Busch Lab

ZMP

usp28

Ensembl ID:
ENSDARG00000008880
ZFIN ID:
ZDB-GENE-041008-142
Human Orthologue:
USP28
Human Description:
ubiquitin specific peptidase 28 [Source:HGNC Symbol;Acc:12625]
Mouse Orthologue:
Usp28
Mouse Description:
ubiquitin specific peptidase 28 Gene [Source:MGI Symbol;Acc:MGI:2442293]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa43643 Nonsense Mutation detected in F1 DNA Not yet available
sa18009 Nonsense Available for shipment Available now
sa1020 Essential Splice Site, Missense Available for shipment Available now
sa23935 Nonsense Available for shipment Available now
sa16609 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa43643
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003076 Nonsense 302 1163 10 26
ENSDART00000147896 None None 1041 None 23
Genomic Location (Zv9):
Chromosome 21 (position 22213188)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 23061601
GRCz11 21 23098206
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCATGCAATTGTGTGCAGGAGAGATTGTGTCCAACATCGAGCAATTCGGA[C/T]AATACCCTCTCCAAGTGAACGGCTTCAATAATTTAGATGAATGTTTGGAG
Long Flanking Sequence:
ATTTTAAAAACAGTGGGACTAGGATAAAGCTTTTTAATGGTTTGTTTAAAATCATTTTATTGCCATCTAACATGCATCATCTGCTTGCAACATTAAGAAAATGTGTTTGTTACCCCGAGGCAACATCTTGCTGTAGAGTGTTAATTAATAAATGGTAATGAGTGCAGCATTTGTTAAAGAATCATGAATAATTACCCTATGGTATATTTGGTTGCTAATGTACTTGCCAGGAATTTTTTTTCTTTTTTTTTTGTTTTTTTTTTGTTTGGTCTCTGAAAATAAAACATGGCAGCTGTTATTTTCAGTAACCCAGAGGATAAACAAAACAACCCCATGGTCCAGCTGTTTTATGGCACATTTGTGGCTGAGAGGCTTCATGAAGGTAAGAGAATGACATTTCTTCTGTAATTATTCTGTATTTATCACCCTCATTATCGACGATATTTACATGCATGCAATTGTGTGCAGGAGAGATTGTGTCCAACATCGAGCAATTCGGA[C/T]AATACCCTCTCCAAGTGAACGGCTTCAATAATTTAGATGAATGTTTGGAGGGGGCAATGGTTGAGGGAGAGATTGAGTCTCTTCATTCAGATCAGACACTCTCCTCCGGCCAAGAGGTCAGTTTTACCTCGTGCTACAGTTGTATGGACGTCGTGGGTTTATTTATTAATGTGAAGTATGCACATGCTGCTATTATGGATTCAGGTTTGTGTCTTTGTTCACAGAGGTGGTTCTCCAAGCTGCCGCCAGTGTTGACCTTTGAACTGTCCAGATTTGAGTTCAATCAGTCTTTGGGGCGACCCGAAAAAATACACAAAAAACTGGAGTTTCCCCAAGTGATCTACATGGACAGGTTAGAAAAACAAATCTTGTTGACAGTGTAAATTGTTCAGTGTTCATTACTACAGCTTCTTTATTTGTTTGTTTGTTTGTTTATCTTTTTATATAGAAATGGATTTATGTACTTTTAAGTCATGGTTAACATTGTCCAACATCATTAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18009
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003076 Nonsense 365 1163 11 26
ENSDART00000147896 Nonsense 243 1041 8 23
Genomic Location (Zv9):
Chromosome 21 (position 22212891)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 23061304
GRCz11 21 23097909
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGTGTTGACCTTTGAACTGTCCAGATTTGAGTTCAATCAGTCTTTGGGG[C/T]GACCCGAAAAAATACACAAAAAACTGGAGTTTCCCCAAGTGATCTACATG
Long Flanking Sequence:
