Busch Lab

ZMP

LOC798599

Ensembl ID:
ENSDARG00000013210
Human Orthologue:
HTR2C
Human Description:
5-hydroxytryptamine (serotonin) receptor 2C [Source:HGNC Symbol;Acc:5295]
Mouse Orthologue:
Htr2c
Mouse Description:
5-hydroxytryptamine (serotonin) receptor 2C Gene [Source:MGI Symbol;Acc:MGI:96281]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa5962 Nonsense Mutation detected in F1 DNA Not yet available
sa24033 Essential Splice Site Available for shipment Available now
sa43720 Nonsense Mutation detected in F1 DNA Not yet available
sa12052 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa5962
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036537 Nonsense 101 355 2 3
Genomic Location (Zv9):
Chromosome 21 (position 42020757)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 43619803
GRCz11 21 43614979
KASP Assay ID:
554-3868.1 (used for ordering genotyping assays)
KASP Sequence:
TATTGTTGTCTGCTTCCAGATCACACCTGGCCTCTCCCRCAGCYGCTGTG[T/A]CCGCTGTGGATCTTTCTGGACGTGCTTTTCTCCACAGCYTCCATCATGCA
Long Flanking Sequence:
GGATAAGTTGGCGGTTCATTCCACAGTGTTGGCCCCAGAATAATAAAGCAAATAAGCCGAAATGAAAATGAATGAATGAATGAATATCTGAAAATGGTGGCAAAGTGGTTAGCACTGTCACCTCAGAGCAAGAAGGTCGCTGGTTTGAGTCTCGGCTAGGTCAGTTGGCATTTCTGTATAGAGTTTGCATGTTCTCCCTGTCTTAGTATGGGTTTCTTCCGGGTGCTCTGGTTTCCCCCACAATACACAAGCACCATAGGGGAGGTGCATAAGCTAAATTGGTCACAGTGTATGTGTGTGAATGAGTGTGTTTGGGTGTTTCCCGGTGATGGGTTGCAGCTGGAAGGGCATTCGCTGTGTAAAACATATGTTGGATAAGTTGGCGGTTCATTCCGCTGTGGTGACTCCTGATTTATAAAGGGACTAAGCCGAAGAAAAATGAATGATTATTATTGTTGTCTGCTTCCAGATCACACCTGGCCTCTCCCGCAGCTGCTGTG[T/A]CCGCTGTGGATCTTTCTGGACGTGCTTTTCTCCACAGCCTCCATCATGCATCTCTGCGCCATCTCTCTGGACCGCTACATCGGCATCCGCAACCCATTCAGTATCAGTCACACTCAGTCATCTCGCAAGGCCATGATCAAAATAATCACCGTGTGGACCATTTCTATAGGTGAGAGAAGCATTCAGTGGTGAGAGTTACAATAATGGGTAACACTTTACAATAACAGTACATGAATAATGATGTATTAATAAGTAAACTAAACATTACTTTATTATGAATCAATGATTAGTTAAGGTATACACTAATCAAGAATAACTACATCATGAGTTACATGAGTTCATGTGTGAATAACGGCTACCTTAATCACTTGTTAGTACATGTTGTTAATTAATGTATTAATTAACATTTAAGTTTAAGCTAAATGTAACCAACATGAACTCATGAGCTGTTAATGTATAGTTATATCATGACTTTACTTGGAGGGGCACATCACTATTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24033
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036537 Essential Splice Site 158 355 2 3
Genomic Location (Zv9):
Chromosome 21 (position 42020586)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 43619632
GRCz11 21 43614808
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTCGCAAGGCCATGATCAAAATAATCACCGTGTGGACCATTTCTATAGG[T/A]GAGAGAAGCATTCAGTGGTGAGAGTTACAATAATGGGTAACACTTTACAA
Long Flanking Sequence:
TTCTGTATAGAGTTTGCATGTTCTCCCTGTCTTAGTATGGGTTTCTTCCGGGTGCTCTGGTTTCCCCCACAATACACAAGCACCATAGGGGAGGTGCATAAGCTAAATTGGTCACAGTGTATGTGTGTGAATGAGTGTGTTTGGGTGTTTCCCGGTGATGGGTTGCAGCTGGAAGGGCATTCGCTGTGTAAAACATATGTTGGATAAGTTGGCGGTTCATTCCGCTGTGGTGACTCCTGATTTATAAAGGGACTAAGCCGAAGAAAAATGAATGATTATTATTGTTGTCTGCTTCCAGATCACACCTGGCCTCTCCCGCAGCTGCTGTGTCCGCTGTGGATCTTTCTGGACGTGCTTTTCTCCACAGCCTCCATCATGCATCTCTGCGCCATCTCTCTGGACCGCTACATCGGCATCCGCAACCCATTCAGTATCAGTCACACTCAGTCATCTCGCAAGGCCATGATCAAAATAATCACCGTGTGGACCATTTCTATAGG[T/A]GAGAGAAGCATTCAGTGGTGAGAGTTACAATAATGGGTAACACTTTACAATAACAGTACATGAATAATGATGTATTAATAAGTAAACTAAACATTACTTTATTATGAATCAATGATTAGTTAAGGTATACACTAATCAAGAATAACTACATCATGAGTTACATGAGTTCATGTGTGAATAACGGCTACCTTAATCACTTGTTAGTACATGTTGTTAATTAATGTATTAATTAACATTTAAGTTTAAGCTAAATGTAACCAACATGAACTCATGAGCTGTTAATGTATAGTTATATCATGACTTTACTTGGAGGGGCACATCACTATTAACTCATCCTTAACTACTCATGAACTCCTGTTCATGTTGATGTTGACCAACACTTATCTGGTGTTATTCAGTTTAAACCAAGCGGCAACCTCCCGCTCTCCCTCAGGAAGCCAATACGGAAGTAACTAAAACTGCAATTCATCCGAAATTCCGCTAGTCCTGGCCGCTCCTGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43720
