ZMP
irx1a
Ensembl ID:
ZFIN IDs:
Description:
iroquois-class homeodomain protein IRX-1 isoform 1 [Source:RefSeq peptide;Acc:NP_997067]
Human Orthologue:
IRX1
Human Description:
iroquois homeobox 1 [Source:HGNC Symbol;Acc:14358]
Mouse Orthologue:
Irx1
Mouse Description:
Iroquois related homeobox 1 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1197515]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa24999 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa15451 | Essential Splice Site, Missense | Available for shipment | Available now |
| sa45558 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa42638 | Missense, Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa24999
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006726 | Nonsense | 8 | 426 | 1 | 4 |
| ENSDART00000044190 | Nonsense | 8 | 419 | 1 | 3 |
| ENSDART00000082371 | Nonsense | 8 | 148 | 1 | 6 |
Genomic Location (Zv9):
Chromosome 16 (position 820834)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 737855 |
| GRCz11 | 16 | 813803 |
KASP Assay ID:
554-7583.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTTTGGCTTCCGACGTGGCGGAGGAGATGTCTTTCCCCCAGCTGGGCTA[C/A]CCGCAGTATTTAAGTGCCTCCCAGGCGGTGTACGGAGGCGACCGACCGGG
Long Flanking Sequence:
GCTTTAATTCTCCCGTGTTTATAAGAATTACGAGCCATTCAAATAAGTTCCGCGTGCCTATCAGTTCATTTCCCCAGTGCTGGGCAGCTGTAAAATCGCGTAGACAGGTTGTCACACTACAGTGAATGGATTCTAATGCTAAACATTTAACATACAATCCTCCAAACAGTGCAAAAGTGGCCCTGGCCAATGCACTAACCACATGCGCCAACGAGGAGGAGCCTGGGACGCCAATCAAAGCATCAACTTCAAATTGTATCTGAGAGATCAGCCCAGGACCTAGGGGCAGAGACATCAGTTGGAGCTCAATTGTTGATCTGATCACATCCGACGGACTTGCTGCAGAAGAGAAGCTGAGATTTAAAGACGAGCGCTTTCCCGTTCGCTTTTCAGAGAGAGAGAGAAACTCTTGCACTTCTCGCTTTGGTGGGTTATTTGCTTTTTTGCCTGGTTTTGGCTTCCGACGTGGCGGAGGAGATGTCTTTCCCCCAGCTGGGCTA[C/A]CCGCAGTATTTAAGTGCCTCCCAGGCGGTGTACGGAGGCGACCGACCGGGAGTTCTGACTCCGTCGTCCCGCGCAGGGAGCGCTGAGATCGGGGGTAGCGCGTCTGCGGCCGCCGCTGCGGTGTCCTCGGTGTTGGGCATGTACCCGTACGCACACAACTACAGCGCCTTTCTGCCTTACACCAGCGCCGATCTGGCTCTTTTCTCCCAAATGGTAAGTCCATTTCTAGATTAACTTGTTCTTGCATTTTTCCGCTACTTTTCATAGTTTTTTTATTCCACAATCGTATGCCCTCCATTTATTTGTGATCGTCGCAGGTCAACATAGCTTGCATGGGAAATTGGGAATTGTATTATTACGTTTATAGTACAAATTCTGAAATGGCATTACGGATTTAATGTGATAAACAAGCTAAGAAATGTGTACAGTTTTTTCCGATCGCGATTTCAGCATTGTGTGTGAAAAGTTTTATTTCGACTTGATTTTGGAGTTGGAGGATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa15451
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site, Missense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006726 | Missense | 406 | 426 | 3 | 4 |
