Busch Lab

ZMP

ENSDARG00000015247

Ensembl ID:
ENSDARG00000015247
Mouse Orthologue:
F8
Mouse Description:
coagulation factor VIII Gene [Source:MGI Symbol;Acc:MGI:88383]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa15845 Essential Splice Site Available for shipment Available now
sa22404 Missense Available for shipment Available now
sa42320 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa5870 Nonsense Mutation detected in F1 DNA Not yet available
sa7229 Nonsense Mutation detected in F1 DNA Not yet available
sa19072 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa15845
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014159 Essential Splice Site 338 2147 8 37
Genomic Location (Zv9):
Chromosome 14 (position 1012866)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 996210
GRCz11 14 1014474
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CATMAACTCAGGCTGATGGAAACCYAATGCATGYCTCTGTGTTGTTCTCC[A/G]GCKGGTATGAATGCGTTCTTCACTGTTGAAAACTGTCCTGAACCYGCACC
Long Flanking Sequence:
CGCCATTGTGCTGCCCTGACATCCAGATATGATGGTTAAAATGCACATTCCTTTTTATTTCTCATGAGTAATTCTGTGTTTGTGGTTCGCTCAGGTCTGAGTGTGTGTGAGAAGAGTCCGCAGGTCTCCTGGCACCTCATAGGTCTGGGCTCCAGTCCTGAGATCCACAGCATCCAGTTTGAAGGACACACGCTGAAGGTGTTCGACCACAAGCGGGTGACGGTGGAGATGACACCCATGACCTTCACCACAGCCCTCATGAAGCCCTCGGCCACGGGGAGGTTTCTGATCTCCTGCAGGATCCACTCGCATCAGACAGGTCAGACTCGCTAAACTTACTCGCACTATACTGTCCTAATGAAAGCATTCAAAATCAAGGCATGATCATATTTTATAATATATATATTTTATTTAGTTTATTGTTGCTATCATGTGATACTTCAAGATGAGCATCAACTCAGGCTGATGGAAACCCAATGCATGTCTCTGTGTTGTTCTCC[A/G]GCTGGTATGAATGCGTTCTTCACTGTTGAAAACTGTCCTGAACCCGCACCGCTTCCCCTCCCGGACAAGAGAAACGTCAAGCACACTAATGACGATGAGGAGGAGGATGATGAAGACAACATGTTCTCTGTGGTGTTCAAACAAGGAGGTCCAATATCTGTGCTTCGCTCCAGCGCGAAGGGCCGACCCAAAGTGTGGCTCCATTACATCTCTGCAGAGGAGACGGACTGGGATTATACCGCTCAGAGCGGAGATCGGTACGCCTCACAACTCTGACATTACTTTCCTCTTTGCCATGATGACAGCAATATTGGACTAGATATTAGTAGTCAGCTTAAAGTGACATTTAAAGGCTTAACTAGGGTAAAGTAGTAAGGCAAGTTATTGTATAACAGTGGTTTGTTCTGGAGACAATGTAATATTGCTTAAGGGGGCTGATAATATTGACCTTAACATGGCTTTAAAACAATTAAAACTGCTTTTATTCTAGCCGAAATAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22404
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014159 Missense 508 2147 10 37
Genomic Location (Zv9):
Chromosome 14 (position 1015699)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 999043
GRCz11 14 1017307
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTATCCAAACGGCCTGACCAGCGTTCAGCCTCTGAAGACAACAAACAAAG[G/A]TATGAACCACGGTGGCTCAGTGGTGAGCACTGAAGAAGCAAGAAGGTCGC
