Busch Lab

ZMP

si:ch1073-183g13.2

Ensembl ID:
ENSDARG00000061233
ZFIN ID:
ZDB-GENE-030131-8091
Description:
multidrug resistance-associated protein 5 [Source:RefSeq peptide;Acc:NP_001182542]
Mouse Orthologue:
Abcc5
Mouse Description:
ATP-binding cassette, sub-family C (CFTR/MRP), member 5 Gene [Source:MGI Symbol;Acc:MGI:1351644]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa43168 Nonsense Mutation detected in F1 DNA Not yet available
sa31027 Nonsense Mutation detected in F1 DNA Not yet available
sa43169 Nonsense Mutation detected in F1 DNA Not yet available
sa43170 Nonsense Mutation detected in F1 DNA Not yet available
sa2950 Nonsense F2 line generated Not yet available
sa32218 Nonsense Available for shipment Available now
sa43171 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa43168
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087070 Nonsense 150 1426 4 28
ENSDART00000135045 Nonsense 150 241 5 5

The following transcripts of ENSDARG00000061233 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 44227527)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 45816582
GRCz11 18 45813408
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCATAATAATACAACTCCTGCATTTCAACAGGCTGGCGGGACTGTGGGAA[G/T]AAGAAATCAGGTCACGAGGAGACGACGCGTCTCTTCGTCGTGTGGTCTGG
Long Flanking Sequence:
CTTGCCTCAACACACCTGCAAGGAGGTTTTTAGAAAGCCTAGTAAGAGCTTGATTAGCTAGCCCAGGTGTGTCTGATTGGGGTTGGAAGTAGACTTTGCAGGACACCGGCCCTCCAGGACCAAGCTTGGACATGCCTGTTATAGGCCATTCATTGATTTATAGACCAATAATAATACTTTAAAATCTATTCTGAATGTAACTGGGAGCCAGTGTGAAGACCTGAGGACAGGTGTGATGTGCTCAGATTGTCTGGTTCTGGTCAGAACCCTGGCAGCAGCGTTCTGGATAAGCTGCAAGTGTCTGACTGTCTTTTTGGGAAGGCCAGTAAAGGAGTCCATTACAGTAATCCACCCTGCTGGTCATAAAAGCATAAACAAGTTTTCAGTGGAAACAAAGCATCTAATTCTTGCTGTGATTTTGAGAAAATAGTATGCTACTGGTTTTGCATTGCATAATAATACAACTCCTGCATTTCAACAGGCTGGCGGGACTGTGGGAA[G/T]AAGAAATCAGGTCACGAGGAGACGACGCGTCTCTTCGTCGTGTGGTCTGGCATTTTTGCCGCACGCGTCTGCTGCTGTCCATCCTCTGCCTTATGGTTACTCAACTGGCAGGCTTCAGTGGCCCAGTAAGTAACACCATCTCAGCTCTGTGTCGTCTTTCTGGTGTCTTTTCTTCTTCTCCCTCTATCTACCTATCCATCTCTCTCCTACTCTGTCTTTCTCTATCTCTGTGTATTATTAGCATTGTAGATGCACCAATCAAATCCTGCATCCCCTCAGATGCTCAGGTGAGTGTTAAGATGGGGAAAGGAATGTGTTATTGTGTTTATATTGTCACTGGGCATCTGCTTTACCTCTGCGGTGTGTCCAGTGAGGCTCTCCAAACCAGATTATCAGCTTATTTTTTTTAAAGTGCCTTAATTATGTGTGCCAACACCAAAAGAGTATTACAGCTTTTCTGCTCCTTTTCTCTTAATAAAAAAACTGAAACAGGGAAATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31027
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087070 Nonsense 155 1426 4 28
ENSDART00000135045 Nonsense 155 241 5 5
ENSDART00000087070 Nonsense 155 1426 4 28
ENSDART00000135045 Nonsense 155 241 5 5

