ZMP

IDH2

Ensembl ID:

ENSDARG00000003795

Description:

isocitrate dehydrogenase 2 (NADP+), mitochondrial [Source:HGNC Symbol;Acc:5383]

Human Orthologue:

IDH2

Human Description:

isocitrate dehydrogenase 2 (NADP+), mitochondrial [Source:HGNC Symbol;Acc:5383]

Mouse Orthologue:

Idh2

Mouse Description:

isocitrate dehydrogenase 2 (NADP+), mitochondrial Gene [Source:MGI Symbol;Acc:MGI:96414]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa43120	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa13876	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa43120

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000004692	Essential Splice Site	37	447	2	16

Genomic Location (Zv9):

Chromosome 18 (position 25893930)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	26123613
GRCz11	18	26108131

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GAATGGAAAAACTGGCTTGTAAGAATAATTAGTTTTTGTTTTATTTGACA[G/A]ATGCCGATAAACGTATCCAGGTGGCACAGCCGGTGGTGGAGATGGATGGA

Long Flanking Sequence:

ATCGTAATGCCATCTCTTTGATCATGTACAGAGCAGTGTTATAAAGGTAGTGCAATGCAGGCGCATGTGAAACGGTGTGTAAGTGTTTGCGAGACCAAAACATCCTCATTTGCTGGCTTGGTGCAGTTAAATGGCCTCCCTGGCAGTTTATTTTTTTCTTTTCATAGTAAATGATACATTATTTCTGTGCATTATTTATGAGCTTAATAGCTGATCCAGTGTCAGCAAGAATGACAGTTCAGTGCTAGTGATGCACAACGTGTTTCTTTAGAAACCAGAAATTGTACCGCCGACTAGTGACCAACCAGTGCAATGACTGCCAACATTTAGTGCCAAAGTCTCTAGTGGTGTGAACAGGGCTTTGTCTCTGTATTATTCTCCTACTTGAGGAACCACTCATTTCCGGGTGTCTCACAAGTGGGGTAAAAACACAATCACTTATTCAGGCTTGAATGGAAAAACTGGCTTGTAAGAATAATTAGTTTTTGTTTTATTTGACA[G/A]ATGCCGATAAACGTATCCAGGTGGCACAGCCGGTGGTGGAGATGGATGGAGATGAGATGACCAGGATCATCTGGGAGTTCATTAAAGAAAAGGTGCTTAAACGGCAAGCGTCTGAGTGAGCGAAAGAATGAGGAGGAGGGAAGCAGTGTCTGTCTGGTCTATTTTTAAATCTGTGATACATACACACAAACAGAGAGAAACAGAACGCAGGAGGGAAAGATGTAGAGGGCAAAGGAAAGAGAAGTGAGTAAGAAGCCTAGACAGACACAGACAGAATGAAAATTGGGTTAGACAAGAGTAGAGAGACAAAAGGAGACGGAAATTGGAAAGGGAATGCGACAGCATCTCTAGGGAGAATTAAAGGGATGAGGAGAGAGTGGAGGAGTGATCGGCGTGTTATACAGATCTCCTTTTTTAAAGCGACGGCATGATAGGCTTACTGGGAGAGTTACGCGTGAAGACTGAGATTATGTTCGCGTCACGCAGGGGGCAGAGCCAGC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa13876

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000004692	Nonsense	37	447	2	16

Genomic Location (Zv9):

Chromosome 18 (position 25893928)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	26123611
GRCz11	18	26108129

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

ATRGAAAAACTGGCTTGTAAGAATAATTAGTTTTTGTWTTATTTGACAGA[T/A]GCCGATAAACGTATCCAGGTGGCACAGCCGGTGGTGGAGATGGATGGAGA

Long Flanking Sequence:

CGTAATGCCATCTCTTTGATCATGTACAGAGCAGTGTTATAAAGGTAGTGCAATGCAGGCGCATGTGAAACGGTGTGTAAGTGTTTGCGAGACCAAAACATCCTCATTTGCTGGCTTGGTGCAGTTAAATGGCCTCCCTGGCAGTTTATTTTTTTCTTTTCATAGTAAATGATACATTATTTCTGTGCATTATTTATGAGCTTAATAGCTGATCCAGTGTCAGCAAGAATGACAGTTCAGTGCTAGTGATGCACAACGTGTTTCTTTAGAAACCAGAAATTGTACCGCCGACTAGTGACCAACCAGTGCAATGACTGCCAACATTTAGTGCCAAAGTCTCTAGTGGTGTGAACAGGGCTTTGTCTCTGTATTATTCTCCTACTTGAGGAACCACTCATTTCCGGGTGTCTCACAAGTGGGGTAAAAACACAATCACTTATTCAGGCTTGAATGGAAAAACTGGCTTGTAAGAATAATTAGTTTTTGTTTTATTTGACAGA[T/A]GCCGATAAACGTATCCAGGTGGCACAGCCGGTGGTGGAGATGGATGGAGATGAGATGACCAGGATCATCTGGGAGTTCATTAAAGAAAAGGTGCTTAAACGGCAAGCGTCTGAGTGAGCGAAAGAATGAGGAGGAGGGAAGCAGTGTCTGTCTGGTCTATTTTTAAATCTGTGATACATACACACAAACAGAGAGAAACAGAACGCAGGAGGGAAAGATGTAGAGGGCAAAGGAAAGAGAAGTGAGTAAGAAGCCTAGACAGACACAGACAGAATGAAAATTGGGTTAGACAAGAGTAGAGAGACAAAAGGAGACGGAAATTGGAAAGGGAATGCGACAGCATCTCTAGGGAGAATTAAAGGGATGAGGAGAGAGTGGAGGAGTGATCGGCGTGTTATACAGATCTCCTTTTTTAAAGCGACGGCATGATAGGCTTACTGGGAGAGTTACGCGTGAAGACTGAGATTATGTTCGCGTCACGCAGGGGGCAGAGCCAGCAT

Associated Phenotype:

Not determined