Busch Lab

ZMP

myo6b

Ensembl ID:
ENSDARG00000042141
ZFIN ID:
ZDB-GENE-030318-3
Description:
myosin-VI [Source:RefSeq peptide;Acc:NP_001004110]
Human Orthologue:
MYO6
Human Description:
myosin VI [Source:HGNC Symbol;Acc:7605]
Mouse Orthologue:
Myo6
Mouse Description:
myosin VI Gene [Source:MGI Symbol;Acc:MGI:104785]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa2929 Essential Splice Site F2 line generated Not yet available
sa42976 Nonsense Mutation detected in F1 DNA Not yet available
sa18082 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa2929
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000042203 Essential Splice Site 185 1255 7 32
ENSDART00000061762 Essential Splice Site 185 1267 6 33
ENSDART00000088801 Essential Splice Site 185 1267 7 34
ENSDART00000131566 Essential Splice Site 185 1255 7 33
Genomic Location (Zv9):
Chromosome 17 (position 36969364)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 36854261
GRCz11 17 36801846
KASP Assay ID:
554-3365.1 (used for ordering genotyping assays)
KASP Sequence:
ACCACATCTTACGGCACAGGCCAAGATATAGATGAGAGGATTGTTGAAGG[T/C]AAGTGTCTAGCACAGTACTGCATGYTCTTTTTTTGCATMTGATGCAAAAT
Long Flanking Sequence:
TTGTTAAGCACTAGTCTTTTAGCCACCACCATGCTTTGCATCAATGACTCTTGCATTGCCTGAAGTAGAGCAGATGTAATTTGTGAGACGCCAAAGATGGCACGGCATCTGGTGGAAAAGGTCTGCTGTAAGCTTTGGAGCACCAGTCAGTAGAAAACATTTTAAACAATGTTACATTAAACGATAAAAAATAGAATTACAATGTTGTTTAAAATTAAAAGTATTACTATATTTACTGTATATTGATCAAATAAATACTTTATTACTTAAAATACCTTGGTTAATTGAAATACGGTTTGTATAAAATATGATCAAAAACATTTTATAGTCCTCAATAATGTTACTGTTTTGCAAATTAGTTTGGGGGTTGTTTTGGGCCAGTTTGATTATTAATGTAATCATGTTTTAATACTGTAAGTGTTTTTTTTTTATTATTATTTCAGGTATTTAACCACATCTTACGGCACAGGCCAAGATATAGATGAGAGGATTGTTGAAGG[T/C]AAGTGTCTAGCACAGTACTGCATGTTCTTTTTTTGCATCTGATGCAAAATGTTTGTTTTTACAGTACATACTGTATATTTCTCTGCTGTGTTCAGCCAACCCCTTGCTTGAAGCTTTTGGAAATGCAAAGACGGTCAGGAACAACAACAGCAGCCGCTTTGGAAAGTTTGTGGAAATTCATTTTAATGAGAAGGTGAATTTAGTTTTATAGTCTAAAGACAAGAGTGTGAGTGTACAAGATTTCACGTAGGTATTATTAACTATGTGTGTTGTGTCTTGTGAACCGTGTCCAGAATGCAGTTGTGGGCGGTTTTGTCTCTCACTATCTGCTGGAGAAGTCTCGGATTTGCATGCAGAGTCAAGAAGAGCGAAACTATCATATATTTTATAGACTGTGCGCAGGGGCGTCAGAGGACATCAGGAACATGCTCCATCTCAACTCCCCCGACAGCTTCCGGGTCAGTTTCCTGTACATTGTGTGTCAGGAAAACCTGGAAATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42976
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000042203 Nonsense 1058 1255 29 32
ENSDART00000061762 Nonsense 1070 1267 30 33
ENSDART00000088801 Nonsense 1070 1267 31 34
ENSDART00000131566 Nonsense 1058 1255 30 33
Genomic Location (Zv9):
Chromosome 17 (position 36870252)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 36755149
GRCz11 17 36702734
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGTGCAGGCCAACAAGGTGGCAGCTGGGGTGAAGAAGTACGACCTGAGC[A/T]AGTGGAAGTACGCTGAGCTGCGAGACGCCATCAACACCTCCTGTGGTAAG