The following transcripts of ENSDARG00000061233 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 44227542)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 45816597
GRCz11 18 45813423
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCTGCATTTCAACAGGCTGGCGGGACTGTGGGAAGAAGAAATCAGGTCA[C/T]GAGGAGACGACGCGTCTCTTCGTCGTGTGGTCTGGCATTTTTGCCGCACG
Long Flanking Sequence:
CTGCAAGGAGGTTTTTAGAAAGCCTAGTAAGAGCTTGATTAGCTAGCCCAGGTGTGTCTGATTGGGGTTGGAAGTAGACTTTGCAGGACACCGGCCCTCCAGGACCAAGCTTGGACATGCCTGTTATAGGCCATTCATTGATTTATAGACCAATAATAATACTTTAAAATCTATTCTGAATGTAACTGGGAGCCAGTGTGAAGACCTGAGGACAGGTGTGATGTGCTCAGATTGTCTGGTTCTGGTCAGAACCCTGGCAGCAGCGTTCTGGATAAGCTGCAAGTGTCTGACTGTCTTTTTGGGAAGGCCAGTAAAGGAGTCCATTACAGTAATCCACCCTGCTGGTCATAAAAGCATAAACAAGTTTTCAGTGGAAACAAAGCATCTAATTCTTGCTGTGATTTTGAGAAAATAGTATGCTACTGGTTTTGCATTGCATAATAATACAACTCCTGCATTTCAACAGGCTGGCGGGACTGTGGGAAGAAGAAATCAGGTCA[C/T]GAGGAGACGACGCGTCTCTTCGTCGTGTGGTCTGGCATTTTTGCCGCACGCGTCTGCTGCTGTCCATCCTCTGCCTTATGGTTACTCAACTGGCAGGCTTCAGTGGCCCAGTAAGTAACACCATCTCAGCTCTGTGTCGTCTTTCTGGTGTCTTTTCTTCTTCTCCCTCTATCTACCTATCCATCTCTCTCCTACTCTGTCTTTCTCTATCTCTGTGTATTATTAGCATTGTAGATGCACCAATCAAATCCTGCATCCCCTCAGATGCTCAGGTGAGTGTTAAGATGGGGAAAGGAATGTGTTATTGTGTTTATATTGTCACTGGGCATCTGCTTTACCTCTGCGGTGTGTCCAGTGAGGCTCTCCAAACCAGATTATCAGCTTATTTTTTTTAAAGTGCCTTAATTATGTGTGCCAACACCAAAAGAGTATTACAGCTTTTCTGCTCCTTTTCTCTTAATAAAAAAACTGAAACAGGGAAATTTGATCATTTATAAATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43169
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087070 Nonsense 155 1426 4 28
ENSDART00000135045 Nonsense 155 241 5 5
ENSDART00000087070 Nonsense 155 1426 4 28
ENSDART00000135045 Nonsense 155 241 5 5

