ZMP

LOC100000060

Ensembl ID:

ENSDARG00000088817

Human Orthologue:

WDR59

Human Description:

WD repeat domain 59 [Source:HGNC Symbol;Acc:25706]

Mouse Orthologue:

Wdr59

Mouse Description:

WD repeat domain 59 Gene [Source:MGI Symbol;Acc:MGI:2442115]

Alleles

There are 5 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa43028	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa43029	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa43028

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000122009	Essential Splice Site	109	965	4	26

Genomic Location (Zv9):

Chromosome 18 (position 4515256)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	5264927
GRCz11	18	5879680

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GGATCTGGTAAATCACATACGTCTTTGCAAGGCCACACACGTGTAATAAG[G/A]TAACACATGAATTCAAGCTGAAATTACTATGAATTTGGAGGAGCTTGTTT

Long Flanking Sequence:

GTACATTTTCATCCACGACACCTTTTCATCCTCGGGTAAAATGCCAGTTATGTTACCTCGATCTGTTCCAGGACATCGCAATTTACAAATTAAGCCTTCTCATACCAATAAATAAATGTATATTTCATTTATTTAAATAATTTATTTATTGTGTTTATTAGATTTTTCTCAACAACTTTGCACAACATCATACCAAAATACCAAGAAAAATACAAATAAACAAGCAAAACAACAAGCGTGGAAGAGCAGGCTTAAATTAATGCATAGGAGAAGATGTAATCAATAGAAATCACAGAATTACAATTATGTCAACATTTATTTTTTCTTGGCAAGGTTTTGTTCTCTGTTCATTTATTATTATGTTTTACATGAACTTTTTAGGTTGTAAATAATGCCTTTCTCATTTTCATCCAGAGTAACCAGCGTGTCGACTTGTACACATGGCGGGATGGATCTGGTAAATCACATACGTCTTTGCAAGGCCACACACGTGTAATAAG[G/A]TAACACATGAATTCAAGCTGAAATTACTATGAATTTGGAGGAGCTTGTTTTAAAGTCAATATGAATTGAAATTGTTTGTGAAATATTGCAGTATTTATTATGAAGGCATAGGTTTGATCTTGACTTTGCTGGCGACCTATGAACCCCCATCTGCCACCATCCTCATTTGCGTGTCATCCAACTTACACACCTTATTCTTGCATAGGAAAATTCCCCTGCTCAGCCTCTCATATGACAGCGGGAAAAGGCTCAGCCAATCACAATGTTCATTTGTGGTTTGTGGGGGCGGTATGACTCTAGTGGAGAATCAATCAATCTGTCAATCACGTGTTCCACCAATGCCAAATCATATCCGTCCAATCAGTTCCATATGGACAAAATCAAGCCCCGCCTACTTCGGTTATTGATTCCGAAAAAAATATTTCGAAAGGATTTTTACTAAGATGCACAGTTGAAGTCAGAAGGCCTCCTGAATTATTAGCCCACTTTATATTTTTTCC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa43029

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000122009	Nonsense	904	965	26	26

Genomic Location (Zv9):

Chromosome 18 (position 4609690)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	5295058
GRCz11	18	5909428

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CAGAGTTTGGCGTTTACTGCTGTCACTGTCGCAGTCAGGCTCGCGGCACA[C/T]AGTGCGCCGTCTGCAAGCGCTTCACCTTCCAGTGCTCCATCTGCCATGTG

Long Flanking Sequence:

AACTAATAAAGTTATGGTAAATAATAACCTTAACCTTCCGAATTCGATATTAATGCAATACAAATACAAAACCTTTTAAAAACTAGCCAACGTGAGCTAACAAAATCAATATGGTTCGTTTCGATTTCATTTGTACTTCAAGGGGCACAACATTAGTCTAGAATAGGAGTCACCAATCTCGTTCCTGGAGGTCCGGTGCCCTGCAGGGTTCGGCTCCAACTTGCCTCAACACACCTGCCTGGGTGTTTCAAGTATAACTAGCAAGACCTTGATTAGCTGGTTCAGGTGTGTTTGATTAGGGTTGGAGCTAAAATCTGCAGGACACCGGCCCTCCAGGAACAAGTTTGGTGATCCCTGGTCTAAAATCAGTAATATCTGCAGTGTGGGTGAATGTTAAACTCTTCGACAAATGTTTAACACTGCATTTGTGACTGGGGTCTCTTTGCTGTGCAGAGTTTGGCGTTTACTGCTGTCACTGTCGCAGTCAGGCTCGCGGCACA[C/T]AGTGCGCCGTCTGCAAGCGCTTCACCTTCCAGTGCTCCATCTGCCATGTGGCCGTCCGCGGCTCCTCCAACTTCTGCCTGAGCTGCGGCCACGGTGGACACACCAGCCACATGATGGACTGGTTCCGCTCACAAGACGTCTGTCCCACCGGCTGCGGCTGCCACTGCCTCCAGCAGAGCACTTTCTGAACAACACGAACAAGTAAGACTAGGCCTCAAAACCCAAAAACTGTACTGTAGCTGCTTCTGGATCAGATATGATCCAAGAGCTGTAAATATTAACCTTATTATAGGTCTAACCAGCCTAGTTAAAAGGGATAGTTGACCCAGAAATGAAACCTGTCATCATTTACTTGCAAACCATTTTTTTGGTTTATTAGAAAAGAAGATATTTTGAAGAATGCTGGAAGCCTGTAACCATTCACTTCCATAGTATTTGTTTAAAAACAAAACAACCACTGACTTCTATAGTGTTTGTTGTTCCTGTTATGGATGCTAATA

Associated Phenotype:

Not determined