTTGCTCCACAGCAGCAGACAACA[C/T]AACCTCCACATATTGGTAAACAGCAGAACTTTTTCCCAGATAAAGGTTTGTTTGAGTTTCATAAACTTGATGTGTATTACACATGTATATGATATACAAAAAATTACTTATTCTTGTAAATATATATTTTTTTCAGATCTGGATAAATTCATGACTGATGACATAATAGATCCTATTGCGAAGGCTAAAATGATTGCTTTGAAAGGCATTAATAGGGTGTTGGCTCAAGATCCAATGGGTGTACCACCTGGCATGAATAGGTACTGTTTTTGTTTGTTTGTTATGAAAGACGTTCTGTCGGAATTCCAATATCATGAGCTCATATGTAAAGCAAAAATGTAAAAAGTCTATTTCAGCCTTGTTTGAGATGTAATTTTATTTAACTATAGGCAACAAGTATCTCTACTGGCTCAGAGGTTAACCTCTGCCCCTGGGAATGAGGATTCCCAACCTCCGCCTGCCCCTGGCTCTTCCAAGGTCAGTTAAGTAGCATTCTTTAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa24354
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000053863 | Nonsense | 3706 | 4967 | 38 | 53 |
| ENSDART00000131379 | None | None | 461 | None | 6 |
| ENSDART00000134785 | None | None | 235 | None | 3 |
| ENSDART00000137103 | None | None | 368 | None | 9 |
| ENSDART00000141458 | None | None | 308 | None | 7 |
Genomic Location (Zv9):
Chromosome 23 (position 28026581)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 27859403 |
| GRCz11 | 23 | 27785944 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATCACCTTCAAGGCCAGAAGGTATTGTAGGAAAGAGTAGCCCCTTTAGC[C/T]AGACGGGGGGTTTGATACCTTCACCTCTGAGATCTCCAACTGCCAAGACT
Long Flanking Sequence:
AGTTTCATCAGGGTGTAATAGGCGCAATGCAACAGCCTTCTCAAGGACCTTTGCCTCAGTACATCAATAGTGCCCAGCAGCAGCAAATGATACAGCAGCAACAAGTGCATCAGCATCAAATGATGAGGGGTCAAGTGCCTAGACCAATAATGGGTCAGGTTCGCAACACAGCACCTGGACATCTGGCTAGACCAATGTCTCCTCGCCAATTACTGGGGCAGGGATCACCTGGAAGTCCACTTTCTAATCAACAAAGACTCGTGAGGATGTCTCAGACTCCTCCAGGCACTCAGCATCTTCAACAACAGACACATGGTACAACAGCACTGAGCCCCTTTCAAGCATCTCCCTCGCATGCTGGTTCTCCTGCAGGGTCTTCTGTTCCAGAAGCTGGTAGTCCATCTTTAAATAAACCTGAACCAGGTAACATGGCCCTCTCCAGTAACTTGTCATCACCTTCAAGGCCAGAAGGTATTGTAGGAAAGAGTAGCCCCTTTAGC[C/T]AGACGGGGGGTTTGATACCTTCACCTCTGAGATCTCCAACTGCCAAGACTCAGAGCCCTAATACTGAAGCTCTCTCAGCTCCTTTCCCACTTAATGGGCCGTCTTCTCAGGTAGCACAGAACCAAGCACCAAATTCTGGTCAAATATCTGGGGGTCATACATCTCAACCAACTCAAATGCCCAGTGAAATGTGCAAGATGACATTGCAAAACATTAAACAAGAGCCACGAGAAGTCCAGTGCGATACAGGAAATATTGTTGAGACTCATTCTGATGGCATAAAGAGAGAAATTTCTGGAGAATCTGTCAGTGGCTCTGGTATTGTGAACTCTGCTGTGGGCTCTAGAAATCAAGCAGGAGATATTGGATCGCAAATTCAAAGGACAGAGACTGGCCAACAACTACTACAGAAACTCCTTCGAACCAAAAACTTGCAGGTTGCAGCTCAGAGGCCCTCAGATGGTATTCATAATGAGATAAATGGACACATTAATAACAAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa24355
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000053863 | Nonsense | 4406 | 4967 | 47 | 53 |
| ENSDART00000131379 | None | None | 461 | None | 6 |
| ENSDART00000134785 | None | None | 235 | None | 3 |
| ENSDART00000137103 | None | None | 368 | None | 9 |
| ENSDART00000141458 | None | None | 308 | None | 7 |
Genomic Location (Zv9):
Chromosome 23 (position 28029669)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 27862491 |
| GRCz11 | 23 | 27789032 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCTAAAATCCATCAAACACCGTAGCAGGCCTCTTTCTGATGAAGAACAA[C/T]GACCTAAGGTCAAAAAATGGAAAGGTTTGCGCTGGAAACGACTCCAGATA
Long Flanking Sequence:
GTACATTACATTTATTTGTGCTTTTTACCTTTCTTTTGCAGGAATCCCAAGAGCAAGAAGATAAACCTGCCCAACACTGTTACATGACAAATGTTTCAGATCTGGATGTGCGCCACCTGCCTGTTATTCCTGTCGAAGTATCTCCACCTCCTTCACCATCTCCACCTCCACCCCCATCATCTACTGTAGCTGAGCCCGAAAACACCACTCAGCCTGAGCCCAAACCTGAATCTGAAGCAACTGTTCAGACTACATCATCCCCTTCTGCAAGTCCAAGTGCTCCTGTCAAAACCGAAATTTTGGTCAAACAGGAATCTCACTGCTCCCCCGTTACAGTAGAGCCTGAATCTCATGAGCCTGCGGTCCTACCTATAGCTGTTCCACCACCACAAGAACAACCTTCTGCTCCAGCAAGTTCTCCTCCTCTAGACTCCCCTACTATAGAGATATCCCTAAAATCCATCAAACACCGTAGCAGGCCTCTTTCTGATGAAGAACAA[C/T]GACCTAAGGTCAAAAAATGGAAAGGTTTGCGCTGGAAACGACTCCAGATAGTCATAACTATTCGCAAAGGTGGCTCTAAAAAAGAGAGCAGTCGTGAAGTTTCAGAGCTCATGGAGCGCCTCCGCATTACACTGAAACCAGATAAGTTGCCTAGAGATAAGCGCAAGTGCTGTTTCTGCCATGAGGAGGGAGATGGTGCAACAGATGGTCCTGCACGCCTGCTTAATATTGATGTTGATTTGTGGGTGCATCTTAACTGTGCTCTGTGGTCAACAGAGGTGTACGAAACCCAGGGTGGTGCACTTATTAATGTGGAGGTTGCCCTTCGGCGTGGATTACGCACCCGTTGTGCCTACTGTCAAAAAACGGGTGCTACTAACAGCTGCAACCGTTTACGCTGCCCGAATGTATATCATTTTGCATGTGCCATTCGGGCACGTTGCATGTTTTTCAAAGACAAAACTATGCTCTGCACTCAGCACAAGCTTAAAGGTCCCAGC
Associated Phenotype:
Not determined