ZMP
zgc:101015
Ensembl ID:
ZFIN ID:
Description:
Ras-related protein Rab-4B [Source:UniProtKB/Swiss-Prot;Acc:Q68EK7]
Human Orthologue:
RAB4B
Human Description:
RAB4B, member RAS oncogene family [Source:HGNC Symbol;Acc:9782]
Mouse Orthologue:
Rab4b
Mouse Description:
RAB4B, member RAS oncogene family Gene [Source:MGI Symbol;Acc:MGI:105071]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa30988 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa42493 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa35811 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa30988
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000008273 | Essential Splice Site | 6 | 213 | None | 8 |
| ENSDART00000008273 | Essential Splice Site | 6 | 213 | None | 8 |
The following transcripts of ENSDARG00000012177 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 15 (position 8991518)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 8880131 |
| GRCz11 | 15 | 8856202 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCCGGTCGATTGGTTTCATCGGTGGGACCGACATGTCAGAGACGTACGG[T/C]AATGACATTTTTTGTTGTGGTTAGCACTTACAGTTAGCTAGTGCTGGCGC
Long Flanking Sequence:
AAAAAGACAAATCTGCAACAAAATTACCATTCATAAATGTCAATCTACTAATAAGAAACCGAATTTTAAGGTACCGATGACTGAATTATGCTTATATATTAGACTTTTAGAGACTCTAAGAAAACCCTAAGCACTTTAAAACTTTGTGAATTTTACAATGTGTTTATTTGATTATTACATACGTACATTCTGAATATTTGTATTTGATTTATACTTACCACCTGGCATGTATATATATATTTTTGTACTGTTAAAAAGGCAAATTTGCGTCATGACATCACTCCTCTGTAGCGAGCACGTTGTGCACGCGCAGGTCTGTGCTGTGTAAAACAGGAAACGTCGAAAGGCGTTAGCAGCAGTTAATTATTAGCCTGTTGGCTACCACAGCTACACACAGAAACAAACCACAGCAAAGCCTTCATCTGAAGAAGCCAATAAAGACTATCGCCTGCCCGGTCGATTGGTTTCATCGGTGGGACCGACATGTCAGAGACGTACGG[T/C]AATGACATTTTTTGTTGTGGTTAGCACTTACAGTTAGCTAGTGCTGGCGCGTGCGTGAGAGTGAGCGCGCGTGCTGTATCAACATCACCAGCAGGCAGACGATTTCTGACTTCAGACCTCTAGTTTTTTCACAATTATAGATTAGTACGTGGCGTGTCAATCACAAGTGCTTAGCCATGCTACTGTCATTCTTGCTGGTCGAGACTGTCTGTAAATATCAGGTAAATATGTGTTTATTAGGTTAATGTCCACACTCTCAGATGGGCCTGTCAGATAAGCAGTTGGGTGTGTGGTGATGATGTCTAAAAAATTTGCCTACGTATTGACACAAGCTGATAAATCTATTCTGTAATTCCTGGTTATGCCATGATTACGATGTTTTAAGCCATCATATAAATGTTTAAAAAGCTCCTTCCGTCGTATTATTATTGCTTTAAGCGAATATGTTTTGGACACATCTCAATATTAAACAAATAATATAAATAATAACAATATGAGAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa42493
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000008273 | Essential Splice Site | 6 | 213 | None | 8 |
| ENSDART00000008273 | Essential Splice Site | 6 | 213 | None | 8 |
The following transcripts of ENSDARG00000012177 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 15 (position 8991518)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 8880131 |
| GRCz11 | 15 | 8856202 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCCGGTCGATTGGTTTCATCGGTGGGACCGACATGTCAGAGACGTACGG[T/C]AATGACATTTTTTGTTGTGGTTAGCACTTACAGTTAGCTAGTGCTGGCGC