The following transcripts of ENSDARG00000061233 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 44227542)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 45816597
GRCz11 18 45813423
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCTGCATTTCAACAGGCTGGCGGGACTGTGGGAAGAAGAAATCAGGTCA[C/T]GAGGAGACGACGCGTCTCTTCGTCGTGTGGTCTGGCATTTTTGCCGCACG
Long Flanking Sequence:
CTGCAAGGAGGTTTTTAGAAAGCCTAGTAAGAGCTTGATTAGCTAGCCCAGGTGTGTCTGATTGGGGTTGGAAGTAGACTTTGCAGGACACCGGCCCTCCAGGACCAAGCTTGGACATGCCTGTTATAGGCCATTCATTGATTTATAGACCAATAATAATACTTTAAAATCTATTCTGAATGTAACTGGGAGCCAGTGTGAAGACCTGAGGACAGGTGTGATGTGCTCAGATTGTCTGGTTCTGGTCAGAACCCTGGCAGCAGCGTTCTGGATAAGCTGCAAGTGTCTGACTGTCTTTTTGGGAAGGCCAGTAAAGGAGTCCATTACAGTAATCCACCCTGCTGGTCATAAAAGCATAAACAAGTTTTCAGTGGAAACAAAGCATCTAATTCTTGCTGTGATTTTGAGAAAATAGTATGCTACTGGTTTTGCATTGCATAATAATACAACTCCTGCATTTCAACAGGCTGGCGGGACTGTGGGAAGAAGAAATCAGGTCA[C/T]GAGGAGACGACGCGTCTCTTCGTCGTGTGGTCTGGCATTTTTGCCGCACGCGTCTGCTGCTGTCCATCCTCTGCCTTATGGTTACTCAACTGGCAGGCTTCAGTGGCCCAGTAAGTAACACCATCTCAGCTCTGTGTCGTCTTTCTGGTGTCTTTTCTTCTTCTCCCTCTATCTACCTATCCATCTCTCTCCTACTCTGTCTTTCTCTATCTCTGTGTATTATTAGCATTGTAGATGCACCAATCAAATCCTGCATCCCCTCAGATGCTCAGGTGAGTGTTAAGATGGGGAAAGGAATGTGTTATTGTGTTTATATTGTCACTGGGCATCTGCTTTACCTCTGCGGTGTGTCCAGTGAGGCTCTCCAAACCAGATTATCAGCTTATTTTTTTTAAAGTGCCTTAATTATGTGTGCCAACACCAAAAGAGTATTACAGCTTTTCTGCTCCTTTTCTCTTAATAAAAAAACTGAAACAGGGAAATTTGATCATTTATAAATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43170
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087070 Nonsense 373 1426 7 28
ENSDART00000135045 None None 241 None 5

The following transcripts of ENSDARG00000061233 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 44235682)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 45824513
GRCz11 18 45820625
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAACTACATCAAATTCATTAAGATGTACGCCTGGGTTAAGGCTTTCTCA[C/T]AAGCTGTCAGAAGTAAGTTGCTGTCTTTTGTATTGATTTGAATGCTTTGC
Long Flanking Sequence:
TATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAAATAACAACTTGTATATTATACTAGTTACTAATAAAGTTATGGTAACTAATAATCTTAACTTCAAAACTATTATTTAATTGAAGCTCAACTTTAAAAGCTAATAGTTACTAGTTAATTAGTTAAAGTTCATTCTATACAGATAAAATTGAATAGAAATATTTGCTGTAATGCTATTGTTTTTGTTTGTTGGTGCTGGTAGATGTTTAGCTCCAGGCTGACGGCGTACTTCAGGAGGAAGGGAGTCGCTGTGACTGACCAGCGCGTGCAAAAGATGAACGAGATTTTGAACTACATCAAATTCATTAAGATGTACGCCTGGGTTAAGGCTTTCTCA[C/T]AAGCTGTCAGAAGTAAGTTGCTGTCTTTTGTATTGATTTGAATGCTTTGCTCAGTGTTAGCAAGTGTATCCTTTATTATCTTACTGTCATTTATATAATAATCTGCTCAGACTTTATTTGAATGTACAATTCATGCTATTAACACATCATTAACTAAGATTTTTAGCTCAATAGACTACTATAAAGCTGCTGAGTAATAGTTAGTAAGGTAGTGGCTGGATTTAGGTATTAGAAATGTAAAATAAGATCATACATTATAAGTGCTAATAAACAGTTAATAACTTAATAAGAGGCAGGTAATAAGGATAGCGCTCATTCTCATACTTCAGCCTCCACATCAAAGTTCCTGAAAGTAAACAAGGTCAAGGTTCTCCAGGGCCAGCCCAGTCACCAGAAATGAACATTATTGAGCATGTCTGGGGTAAGATGAAGGAGGCATTGAAGATGAATCCAAAGAATCTTGATGAACTCTGGGAGTCCTGCAAGAACGCTTTCTTCGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2950
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087070 Nonsense 391 1426 8 28
ENSDART00000135045 None None 241 None 5