Long Flanking Sequence:
GCTGTGCCCATTGCCCCAAAGGCTTCAGTAAAAATACATTCCCTCCTCAGACTGGTTTACTGTGGGAGCCTGGGCTTAATGTGATCCCTGTGAAACCCTTACAGAGCTCACATGTGTGCCTCCCTATCGCTTAGCATTAACCATCGTTAACCGCCATTAACCACCCTCAGCGCTGCAACCTCAGTGTTGCCAAGGCTGCATCTAATTTGCTCAGTGAGGTGTTAATTTGGCATGATCCGTGCTATTTCCATGTCATTACAAGTTTCAGAGAGAATGTATCTCTACGTAAGCAGAAGGCCAATTAATTGTCTGATTGTGCTGTGGCCTAGGGAACGTTTAGCAGCTGGTAACGGGAGCTTAATAGATGCATCAGGGCCTTTGCCTGTGGAGAAATATGAAGCTAAGAAAAAGTCCAAATTGTTCTTCCACTCTGTAATCTCAGGGGTGCGCAGGTGCAGGCCAACAAGGTGGCAGCTGGGGTGAAGAAGTACGACCTGAGC[A/T]AGTGGAAGTACGCTGAGCTGCGAGACGCCATCAACACCTCCTGTGGTAAGAGCAATCAGTCTTCTCAATCTGATCCCAGAACTTCCTGCTGACCTCAAGCCGCTCTTGGCAAAAAAAAAAAAAAAAAAGCATGTCATTTTGGAGATGGGGGGCTAACATGCGTTATGTGGAAGATGGGGGAAATACAGTTTTTTTTTTAGAGGGACTGGTTTTAAAGCCTACTCTCAGTCCATTATTATTTTAAAAGTGAATTAATGATGTATTCTTCCTTTTTATTTGCAAGTCTCTTTGTTTATTTGTCTTATTTTCTGCTAATTGAGACTTCACTCACTTTTTTTTGCTTCGCCGACTTTCTGGGCTGTCATGTTGGTTTCATTTTTAGGTGTTTAGACTCAAAGGAATAGTTCATGCTAAATTAAGTCATAATTTAGTTGCTTTTGTGTTGTTTCAAATGTGGTTTTCCTTCTGAAGTATACAAAATCTGATGCTCAGGCTGTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18082
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000042203 Nonsense 1137 1255 31 32
ENSDART00000061762 Nonsense 1149 1267 32 33
ENSDART00000088801 Nonsense 1149 1267 33 34
ENSDART00000131566 Nonsense 1137 1255 32 33
Genomic Location (Zv9):
Chromosome 17 (position 36856295)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 36741192
GRCz11 17 36688777
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACCCTGCTCCACCTGTCCCAGCCCGGCAACAAGAGATCGCGATGAAYCGA[C/T]AGCAGCGTTACTTCCGCATTCCCTTCATCCGSCCCGCAGACCAGTACAAA
Long Flanking Sequence:
ATTTTGTTTCACCTTTTGACTTGCATTAATTGCTTAGTTGCATCACTCTAGTTTTTGTCTTCATGCTCTGATTCGCTCTCTGAAACATCTAGAACAAAGTTAGGTGCCCAAACTCGGTCCTGGAAGGCCAGTGTCCTGCAAAGTTTAGTTCAAAGCCCAATCAGACACACCTGGGCTAGCTTATCGAGCTCTTAGTAGACTTTCTAGAAACATCCTTGCAGGTGTGTTGGGGCAAGATGGAGCTAAAATCTGCAGGACACCGGCCCTCTAGAACTGAGTTTGGACTCCCCTGACCTAGAACAACACATTTTGTAACAACATGCTATAAATGACATCTTCATCACAATCAGATTACCCTAGAATCTCAGCAGCAGGTTTTGAACAGACAAGCAGACACAATTTTTTTATATTTTTTTTAAATTTTATATATTTGTATTCCAGCCCAGCAAAACCCTGCTCCACCTGTCCCAGCCCGGCAACAAGAGATCGCGATGAACCGA[C/T]AGCAGCGTTACTTCCGCATTCCCTTCATCCGGCCCGCAGACCAGTACAAAGACCCCCAGAACAAGAAGAAAGGCTGGTGGTACGCTCACTTTGATGGACCCTGGATCGCTAGGCAGATGGAGCTTCATCCAGACAAGCAGCCGATCCTCTTGGTTGCAGGTACCAAATACTATGAAGTTAAATCAGTCATTTTCTCCAATCTATAAACAATTAATACGCCAGAAAAGAAGCTGGAATTGATAAAATAGCTGAAACTCTTAAAGGCGGTTAAATTAGGTATTGCACTCCTGGTTCAAAACACACGCAAGCACAGGTTGCTAGATTGGAGACAGAAGCGACTATCAAGCCTAAAGACTGATTTAGATTGTGTTCTAAATAAAAGCAATAACACATGATAGAGGAAATATTTACCATATTGAAAGGAGTTTTTGTCCTAACCAACACCTCGAATTGATATTTTAGAAAAAGCTTTTATTTCTCGCAGCTGAATAACAGGATAA
Associated Phenotype:
Not determined