ZMP
krt5
Ensembl ID:
ZFIN ID:
Description:
keratin 5 [Source:RefSeq peptide;Acc:NP_571231]
Human Orthologues:
KRT8, KRT8P11
Human Descriptions:
keratin 8 [Source:HGNC Symbol;Acc:6446]
keratin 8 pseudogene 11 [Source:HGNC Symbol;Acc:31058]
keratin 8 pseudogene 11 [Source:HGNC Symbol;Acc:31058]
Mouse Orthologue:
Krt8
Mouse Description:
keratin 8 Gene [Source:MGI Symbol;Acc:MGI:96705]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa37628 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa29880 | Essential Splice Site, Missense | Mutation detected in F1 DNA | Not yet available |
| sa31083 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa43920 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa37628
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000081223 | Essential Splice Site | 264 | 561 | 3 | 10 |
| ENSDART00000081327 | Essential Splice Site | 251 | 553 | 3 | 9 |
| ENSDART00000129044 | Essential Splice Site | 264 | 566 | 3 | 9 |
| ENSDART00000144280 | None | None | 201 | None | 3 |
| ENSDART00000146185 | Essential Splice Site | 60 | 226 | 3 | 7 |
Genomic Location (Zv9):
Chromosome 23 (position 10282223)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 10240364 |
| GRCz11 | 23 | 10175334 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATCAACAAGCGTGCCGCAGTGGAAAATGAATTTGTCCTGCTGAAGAAGG[T/G]AAAACCTTCATCTGCTGTGTTGATTTTTATTTAAAATAGTTATTACTTTC
Long Flanking Sequence:
CTTGAGAGGTGTGATTGATAATTACTGTGGAAGATACATCTTGTTGATTATCAAAGATCCCTCATACCTTATTTTGCTAACTCAACAATTTATTCAAATCCTCCATCTCTTTATCTCCAACACAGGTGCGCTTCCTGGAACAGCAGAACAAAGTACTCGAGACAAAATGGAGTTTATTGCAAGAACAGACCACTACCCGATCCAACATCGATGCCATGTTCGAGGCCTACATCGCCAACCTGCGCAGACAGCTTGACGGACTTGGCAATGAGAAGATGAAGCTAGAAGGAGAGCTGAAGAACATGCAGAACTTGGTGGAGGACTTCAAGAACAAGTAAGCAGCCGTGCTAAAACATGTTTAGAGGCTATGAGCTACATTATGTGTTGGTGGTATAATTTGACAAGCATTTTGCTAAAATGGAAAACTTTTCTTTGCAGATATGAAGATGAAATCAACAAGCGTGCCGCAGTGGAAAATGAATTTGTCCTGCTGAAGAAGG[T/G]AAAACCTTCATCTGCTGTGTTGATTTTTATTTAAAATAGTTATTACTTTCACTTTAGTCAAATGAGTCCGTTACTGAGGTATGTGCATGCCTTCATAGGATGTCGATGCTGCCTACATGAACAAGGTTGAGCTTGAGGCCAAGGTTGACTCCCTTCAAGATGAAATCAACTTCCTTAGGGCCATCTTTGAGGAGGTGAGAGTTTGATGGCGCTTTTTTACCACTGACATGCAATTTCTTTTTTTGTCAGCTGTCTCTCAATGCCATATTCCTTTACCTTGCCATTTTAGGAGCTGCGTGAACTCCAGTCACAGATCAAAGACACATCAGTCGTTGTGGAAATGGACAACAGCCGCAACCTGGACATGGATGCTATTGTTGCTGAAGTCCGCGCTCAGTATGAAGACATCGCCAACCGCAGCCGTGCTGAGGCCGAGTCCTGGTACAAACAGAAGGTGAGCAAGACTTTCAAACACCAAACCAACATTGCTTTAAATGTAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa29880
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site, Missense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000081223 | Essential Splice Site | 516 | 561 | None | 10 |
| ENSDART00000081327 | Missense | 503 | 553 | 9 | 9 |