ATTTTCAGTAACCCAGAGGATAAACAAAACAACCCCATGGTCCAGCTGTTTTATGGCACATTTGTGGCTGAGAGGCTTCATGAAGGTAAGAGAATGACATTTCTTCTGTAATTATTCTGTATTTATCACCCTCATTATCGACGATATTTACATGCATGCAATTGTGTGCAGGAGAGATTGTGTCCAACATCGAGCAATTCGGACAATACCCTCTCCAAGTGAACGGCTTCAATAATTTAGATGAATGTTTGGAGGGGGCAATGGTTGAGGGAGAGATTGAGTCTCTTCATTCAGATCAGACACTCTCCTCCGGCCAAGAGGTCAGTTTTACCTCGTGCTACAGTTGTATGGACGTCGTGGGTTTATTTATTAATGTGAAGTATGCACATGCTGCTATTATGGATTCAGGTTTGTGTCTTTGTTCACAGAGGTGGTTCTCCAAGCTGCCGCCAGTGTTGACCTTTGAACTGTCCAGATTTGAGTTCAATCAGTCTTTGGGG[C/T]GACCCGAAAAAATACACAAAAAACTGGAGTTTCCCCAAGTGATCTACATGGACAGGTTAGAAAAACAAATCTTGTTGACAGTGTAAATTGTTCAGTGTTCATTACTACAGCTTCTTTATTTGTTTGTTTGTTTGTTTATCTTTTTATATAGAAATGGATTTATGTACTTTTAAGTCATGGTTAACATTGTCCAACATCATTACTATTGATTTATTTATTTTCATATTTATTATTATGAATGTCCCTGTTTGTCTGGTTTTAGATTGATGTATGTTTGTTTGTTTGTTTGTTTGTTTGTTTGTTTGTTTTATTGACTGATTTATTTTATTTTAATTTATTATCTTATTTATTGATTTATTTAATTTAATTTGTTTTCTTATTTATTCATTTAATTTATTTAATTAATTTATTTATTTGCTTGTTTATCTTTAGTAGCAGACTTTATTTTATTATTTATTTTATTTATCAGTTTATTTATTTATTTGCCCATTTTTTCATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1020
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site, Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003076 Essential Splice Site 466 1163 14 26
ENSDART00000147896 Missense 344 1041 11 23
Genomic Location (Zv9):
Chromosome 21 (position 22210496)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 23058909
GRCz11 21 23095514
KASP Assay ID:
554-0924.1 (used for ordering genotyping assays)
KASP Sequence:
GTTTTCTCCTCTGTGTTTGTCCRCCTCTAAATGTTTAATTTCTTGTTGTA[G/A]TCAAACAGAAGCAGATGATGCCGGCTCGTCAGATGGTTCGGGCTGCCCGC
Long Flanking Sequence:
GAACTATCCCTTTGAGAGCATATAGTTCAGTGGTAAATAGCAATTCTTTACATTTTGTACACAGATACCTTCACAAAAATGTCAATCAGACTCACGGCAGGAGAGGAGAGGTCAAGAGACTCAAGGACCAGTTAACACTTCTACAGCAGAAGCTTGAGGGGTATGTTTATTCCCTGCAACATATTGAGTAATCTATAAATATTGCTCTTCCTGGTTTAAAATATAACTTTCTTTTTAAAGATATAAAAACTACGGCTCAGGGCCAGCCAAATACCCTCTGGCAGACATGTTGCAGTATGTCCTAGAGTTTGCCACCACAAAACCCACAAATCCAGGTTCACCAGTACCTACAAACCCTCCCATAAGCACAGATCCCAGCTCAGGTGACAGCAGGCAAGACCCACTTTCCTCAGCTCTCCTTCATCCGTGGATAAACTGTGCCCATTGTTTGTTTTCTCCTCTGTGTTTGTCCGCCTCTAAATGTTTAATTTCTTGTTGTA[G/A]TCAAACAGAAGCAGATGATGCCGGCTCGTCAGATGGTTCGGGCTGCCCGCCGACAGCGACGCAGAGAACGCCCATCCACAAGCCTTTTACTCAGTGCAGACCCCCTATGGAGGTGCCAGTGCAGCCGGCGCCACACAGCGTGAGCGAGGAGGAGCTGCACTTCATCAGGAGCTGCTTACAGCGCTGGAGAGCTGAAGTGGAGAACACTATAAGTGGTACATCCCTCACTGGGTCAAGGATGCTTTTCTTACTATTACGCTTCCATTACCTTGTTTTGAAGTGAATATATATACAGTTGAAGTCAAAATTATTAGCCATCCTGTGATTTTTCTTGTCTTTTTTAAATATTTCCCAGATTATGTTTAACAGAGCGCAGGATTTTTCACTGTATTTCCTGAAATATTTTTTGCTTCTTAATAGGTCTATTTCCCAGAGATGGGTTGCAGCTTAAAGGGCATTCGCTGTGTAAAAACATGCTGGAAAAGTTGGCGGTTCATTCC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa23935
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003076 Nonsense 960 1163 22 26
ENSDART00000147896 Nonsense 838 1041 19 23
Genomic Location (Zv9):
Chromosome 21 (position 22170867)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 23019280
