ZMP
si:dkeyp-34c12.2
Ensembl ID:
ZFIN ID:
Description:
tumor protein p53 binding protein, 2 [Source:RefSeq peptide;Acc:NP_001038618]
Human Orthologue:
TP53BP2
Human Description:
tumor protein p53 binding protein, 2 [Source:HGNC Symbol;Acc:12000]
Mouse Orthologue:
Trp53bp2
Mouse Description:
transformation related protein 53 binding protein 2 Gene [Source:MGI Symbol;Acc:MGI:2138319]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa24196 | Nonsense | Available for shipment | Available now |
| sa43870 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa3156 | Nonsense | F2 line generated | Not yet available |
Mutation Details
Allele Name:
sa24196
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077117 | Nonsense | 39 | 1101 | 1 | 19 |
| ENSDART00000129476 | Nonsense | 28 | 996 | 2 | 16 |
| ENSDART00000136032 | Nonsense | 25 | 1060 | 1 | 17 |
Genomic Location (Zv9):
Chromosome 22 (position 31375129)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 22 | 28869238 |
| GRCz11 | 22 | 28818365 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACAGTGACAAGCACTTCACAGAGCTACCGATCACACCGGAGACTCTGTG[T/A]CGAGATGTGCTGGACATGTGTAAAGAGCCGGGAGAAGTGGACTGCTATCT
Long Flanking Sequence:
TAAAAATGTTGCCTAAAATTATTTTAAATTGAGATATTATTATTACTTATCTAGGGCTGCACGATATTGGAAAATGCTGACATTGCGATATTTTGTACTGCTGCGATATATATTACGAAATTAATATATAATTCTAGCAGATGAATCAATAACTATATTTGAAAAGATGTCGTTCATTTAGATAGATTGGGGGTGGTCAAATCTTCTTCTATGCAGTGCGTTTGCATAAATCATAATAGGTTACAAGCATATATACGTAAATAGGACGGAGCAAATATAAGTTAAATAAACAATGCGTTATAGTTTTCTGGAAAGTCTAACAGTATTCAGGTACAGAACTTGAACAATCAACATGTTCTTCTGTAGAGTATCTTCCTGTCTCCTTTGATAACATACCATGTTGTCTCTCTTTTTTCCTTGCCCCAGATGTTCCTAACGGTGTACCTGAGCAACAGTGACAAGCACTTCACAGAGCTACCGATCACACCGGAGACTCTGTG[T/A]CGAGATGTGCTGGACATGTGTAAAGAGCCGGGAGAAGTGGACTGCTATCTGGCTGAGATGTGGAGAGGATCTGGTAGGTGCTGCTGACACACAGGCGGAGATGTGTAGATTACTTACAAATTGTAATCAGTTTATTACAAAGTTTGTAGTCCTAATTGTAGTTTTTCAGATTACAGATATTTATAGTGATGTAATCTGACTACATTTGGATTACATTAGATTACTTTTGTGCTGACACCTATTTCATATACAGAGGTGAAAATAGTTGTTTAATACGTCACCATTTTTTCCTGAAAACATACTTATAAAAGTGCTGTTGACTGGAAATTGTCCCTGAATGTTGGTAACAACCAAAAACATCCATATATGCAAGGAAAACAAATGTACTTAGTTAACAAATAAAGTTATGTGTAATAACATGAAATGATGCAGGGAAAAAGTGTTAGAACACATGAAGAAAGGGAGGTGAAGAAAGGCAATTAAGGCCCAGACTGCAGCTG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa43870
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077117 | Essential Splice Site | 130 | 1101 | 5 | 19 |
| ENSDART00000129476 | Essential Splice Site | 115 | 996 | 5 | 16 |
| ENSDART00000136032 | Essential Splice Site | 112 | 1060 | 4 | 17 |
Genomic Location (Zv9):
Chromosome 22 (position 31390207)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 22 | 28884316 |
| GRCz11 | 22 | 28833443 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCTGCTCTATAGCTTTCCAATATAATAAGCTAAATCTTTATATTCTTTT[A/G]GATGGCAGCCCCTCATATGGACATCACTCTCAGCGAGTTGCAAGAAATGG