| ENSDART00000044190 | None | None | 419 | None | 3 |
| ENSDART00000082371 | Essential Splice Site | 119 | 148 | 3 | 6 |
Genomic Location (Zv9):
Chromosome 16 (position 823481)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 740502 |
| GRCz11 | 16 | 816450 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGAAATGAATCRCCAACGCAACCTTTAAAGTCGTCGTTTCGTCCTCTTCA[T/A]GACAGGTAAATGTGCAYTATWCTCTCAGTTTTCCCTCCTCCTTCTTCATA
Long Flanking Sequence:
AGTCCCGATAGCGCGCAGAAACCTACGTCACCTTCCGTTCCCGTCAGCCACCCGGCCTTCCTGCCCAGCCACGGACTGTACACGTGCCAGATCGGCAAGTTCCACAACTGGACGAACGGCGCGTTTCTGGGACAAAACTCTCTGCTAAATGTGCGCTCTTTCCTGGGCGTCAACCAGCACAACCACCCGGCGCAGCAGCAGCAGCAGCAGACGGGGCCCGCGTCCCTGCAGGTGCTGTCGGCCGGGAACACGGACAAGATGCCGGAGGACCTGAGTCCAAAACACATAGGTAACACACCAGGGCTTTATTATTATTGTTATTAATAGTGATAAAATTATAAATAATATAGCAACACATTAAAATGAAAATGCACGATAAATGTTGCAAACTCCACTCAATCTAATTCCAGTGTTCTCCTATTTTAAATGTCAGATCGGGAAAATGTCCTCAGAAATGAATCACCAACGCAACCTTTAAAGTCGTCGTTTCGTCCTCTTCA[T/A]GACAGGTAAATGTGCATTATACTCTCAGTTTTCCCTCCTCCTTCTTCATATTTTGTTATTTTTTATTAGTAGCAGTAAGCTATCATTATACAAGATGAAGTGGCTGTTTTTAAAACTGCTTATCGGAGGAAGACTCTTGGGATAAAGCTATTTCCTCACAGACAGACAGAGAAAAATCCGCGCTTAGCGCTTATAATAAATAGTTGCGCTTTTCCTGGTGACAAAAGGCCACGAATTCCCCTCCCCGCACACTCAGCGGCTCTCAGGAGAATAACTACTTATCAAGTCACCGAGGCTGTGTGCCTTTCCTAAAGACCCCTGGGAACGGTGGAGCTCGGGGGAGCAGTCCTGCGCAAACTTTCCCCTTTTAAGTGCCTCGATTCCTGCAGGCCCGCTGCGCTGTTCTGGTGACCTGACTTGTGGCTATTATTCATTTGCTGGTGCTTAAGAGTCGCGCAAGTGGATTTAGTGCACAATCGCGAGATTATATTATTTTAAAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa45558
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006726 | None | None | 426 | None | 4 |
| ENSDART00000044190 | None | None | 419 | None | 3 |
| ENSDART00000082371 | Essential Splice Site | 121 | 148 | 4 | 6 |
Genomic Location (Zv9):
Chromosome 16 (position 823550)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 740571 |
| GRCz11 | 16 | 816519 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATACTCTCAGTTTTCCCTCCTCCTTCTTCATATTTTGTTATTTTTTATTA[G/A]TAGCAGTAAGCTATCATTATACAAGATGAAGTGGCTGTTTTTAAAACTGC
Long Flanking Sequence:
CACGGACTGTACACGTGCCAGATCGGCAAGTTCCACAACTGGACGAACGGCGCGTTTCTGGGACAAAACTCTCTGCTAAATGTGCGCTCTTTCCTGGGCGTCAACCAGCACAACCACCCGGCGCAGCAGCAGCAGCAGCAGACGGGGCCCGCGTCCCTGCAGGTGCTGTCGGCCGGGAACACGGACAAGATGCCGGAGGACCTGAGTCCAAAACACATAGGTAACACACCAGGGCTTTATTATTATTGTTATTAATAGTGATAAAATTATAAATAATATAGCAACACATTAAAATGAAAATGCACGATAAATGTTGCAAACTCCACTCAATCTAATTCCAGTGTTCTCCTATTTTAAATGTCAGATCGGGAAAATGTCCTCAGAAATGAATCACCAACGCAACCTTTAAAGTCGTCGTTTCGTCCTCTTCATGACAGGTAAATGTGCATTATACTCTCAGTTTTCCCTCCTCCTTCTTCATATTTTGTTATTTTTTATTA[G/A]TAGCAGTAAGCTATCATTATACAAGATGAAGTGGCTGTTTTTAAAACTGCTTATCGGAGGAAGACTCTTGGGATAAAGCTATTTCCTCACAGACAGACAGAGAAAAATCCGCGCTTAGCGCTTATAATAAATAGTTGCGCTTTTCCTGGTGACAAAAGGCCACGAATTCCCCTCCCCGCACACTCAGCGGCTCTCAGGAGAATAACTACTTATCAAGTCACCGAGGCTGTGTGCCTTTCCTAAAGACCCCTGGGAACGGTGGAGCTCGGGGGAGCAGTCCTGCGCAAACTTTCCCCTTTTAAGTGCCTCGATTCCTGCAGGCCCGCTGCGCTGTTCTGGTGACCTGACTTGTGGCTATTATTCATTTGCTGGTGCTTAAGAGTCGCGCAAGTGGATTTAGTGCACAATCGCGAGATTATATTATTTTAAACGCCTGCATTTCAGTGCAAAACTCTTCCTGAAATGTTTTAATATTACACTCTATAAGAAATGATGCATTG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa42638
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Missense, Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006726 | Missense | 417 | 426 | 4 | 4 |
| ENSDART00000044190 | Nonsense | 393 | 419 | 3 | 3 |
| ENSDART00000082371 | None | None | 148 | None | 6 |
Genomic Location (Zv9):
Chromosome 16 (position 824488)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 741509 |
| GRCz11 | 16 | 817457 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGCATCTCTTTTTCTCTCCACAGTCCCAGAAACCAGCAGGAATCAACAC[A/T]GAGGGTCCTCACAGCGCTGTCCTCCGCTTGATCAACACATTTGCACCCCC
Long Flanking Sequence:
ATTTCAGTGCAAAACTCTTCCTGAAATGTTTTAATATTACACTCTATAAGAAATGATGCATTGTTGTTGTACAGCATTAGATTTAATATGCACGAACCCTAGCATTGCGTTTAAACGTGTCGTTTAAATTAACTAGAATAAAACCCATCGATGAAATACGAATATTTATATATTAATTTATATGTGAATAATGTAACGCACGGCGATCCAATTAAAAAATCCAGCTGAACTGTGATCACTAGCTAGAACACATATAAATGATTATTAGTGCATGCACACTAAAAATGCATGCTGTTTTAACCCAGATATGGACAAACCCAACTGTGGTGTTAAAATTTAATCGTAAAATCACCCCAACATTGGGACTGATCCCTATCAGAGTCACTTATTTAGAGTGTGTGCATGTTAAATGGAAATCCTCGTAGTTTAAAGACTCTCAGCAGATGTTTTGAGCATCTCTTTTTCTCTCCACAGTCCCAGAAACCAGCAGGAATCAACAC[A/T]GAGGGTCCTCACAGCGCTGTCCTCCGCTTGATCAACACATTTGCACCCCCAAAAGGACTGATGGCACTAATAATGGACACTGAAAGCGAAATCAATTCAGCGTAGCGTTGAGTCTCTCTAAAACAACCGGCCGCTGGAGTTGTACATAATGACACCTGTGATCCCTCCCTTACCGTGGGACATTGGTAGGCGTACTTTGTCTTTATGTGTTGGTGTTTTCCTTTAAGGTGACCCACCATTTGTAAATAGCGAGTTGACGGAGTTTGTCCAGATCATATATTTTGTCTAATAAACTAAATGAAATTATAGACACATTCATTCAGAGCTCTCTTTTTGTGGTTTGGATCGTTTGTAAAGAGGAAAACTTTTTTTATTTGGTTTTTATAATTATTTTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTCTCAAAACAGATATGAACAAACCAACATTTGAGTTGAAAAATGTCATTTAAA
Associated Phenotype:
Not determined