Long Flanking Sequence:
AGCTCCATATCACTCCACTGAAGGATTAGAGTTCACTCACAGCTACACCAGTCAGAAAGCACATCAGAACACGACAGAAGGCTTTGGAGGAGATGTGAAAGTAACTAGTGCAGTTTGAGGAGGGAAAACACCGGACTAATACAACATCTGAGCAGTGGATTTAGCTGTGGTGACCATAATATAATCGGAATAATCATTAGAAATTGCAAACTGAAGGTCACCACATTAGCTGTGCATTATTTTCTAATAATTCACTGCCCTGTAGTTAATTACTCGTTGAAATTAGAGCAAATCTTACTTTGATGAATTGTTAATTATGAAAAAATAAGATGTATGATAAATGTAGAGTGAGTTTGATGCTAACTTTAAAGTCTGATGTCATTAACTTGTCTCTTTTGTTTCTCTCTATCAGATTGTGTTTAAAAATATGGCCAGTCGTCCATTCAACATTTATCCAAACGGCCTGACCAGCGTTCAGCCTCTGAAGACAACAAACAAAG[G/A]TATGAACCACGGTGGCTCAGTGGTGAGCACTGAAGAAGCAAGAAGGTCGCTGGTTCGAGCCTCAGCTGGGTCAGTTGGTGTTTCTGTGTGGAGTTTGCATGTTCTCCCCGTGTTAGCGTGGGTTTCCTCCGGGTGCTCCCCCACAGTCCAAACACATGCGCCATAGGGGAATTGATGAACTAAATTGGCCGTAGTGTGTGTGAATGAGTGTGTATGGGTGTTTCCCAGTGCTGGGTTGCAGCTGGTAGAGCATCCGCTGTGTAAAACATATGCTAGAATAGTTGGTGGTTCATTCCACTATGGCGACCTCTGAAATAGAAACTAAGCTGAAGGAGATTGACTGAATGAATGAATGAACCAGTGGTTTTCCTGTTTCTGACAGAAGGGTAACTCATTCATACATTTTCTTGTCAGCTTAGTCCCTTTATTAACCCGGGGTCGCCACAGCGGAATGAACCGCCAACTTATCCAGCAAGTTTTTGAGCAGCAGATGCCCTTCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42320
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014159 Essential Splice Site 509 2147 10 37
Genomic Location (Zv9):
Chromosome 14 (position 1015705)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 999049
GRCz11 14 1017313
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAACGGCCTGACCAGCGTTCAGCCTCTGAAGACAACAAACAAAGGTATGA[A/C]CCACGGTGGCTCAGTGGTGAGCACTGAAGAAGCAAGAAGGTCGCTGGTTC
Long Flanking Sequence:
ATATCACTCCACTGAAGGATTAGAGTTCACTCACAGCTACACCAGTCAGAAAGCACATCAGAACACGACAGAAGGCTTTGGAGGAGATGTGAAAGTAACTAGTGCAGTTTGAGGAGGGAAAACACCGGACTAATACAACATCTGAGCAGTGGATTTAGCTGTGGTGACCATAATATAATCGGAATAATCATTAGAAATTGCAAACTGAAGGTCACCACATTAGCTGTGCATTATTTTCTAATAATTCACTGCCCTGTAGTTAATTACTCGTTGAAATTAGAGCAAATCTTACTTTGATGAATTGTTAATTATGAAAAAATAAGATGTATGATAAATGTAGAGTGAGTTTGATGCTAACTTTAAAGTCTGATGTCATTAACTTGTCTCTTTTGTTTCTCTCTATCAGATTGTGTTTAAAAATATGGCCAGTCGTCCATTCAACATTTATCCAAACGGCCTGACCAGCGTTCAGCCTCTGAAGACAACAAACAAAGGTATGA[A/C]CCACGGTGGCTCAGTGGTGAGCACTGAAGAAGCAAGAAGGTCGCTGGTTCGAGCCTCAGCTGGGTCAGTTGGTGTTTCTGTGTGGAGTTTGCATGTTCTCCCCGTGTTAGCGTGGGTTTCCTCCGGGTGCTCCCCCACAGTCCAAACACATGCGCCATAGGGGAATTGATGAACTAAATTGGCCGTAGTGTGTGTGAATGAGTGTGTATGGGTGTTTCCCAGTGCTGGGTTGCAGCTGGTAGAGCATCCGCTGTGTAAAACATATGCTAGAATAGTTGGTGGTTCATTCCACTATGGCGACCTCTGAAATAGAAACTAAGCTGAAGGAGATTGACTGAATGAATGAATGAACCAGTGGTTTTCCTGTTTCTGACAGAAGGGTAACTCATTCATACATTTTCTTGTCAGCTTAGTCCCTTTATTAACCCGGGGTCGCCACAGCGGAATGAACCGCCAACTTATCCAGCAAGTTTTTGAGCAGCAGATGCCCTTCCAGCCGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa5870
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014159 Nonsense 929 2147 17 37
ENSDART00000014159 Nonsense 929 2147 17 37
Genomic Location (Zv9):
Chromosome 14 (position 1019096)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 1002440
KASP Assay ID:
554-3730.1 (used for ordering genotyping assays)
KASP Sequence:
AGCAGACRGCGCTCTAGGCTAGTTATGAACAGTACAAGGCACAGTAGATG[G/A]CGCTCTAGGCTAGTTTTTAACAGCAGACAGTGCTCTAGGYTAGTTATTAA
Long Flanking Sequence:
GATACTATTTAACAGCAGATGGTGCTTTAGGCTTGTTATGAACAGGACATGACACAGTAGATGGCGCTCTAGGCTAGTTTGTTACAGCAGAAAGTGCTCTAGGCTAGTTTGTAACCGCAGGCAGTGCTCTAGGCTAGTTATTAACAGTAGAAGGTACTCTAGCCTAGTTTTTAACAGTAGATGGCACAGTAGATGACGCTCTAGGGTAGTTTTCAATAGTAGATGGTGCTCCAGGCTAGTTTTTAACAGCAGTCGGTGCTTTAGGCTAGTTTTTACAGTAGATGGAGCAGTAGATGGTGCTCTAGGGTAGTTTTTAATAATAGATGGTGCTCTAGGCTAGTTTTTTACAGCAGACAGTGCTCTAGGCTAGTTTTTTACAGCAGACGGTGCTCTAGGCTAGTTATTAACAATAGACGGCACAATAGATGGTACTCAATGATACTTTTTAACAGCAGACAGCGCTCTAGGCTAGTTATGAACAGTACAAGGCACAGTAGATG[G/A]CGCTCTAGGCTAGTTTTTAACAGCAGACAGTGCTCTAGGCTAGTTATTAACAGTAGACGGCATAATAGATGACGCTCTATGATACTTTTTAACAGTAGATGGCACTCTAGACTATTTTTTTATAGTAGATGATGATCTAACAGCACCGTCTGCTGTTAAATCCTAGCCTAGAGCTGCAGTTAAAAAACTAACCATGAGTGCCAAGAAAACTAGCCTAGAGTGCCATCTACTGTTAAAAACTAGCATATAATTGTAATATAATATATATCCAGCTGGTTATTTTATGCAAAATAAAAGATAATGTAACTTGTAATTATTTGCAATCTATCAGGTCGTTTCATACACCATTTTTACATTTAGGATTGAAACTATACGCATGCATAGATGGTAGTAAATGCTGCTGATGTTGTTACAGGTGACGTCAGATAAAGAGAAGAAGCTGTTGTTTACGGTGTTTGATGAAAACAGAAGCTGGTACTTCGAGGAAAACATCAAGAGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7229
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014159 Nonsense 929 2147 17 37
ENSDART00000014159 Nonsense 929 2147 17 37
Genomic Location (Zv9):
Chromosome 14 (position 1019096)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 1002440
KASP Assay ID:
554-3730.1 (used for ordering genotyping assays)
KASP Sequence:
AGCAGACRGCGCTCTAGGCTAGTTATGAACAGTACAAGGCACAGTAGATG[G/A]CGCTCTAKGCTAGTTTTTAACAGCAGACAGTGCTCTAGGYTAGTTATTAA
Long Flanking Sequence:
