ZMP

Ensembl ID:

ZFIN IDs:

ZDB-GENE-090313-125, ZDB-GENE-990603-4, ZDB-GENE-990603-4

Description:

Novel protein similar to H.sapiens MAP3K4, mitogen-activated protein kinase kinase kinase 4 (MAP3K4)

Human Orthologue:

MAP3K4

Human Description:

mitogen-activated protein kinase kinase kinase 4 [Source:HGNC Symbol;Acc:6856]

Mouse Orthologue:

Map3k4

Mouse Description:

mitogen-activated protein kinase kinase kinase 4 Gene [Source:MGI Symbol;Acc:MGI:1346875]

Allele Name:

sa42251

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000075333	Essential Splice Site	32	1488	1	30
ENSDART00000137256	Essential Splice Site	66	770	2	8

The following transcripts of ENSDARG00000053303 do not overlap with this mutation:

• ENSDART00000140322

Genomic Location (Zv9):

Chromosome 13 (position 36228268)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	35700834
GRCz11	13	35826666

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

Flanking Sequence:

Long Flanking Sequence:

Associated Phenotype:

Allele Name:

sa42250

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000075333	Nonsense	53	1488	3	30
ENSDART00000137256	Nonsense	87	770	3	8

The following transcripts of ENSDARG00000053303 do not overlap with this mutation:

• ENSDART00000140322

Genomic Location (Zv9):

Chromosome 13 (position 36226953)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	35699519
GRCz11	13	35825351

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

Flanking Sequence:

Long Flanking Sequence:

Associated Phenotype:

Allele Name:

sa1374

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000075333	Nonsense	196	1488	3	30
ENSDART00000137256	Nonsense	230	770	3	8

The following transcripts of ENSDARG00000053303 do not overlap with this mutation:

• ENSDART00000140322

Genomic Location (Zv9):

Chromosome 13 (position 36226524)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	35699090
GRCz11	13	35824922

KASP Assay ID:

554-1286.1 (used for ordering genotyping assays)

KASP Sequence:

Long Flanking Sequence:

Associated Phenotype:

Stage	Entity	Quality	Tag
Larval:Day 5 ZFS:0000037	whole organism ZFA:0001094	quality PATO:0000001	normal PATO:0000461

Allele Name:

sa11281

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000075333	Nonsense	599	1488	7	30
ENSDART00000137256	Nonsense	659	770	6	8

The following transcripts of ENSDARG00000053303 do not overlap with this mutation:

• ENSDART00000140322

Genomic Location (Zv9):

Chromosome 13 (position 36219921)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	35692487
GRCz11	13	35818319

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

Long Flanking Sequence:

Associated Phenotype:

Allele Name:

sa22347

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000075333	Nonsense	1224	1488	23	30
ENSDART00000137256	None	None	770	None	8

The following transcripts of ENSDARG00000053303 do not overlap with this mutation:

• ENSDART00000140322

Genomic Location (Zv9):

Chromosome 13 (position 36202868)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	35675544
GRCz11	13	35801376

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

Flanking Sequence:

Long Flanking Sequence:

Associated Phenotype: