Busch Lab

ZMP

mep1a.1

Ensembl ID:
ENSDARG00000029747
ZFIN ID:
ZDB-GENE-041001-209
Description:
meprin A, alpha.1 [Source:RefSeq peptide;Acc:NP_001025452]
Human Orthologue:
MEP1A
Human Description:
meprin A, alpha (PABA peptide hydrolase) [Source:HGNC Symbol;Acc:7015]
Mouse Orthologue:
Mep1a
Mouse Description:
meprin 1 alpha Gene [Source:MGI Symbol;Acc:MGI:96963]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa17730 Nonsense Available for shipment Available now
sa10535 Essential Splice Site Available for shipment Available now
sa13188 Essential Splice Site Available for shipment Available now
sa6643 Nonsense Mutation detected in F1 DNA Not yet available
sa31046 Nonsense Mutation detected in F1 DNA Not yet available
sa43495 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa17730
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047195 Nonsense 206 598 8 14
ENSDART00000122034 Nonsense 206 598 8 13
ENSDART00000130966 Nonsense 211 603 9 15
Genomic Location (Zv9):
Chromosome 20 (position 35501573)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 35574086
GRCz11 20 35476965
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTGTCACAGACCTAAACACACCATATGACTAYGAGTCTGTTATGCATTA[T/A]CGTCCATTTGCTTTCAACAAAGACCCCKCTATTCCTACTATTACMACCAA
Long Flanking Sequence:
CTATGTCTTGCCCTGTCTTCATGTTTCAGCTAAATTTATATCAGTCATTCAACCAGGGCCTGAGCAAGCTGAACTGCCGCTCTAGGCAAACGACAGTCATGCCACCCTTAACCCTAAAGTAAAAGTGGGGGGTGGGGTGGGGTTATAAATGAGGGCGCAGGTGGTAAGGGTAGTGTCGCGGACGCTGCCCTCTCTATTCTGGCCCCCTAGACGCGGATATAACTGAGGGTGCGGGTGGTGAGGGTAGGCTGCCGCCCTAGGTGGGTGTCTAGGTCGCCTCTATGGACGCGCCGTCCCTACATTCAACAAAGAGTTACATTTCAAAACACTTCATGTGATCTTTAAGAACACTCTGTTATAATTTTGTTTCATCATGTCTATAAAATCTCACATAATGCTTCCTTTTCTTTTCCAGGCTTGGAGCATAATTTTAACAAATATGATGACAGTTTTGTCACAGACCTAAACACACCATATGACTACGAGTCTGTTATGCATTA[T/A]CGTCCATTTGCTTTCAACAAAGACCCCTCTATTCCTACTATTACCACCAACATCCCAGAGTTCTACAAAATCATCGGACAATACCTGGACTTCAGTGAGATGGATATTGTCAGACTGAATCGAATGTACAACTGCTGTAGGTTAATAATACACAATAAGATAAATGAATTAACATGTTAGCTCGTATGTAACCTAGAAGTGGTCTGCTCTTCCACAGCCTCTTCTCTTACCCTGCTGGACCAGTGTGCTTTTGAAAAGATCAACATCTGTGGGATGGTACAGAGTTCGACTGATGATGGCGATTGGGTCCATCTTAAGAGCTCTGAGGATCATACTCTCAGCGGACAATGCAGAGGTGACAAAAAGGCCTGCAATACACATTTTCCAGAGTGGATGCAGTATGATTAAATTAAACAAACATTTTGGCTTGTGATTTCAGATTTAGGATATACTATGCACTTTGACACGTCCAGTGGACAGGCAGAGAGATCTGCTCTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10535
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047195 Essential Splice Site 525 598 11 14
ENSDART00000122034 Essential Splice Site 525 598 11 13
ENSDART00000130966 Essential Splice Site 530 603 12 15
Genomic Location (Zv9):
Chromosome 20 (position 35503746)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 35576259
GRCz11 20 35479138
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGGTTGAGGATGTCTTCTGCTCGTAGCCTCACCACTGACCTGAGCAAAGG[T/C]ATTTGAGGYCATWACCATGTTTGGGGAAACAATGGGGGAAAATCAACWTG
Long Flanking Sequence:
ATGAATGTGGTGATAAAGTGCCTTTCTTACCCAGCTGATGAAGACAAAACATGGAAGATTGCCCATGTGCCGATGCAAGTTGGGGCAAAATTCCGCTATGCATTCCAAGCAGTGAAAGGTGATTCGAGCAGCTCTGGAGGAGGTATATTCATAGATGACATCAGCCTAACAGAGACACACTGTCCAGCCGCTGTCTGGCGCATCCAAAACTTCTCCAGTATCCTTGAAAAGGCAGACTACAGCACTGTGCTGAACAGCCCTCGTTTCTACAGCCCTGAGGGTTATGGTTTTGGGATTCAAGTGATTCCACTGTCTGGCTATTCTGATTATGCTGGTAACTACACTGGTCTGTACTTCCATTTGATCAGTGGTGACAATGACATTGTGATGCAGTGGCCTGCTGTGAACCGCCAGGCCACTATAGTGGTGATGGACCAAGATCCGGATATTAGGTTGAGGATGTCTTCTGCTCGTAGCCTCACCACTGACCTGAGCAAAGG[T/C]ATTTGAGGCCATAACCATGTTTGGGGAAACAATGGGGGAAAATCAACATGTTTTAGAAACCAAAATGAAATAGAATGGTGAAGGAAATGTTAGATCTAATTTTAATTGGAAGCAATTATATTAAATTGATTGTAATAATTACAATTTAATTGAATTTATCTACATACATTTTAGGATAACTTAAACAAAATCCTCAAATTGGTTTGCATTACTGGATGTTTAACATTTGAATCATGAATTCTTGCTATATTAATTTTAACACAAGCTTGTGTGACCTTGTGTTTCTCTGACCGTCATATTTACATTATGTGAATGTGTGAGACCAAAAGGAGATCAAACATGGCCTCTATGTAAATACATTTTAAATATGGAGCAATTGTTCGTATATTAATGTTGCATCATCTTGTTTTTTTTCTTTCCCCTTTTCGCTGCATCGTCTGACAAAATTTCACATGCAGAGCTTTTGCACTGGAGTTTTTGCTTAGCATTTTTAAATTGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13188
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047195 Essential Splice Site 525 598 11 14
ENSDART00000122034 Essential Splice Site 525 598 11 13
ENSDART00000130966 Essential Splice Site 530 603 12 15
Genomic Location (Zv9):
Chromosome 20 (position 35503746)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 35576259
GRCz11 20 35479138
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGGTTGAGGATGTCTTCTGCTCGTAGCCTCACCACTGACCTGAGCAAAGG[T/C]ATTTGAGGYCATWACCATGTTTGGGGAAACAATGGGGGAAAATCAACWTG
Long Flanking Sequence:
ATGAATGTGGTGATAAAGTGCCTTTCTTACCCAGCTGATGAAGACAAAACATGGAAGATTGCCCATGTGCCGATGCAAGTTGGGGCAAAATTCCGCTATGCATTCCAAGCAGTGAAAGGTGATTCGAGCAGCTCTGGAGGAGGTATATTCATAGATGACATCAGCCTAACAGAGACACACTGTCCAGCCGCTGTCTGGCGCATCCAAAACTTCTCCAGTATCCTTGAAAAGGCAGACTACAGCACTGTGCTGAACAGCCCTCGTTTCTACAGCCCTGAGGGTTATGGTTTTGGGATTCAAGTGATTCCACTGTCTGGCTATTCTGATTATGCTGGTAACTACACTGGTCTGTACTTCCATTTGATCAGTGGTGACAATGACATTGTGATGCAGTGGCCTGCTGTGAACCGCCAGGCCACTATAGTGGTGATGGACCAAGATCCGGATATTAGGTTGAGGATGTCTTCTGCTCGTAGCCTCACCACTGACCTGAGCAAAGG[T/C]ATTTGAGGCCATAACCATGTTTGGGGAAACAATGGGGGAAAATCAACATGTTTTAGAAACCAAAATGAAATAGAATGGTGAAGGAAATGTTAGATCTAATTTTAATTGGAAGCAATTATATTAAATTGATTGTAATAATTACAATTTAATTGAATTTATCTACATACATTTTAGGATAACTTAAACAAAATCCTCAAATTGGTTTGCATTACTGGATGTTTAACATTTGAATCATGAATTCTTGCTATATTAATTTTAACACAAGCTTGTGTGACCTTGTGTTTCTCTGACCGTCATATTTACATTATGTGAATGTGTGAGACCAAAAGGAGATCAAACATGGCCTCTATGTAAATACATTTTAAATATGGAGCAATTGTTCGTATATTAATGTTGCATCATCTTGTTTTTTTTCTTTCCCCTTTTCGCTGCATCGTCTGACAAAATTTCACATGCAGAGCTTTTGCACTGGAGTTTTTGCTTAGCATTTTTAAATTGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6643