GATACTATTTAACAGCAGATGGTGCTTTAGGCTTGTTATGAACAGGACATGACACAGTAGATGGCGCTCTAGGCTAGTTTGTTACAGCAGAAAGTGCTCTAGGCTAGTTTGTAACCGCAGGCAGTGCTCTAGGCTAGTTATTAACAGTAGAAGGTACTCTAGCCTAGTTTTTAACAGTAGATGGCACAGTAGATGACGCTCTAGGGTAGTTTTCAATAGTAGATGGTGCTCCAGGCTAGTTTTTAACAGCAGTCGGTGCTTTAGGCTAGTTTTTACAGTAGATGGAGCAGTAGATGGTGCTCTAGGGTAGTTTTTAATAATAGATGGTGCTCTAGGCTAGTTTTTTACAGCAGACAGTGCTCTAGGCTAGTTTTTTACAGCAGACGGTGCTCTAGGCTAGTTATTAACAATAGACGGCACAATAGATGGTACTCAATGATACTTTTTAACAGCAGACAGCGCTCTAGGCTAGTTATGAACAGTACAAGGCACAGTAGATG[G/A]CGCTCTAGGCTAGTTTTTAACAGCAGACAGTGCTCTAGGCTAGTTATTAACAGTAGACGGCATAATAGATGACGCTCTATGATACTTTTTAACAGTAGATGGCACTCTAGACTATTTTTTTATAGTAGATGATGATCTAACAGCACCGTCTGCTGTTAAATCCTAGCCTAGAGCTGCAGTTAAAAAACTAACCATGAGTGCCAAGAAAACTAGCCTAGAGTGCCATCTACTGTTAAAAACTAGCATATAATTGTAATATAATATATATCCAGCTGGTTATTTTATGCAAAATAAAAGATAATGTAACTTGTAATTATTTGCAATCTATCAGGTCGTTTCATACACCATTTTTACATTTAGGATTGAAACTATACGCATGCATAGATGGTAGTAAATGCTGCTGATGTTGTTACAGGTGACGTCAGATAAAGAGAAGAAGCTGTTGTTTACGGTGTTTGATGAAAACAGAAGCTGGTACTTCGAGGAAAACATCAAGAGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19072
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014159 Nonsense 1836 2147 31 37
Genomic Location (Zv9):
Chromosome 14 (position 1031672)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 1015016
GRCz11 14 1033280
KASP Assay ID:
2260-7111.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACTGTATAGTTGGAGGCCTAAACTGATTTTTGTTTTAACAGAATGCAAT[C/T]AGCCCATAGGAATGCAATCAAGATGGATCACCAACAAACAAATAACAGCG
Long Flanking Sequence:
AATAGATAAATAACAATACTGAAGCACTGTGATGACGAGCTGACGGAGACCTGATGCCTTTTCCAATCAGCAGAACAACATTTCAGATCTGCAACAATGGAAAGCTGAAAAACATGGAGAGCTGCAAGCCAACATTAATGACACAAAAACCCTCAAATGCACATCTATATCTGTGAACAACTACATCACAGCATGCAGACTGATGAGTTTATTCACTAATGTGTTTCTATCATAGTTTATGCACACTATCGGATGTTTATCTTGCTCAATTTATATGCTTACCTTTTTTATAGGCATTTTCAAAATTCCTGAGCATCTTCACATTTCCATTCAGAGTTATTTTATGTGATATTTTAAACTGTGCATAAAAATAGGTGGATGGAAACATAGCTAATAGGAGATTGTCATGGATGTTTCTTTGCATTGTGTTTGTGCAGTCATGTCTTCTATCACTGTATAGTTGGAGGCCTAAACTGATTTTTGTTTTAACAGAATGCAAT[C/T]AGCCCATAGGAATGCAATCAAGATGGATCACCAACAAACAAATAACAGCGTCTGATTACTACGGTAAGAAAAAACAACACAAAATGATATTACTAAAAGACACAGGACTTAAAGAGGCCACATGAAGCTTCATTATGCACAAGTATTCTATAGCAGGAATACATTTAATACACTTCAATAAATCAAGCAAGTTGCAGTACAAACCGCAAGTCACATTACATGATTTGACTGATTTCCACCTCAAATTGGGGTTTGTGAAGGATTTAATTCAGACGGCTGGAAACGGCACATGATACATTGCCATAACTGCTATTCGCATTCATTCATTTTCTTTTCGGCTTAGTCCGTTTTTTAATGAGAAGTCACCACAGTGGAATGAACCGCTATAAATGCTATTGTATTATTGCTAATTATTGTTTTCTTCATTATTGTTGGCAGCCTGAAACTGACATTTAATTTAGATGAATTGCACAGCCTTAGTAGAAACACTGTTTTAAGCA
Associated Phenotype:
Not determined