ZMP
si:dkey-246j23.5
Ensembl ID:
ZFIN IDs:
Description:
LOC570832 protein [Source:UniProtKB/TrEMBL;Acc:Q498V9]
Human Orthologue:
C7
Human Description:
complement component 7 [Source:HGNC Symbol;Acc:1346]
Mouse Orthologue:
C7
Mouse Description:
complement component 7 Gene [Source:MGI Symbol;Acc:MGI:88235]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa43624 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa39327 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa43625 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa23912 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa43624
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079718 | Nonsense | 219 | 833 | 7 | 18 |
| ENSDART00000132741 | Nonsense | 220 | 834 | 7 | 18 |
Genomic Location (Zv9):
Chromosome 21 (position 19734784)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 20870273 |
| GRCz11 | 21 | 20906909 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCACTGATGACTACTATGACAGTTCCTGGTCCTACATGAGGGATGAAAAG[C/T]AAAGAAGGATCATTCGGGGAGGCCATGATCATAAAACCTTTCATAACCAA
Long Flanking Sequence:
AAACAAAAGATGTATTATAAAATCTGGGGCCCCCTTCTTAGATGTAAATGTTAATAATGCCTGTAATTATTTATTTTTCTAAAATATTTTTTTTCTTTCCTTTTACATGTCATTTTATTTTGTTTTGTTTCTGATTCGATTAGTCTGGCTGGGATGTATTATTTTAATGATAATACTGTATAATTGCAGTATTGTTTGCTAGTGTTTTGGTGCATGTTCTAGTTGGTATCTGGTAAAAACACTGAGATAATCGTGTTAAATAAATACATGATGTTCTCTAGTGGGTATTAAGTTTTATAAAAACTTTTATAAATAAAGTATAAAAAAAAGAATTTGGAGCAAAAAGTGTAAATATGCTGCAATTACTTAATGTACTATTAATATTTAGTTATTTCTCCTCCTTGTTATATAAACATTTTGTTTCCTTTTAGGTCAGTGTTGAAAACGATTTCACTGATGACTACTATGACAGTTCCTGGTCCTACATGAGGGATGAAAAG[C/T]AAAGAAGGATCATTCGGGGAGGCCATGATCATAAAACCTTTCATAACCAACTTAAACAGGACAAGGTAACAATGCATTCAATATATTAAACAGTAGAAAAGACTTGTTATAATGATATATTTAAAGAGTGTTTTTCTGTTTTTAAAGACCTATCACCTGCTGATAATAAGAAATGAGGTAGAAGTGGCTCAGTTCCAGAACAACGCTCCGGAATACTTGCCTCTGTCTGAAGATTTTTGGAAGGATCTATCAGCTCTGCCCATCACATATGAGCCATCAGCCTATCGACTATTCATACAGCGATATGGTACTCACTATATGGAGGAAGGATCTCTGGGGGGCCAGTATAGGGCACTGCTGGAGCTGGACGCAAATTATATGATGGAAATGAGTATGTGTTAATTTTCTCTTTTCTCTGGTAATATTAATTGTGAAATAATAGGGTATATAAACTGCATTACAAGTAGCGTGATTTACGCAATTACTTTTCTTAGTAACGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa39327
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079718 | Essential Splice Site | 241 | 833 | 8 | 18 |
| ENSDART00000132741 | Essential Splice Site | 242 | 834 | 8 | 18 |
Genomic Location (Zv9):
Chromosome 21 (position 19734931)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 20870420 |
| GRCz11 | 21 | 20907056 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAAAGACTTGTTATAATGATATATTTAAAGAGTGTTTTTCTGTTTTTAAA[G/A]ACCTATCACCTGCTGATAATAAGAAATGAGGTAGAAGTGGCTCAGTTCCA
Long Flanking Sequence:
GCTGGGATGTATTATTTTAATGATAATACTGTATAATTGCAGTATTGTTTGCTAGTGTTTTGGTGCATGTTCTAGTTGGTATCTGGTAAAAACACTGAGATAATCGTGTTAAATAAATACATGATGTTCTCTAGTGGGTATTAAGTTTTATAAAAACTTTTATAAATAAAGTATAAAAAAAAGAATTTGGAGCAAAAAGTGTAAATATGCTGCAATTACTTAATGTACTATTAATATTTAGTTATTTCTCCTCCTTGTTATATAAACATTTTGTTTCCTTTTAGGTCAGTGTTGAAAACGATTTCACTGATGACTACTATGACAGTTCCTGGTCCTACATGAGGGATGAAAAGCAAAGAAGGATCATTCGGGGAGGCCATGATCATAAAACCTTTCATAACCAACTTAAACAGGACAAGGTAACAATGCATTCAATATATTAAACAGTAGAAAAGACTTGTTATAATGATATATTTAAAGAGTGTTTTTCTGTTTTTAAA[G/A]ACCTATCACCTGCTGATAATAAGAAATGAGGTAGAAGTGGCTCAGTTCCAGAACAACGCTCCGGAATACTTGCCTCTGTCTGAAGATTTTTGGAAGGATCTATCAGCTCTGCCCATCACATATGAGCCATCAGCCTATCGACTATTCATACAGCGATATGGTACTCACTATATGGAGGAAGGATCTCTGGGGGGCCAGTATAGGGCACTGCTGGAGCTGGACGCAAATTATATGATGGAAATGAGTATGTGTTAATTTTCTCTTTTCTCTGGTAATATTAATTGTGAAATAATAGGGTATATAAACTGCATTACAAGTAGCGTGATTTACGCAATTACTTTTCTTAGTAACGAGTGAAGTAATGCATTACTTTAAAAATGATAAATATTTAAGTTACTTTTTTATTTAATGCAAGTTACTTTTTAGTTTAATTTATTGTTTTTCTTTTAATTGACGTAGTGGTTGGTGTGTCAACACGTGCACTCCAGTGCTCATGGCGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa43625