Long Flanking Sequence:
AAAAAGACAAATCTGCAACAAAATTACCATTCATAAATGTCAATCTACTAATAAGAAACCGAATTTTAAGGTACCGATGACTGAATTATGCTTATATATTAGACTTTTAGAGACTCTAAGAAAACCCTAAGCACTTTAAAACTTTGTGAATTTTACAATGTGTTTATTTGATTATTACATACGTACATTCTGAATATTTGTATTTGATTTATACTTACCACCTGGCATGTATATATATATTTTTGTACTGTTAAAAAGGCAAATTTGCGTCATGACATCACTCCTCTGTAGCGAGCACGTTGTGCACGCGCAGGTCTGTGCTGTGTAAAACAGGAAACGTCGAAAGGCGTTAGCAGCAGTTAATTATTAGCCTGTTGGCTACCACAGCTACACACAGAAACAAACCACAGCAAAGCCTTCATCTGAAGAAGCCAATAAAGACTATCGCCTGCCCGGTCGATTGGTTTCATCGGTGGGACCGACATGTCAGAGACGTACGG[T/C]AATGACATTTTTTGTTGTGGTTAGCACTTACAGTTAGCTAGTGCTGGCGCGTGCGTGAGAGTGAGCGCGCGTGCTGTATCAACATCACCAGCAGGCAGACGATTTCTGACTTCAGACCTCTAGTTTTTTCACAATTATAGATTAGTACGTGGCGTGTCAATCACAAGTGCTTAGCCATGCTACTGTCATTCTTGCTGGTCGAGACTGTCTGTAAATATCAGGTAAATATGTGTTTATTAGGTTAATGTCCACACTCTCAGATGGGCCTGTCAGATAAGCAGTTGGGTGTGTGGTGATGATGTCTAAAAAATTTGCCTACGTATTGACACAAGCTGATAAATCTATTCTGTAATTCCTGGTTATGCCATGATTACGATGTTTTAAGCCATCATATAAATGTTTAAAAAGCTCCTTCCGTCGTATTATTATTGCTTTAAGCGAATATGTTTTGGACACATCTCAATATTAAACAAATAATATAAATAATAACAATATGAGAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa35811
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000008273 | Essential Splice Site | 71 | 213 | 3 | 8 |
The following transcripts of ENSDARG00000012177 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 15 (position 8969886)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 8858499 |
| GRCz11 | 15 | 8834570 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAACAGTCAAACTGCAGATCTGGGACACGGCTGGACAGGAGCGCTTTAGG[T/C]ACTCGCCTGTGATTGGTTGATTTGGAACTGCTCACTGTTAAAGGCGGACT
Long Flanking Sequence:
CAATATTCAATATTTATATAAAGAGTATTAATTATTATTGTTTATAGAATTTATATTATTATATTCCATTTAGTTTTTTACTTCCTGCTCTCCATCTGAATTTTGTGCATCACCAGAATTTACGAGATTGCAAGCAACCTATTTCAGCTTGGATTGTGTTTTTGAACACGTAACAATGTAATCCAGAGGTTTCAAAGAGATTGTTATTGAAAGGCAGGGCCACAAAATCTATATTTGACCTGACAGCAAACCAACAACCCGTAAATAAAACGGGAAAACGTTGGATCTTACAGAACATTTACCTTGAAGTGGGGAGAGAGTGGCCTTAAATCAATTATTTCAGCAATCCATTCTCCACCTCTTACCACTCATGTTGTGTCACAGTCAAACAGGACTCCAATCACACCATCGGCGTTGAGTTCGGCTCCAGGGTTGTCAATGTTGGTGGCAAAACAGTCAAACTGCAGATCTGGGACACGGCTGGACAGGAGCGCTTTAGG[T/C]ACTCGCCTGTGATTGGTTGATTTGGAACTGCTCACTGTTAAAGGCGGACTGTGATTGGCGGAGGTTATTCACTGCTTGTGTGTGTTTCAGGTCAGTGACCCGCAGTTACTATCGTGGAGCAGCAGGAGCTCTTCTCGTGTATGACATCACAAGGTAAGGCTGACACCGCGGGTTACCCCACTACAAGCTGTGGAATGGTGAAAAAAATTATAATTAATTTTTTTTTTCTTATAGGACATAAACCAAAACTTGAACAGAAAGAACAGTATCCCCTATGTAAAATTTCAAAAACACATTTCATTTTTTTGGTATTATTATTAGATTTTAAATGGATACATATTAGTTTAGTTATCTAGTTCAGGGATTCCCAAACTTTTTTATTCCAGGACCCACCTTGGCAAGTTATTCAATCTCAAGACCCACCATAATATTTTAATATGGAAAAATGGGTTAAAAAATGTATCCATTCAAAGCAGTCAAAAATAAATGGTGTGTGGCTT
Associated Phenotype:
Not determined