ZMP

mecom

Ensembl ID:

ENSDARG00000060808

ZFIN IDs:

ZDB-GENE-050208-123, ZDB-GENE-050208-123

Description:

Ecotropic viral integration site 1 [Source:UniProtKB/TrEMBL;Acc:A5HML2]

Human Orthologue:

MECOM

Human Description:

MDS1 and EVI1 complex locus [Source:HGNC Symbol;Acc:3498]

Mouse Orthologue:

Mecom

Mouse Description:

MDS1 and EVI1 complex locus Gene [Source:MGI Symbol;Acc:MGI:95457]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa24992	Essential Splice Site, Missense	Mutation detected in F1 DNA	Not yet available
sa42598	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa24992

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site, Missense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000086051	Missense	266	602	2	7
ENSDART00000128996	Essential Splice Site	432	1042	None	15

Genomic Location (Zv9):

Chromosome 15 (position 34665737)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	35539928
GRCz11	15	35397897

KASP Assay ID:

554-7421.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GGGTGCGAGTGCGGGAGAACGGAAAAGGACCAAAAAGGAAGTCCAGCGGG[T/C]TCAATGATGCCCAGAGTCCAACTCTTGTTAGCTCCAGTAGTAGTAGCAAC

Long Flanking Sequence:

GAATGAGCCATGGGAGTCCTGGTTTAGCAGACTATTTTGGGACAAACCGGCATCATAGTGGGCTGACGTTCCCAGCAGCCCCTCCGGCATTCCCATTCAGTTTTCCAGGACTTTTCCCATCAGGACTTTACCATCGGCCCCCTCTAATCCCATCCACATCGCCCATTAATGGCCCTCCGAGCACTGAACTACGAAAGAGTCCACTGCTGTCCTCACCCATTTCTGGCTCACATGAGCTCTTGAAGAGCTTACGCAAGGATTCATTCAACGGGGAAAGCGAGAATATGGAGCGTCAGAGAGAAGGATCCATCTCTAAGCCAAGGCATGGCGGGAAGATGAGCGACCAATCGGAGAGTAGCGATCTGGATGATGTCAGCACTCCCAGCGGGAGTGAGTTGGAGAGCACTTCAGGTTCAGAGCTGGACAGTGAAGTGGAAAGTGACCGGGAACGGGTGCGAGTGCGGGAGAACGGAAAAGGACCAAAAAGGAAGTCCAGCGGG[T/C]TCAATGATGCCCAGAGTCCAACTCTTGTTAGCTCCAGTAGTAGTAGCAACACTAATAATGTCAAAGACTTCCCTGCGCCAGGGCTCCTACCGCCATCTCTAGATGAGCAAACAGCCGTTTCTGGTGCTGTTAATGACTCGATTAAGGCTATTGCCTCCATTGCTGAGAAATATTTTGGTTCTACTGGACTTGCAGGCCTGCAAGATAAAAAAGTTGGGGCATTGCCCTACCCTTCCATGTTCCCACTGTCTTTTTTTCCAGCCTTTTCTCCATCCGTCTATCCATTCCCTGAAAGGGAGCAACTTAGACCTCCAGGCCACAAAGGGGAACCAGAAAGCCCTCCGGTTGAGAGTAAAAAGCCTCAGGGCAGAAATGCTGAATCACCTTTTGACCTCACCACAAAGCGGAAAGAAGAGCGACTTGCTGCCACCTGCGCCCCTGTAAAACCAGAAGCCTCACACGTACAATCAACCAACCAGGATCAGCCGCTGGACCTAAGT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa42598

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000086051	None	None	602	None	7
ENSDART00000128996	Nonsense	800	1042	11	15

Genomic Location (Zv9):

Chromosome 15 (position 34647300)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	35521491
GRCz11	15	35379460

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ACAAAGAGAAACCCTTCAAATGCCACCTGTGCGACCGCTGCTTCGGGCAA[C/T]AGACCAACCTGGATCGGCATCTCAAAAAACACGAGAATGGTAATTTAGCA

Long Flanking Sequence:

TGATCAGCCTTTAACTGCTATTTAATTTCGATTTTTTTTTTGTTCTGTCGCTTTCGGAGGAGAGAGAGTCGGAGAGATAACAGGTTCCTGGGAGACGCAGTTTAGCGCGTAACTCCACGGGTTGCAGGGAAGATATGATCACGTAATCATACAGGATAATTCTGCGTGAAGAGACTTGGCAACCGCATGAGCTTTTTGAGCGGAGGGAGGATGTGGAGTTTTGAGTGTTACTGAGTTGGCCAAAGATTAGAGACTCAGAGTTCATGACCACTCAATCATGTGTTTGAGACCCTGCGTGTGTGCGAGACGGATAAAGCAAGAGAGAGAGTTGTGAAATACAGTGTTTGGTTAATTAAAGTCGTATGCGTCTTTGTGTCCGCAGATGTAAGTATTGCGATCGCTCGTTCAGCATTTCGTCGAATCTTCAGCGCCACATCAGGAACATCCACAACAAAGAGAAACCCTTCAAATGCCACCTGTGCGACCGCTGCTTCGGGCAA[C/T]AGACCAACCTGGATCGGCATCTCAAAAAACACGAGAATGGTAATTTAGCAGGTAGACACACACATATGAATAAAAAGCCGACATTTTAGATCTTCTTTTATGAATGCGTATTTAATATGCGGAGTCTTATGTATAGATGATATTAATTGTTGTTTGTTGTGTAGGCACAGCAATGTCATCACCTCGTTCAGAGCTGGACAGCAGCAGTGCCATCTTGGAGGACAAGGAAGACTCGTATTTTAATGAAATACGAAATTTCATCAGTAATACGGCTCGAAATGCCACGTCTCCATCCCAGTCTGAGGAAGGGTAAATATAGTCTTCTTTTGCACTGATAAATGCAGTTCATATGCAAAGACCAACTTTTATTAGGTGTAACTGCTGACTTGCTGTCAAACAAGTGGTTTAATATTTTACATATCTTCACATCAGTCCAATTCATCATTTATTTCCTCCTATCAAATCTGATCATTTTAATTTAATACATTTTTTTATTTTAT

Associated Phenotype:

Not determined