Busch Lab

ZMP

krt8

Ensembl ID:
ENSDARG00000058358
ZFIN ID:
ZDB-GENE-030411-5
Description:
Keratin, type II cytoskeletal 8 [Source:UniProtKB/Swiss-Prot;Acc:Q6NWF6]
Human Orthologues:
KRT8, KRT8P11
Human Descriptions:
keratin 8 [Source:HGNC Symbol;Acc:6446]
keratin 8 pseudogene 11 [Source:HGNC Symbol;Acc:31058]
Mouse Orthologue:
Krt8
Mouse Description:
keratin 8 Gene [Source:MGI Symbol;Acc:MGI:96705]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa1629 Nonsense Available for shipment Available now
sa37629 Nonsense Mutation detected in F1 DNA Not yet available
sa43921 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa31084 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa1629
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081215 Nonsense 6 520 1 9

The following transcripts of ENSDARG00000058358 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 10360380)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 10319182
GRCz11 23 10254152
KASP Assay ID:
554-1570.1 (used for ordering genotyping assays)
KASP Sequence:
TCATTCTCTACAAGACAGAAAACACACAAGGCAGGATGTCCACCTACAGC[A/T]AGAAAACCAGCTACACCGTCAAGTCTTCTTCCTCTGGATCTATCCCACGC
Long Flanking Sequence:
GCCTTGCATTGAAGGATTTCAATACTAATGTTTAATTTTACTGACATACAACGTTTTAAAATGTTGGTATTTTGGCTTTTATTGAAAGTGTGATTCATTTTGTACAAAATAAAACAAGGTATATTAACTTGAACAAACTGAGGGAGGGTCACTAGTTTTTCAAGCACTTAATTATCCCAGAAAATGTCTGTTTCTGGTCATATTGAATTACAAAAAAGATCCATGTACTGGTTAGACTAGGAATGCAGGACAATGTTGGATTGAATTTCAGCCACACCCACCTTCTACACCTAAACACCGACCAATCAGACCCCTCCTTTGGCTCCACCCACTCCGTGTCCAGCGCATAAAGAGCAAGACAGAGTCAGCCGTTCTCTCTATCTGCTCGAGTTTCTCCAGCACAGCAGACAAGGCTCATATCTGCTGCTCTCGCTCCCCCTTTGCTCCAGGTCATTCTCTACAAGACAGAAAACACACAAGGCAGGATGTCCACCTACAGC[A/T]AGAAAACCAGCTACACCGTCAAGTCTTCTTCCTCTGGATCTATCCCACGCAACTTCAGCAGTTTGTCTTATTCCGGCCCCAGCATGAGCCGGCAGAGCTACAGTGCACGCAGCTCCTATGGAGGTGTCAATCGTGGCATGGGAGCTGGAATGGGAGGTGGTAGTGGCTTCATCTCTAGCTCTTCAGCCTACGGTCTTGGCATGGGCATGGGTACCGGAATGGGTGCAGGAGTCGTGGCACCAATTCAAGCAGTCACCGTCAACAAGAGCCTCCTGGCACCTCTGAATCTGGAGATCGACCCCAACATCCAAATTGTCCGCACCCAGGAGAAAGAGCAAATCAAGACCCTCAACAACCGCTTCGCTTCCTTCATTGACAAGGTAGGTTTGACATTTCTTTTTTTGGAGTTTTTTGGAGCAGAAAAGTGGAAAAACTGACTGCGTTCTTGCTTAAAAAGTCTGTAAAAGTTAGTCTAGAGTGGAACAGAAACTATATATTGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37629
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081215 Nonsense 109 520 1 9

The following transcripts of ENSDARG00000058358 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 10360071)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 10318873
GRCz11 23 10253843
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAACAAGAGCCTCCTGGCACCTCTGAATCTGGAGATCGACCCCAACATC[C/T]AAATTGTCCGCACCCAGGAGAAAGAGCAAATCAAGACCCTCAACAACCGC
Long Flanking Sequence:
ACCCCTCCTTTGGCTCCACCCACTCCGTGTCCAGCGCATAAAGAGCAAGACAGAGTCAGCCGTTCTCTCTATCTGCTCGAGTTTCTCCAGCACAGCAGACAAGGCTCATATCTGCTGCTCTCGCTCCCCCTTTGCTCCAGGTCATTCTCTACAAGACAGAAAACACACAAGGCAGGATGTCCACCTACAGCAAGAAAACCAGCTACACCGTCAAGTCTTCTTCCTCTGGATCTATCCCACGCAACTTCAGCAGTTTGTCTTATTCCGGCCCCAGCATGAGCCGGCAGAGCTACAGTGCACGCAGCTCCTATGGAGGTGTCAATCGTGGCATGGGAGCTGGAATGGGAGGTGGTAGTGGCTTCATCTCTAGCTCTTCAGCCTACGGTCTTGGCATGGGCATGGGTACCGGAATGGGTGCAGGAGTCGTGGCACCAATTCAAGCAGTCACCGTCAACAAGAGCCTCCTGGCACCTCTGAATCTGGAGATCGACCCCAACATC[C/T]AAATTGTCCGCACCCAGGAGAAAGAGCAAATCAAGACCCTCAACAACCGCTTCGCTTCCTTCATTGACAAGGTAGGTTTGACATTTCTTTTTTTGGAGTTTTTTGGAGCAGAAAAGTGGAAAAACTGACTGCGTTCTTGCTTAAAAAGTCTGTAAAAGTTAGTCTAGAGTGGAACAGAAACTATATATTGGGTTTAAACACTTGAGAAAGTAAGGGCGAGTAGAAAAGGGTGTGTGCATGGTCAGAGTGTGATGGCTTTTCATTTAAATGAGATGCCTTGAGGCGCTTCTGAAACCCTTCTGAAGAGTCCACACCCAAAAAAGGACGCCCTGCAGGACCTGAAACCTGTTTTATACATCTTATCATTACAAGCCATGAATTACATTTCCAGAATCCAAACAAAATGTACAATCAACTAAATGTCACATTCTTTTGTAGTTAATATTTAATTTGAAGAACCAGGGTCATGTGCTGGATAGTACTAGATAGATTACGTAACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43921
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081215 Essential Splice Site 132 520 1 9

