Busch Lab

ZMP

ptpn23b

Ensembl ID:
ENSDARG00000070870
ZFIN ID:
ZDB-GENE-060503-179
Description:
protein tyrosine phosphatase-like [Source:RefSeq peptide;Acc:NP_001038393]
Human Orthologue:
PTPN23
Human Description:
protein tyrosine phosphatase, non-receptor type 23 [Source:HGNC Symbol;Acc:14406]
Mouse Orthologue:
Ptpn23
Mouse Description:
protein tyrosine phosphatase, non-receptor type 23 Gene [Source:MGI Symbol;Acc:MGI:2144837]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa45667 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa32240 Essential Splice Site Available for shipment Available now
sa43256 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa16423 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa45667
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104395 Essential Splice Site 96 1229 3 20
ENSDART00000122588 None None 166 None 7
ENSDART00000127876 Essential Splice Site 96 1229 3 20
Genomic Location (Zv9):
Chromosome 19 (position 18826137)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 19671372
GRCz11 19 19244325
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCGTGTTCCCATGGCAACTGGGCAGGAGGCTGCTCTGCCTGTGACATGG[T/C]AAAGATCATACTTGTTACAGTCAATGTGCATCATTTAAGTTTTTTTTTTT
Long Flanking Sequence:
AACAATAAATTATTTATTGTTAAATTACTTGAAATAAAATGATATAAAATACTGTTAGTACTACTAGCATCTTGCTTGACTTTGCCATTATTTGACTGTATGTCAGAAATACTGGTTTCAGAAAAATATGACAGTGTCTTTTCTTCCTCGTATGTCCTAGTACATTGAAATAAACTATGGTGAGAACCCGGAGAACTACAGCGAGGCACTGAAAAGACTGGAGCAGCTTAGACAAGTGGGTATATCAGTGGAATTATAGGAAATATAGTTACACACTTGCATATGGCTGCAGTTAATGAGTAATAGATAAAGGTTGATGATGATGAAGATGATGATGATAATAACTGCTTTGAAATCTCTCTCATTCTCAGAGTGTAGTAAACATCCCAAGGGATTTTGAGGGCTGCAACACTCTTAGAAAGTACTGTGGTCAGCTGCACTTTCTGCAGAGTCGTGTTCCCATGGCAACTGGGCAGGAGGCTGCTCTGCCTGTGACATGG[T/C]AAAGATCATACTTGTTACAGTCAATGTGCATCATTTAAGTTTTTTTTTTTTTTTTTTTATATTTTCTGCATTTCATCTTCTTTCAGGACAGATATCTTCACAGGGAGGAATATCACACATGAGGATATTAACTATGAGCATGCTTGTGTCCTTTATAACCTGGGTAATATAAATACAATCAAAGCATCAGCATAAAAAATCTAATCAAAACTTTGTCTCTGTTTTGCATAACAAACTGCAATTAAATTTGCTCTAATCTCTAATCTGTTTTAGGTGCTTTGCACTCGCTGCTGGGAGCTGTGGATAACCGCCTATCTGAAGAGGTGAACATGGGATTTATTCTAACTTATACTTAAAATACAACAAACAGTAACTGAAATAAAGTAAAATGTTCAATGTACAGAAGGTCAAATAATGAAAAATTAAACACGTCACCATTTTTCTCAGAAAATATAACATAAGATAACATAAATCAGGTATTAGAAATTAGTTATTAAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32240
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104395 Essential Splice Site 300 1229 10 20
ENSDART00000122588 None None 166 None 7
ENSDART00000127876 Essential Splice Site 300 1229 10 20
Genomic Location (Zv9):
Chromosome 19 (position 18828681)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 19673916
GRCz11 19 19246869
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTTTCAGTTCTCTCTTGACAAACTTAATGAGGCAATTAAACAGAGCAAG[G/A]TAACTGTTCCTAATCATCCACACACACAGCCCAGCCATTTCAACTTTTTA
Long Flanking Sequence:
ATTAATGTCAAGTCTCGTTTCAGGTGTGTGACTATTATAAGGATTGTCTCAGGGTGTTGGAGAATTCTGAATGTGTGCCAGGGAGGATTCAGAAAGAGTGGAGGAAACTCATTAACATGAAGATCAGCTACTTCAGTGCCATCACACATGTAAGACCATAACATTAACCATGCAGTGCTGTATACATTATACATTTCCTAAGACACATTATTTTAATAAATGTATTGTTTTATTTCCATTAGTTGCACATGGGAAAGCAGTCAGAGGAACAGCAGAAATACGGAGAAGCAGTAAGTGTATGCTTGTGTGCGTTTAGTGCACTTTTTGACTTGGCAGTTTGGTTCGCCAACTATGAAGTGAAAACATTATTAGGTGTACATTTTAAAACGTCCAACAGCTCTGTGGAATGTGAGCCCTCTGATGATAGTGTTGTTTGTCTGCAGGTTGCATATTTTCAGTTCTCTCTTGACAAACTTAATGAGGCAATTAAACAGAGCAAG[G/A]TAACTGTTCCTAATCATCCACACACACAGCCCAGCCATTTCAACTTTTTACAGACACCTTGATGATAAAATTGCCTTTGCTTGTATAGTGTTTTATTTAATCTCAACCAGTCAAATGCATGCATGTAAATACAGTATATAGATACATACATATATATAGTCAGTTATGTTATGATTAGAAATGTGTTGAAAAAAAACTTCTCTCCATTAAACAGAAATTGGGCAAAAAAGATAAACGGGGGCTAATAATTCTGACTTCAACTGTATGTGGTCTTGAATATTGGTTTTGAATATTAATCACCTTGTCTCAATCACAATATTCCCAATTGCTACCAAAGAAACTGGTGGTGTGGTGTATATTAAGCATATTTACATGTGCTTCACAGGGCCAACCAGAAACTATACAGGAAGCATTGAAATTCACAATGGATGTAATTGGTGGAAAGTAAGCCACTTCAATTGTGCATTTACATTTGTGGGGTCTAATATTTAAATCACATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43256