GRCz11 21 23055885
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTCTCTTCACAGGGCCGTCAGCATCATGAGAGAGGCCAGATCGAAACTT[C/T]GACTAATTAGACCAGAAGATATGGACATGGATGAGTATTTGGTAAAATCA
Long Flanking Sequence:
CGGAGCTAAACAAACAGTGATGTAAAAGCAGGCGGAGTTTAGTCACTCCGTTATTAAGTAATAAAGAGGCTCATTCCACCCCCATAAGCTGTTTTCAGGCTAACAAGGAAGCTCTGAATTCTGAAACTTAAGAGATGTTTGTGTAGTGCTGTGACATCTTATATGTCAAAAGGAAGTTTATTTCGCATGTCCTATTTGAGATTGACTATTTAGATGAATCTAGTTAATCTAAATCTAATGTAATCATGTCTTTTTCTACATATAATTAAGATACTGTGTGCTTAATTAGAAGTAAAATATTTTGTTTTTGCAATGCCACATTTGTTAGAGTTTTGCACTTTGTCACATGAGTCTGAAAGCTTTGTCTGATAAACCCCTAAGTTTGACAATGTAGTTTCTCTGTTCGTGTCACATTTGAGATAGACTGTTTAGATTAATCTGCACTGGATGTTTCTCTTCACAGGGCCGTCAGCATCATGAGAGAGGCCAGATCGAAACTT[C/T]GACTAATTAGACCAGAAGATATGGACATGGATGAGTATTTGGTAAAATCAATGAGACTCACTAATCTAAAAATAAAATACATTCATACTTATATCATCAAGGATGCATACAAATGTTGATCGAAAGAGACTTCTTTCTTATACGCTTTTACGAAACCTCACTCTCAATCTATTGAATGTTAATGTCTGAATTTGACATTGTTGAAGAGTAGCTACTGTAGAAACAAGTTGCACCGTTACTAGCTGAGCTACCTTTTTGGTCACACTTTTTTTTAATGGTCCGTTTGTTGAATTAAGTTACATTACATCTACATGCCAACTAATTCTCATTAGATTATAAGTAGACTGTTAGGTTGGGGTTAAGGTTAGTGTAAGTTGATATGTACTTGCAAAGTCAGTTCTTTTAGTCAGTGAAATGTGTTAAAGGAGCAGTATCAACAGATATTAAGCAGACAGTCTACTATTACTCAAATGGACCATCAAAATAAAGTGTTACCACAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16609
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003076 Nonsense 1069 1163 25 26
ENSDART00000147896 Nonsense 947 1041 22 23
Genomic Location (Zv9):
Chromosome 21 (position 22167524)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 23015937
GRCz11 21 23052542
KASP Assay ID:
2261-5620.1 (used for ordering genotyping assays)
KASP Sequence:
AGTCAGGATGAGAGTGACGTGACGGAGGGAGAGAGCCTCATGAATGAGTG[T/A]GYGATCCCTTGCATGCACCTCATGGTTCGAGACAGTGTCAGCCAAGAGGA
Long Flanking Sequence:
TGTTTTATATTAGTGCATATTTTACAATAAATACTATTTTTATCATTTAGTTAAAAACAAATTATATTTTATTCATTGTTGTGATTTCTGTTTTATTCTGATTCATGTATTAGCAATTTAAACTTACAAAAAGTAAAAAAAAAAAAACAAGTCTGATTCTTTAAAAATGATTGTAAACACTTATTTGTGCCTAGAAATGGTTTCTTATTGTCAGTGTTATAAACTGTAAAAAAGAAAAAAAAAAGTTTGTTTCGGAAATCTTTGATGAATTAAGTATAATATATGTATATAATATAAGTAAATAGTACTTATTTGAAACATTATTTGGTCTTCATTTCTAATTTGAAGAATTTAGGGCTCAAGCTTTACACAAAGACTTTTTAGGTTCAACTGATACATTTGCACTCTGATATGCAGGAGCTGAATGAGAAGGCAGCCACGCTGTTTAAAAGTCAGGATGAGAGTGACGTGACGGAGGGAGAGAGCCTCATGAATGAGTG[T/A]GTGATCCCTTGCATGCACCTCATGGTTCGAGACAGTGTCAGCCAAGAGGACCTGGATGTCATCGAGCTGATCAGGAATTGCTGGTGCTCCTACCTGGGGCAGGACATGGATGGTGGGCTTTTTCACCATTTCAATTAGATCAAGGATTTTTAAACTGTGGTCAGGAGGCTGCAAGAGAGGGCCTTTGGAAATGTAAAAAAACTGAATAGACACTTAATAGAAAAGTTTTTTTTTTTTTTCAAAATAGTAATAAATTAGTTAATAAGATGTATTAAAATAATAATACAATCATATTTTTAACTTATTTATATTTATGAATATATTTATAATTAATGAAATACTTAATAATTGTTTAATTGGTAAATATAAACTGTAATAAAAGAAACAAACATACACTGTACCTACAAATTACTTTCAAAGAAATAATTATACTAATTCTGAAATCATTTAGGGCGATGCGGTGGCACAGTGGGTAGCACGTTTGCCTCACATCAATAAGG
Associated Phenotype:
Not determined