The following transcripts of ENSDARG00000061233 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 44236825)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 45825656
GRCz11 18 45821768
KASP Assay ID:
554-2562.1 (used for ordering genotyping assays)
KASP Sequence:
CCAACAGGAATAAGAGATGAGGAGCGGCAGATCCTGGAACGAACAGGGTA[T/G]TTTCAGAGCATYACAGTTGGCGTGGCACCTATCGTGGTGGTGATCGCCAG
Long Flanking Sequence:
TTTCTGTGAAGTGACAAGACTTTTGTCTCACTAAAGTCAGACCTTACTGTCCTAATTAAATCATTAGAAATCAAGGCATGATCACATTTTATTTTGGTCAAATAAGCGTCATCTAGAGGCCTTTGCCTTTCATATAAGCCACTTCTGATACCAAGTGATCAACTAGAAGTCAAGTTATTGTTGTTCCTAAAACTTGGGTAGGCGACAAGACTTTGGTCAGGTAGTGAAGAGTTAATACAATTAATTATTAAATAAGTGATAATTATTATGATAAGTGTAAGTATAGCTTGACTAAAATGAAGTGCAAACGAAACATATCTACATAGTTTATTTAAAAATGAAAATACTGAAACAAAATTTTAGTTAACATGTTTTTTTTGTCATTCTTAAAGATGAAAACACTGATTTGGCTTATTTGTATGCTTACATCTGCTAATTACTGCATACTGTCCAACAGGAATAAGAGATGAGGAGCGGCAGATCCTGGAACGAACAGGGTA[T/G]TTTCAGAGCATTACAGTTGGCGTGGCACCTATCGTGGTGGTGATCGCCAGCGTGGCCACATTCTCCACCCACATGTTGCTCGGTTATGACCTCACTGCGGCACAGGTAACGTCACAATGCCTGTTTTGATTTGTGTTATTGTATTCATACTTTGATGATTTACTTAATATTTTTGTTTGTTTGCAGGCATTTACTGTCGTCACTGTTTTCAATGCCATGACGTTTGCGTTGAAGGTCACTCCCTTTTCTGTCAAGTCTCTCTCTGAGGCTTCTGTCGCCATCGACAGATTTAAGGTAAGATTTCTGTCCTGGTTTCAGTTAAAACACAGGCTCATTTTAGATACGTACCCCTGTATACATTTCTGGAGAGCGCGAATTATGTATGTATTACGCTATGGGGTGGTATGACACTGCCGCCGGCTTCTGTTCCTTTTCGGGCTACCAGCTGACCGCTTACCGCCATGTGGACGGCTTTTCCGCTGTTACCAGTTTGTCCAGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32218
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087070 Nonsense 1066 1426 21 28
ENSDART00000135045 None None 241 None 5

The following transcripts of ENSDARG00000061233 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 44255827)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 45844658
GRCz11 18 45840769
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTGAAAAGACCTCCAGTGCTAGATTTTGTCTGTCTTCTGCTGCAGGTA[T/G]CAGGAGTTGCTGGATCAGAATCAGGCTCCTTTCTATCTGTTCAGCTGTGC
Long Flanking Sequence:
TCCAGGAAAATTATACTTAAATGTCTTTTAATGCTTAATTATACCATAATACTAGTCTACATCACATAGCAAAAGCACTGACCCGTCTTGTGTTTCTGATCTCTTCTTGTCTCTCAGTGGACACGCGTCTGCCATTTCAGGCTGAGATGTTCATCCAGAACGTGATTCTGGTGCTCTTCTGCTTGGCTGTGATCGGCAGTGTTTTCCCCTGGTTCCTGGTGGCCGTCGGGCCGCTCGTCCTCCTGTTTACGGTGCTTCATGTGGTTTCTCGGGTCTTCATTCGAGAACTCAAACGATTAGACAACGTCACACAGTCGCCTTTCCTGTCCCACATCGCCTCCAGCATTCAGGGCCTGACCACCGTTCATGCGTACGGGAAAGAGGACGAGTTCCTCCACAGGTAAATGAGGACGGCGGATCATTTTGCCGTGCTCCTTAAATACGATATGTTTTTGAAAAGACCTCCAGTGCTAGATTTTGTCTGTCTTCTGCTGCAGGTA[T/G]CAGGAGTTGCTGGATCAGAATCAGGCTCCTTTCTATCTGTTCAGCTGTGCCATGCGCTGGCTGGCTGTGCGTCTGGATGTGATTAGCGTGGCTCTCATTAGCATCACAGCTTTGATGATTGTCCTCATGCATGGTCAGATTCCTCCTGCGTATGCAGGCTTGGCCATTTCCTATGCTGTACAGGTGAGTGCACCATTTAATAAAAAAAAGTTTTGAGATTTTATTTATTTTATTACCCAGCTTTGAGTGTGCACCATTTGGCATAAAATCAGGAAAGATACTCTTGAAACAGGCTTGCCATATAGTTTCTAAACTAACACAACCTAATTTGGATGAAACCATTTATAACTAATGGTATGTTTACAGATATAAACTCACCGGCCACTTTATTAGGTACACCTGTCCAACTGCTCATTAACTAAAATTTCTAATCAGCCAATCACATGGGAGCAACTCGATGTATTTAGGCATCTAGACAAGGTCAAGACGATCTGCTGCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43171
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087070 Essential Splice Site 1158 1426 23 28
ENSDART00000135045 None None 241 None 5