Long Flanking Sequence:
ACATTTTCAGCAAAATGTGGACATAATGTAAAGTGTTCGAGATTAAGTAGATATATTTCATGCTAGGGCTGGAATAAATTGTGACAACGCAACAACTTTCTATTTAATCATTTAAAGACATTGCTAAATGATGTGGTAAGGGTTGATTATTCCACAACACTAGTATGATACACATAACTGCTTATATACCAAAATTTTACCATATTTGCCACAGTAAAACTACCTTTTGAGTCTAGAAAATCTAAGATAGATTCTTTATAGCAGGGGTGTCCTAACTCAGTCCTGGAGGGCCAGTATCCTGCAGATTTTAGCTTCAACTTGTTTCAGCACACCTGCAAGGATGTTTCTAGAAAGTATAGTAAGAGCTTGATTAGCTAGCCCAGGTGTGTCAGATTGTGGTTGGAACTAAACTTTGCAGGACACCGGCCCTCCAGCACTGAGTTTGGGCACCCCTGCTCTATAGCTTTCCAATATAATAAGCTAAATCTTTATATTCTTTT[A/G]GATGGCAGCCCCTCATATGGACATCACTCTCAGCGAGTTGCAAGAAATGGCTTCACGGCAACAGCAGCAGATTAACGCACAACAACAACTCCTGGCCACAAAGGTACTACACTATTTTTTTTACAACTTAAAAGGAGACTTGAAACATGAATTAATTTAAACCCAAAAGTAGATATTTAGCAGAGCATTCAAGCTGCTCTTTTCCATACAGTGTTAATACATTTTGTGCAAGGCTGTTTTTGGTGTCCATTCATTTCCATTGTTTGGAAAAGAGCAGTATTTCTTTTTAAGGTGCAATGGACTGATTCTTCCAATTCTCATGTCAGAAATACAGTATTGAATCCTGCTTATAGTGGGTCAAGTTGAACTAGAGGAGTTAAATTTGTGCTGTGACCAAGAAGGGAGCGAGAATTAAGGGGTTGCCTGTAAAGAAGTCCAGCTAGTTGAAGCTGTGTGACGCAAGCCTCATTTCCATGGCTATAGCACAATATTATACTGGT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa3156
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000077117 | Nonsense | 253 | 1101 | 7 | 19 |
| ENSDART00000129476 | Nonsense | 238 | 996 | 7 | 16 |
| ENSDART00000136032 | Nonsense | 235 | 1060 | 6 | 17 |
Genomic Location (Zv9):
Chromosome 22 (position 31392548)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 22 | 28886657 |
| GRCz11 | 22 | 28835784 |
KASP Assay ID:
554-2549.1 (used for ordering genotyping assays)
KASP Sequence:
AGCAGCGGGAGCTGGTGGTGGCCGTWAGCAGGGTGGAAGAGTTGAGTCGA[C/T]AACTRGACGTGTTACGTAGTGGAAAAWTGGACATGCCACACGAGGCTGGA
Long Flanking Sequence:
GAACAGAAACGCATCAGCAATAGCAAACTAGGTCAGAACCTGTAAACTCGAAGGGAAAAAGTAGGTTGGAAACACTGAAAAAGATTTAACATTAACCTTCATGTAGGAATATTAGTTCAAGGTGAAGCTTGTCATTTTTTGATCTATTAGTGGCACCAAATGGAATTGCAACTGGTTTGTTTGTGAATGAGGAGGCGGTTTTAAAAAGGTTTTTCAAAATCACTTGAGATATAATTTGTTGTAAATCATTGGCCCACTAATGGAAAAGATCATTCTAGCGTTTCTGTTATAAAAAATGCCATCAGCGACTAAATTAATCAGCAGAGACAACAACAAATGATCTTGCTTATGGGAATAAGAAGTTAATTAACAGTTGAATGATACACTTCGTTTTTCTCTCTCTCTCTGTAGTGGAGGAAATCGAGCAGATGAATGGTCTGTTCCAGCAGAAGCAGCGGGAGCTGGTGGTGGCCGTTAGCAGGGTGGAAGAGTTGAGTCGA[C/T]AACTAGACGTGTTACGTAGTGGAAAAATGGACATGCCACACGAGGCTGGACCGAGCTCCAGTGGAGAACTGGAGCGACTGTACAAAGAACTTCAGGTAACTCTTGCCAATTTTTGCAACACATGCAGTGCTATTGGGCACTTTTTAAAAGACATCTTCGAATCAAGTGGGATTTACATGTATTTTAATGAAAAAGGTTGGGGATTGAAAGTGATTGTCCAGTGCTCAAAATTCAACAGTGCCTCTTTTGTTCTGACATTCTCTTTTTTCTGCAGCTGAGGAATAAATTGAATCAGGAGCAAAGTGCCAAACTCCAGCAGCAGAGAGAGAATCTAAACAAGAGGAACGTAGAAATGGCCGCCATGGACAAAAGAGTGGCTGAACTGAGAGAAAGGCTGTGGAAGAAAAAAGCTGCTCTCCAACAGAAAGAGAACTTGCCTGTGAGCAACTTTCACGCTTTCCATATTTTTTGGACACAGATGTGATTTGTGTTTGCGCAGA
Associated Phenotype:
Not determined