The following transcripts of ENSDARG00000058358 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 10359999)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 10318801
GRCz11 23 10253771
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGAGCAAATCAAGACCCTCAACAACCGCTTCGCTTCCTTCATTGACAAG[G/A]TAGGTTTGACATTTCTTTTTTTGGAGTTTTTTGGAGCAGAAAAGTGGAAA
Long Flanking Sequence:
CTGCTCGAGTTTCTCCAGCACAGCAGACAAGGCTCATATCTGCTGCTCTCGCTCCCCCTTTGCTCCAGGTCATTCTCTACAAGACAGAAAACACACAAGGCAGGATGTCCACCTACAGCAAGAAAACCAGCTACACCGTCAAGTCTTCTTCCTCTGGATCTATCCCACGCAACTTCAGCAGTTTGTCTTATTCCGGCCCCAGCATGAGCCGGCAGAGCTACAGTGCACGCAGCTCCTATGGAGGTGTCAATCGTGGCATGGGAGCTGGAATGGGAGGTGGTAGTGGCTTCATCTCTAGCTCTTCAGCCTACGGTCTTGGCATGGGCATGGGTACCGGAATGGGTGCAGGAGTCGTGGCACCAATTCAAGCAGTCACCGTCAACAAGAGCCTCCTGGCACCTCTGAATCTGGAGATCGACCCCAACATCCAAATTGTCCGCACCCAGGAGAAAGAGCAAATCAAGACCCTCAACAACCGCTTCGCTTCCTTCATTGACAAG[G/A]TAGGTTTGACATTTCTTTTTTTGGAGTTTTTTGGAGCAGAAAAGTGGAAAAACTGACTGCGTTCTTGCTTAAAAAGTCTGTAAAAGTTAGTCTAGAGTGGAACAGAAACTATATATTGGGTTTAAACACTTGAGAAAGTAAGGGCGAGTAGAAAAGGGTGTGTGCATGGTCAGAGTGTGATGGCTTTTCATTTAAATGAGATGCCTTGAGGCGCTTCTGAAACCCTTCTGAAGAGTCCACACCCAAAAAAGGACGCCCTGCAGGACCTGAAACCTGTTTTATACATCTTATCATTACAAGCCATGAATTACATTTCCAGAATCCAAACAAAATGTACAATCAACTAAATGTCACATTCTTTTGTAGTTAATATTTAATTTGAAGAACCAGGGTCATGTGCTGGATAGTACTAGATAGATTACGTAACAGCAAGGCAACAAGAAGAGGAAATATTCTGTCACACATTTAGCTCTTAAGTATTTATGTCCTTCCTCTTAATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31084
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081215 Essential Splice Site 439 520 8 9

The following transcripts of ENSDARG00000058358 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 10356728)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 10315530
GRCz11 23 10250500
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAACAGACTGGCAACTGGAATCAAGGCCATCAATATCTCAAAACAGAGCA[G/A]TAAGTTTGACTCCTTTCAAGACTCTTCCTTCACATAATAATTCAATGCAA
Long Flanking Sequence:
ATGGCACGCCAGATTAGAGAATATCAGGACCTGATGAATGTAAAATTAGCCCTAGACATCGAGATCGCCACCTACAGGAAGCTCCTGGAAGGAGAAGAGGACAGGTGGGTTCAACAAATGCACACCTGCTGTATAGAATCAATAATCCTCAAGTAGCTGTGGCTCACAGCTAATTTATAACAGCTAAGGGGAGTTGTTGTACATGACACAGAGTTCTATACATTTACTGTAAATCATGTCTTCAGGGCTTATTGCTTTTACACAATGGTAATTTCATTAAAATAAATTTAAAGCAAATGTAGTTTCCTTGGCTCAGTACCAGGCAACAGTCACAGGTTTATGTTTGTATTTTACCACAGCTTCAAACATAGCTCAACCAATCAGAATTATAATTGCTTCATAATTTGAGATTTCTGTACAAGATAGTCATTGCTTTTCCCACTCTTTTTTTAACAGACTGGCAACTGGAATCAAGGCCATCAATATCTCAAAACAGAGCA[G/A]TAAGTTTGACTCCTTTCAAGACTCTTCCTTCACATAATAATTCAATGCAATGAACTGTCCTCTACAGAATCTACATCTTACATCTTTCTGTCCCGATAGCGAGCTATGGTGGATATCCTATGGAAAGTGCCGGCAGCAGCTACAGCACCTACTCTAGCGGTTACTCCAGCGGTTTATCTGGAGGATATGGTGGCGGATACAGCGGCGGATACAGCGGTGGCTACAGCTCAGGCAGCGGCTACAGCGACACCGTCTCTCAGACCAAGAAGAGCGTCGTGATCAAGATGATCGAGACCAAGGATGGCAGAGTTGTGTCCGAGTCCTCTGAAGTAGTCCAAGATTGAGCAAGTCCTTCCCCCAGTTGTGTCCACTAAACGTCACGCCTCTTCATGACCTTCCCTCTCAACCATTATGGCTGCGGCCCAAAGCTCTAGACAGAAAAGCAGCCATAAAGCAGGTTGAAAGCCACTCACACTGACCAAAGAATTCCAGAGGGACCA
Associated Phenotype:
Not determined