The following transcripts of ENSDARG00000061233 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 44257720)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 45846551
GRCz11 18 45842655
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTTAGATGGGTTGAGAACAGAGAAGGTGACATTCAGTTTTTTTGTCTCA[G/A]TCTCTGTCTTTGGAGGCTCCAGCGCGGGTGAAGAACAAGGCTCCTCCATC
Long Flanking Sequence:
GTTTGAACTAGATGCTAATGGTCTAATCTGATTCAATAATCTATGCTAAGCTAAGCTAAACGTCCTCCCGCCAGACTCAGAAATCAACTGAATGAATTAAAAAATAGGAAAACTCAACAGTTTACCTATAGGGAGCTTGTCAAATGAGCCTATTTCCAAACAAATGGAGTGTCCTAGTTTGAACTGAAAAATCAAAAGCAGTGTGTAGTACACCTATTTTTCCCAAACCTGGCTAAAAACGGTTGTATTGTCATATAGAAATTGTTTAAAGGATCTAGAATGATAGTTTATGTGATTCGCCCACAGCTGACAGGATTATTCCAGTTTACTGTCCGCTTGGCCTCTGAGACTGAAGCTCGGTTCACCTCAGTGGAGAGAATCCATCATTACATTAAGGTACCCATTCCTGCATTGTTTTTGATAGAAGAGTTTAACTCGACCGACATTTAATCTTAGATGGGTTGAGAACAGAGAAGGTGACATTCAGTTTTTTTGTCTCA[G/A]TCTCTGTCTTTGGAGGCTCCAGCGCGGGTGAAGAACAAGGCTCCTCCATCTGACTGGCCTCAGGAGGGTGAGATTGTGTTCGACCAAACAGAGATGAAGTACAGAGACAACCTGCCGCTGATACTGAAGAAAGTCTCCTTCACCGTTCGACCAAAGGAGAAGATCGGCATTGTGGGAAGAACAGGCTCAGGTCGGTCACTCCTGCTTGTTTCTTTCTTTTCTTAAAGGGATGGTTCACCCCAAAAATTAAAATGGACTCTCCTTCAAGTCATTCCAAACCTGTTTGAGTTTCTTTTCAGTTGAACACAAAATAAGTTACTTTGAAAAATGTTAGAAACCTGTAACCATTGACTTCCATAGTATTAAAAACAAATACTATAGACCTTTTTCTTTGAATGCAAAATTACCCATTATGCTTTGCGTGTATGCGCAAGGAGAATGCGAAGAACTTCCAGTCGGCAGCTGATGCGTGTAAACAGTCACATTTGGACAGCTTCGAA
Associated Phenotype:
Not determined