| ENSDART00000129044 | Missense | 516 | 566 | 9 | 9 |
| ENSDART00000144280 | None | None | 201 | None | 3 |
| ENSDART00000146185 | None | None | 226 | None | 7 |
Genomic Location (Zv9):
Chromosome 23 (position 10280831)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 10238972 |
| GRCz11 | 23 | 10173942 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGATACGGTGGTGGCAGTGGATTCGGTGGTGGCAGTGGATACGGTGGTG[G/A]CAGTGGTTTCGGAGGTGGCAGTGGATTTGGATATGGTGGTGGCTCAGGGA
Long Flanking Sequence:
GCCAAGCTCCGCATTAAGGATCTGGAGGACGCCCTGCAAAGAGCAAAGCAGGATATGGCGCGCCAGGTGCGTGAGTACCAGGAGCTCATGAACGTCAAACTGGCCTTGGACATTGAAATCGCCACCTACAGGAAGCTTCTGGAAGGAGAGGAATCCAGGTCAGTCACCTTGCTTCTCAAATTAAGCTATGAATATAATGTCTTGAAATCTGTTCCCTATTGACATTCATTTATATTTTACTTCATCAGAATTGCATCTGGTGGCAATACTGCAACTATCCACATCCAGGAATCAAGCAGCAGCAGTAAGTTTCTAAAAGCTATATACAAGGCTTTATCATCAATGGTGTTTTTTTTGTGTAACTGCATTTGAGTTTTATAAGACTAATGTGTTTTTCTGTTGTTTTACAGGCGGTGGCGGCGGCGGTGGATTTGGATACGGTGGTGGCAGTGGATACGGTGGTGGCAGTGGATTCGGTGGTGGCAGTGGATACGGTGGTG[G/A]CAGTGGTTTCGGAGGTGGCAGTGGATTTGGATATGGTGGTGGCTCAGGGATGTCGATTGGTGGCGGCTCTGGCATGAGCATGAGTGGCGGCGGTGGCGGTCAAATCTCAATGTCCCGTTCTTCTATTGTGTCTAGTCAGAAGCGCCGCTTCTAAACCAAACACGTCCACCCAGATCCCTCCTTCCAAAATATCAGCTACCACCTGGGCAACTCTTTTTCACTTTTTCACTCCACATTTCAATGTTTTCGTTTCTTTTTAAAGTGTTTAACGCCCCCCCCAAAATGCCATGACCTAAAAAGACAAAGTGTTAAAAACCTGCAGAATGGCTTTTTACATTCACTGTGCTGTCTTTGATTCTTGTATCTTCTTGGCATTGCTTCTCCAACAGAATAAAACTGTCCTTTAGGGGATGCTAAATGGGAAAAGAGCTAATGAGACAGACAAAGCATGGAGCTCAAGTATTATTTCAAAGTGAATAGCTTTTGTTGCTCTGTGTCAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa31083
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000081223 | Nonsense | 522 | 561 | 10 | 10 |
| ENSDART00000081327 | Nonsense | 514 | 553 | 9 | 9 |
| ENSDART00000129044 | Nonsense | 527 | 566 | 9 | 9 |
| ENSDART00000144280 | None | None | 201 | None | 3 |
| ENSDART00000146185 | None | None | 226 | None | 7 |
| ENSDART00000081223 | Nonsense | 522 | 561 | 10 | 10 |
| ENSDART00000081327 | Nonsense | 514 | 553 | 9 | 9 |
| ENSDART00000129044 | Nonsense | 527 | 566 | 9 | 9 |
| ENSDART00000144280 | None | None | 201 | None | 3 |
| ENSDART00000146185 | None | None | 226 | None | 7 |
Genomic Location (Zv9):
Chromosome 23 (position 10280797)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 10238938 |
| GRCz11 | 23 | 10173908 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTGGATACGGTGGTGGCAGTGGTTTCGGAGGTGGCAGTGGATTTGGATA[T/A]GGTGGTGGCTCAGGGATGTCGATTGGTGGCGGCTCTGGCATGAGCATGAG
Long Flanking Sequence:
TGCAAAGAGCAAAGCAGGATATGGCGCGCCAGGTGCGTGAGTACCAGGAGCTCATGAACGTCAAACTGGCCTTGGACATTGAAATCGCCACCTACAGGAAGCTTCTGGAAGGAGAGGAATCCAGGTCAGTCACCTTGCTTCTCAAATTAAGCTATGAATATAATGTCTTGAAATCTGTTCCCTATTGACATTCATTTATATTTTACTTCATCAGAATTGCATCTGGTGGCAATACTGCAACTATCCACATCCAGGAATCAAGCAGCAGCAGTAAGTTTCTAAAAGCTATATACAAGGCTTTATCATCAATGGTGTTTTTTTTGTGTAACTGCATTTGAGTTTTATAAGACTAATGTGTTTTTCTGTTGTTTTACAGGCGGTGGCGGCGGCGGTGGATTTGGATACGGTGGTGGCAGTGGATACGGTGGTGGCAGTGGATTCGGTGGTGGCAGTGGATACGGTGGTGGCAGTGGTTTCGGAGGTGGCAGTGGATTTGGATA[T/A]GGTGGTGGCTCAGGGATGTCGATTGGTGGCGGCTCTGGCATGAGCATGAGTGGCGGCGGTGGCGGTCAAATCTCAATGTCCCGTTCTTCTATTGTGTCTAGTCAGAAGCGCCGCTTCTAAACCAAACACGTCCACCCAGATCCCTCCTTCCAAAATATCAGCTACCACCTGGGCAACTCTTTTTCACTTTTTCACTCCACATTTCAATGTTTTCGTTTCTTTTTAAAGTGTTTAACGCCCCCCCCAAAATGCCATGACCTAAAAAGACAAAGTGTTAAAAACCTGCAGAATGGCTTTTTACATTCACTGTGCTGTCTTTGATTCTTGTATCTTCTTGGCATTGCTTCTCCAACAGAATAAAACTGTCCTTTAGGGGATGCTAAATGGGAAAAGAGCTAATGAGACAGACAAAGCATGGAGCTCAAGTATTATTTCAAAGTGAATAGCTTTTGTTGCTCTGTGTCACAACATGCAAGTATTAAAGTGTACACAGAATTGTG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa43920
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000081223 | Nonsense | 522 | 561 | 10 | 10 |
| ENSDART00000081327 | Nonsense | 514 | 553 | 9 | 9 |
| ENSDART00000129044 | Nonsense | 527 | 566 | 9 | 9 |
| ENSDART00000144280 | None | None | 201 | None | 3 |
| ENSDART00000146185 | None | None | 226 | None | 7 |
| ENSDART00000081223 | Nonsense | 522 | 561 | 10 | 10 |
| ENSDART00000081327 | Nonsense | 514 | 553 | 9 | 9 |
| ENSDART00000129044 | Nonsense | 527 | 566 | 9 | 9 |
| ENSDART00000144280 | None | None | 201 | None | 3 |
| ENSDART00000146185 | None | None | 226 | None | 7 |
Genomic Location (Zv9):
Chromosome 23 (position 10280797)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 23 | 10238938 |
| GRCz11 | 23 | 10173908 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTGGATACGGTGGTGGCAGTGGTTTCGGAGGTGGCAGTGGATTTGGATA[T/A]GGTGGTGGCTCAGGGATGTCGATTGGTGGCGGCTCTGGCATGAGCATGAG
Long Flanking Sequence:
TGCAAAGAGCAAAGCAGGATATGGCGCGCCAGGTGCGTGAGTACCAGGAGCTCATGAACGTCAAACTGGCCTTGGACATTGAAATCGCCACCTACAGGAAGCTTCTGGAAGGAGAGGAATCCAGGTCAGTCACCTTGCTTCTCAAATTAAGCTATGAATATAATGTCTTGAAATCTGTTCCCTATTGACATTCATTTATATTTTACTTCATCAGAATTGCATCTGGTGGCAATACTGCAACTATCCACATCCAGGAATCAAGCAGCAGCAGTAAGTTTCTAAAAGCTATATACAAGGCTTTATCATCAATGGTGTTTTTTTTGTGTAACTGCATTTGAGTTTTATAAGACTAATGTGTTTTTCTGTTGTTTTACAGGCGGTGGCGGCGGCGGTGGATTTGGATACGGTGGTGGCAGTGGATACGGTGGTGGCAGTGGATTCGGTGGTGGCAGTGGATACGGTGGTGGCAGTGGTTTCGGAGGTGGCAGTGGATTTGGATA[T/A]GGTGGTGGCTCAGGGATGTCGATTGGTGGCGGCTCTGGCATGAGCATGAGTGGCGGCGGTGGCGGTCAAATCTCAATGTCCCGTTCTTCTATTGTGTCTAGTCAGAAGCGCCGCTTCTAAACCAAACACGTCCACCCAGATCCCTCCTTCCAAAATATCAGCTACCACCTGGGCAACTCTTTTTCACTTTTTCACTCCACATTTCAATGTTTTCGTTTCTTTTTAAAGTGTTTAACGCCCCCCCCAAAATGCCATGACCTAAAAAGACAAAGTGTTAAAAACCTGCAGAATGGCTTTTTACATTCACTGTGCTGTCTTTGATTCTTGTATCTTCTTGGCATTGCTTCTCCAACAGAATAAAACTGTCCTTTAGGGGATGCTAAATGGGAAAAGAGCTAATGAGACAGACAAAGCATGGAGCTCAAGTATTATTTCAAAGTGAATAGCTTTTGTTGCTCTGTGTCACAACATGCAAGTATTAAAGTGTACACAGAATTGTG
Associated Phenotype:
Not determined