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047195 Nonsense 567 598 12 14
ENSDART00000122034 Nonsense 567 598 12 13
ENSDART00000130966 Nonsense 572 603 13 15
Genomic Location (Zv9):
Chromosome 20 (position 35505434)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 35577947
GRCz11 20 35480826
KASP Assay ID:
554-5336.1 (used for ordering genotyping assays)
KASP Sequence:
GACCATCAAAGGGATGGAATACTTTCATAAAGCACTACGATTTACACAGA[C/T]GAAATTACCTGAAAAATGATGACCTCATCATCTTTGTTGACTTTGAAGGT
Long Flanking Sequence:
TAAAACACTGTGATATAACCGCGCTCGGATCGGATCGCTTTCTCACTGTAATCGAACCGCTTCAGGGTTCGTTTCAATCGAGCCGAGACCACCTCACTCAAGCGATCTCGGAGCGATTACTTTGGCGCGGAACAGAGCGCGATTGCCCTGTTCACATATGCCAAACGAACCGCACTAACTGGGCAATCGAGACACGTTCCGAAACAAAAGTGTAGATGTGAAAGCACCCTGAGTCGATTAGAATTAGAACAATTAGAAATATTAGAGGAGGGGGGAGGCATTACTAGTTAAGGGGGACCTGTCCTTGTCAATTACTGTGACGTTTATGGCCTTGATAAAGATTGAAATTTTCATCTTTACATTAATGTTTTCTAGGAAATGGAGAACAACTATTGTGGGACAATCCAAAAAAGGTTGGGACCCTTGACCCAAGCGATGGTTTTTGGCGAGGACCATCAAAGGGATGGAATACTTTCATAAAGCACTACGATTTACACAGA[C/T]GAAATTACCTGAAAAATGATGACCTCATCATCTTTGTTGACTTTGAAGGTATGCTACACACTATATTAACCCCGCCCCTAACCCTAGCCCACACAGTGAGCGCATGTGTCTGAGAGTGCATGTGCAAGTCTGCAGCCAGACACTATTGGAGATGTTGTCTAATTGTTTGATTGTGTGTGTCTCTTTAAAGACTTAACAAGCCTGATAAAGAGTGAGGTTCCGACTGCCCCAAAGGTTTGAGGAAAAAAAGACTGTAAGTTGGCTGATTTAGAGTAAATACAACATTAAAATACACAACTATTATTTTTTTAATAGTTATCAGATTGAAAGGATTGATCACTCCAAACCAAACATTCTTACTATTTAATCCCTTTTAATCTTTCTTCAAAATGTCAACAGAAAAAAAAATAACTCAAAACATATTTGAAACAAGTGAAGGTGAGTAAATAATGTGTAAACGTTTTGTTTGTGGGTGAACTATCCCTTTACCCTCCTTTTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31046
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047195 Nonsense 569 598 12 14
ENSDART00000122034 Nonsense 569 598 12 13
ENSDART00000130966 Nonsense 574 603 13 15
ENSDART00000047195 Nonsense 569 598 12 14
ENSDART00000122034 Nonsense 569 598 12 13
ENSDART00000130966 Nonsense 574 603 13 15
Genomic Location (Zv9):
Chromosome 20 (position 35505442)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 35577955
GRCz11 20 35480834
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGGGATGGAATACTTTCATAAAGCACTACGATTTACACAGACGAAATTA[C/A]CTGAAAAATGATGACCTCATCATCTTTGTTGACTTTGAAGGTATGCTACA
Long Flanking Sequence:
TGTGATATAACCGCGCTCGGATCGGATCGCTTTCTCACTGTAATCGAACCGCTTCAGGGTTCGTTTCAATCGAGCCGAGACCACCTCACTCAAGCGATCTCGGAGCGATTACTTTGGCGCGGAACAGAGCGCGATTGCCCTGTTCACATATGCCAAACGAACCGCACTAACTGGGCAATCGAGACACGTTCCGAAACAAAAGTGTAGATGTGAAAGCACCCTGAGTCGATTAGAATTAGAACAATTAGAAATATTAGAGGAGGGGGGAGGCATTACTAGTTAAGGGGGACCTGTCCTTGTCAATTACTGTGACGTTTATGGCCTTGATAAAGATTGAAATTTTCATCTTTACATTAATGTTTTCTAGGAAATGGAGAACAACTATTGTGGGACAATCCAAAAAAGGTTGGGACCCTTGACCCAAGCGATGGTTTTTGGCGAGGACCATCAAAGGGATGGAATACTTTCATAAAGCACTACGATTTACACAGACGAAATTA[C/A]CTGAAAAATGATGACCTCATCATCTTTGTTGACTTTGAAGGTATGCTACACACTATATTAACCCCGCCCCTAACCCTAGCCCACACAGTGAGCGCATGTGTCTGAGAGTGCATGTGCAAGTCTGCAGCCAGACACTATTGGAGATGTTGTCTAATTGTTTGATTGTGTGTGTCTCTTTAAAGACTTAACAAGCCTGATAAAGAGTGAGGTTCCGACTGCCCCAAAGGTTTGAGGAAAAAAAGACTGTAAGTTGGCTGATTTAGAGTAAATACAACATTAAAATACACAACTATTATTTTTTTAATAGTTATCAGATTGAAAGGATTGATCACTCCAAACCAAACATTCTTACTATTTAATCCCTTTTAATCTTTCTTCAAAATGTCAACAGAAAAAAAAATAACTCAAAACATATTTGAAACAAGTGAAGGTGAGTAAATAATGTGTAAACGTTTTGTTTGTGGGTGAACTATCCCTTTACCCTCCTTTTTATCAGGGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43495
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047195 Nonsense 569 598 12 14
ENSDART00000122034 Nonsense 569 598 12 13
ENSDART00000130966 Nonsense 574 603 13 15
ENSDART00000047195 Nonsense 569 598 12 14
ENSDART00000122034 Nonsense 569 598 12 13
ENSDART00000130966 Nonsense 574 603 13 15
Genomic Location (Zv9):
Chromosome 20 (position 35505442)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 35577955
GRCz11 20 35480834
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGGGATGGAATACTTTCATAAAGCACTACGATTTACACAGACGAAATTA[C/A]CTGAAAAATGATGACCTCATCATCTTTGTTGACTTTGAAGGTATGCTACA
Long Flanking Sequence:
TGTGATATAACCGCGCTCGGATCGGATCGCTTTCTCACTGTAATCGAACCGCTTCAGGGTTCGTTTCAATCGAGCCGAGACCACCTCACTCAAGCGATCTCGGAGCGATTACTTTGGCGCGGAACAGAGCGCGATTGCCCTGTTCACATATGCCAAACGAACCGCACTAACTGGGCAATCGAGACACGTTCCGAAACAAAAGTGTAGATGTGAAAGCACCCTGAGTCGATTAGAATTAGAACAATTAGAAATATTAGAGGAGGGGGGAGGCATTACTAGTTAAGGGGGACCTGTCCTTGTCAATTACTGTGACGTTTATGGCCTTGATAAAGATTGAAATTTTCATCTTTACATTAATGTTTTCTAGGAAATGGAGAACAACTATTGTGGGACAATCCAAAAAAGGTTGGGACCCTTGACCCAAGCGATGGTTTTTGGCGAGGACCATCAAAGGGATGGAATACTTTCATAAAGCACTACGATTTACACAGACGAAATTA[C/A]CTGAAAAATGATGACCTCATCATCTTTGTTGACTTTGAAGGTATGCTACACACTATATTAACCCCGCCCCTAACCCTAGCCCACACAGTGAGCGCATGTGTCTGAGAGTGCATGTGCAAGTCTGCAGCCAGACACTATTGGAGATGTTGTCTAATTGTTTGATTGTGTGTGTCTCTTTAAAGACTTAACAAGCCTGATAAAGAGTGAGGTTCCGACTGCCCCAAAGGTTTGAGGAAAAAAAGACTGTAAGTTGGCTGATTTAGAGTAAATACAACATTAAAATACACAACTATTATTTTTTTAATAGTTATCAGATTGAAAGGATTGATCACTCCAAACCAAACATTCTTACTATTTAATCCCTTTTAATCTTTCTTCAAAATGTCAACAGAAAAAAAAATAACTCAAAACATATTTGAAACAAGTGAAGGTGAGTAAATAATGTGTAAACGTTTTGTTTGTGGGTGAACTATCCCTTTACCCTCCTTTTTATCAGGGCT
Associated Phenotype:
Not determined