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079718 | Nonsense | 281 | 833 | 8 | 18 |
| ENSDART00000132741 | Nonsense | 282 | 834 | 8 | 18 |
Genomic Location (Zv9):
Chromosome 21 (position 19735054)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 20870543 |
| GRCz11 | 21 | 20907179 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTCTGTCTGAAGATTTTTGGAAGGATCTATCAGCTCTGCCCATCACATA[T/A]GAGCCATCAGCCTATCGACTATTCATACAGCGATATGGTACTCACTATAT
Long Flanking Sequence:
ATGTTCTCTAGTGGGTATTAAGTTTTATAAAAACTTTTATAAATAAAGTATAAAAAAAAGAATTTGGAGCAAAAAGTGTAAATATGCTGCAATTACTTAATGTACTATTAATATTTAGTTATTTCTCCTCCTTGTTATATAAACATTTTGTTTCCTTTTAGGTCAGTGTTGAAAACGATTTCACTGATGACTACTATGACAGTTCCTGGTCCTACATGAGGGATGAAAAGCAAAGAAGGATCATTCGGGGAGGCCATGATCATAAAACCTTTCATAACCAACTTAAACAGGACAAGGTAACAATGCATTCAATATATTAAACAGTAGAAAAGACTTGTTATAATGATATATTTAAAGAGTGTTTTTCTGTTTTTAAAGACCTATCACCTGCTGATAATAAGAAATGAGGTAGAAGTGGCTCAGTTCCAGAACAACGCTCCGGAATACTTGCCTCTGTCTGAAGATTTTTGGAAGGATCTATCAGCTCTGCCCATCACATA[T/A]GAGCCATCAGCCTATCGACTATTCATACAGCGATATGGTACTCACTATATGGAGGAAGGATCTCTGGGGGGCCAGTATAGGGCACTGCTGGAGCTGGACGCAAATTATATGATGGAAATGAGTATGTGTTAATTTTCTCTTTTCTCTGGTAATATTAATTGTGAAATAATAGGGTATATAAACTGCATTACAAGTAGCGTGATTTACGCAATTACTTTTCTTAGTAACGAGTGAAGTAATGCATTACTTTAAAAATGATAAATATTTAAGTTACTTTTTTATTTAATGCAAGTTACTTTTTAGTTTAATTTATTGTTTTTCTTTTAATTGACGTAGTGGTTGGTGTGTCAACACGTGCACTCCAGTGCTCATGGCGACCAGAGTTAAATTTTCGCCTCGCGGTCCTGTGCCGATCTTTCCTCTCTCTCCTCTCCCCATGCTTTCTTGTCAATACTCTCTACTGTCCTATCCATTAAAGGTGAAAACCCTGAAAAATAATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa23912
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079718 | Nonsense | 447 | 833 | 11 | 18 |
| ENSDART00000132741 | Nonsense | 448 | 834 | 11 | 18 |
Genomic Location (Zv9):
Chromosome 21 (position 19737831)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 20873320 |
| GRCz11 | 21 | 20909956 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACTAAAGAAAGTCCACCTGAAGAGGGCACTGGAGGCCTATCTGGAGGAG[C/T]AGAGCCCCTGTCACTGCAGACCCTGTCAGAACAATGGCATGGCTGTGCTC
Long Flanking Sequence:
TCTATAAGAAGAAAACAACCAAGTGTGTGAAACTGATGAAGACCATTGAGAATTTCAGTGGTTAGTAGCACATTATTACTGATGCTCTGACAAATTATTATCACTAAAGGTGTGTATAAATTTAGATTTGAATGTGGAACACTTTAAAATGTGTTACAGAGAACAGAAACCATAAGATGCCAATAAAAACAGACATTATAGGAGGAAATAGCGCTTATATCGCTGGCCTTAGTCTCCTGGACTTGGAAAACCCTGACAATAACAAACAAATGTACACAAAGTGGGCTGGGTCAGTGAAGGAGTTCCCTAAAGTAATAAAACAGAAGGTATGTCAGGCCTAAGGCATTAGAAATATGTACTTAAAAGTATAGAGTAAATATTTACACTATGATGTGTCTATTTCTTAGTTGAGGCCGCTGCATGAATTGGTCAAGGAGGTGGCATGTGCAGGACTAAAGAAAGTCCACCTGAAGAGGGCACTGGAGGCCTATCTGGAGGAG[C/T]AGAGCCCCTGTCACTGCAGACCCTGTCAGAACAATGGCATGGCTGTGCTCAGTGAAGGGGTTTGTACATGTGTGTGTAGGCCAGGAACCAGCGGTAATGCCTGCCAGAATGGCCATGTCCTTGGAGAGCAACCAGGTAGGACTTAATTAACTTTTGAAGTTTGCATGAAAATAAAATGAAAGTTTTTTGTGTGTGTGTTGGTATCAGTCTGTTAGTATTAATATTATCCAATAGCTACTGTGCTCCAAAACACATACACAATTGTCATTAGAAGATTTAGTGAAATAGTTTCTCACTTCTGTCATTTTGGGTCAGTGATTTTTAATGACATCACTTTTGCACTTTAGCTTATATGGTGGTCATATGTTTCAACAAAACAAATTCCCGGTTAGTGTTAAAATTATCCTTTAGGTTATCCATCTGTTAGTATTAAAGTTTTTATTTAGCTAATGTGCCCCAAAACAAAGGTAAAATTCTCATTAGAAGATTTGTCCGTCTTT
Associated Phenotype:
Not determined