ZMP
gsk3a
Ensembl ID:
ZFIN ID:
Description:
glycogen synthase kinase 3 alpha [Source:RefSeq peptide;Acc:NP_571465]
Human Orthologue:
GSK3A
Human Description:
glycogen synthase kinase 3 alpha [Source:HGNC Symbol;Acc:4616]
Mouse Orthologue:
Gsk3a
Mouse Description:
glycogen synthase kinase 3 alpha Gene [Source:MGI Symbol;Acc:MGI:2152453]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa42670 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa22769 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa42670
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000024935 | Nonsense | 36 | 440 | 1 | 10 |
| ENSDART00000111481 | Nonsense | 36 | 440 | 1 | 11 |
| ENSDART00000138335 | None | None | 40 | None | 4 |
The following transcripts of ENSDARG00000015681 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 16 (position 12946537)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 11351780 |
| GRCz11 | 16 | 11242682 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGGAGCCGCTGCAGCCGCCGCCGGATCAGCCGTCGCCGGTGGAAGCTCAT[C/A]AGGAAAGACGGGGGGCGCGCAGGCCTCAGGCGGGAGTTCGTCTGGTTTCG
Long Flanking Sequence:
CTGCTATCATCTCTGACTCACATTTGGGTGTAAATGTCAAATAAGATATTGAAAACCCCTTGTTTAATTGAACTTTTCGCACAATGCTATTGCAGAATATTGTAGGTTCTTGTCATGAAAAATTGAAAACCTGGACTTTCTTATGCTGCAGGATCTGTGCACGTGAGGGCATTGTTGAACTTCATTGCCCAGAAGACAATGCGCACAGAGCGTCACTGTGCGTCAGCTCCAGTTGCCCAGCCACAGAAGAAAGAGGAGGCGCAGAATCCTAACGAGACTTCAGCTATCTTTATTTTTTTAACGATTATTGTTGTTTAAATTGACATATCTACCACGCGCCTGGGCCAGTCTACCGGCACACTTTACCCCCGCTCTGGCACATTTGCAACCCGAAATGAGCGGCAGCGGGCGGCCCAGGACTAGCTCGTTTGCTGAGCCTCCGGGGGTTCCGGGAGCCGCTGCAGCCGCCGCCGGATCAGCCGTCGCCGGTGGAAGCTCAT[C/A]AGGAAAGACGGGGGGCGCGCAGGCCTCAGGCGGGAGTTCGTCTGGTTTCGGAAACCTAAAGCTGGGCAGTGAGTATCATTCAATGACATCACACGACAATCCCAGTAAATGTGATATTAGGAAACTAATACGACCCCAAATGCTGGATCGGGCTGCGTGCTATTCATTAATTTGCCTGGTTATTTTGCCACGATCGCGTTAACCTACTTTAGGCGGCTAACTGGCTAAGCTAACGTGAGCTTGTTTTTGTAGACGGATCAAGGGCTTTGATTGCGCTAACTACACTAGCTCGACAATCCTTCACCAGAGCAAGAACTAAACACATCTGCAATAAACGATACAAGTGCATAATATTTTCCCTCAATTTGAGCCCTGCTTTAAATGGAATCCGGGGTTTATTGGATGTTCAGACGTCGGCTGTATTCCTCAAGCTGTGCTCGTTGGGTAACAAAGCTCACTTAGCCCAGCCGGCATCATCTAACTCATTGTATCATTTAGTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa22769
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000024935 | Essential Splice Site | 419 | 440 | None | 10 |
| ENSDART00000111481 | Essential Splice Site | 419 | 440 | None | 11 |
| ENSDART00000138335 | Essential Splice Site | None | 40 | None | 4 |
The following transcripts of ENSDARG00000015681 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 16 (position 12987098)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 11392341 |
| GRCz11 | 16 | 11283243 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTCTCATTCCTCCACATGCTCGCTCGCAGACGACACCTGCCTCGCACGG[T/C]ACTGATCACACTTACAAACACAGTGCCTTTGATTTACCCTTCATGTCAGT
Long Flanking Sequence:
CTCGTGTTCGTTTCATACAGATTACGAAAGCAAAAAACTTTTGTTTTCAAGTAGAGTTGCTTCATTAAAAGATGCAAATTTCAAGCTTTATGTGGAGATATTTCTTATGTCTGTGAAGCAAGTATTTGCTGAGATTCCAGTGTGTGTTGATTACAAAAAAACTGTCAAATAAGCACACATCTGGTTAGAGCTTCTCCCCCATAGGAAACGTCAGTCTATAGCGATCGATGATCGGCTCCTGTACTAGTAGGCGGGGCTTCATTCGCCATATTGAACGTTACACTTTTTCCCCCATTCGAAACAATACGAGTGACATGTCTGGTGTATTCTATAGCGTGCTCAAATACAAAGGAATCTTGTTTTTGGCATGTAGCCTACTCACGTTGATGTCTAATCTCTGTCTTTCTCTCTCCTCCTACAGAGCTGTCTATCCAACCACAGTTGAACTCCATTCTCATTCCTCCACATGCTCGCTCGCAGACGACACCTGCCTCGCACGG[T/C]ACTGATCACACTTACAAACACAGTGCCTTTGATTTACCCTTCATGTCAGTCTGTGTGGATTTGTGAATGCACGTGCCCTGAAGTATACTTCGGTTTTTATTTTTATGCTACAGTATACTGTACGATGCTGCAGATAGACAATGATAAAGTGTGTCAGTGTTGGTCAGAGATATTGGCAGTAGCTGATTTCTTTGACGATTTCAAGGTTTTTTAAAAAAACAGATAGAAAACACCCTTGCCATTTTTGCTTGAACAGATTGGAATTAGACTTCATTGGAAACTGTAAAGAGTTTACGTTCATTTGTGTGCCTGCAATAAACCCATCATGCATTTGTAAATAAAGAAAACATACAGGATAATGATTTGTCATCTCGGTTTGTTTGAGTCAGGGGCGGACTGGGACTAAAAATCAGCCCTGGCACTGTAGCCACATCAGCCCACATTATCACACCGACACAGCCCCACCCTCGGACACGCACATTCACTACTTTTATTGGTGT
Associated Phenotype:
Not determined