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036537 Nonsense 312 355 3 3
Genomic Location (Zv9):
Chromosome 21 (position 42015362)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 43614408
GRCz11 21 43609584
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCATCACCAATGTGCTGAACGCCATCTGTCGGGACAACTGTAGCGAGTA[T/A]GTTCATAAACTCCTCGATATTTTCGTCTGGGTGGGATACGTCTCGTCTGG
Long Flanking Sequence:
GTACTTCACATTTGTTGTTGTTTTTTCTGTCTTCCAGTGTTGTCCCTGCCCATTCCAGTGATGGGTTTGCAGGATGAGCAGAAGGTGTTTATAGACTGCGCGTGTGTCCTGAACGAGCCTCGCTTTATCCTCGTTGGCTCCATCGTGGCCTTCTTCGTTCCTCTGGTCATCATGGTGGTCTGCTATTACCTCACTCTCCATCATCTCCAGAAACACAGCAAGTCCTTCCCGCACGACAGCAAGAGCTCCTGCATGCATTCGTCCATCGAAACAAGTGACACAAGCTTCCTAAACAGCAAGTCCTCCTCCAAAATGTCAGCGTTTCCGGTTATCAAACGCTCGCCGCTCAAAAGCAGACAAGGCATGAATCGAGCTTTGGAAAATGAACGGCGAGCCTCCAAAGTCTTGGGGATCGTCTTCTTTCTGTTCCTGATCATGTGGTGTCCGTTTTTCATCACCAATGTGCTGAACGCCATCTGTCGGGACAACTGTAGCGAGTA[T/A]GTTCATAAACTCCTCGATATTTTCGTCTGGGTGGGATACGTCTCGTCTGGAGTGAACCCCCTGATTTACACCCTTTTCAACAAGACGTACCGCCAAGCCTTCGCTCGATACCTTCGCTGTAAATTTCACTAGGAAACACCACAGGAGAAGTCTGAGGTCAGCGGACATCATGGCAGTCTAAGTGCTAAATGACTATCACAAACACTGTCAATGTTTTTTTTTTATTTCCTATCAACATTTACATTTAGCAGACGCGTTTGTCCAATGCAACTTACAATTACGGAGGCATTCTGCGACTAGACAAGAAGAGGCAATACAAACAAGAAGTGCTGCTTATACACATGAACTGTCAGTGCTCTGGGAATTAAATGCTGGAGTAAAGAGCGGGGAGTGTTTTTATAGTGTTTCTACAGGTGGTTTGTCAAGCCCACTCACCTGTGTGAAGCACACTTCCAAATGCAGACATGAAGGCTGCGTCCGAAACCGCCTACTACTCAGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12052
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036537 Nonsense 348 355 3 3
Genomic Location (Zv9):
Chromosome 21 (position 42015256)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 43614302
GRCz11 21 43609478
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACCCCCTGATTTACACCCTTTTCAACAAGACKTACCGCCAAGCCTTCGCT[C/T]GATACCTTCGCTGTAAATTTCACTAGGAAACACCACAGGAGAAGTCTGWG
Long Flanking Sequence:
TCCTGAACGAGCCTCGCTTTATCCTCGTTGGCTCCATCGTGGCCTTCTTCGTTCCTCTGGTCATCATGGTGGTCTGCTATTACCTCACTCTCCATCATCTCCAGAAACACAGCAAGTCCTTCCCGCACGACAGCAAGAGCTCCTGCATGCATTCGTCCATCGAAACAAGTGACACAAGCTTCCTAAACAGCAAGTCCTCCTCCAAAATGTCAGCGTTTCCGGTTATCAAACGCTCGCCGCTCAAAAGCAGACAAGGCATGAATCGAGCTTTGGAAAATGAACGGCGAGCCTCCAAAGTCTTGGGGATCGTCTTCTTTCTGTTCCTGATCATGTGGTGTCCGTTTTTCATCACCAATGTGCTGAACGCCATCTGTCGGGACAACTGTAGCGAGTATGTTCATAAACTCCTCGATATTTTCGTCTGGGTGGGATACGTCTCGTCTGGAGTGAACCCCCTGATTTACACCCTTTTCAACAAGACGTACCGCCAAGCCTTCGCT[C/T]GATACCTTCGCTGTAAATTTCACTAGGAAACACCACAGGAGAAGTCTGAGGTCAGCGGACATCATGGCAGTCTAAGTGCTAAATGACTATCACAAACACTGTCAATGTTTTTTTTTTATTTCCTATCAACATTTACATTTAGCAGACGCGTTTGTCCAATGCAACTTACAATTACGGAGGCATTCTGCGACTAGACAAGAAGAGGCAATACAAACAAGAAGTGCTGCTTATACACATGAACTGTCAGTGCTCTGGGAATTAAATGCTGGAGTAAAGAGCGGGGAGTGTTTTTATAGTGTTTCTACAGGTGGTTTGTCAAGCCCACTCACCTGTGTGAAGCACACTTCCAAATGCAGACATGAAGGCTGCGTCCGAAACCGCCTACTACTCAGTAGGTACTGCATTTGAATTTAAACGTACTACTCGGCCGTTAGAAAAGTATGTTCTATACAGTATGAATGTGAAAAGTATGAATGGAATTCGGACATACTACATCCGCC
Associated Phenotype:
Not determined