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104395 Essential Splice Site 658 1229 19 20
ENSDART00000122588 None None 166 None 7
ENSDART00000127876 Essential Splice Site 658 1229 19 20
Genomic Location (Zv9):
Chromosome 19 (position 18847469)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 19692704
GRCz11 19 19265657
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGTAACAGATTAGTTAATTTATTTATTAATCACCTTACTTTGTCCTGAA[G/A]ATGGAACACCACTGTGCAGGCTCTGATTGCCTCATTCGAGGCATATGAAG
Long Flanking Sequence:
TAGTACTCTTTCAGTTTTTGAAAACATTACTTAGTGAAATGATTGTTGCTAAGCTGTTTACAGTAATATTACTACAATATTATGGACTGAAAATGCTTTGTTCAGTGTCTTTTTAAACGGTTGTACAGTTAGTTATATCCGTCTAATGGGGGCATTAATGGCCCTTTAAAAACCACAGGATGTACTTTAAAAAGAGTAGGGGTTTGTCTCCGACATACTGACCAAACTTGCCCACTGGCCTTTGTCCGTCATGGCTTCCTAACCATCCCCATATCCTCTAATTGGCTTCATCACTCTTGTCTTCTCTCAGTCATTAAGCATGTTTGTGGCGTTTTGGTCTGGCACAGAAAAGCCTCTGTAGCATAATTCAGATTGAGGCACACTGATGGTGGTTGCGGAGATTCCCTGCATCTGTAAAATGCTTTGTGTATCCACAAAAGCACTATGTTAATGTAACAGATTAGTTAATTTATTTATTAATCACCTTACTTTGTCCTGAA[G/A]ATGGAACACCACTGTGCAGGCTCTGATTGCCTCATTCGAGGCATATGAAGAATTGATGAAGAAGGCTGAGGAGGGAAGAGATTTCTACCAGGATCTGGACAAGAAGACCTCTGGCTTGTTGGATCAAACAAAGTCCTATTGTCAAACCAGAGAGGCAGAGCGAGTTGCCTTGCTGGAGAGGTAAGATGTCTTGTGTAAAAAGATTTCGGTATGTGCATATGTGACTTTCAGAGTTGCTTTGAGGAAAGCCTGTACAATATAAGAAAATCATTTGCATATGCAACTAAATTTTATGGGGTGACTAAATGATTTCTAATGTTAGCCATTAGCTTACATTTCAGAATTTTTTTCACCAGTGATTGATTTGAATGTGTAGAATAAGTTTTTAGCAGATACATCTTCAAGTTCATGCTCTTGAACACACTTTCTATGTGTCTTGACAGTGCAGTAAGACCATTATGGGTATTATTACAGACTGTCTGTAATAATAGTACACTGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16423
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104395 Nonsense 1066 1229 20 20
ENSDART00000122588 None None 166 None 7
ENSDART00000127876 Nonsense 1066 1229 20 20
Genomic Location (Zv9):
Chromosome 19 (position 18851951)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 19697186
GRCz11 19 19270139
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGCACCACAGCAAGTACATTCCAGATCTCAACTCTTTTCACAAGCACCCT[T/A]GAACCAAAATTCCCAAGTTCCATATGGTCCTCGTCAACTCGGTCAGCCCC
Long Flanking Sequence:
ATCCTTGCCAAATTCCCAAATTGGGCAGCCAATACTAACTGGTCAACCTCAGTCTTCCTCTGCCCAACAAATAGTACAAGGCCAAAGCTTTACTCCCCAACCTATACAAAGCATCCATTCAACCTCACAAAGAGGTGCATTTTCTGGGCAAATCCTGCCACCCTTCTCACCTTTACAGGTTCAGCCCATCATGCCAGGTCAAACACAGCAACAATCTGGCCTCCCCTCAGGTTACCAACCAATGTTACTTCCACAAACCCAGCCCCAGCTTGGACCATCAGGCCAACTAACAGCATCCCAACCTCAGGGAGCCCTTATTCCAGGGCAAACTCAGCCTCACTTCAATCTTTCAAATCAGGCCCATCCTGGACAACTTCCACAAAACAGGCCCCAGCAATATATGGGTTACGCCACCACATCTTTTCCATCCTCACAACCTCTGCATATCTCTGCACCACAGCAAGTACATTCCAGATCTCAACTCTTTTCACAAGCACCCT[T/A]GAACCAAAATTCCCAAGTTCCATATGGTCCTCGTCAACTCGGTCAGCCCCAAATGCCACCAGGACCTATACCACCCCAGAACAACATGTATCCATTTGCACCAACACACATGGGCCAGCAACCTATGGGACAACAGCCAATTCCACCCCAATTCAATGCAATGTTTAATGGATCTGGGAGACAACCCATGCACCCTCCTGGTCAAAGCCAACTACTTGGTCCCCAACAACTGGCTTACCCGTCATCAGGACCAACAGTTGCGGCAGTGATGGACAATCCAGTTCCACCATCACTGGCCAACACACTCATACCTACTCCATCACCTCTTCAGGTTTCATCCCAGAGCCAGACCACTACTCCCACATCATCTTTTGCAACCCAGAATTTCAAGCCACAAACCACAAATGCTGCTCCAATCAACACGAACAATTTAGACTCTGCTACAGTTCTGGATTCTGTTCAAAGCAAGGTGGATAATCTCAGTATTGGCTGATTGTGGA
Associated Phenotype:
Not determined