ZMP

zgc:110333

Ensembl ID:

ENSDARG00000040628

ZFIN ID:

ZDB-GENE-050417-331

Description:

claudin 8-like [Source:RefSeq peptide;Acc:NP_001017799]

Human Orthologues:

CLDN17, CLDN8

Human Descriptions:

claudin 17 [Source:HGNC Symbol;Acc:2038]
claudin 8 [Source:HGNC Symbol;Acc:2050]

Mouse Orthologues:

Cldn17, Cldn8

Mouse Descriptions:

claudin 17 Gene [Source:MGI Symbol;Acc:MGI:2652030]
claudin 8 Gene [Source:MGI Symbol;Acc:MGI:1859286]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa42618	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa42619	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa42618

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000059484	Essential Splice Site	None	301	3	4

The following genes are also affected by this mutation:

ENSDARG00000092338

Genomic Location (Zv9):

Chromosome 15 (position 41092926)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	42608182
GRCz11	15	42564524

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CCAATTCTCAGTTTGTACTTTACAGCCATGTGATTTGGATCAAAATGAGG[G/A]TGAGTAAATAACCAGTTGTTAATAATAATAATAATAATGTTAATAATAAT

Long Flanking Sequence:

TAAGTTTCCTTCGACAACCATTAAATGTTTATGCGTTTTGTAACAGTGAACTGCTCTGTAAGACAGTAAGCTCCAATGAATGTCTCCAATAAAAGTATATAATTCATATCTAAAAATGATCAATCATAATAAATAACAAAACATTTTCTAGACAAGCAATAAATATTGTCTTGTTTTTAGAAATAATAAGTCAAAATGAAGTGTGTTTTCCTTTAAAATAAGTCAAATAATCTGCCAATGGGGTGAGCAAGATAACCTAATGTTTGATTTGAAGTAAGATTGTTTGGCTTTTTGTTTAAATGTACAAAATGACTTCATGGAATATGATTTAATTACTTAATATTGTAATGATTTTAGGCAAATATTGTATTTTTTTTAACTCAATTTAAGTTTTTTGTTAATTTATGTATGCGTTCATTTCCTTTGCAGATGTTTGAAACTGAAAGAAGACCAATTCTCAGTTTGTACTTTACAGCCATGTGATTTGGATCAAAATGAGG[G/A]TGAGTAAATAACCAGTTGTTAATAATAATAATAATAATGTTAATAATAATAATAATAATAATAATAATAATAATAATAGAGTAGATACCCCTCTTAAAATTGAAGTTTCTTTTGCTATTTTAATTATGTTTTATACTATTTTAATATTGTACTTTGTAATATTTTAATCTGAATAATGTTTTTAAATTACATGATGAATTAATTTATTATTATTCAGGTTGCATTGTACCTCTTTAATTTTTAATGCAGTATATTGTTTCTTAAAAATGTGAACAATACGTTTTATTACATGGTATTTAATATGCATTATACAGAGATAACCTTAAAAGAAAATACCATCCAAACATGTCAGTAAGTTTCCTTCGACAACCATTAGATATTTATGCTTTTTGTAACTGTGAACTGCTCTGTAAGACAGTAAGCTCCAATGAATGTCTCCAATAAATGTTTCTGATTCATATCTAAAATTGATCAATCATAATAAATAACAAAACAATTTC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa42619

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000059484	Nonsense	211	301	4	4

Genomic Location (Zv9):

Chromosome 15 (position 41102944)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	42618200
GRCz11	15	42574542

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CTGCTCATGTGATCATACAAGACTTCTACAACCCTTTGCTTATCGATGCA[C/T]AGCGTAGAGAGCTTGGCGAGGCTTTATATGTCGGATGGGTCACTTCTGCT

Long Flanking Sequence:

ATGAGCAGCTCAAGAAGGAGAAAAGAAAGAGGCGGGATTCGATGTGCTGCGAAGTTGTCGCGCTCATCATCGGGTTTGTCGGATTGATCGGAGTCGCAGCCGTCACCGGTCTCCCCATGTGGAAAGTGACCGCTTTCATCCAGGAGAACATCATCGTGATGGAGACCCGCTGGGAGGGTTTATGGATGAACTGCTACAGGCAAGCCAACATCCGAATGCAATGCAAAGTGTATGATTCTCTGCTGTATCTTCCCCCGGATCTCCAAGCAGCCAGGGGTCTTATGTGCTCCTCTGTTGCTTTGACCGCCATCGGTTGCATTGTGGCCACCGTCGGCATGCGTTGCACCCGTCTGGTCGATTCCCGGCCCAAAGTAAAGCACATCGTTCTGGTGAGCGGAGGCTGTTTGTTTTTGGCTGGATGCTTGACCACTATTATTCCAGTGTCGTGGACTGCTCATGTGATCATACAAGACTTCTACAACCCTTTGCTTATCGATGCA[C/T]AGCGTAGAGAGCTTGGCGAGGCTTTATATGTCGGATGGGTCACTTCTGCTCTGCTTTTCATCGCCGGTGTGATTCTGCTTTGTCGACATGCACCAAGAACCCAAGCCAAAGAAGACATGGCTACTGTCTTGTATCGTGCCGGATCGGCTCCCTATAACTACTCTTATGCGCCCGGATATGGATACCAGCCTCCTTACGGATACCAGCCTGGGTATACCTATCAGCCGACGTATTCCCCAGTCCCGCCGACAGTCTACAGCCAGCCCAGATACTAAGAGACAGTAAATAAATGAAAGAACTTGAGAAGAATCTGGGTTGAAGAAAGCAGGACTGTTGATGAAGAATCATTGTCGATTATGTCTGACTGTATATATGAGCTGTATGATGATTTAAATGCATTTCTTTATTATAGACTGTTCATTATTTACATTTATACATGTGCTAGAATTTAAAAGCCACATGTGGGATATTTCCACACAGCATTTAATGTTGACATAGAG

Associated Phenotype:

Not determined