ZMP

si:ch211-51a6.2

Ensembl ID:

ENSDARG00000030967

ZFIN ID:

ZDB-GENE-090313-118

Description:

Novel protein similar to vertebrate protease, serine, 12 (Neurotrypsin, motopsin) (PRSS12) [Source:U

Human Orthologue:

PRSS12

Human Description:

protease, serine, 12 (neurotrypsin, motopsin) [Source:HGNC Symbol;Acc:9477]

Mouse Orthologue:

Prss12

Mouse Description:

protease, serine, 12 neurotrypsin (motopsin) Gene [Source:MGI Symbol;Acc:MGI:1100881]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa5858	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa42181	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa5858

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000021556	Essential Splice Site	118	832	3	14
ENSDART00000140307	None	None	554	None	8

Genomic Location (Zv9):

Chromosome 13 (position 21932350)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	21661688
GRCz11	13	21792138

KASP Assay ID:

554-3952.1 (used for ordering genotyping assays)

KASP Sequence:

AGACAGAAGTCTGGAGCCRTCGGGTGGGCTTACTGTGACTGCCACCAGGG[T/C]GAGCTCTACTCAATGCCTTCTCTCATGCAGTCATATTTATGGTGGTTATG

Long Flanking Sequence:

TGGACTACATCCAGAAGAGGCACTCTAGGGGTTTCACTGATACAGAAACCACTACAAAAACTATATATAATAATAATAAGACCACCTTCAGCCTGCATCCCTGCCGCTTTAAAAAAAAAAAGGTCTAGGTCATGCTTCTTTTTTATCCCAAAATCCTTTATATTGCACTGCATTGACTTGTCCTTTTATGCTCTGTGGAGGTGGTTTTTTCAAAGAAATTGAATGCTGAATTGAACTGAAGATGTGTTTCCCATAGGGCCTCTGTCCTGCTCTGAGGGCTTCACTGAGCTGGGTTATTACAACGGATCTGTGTCTCAGACCGACACTGGCTTTTCCTGTCTGAAATGGACTGAATTTCCAGACTACATGCTTCAGTACCCGAAGCGTGGGCTGGGGGACCACAACCACTGCAGAAACCCTGACCGTGAATCCAACCCCTGGTGCTTCTTCAGACAGAAGTCTGGAGCCGTCGGGTGGGCTTACTGTGACTGCCACCAGGG[T/C]GAGCTCTACTCAATGCCTTCTCTCATGCAGTCATATTTATGGTGGTTATGGTTTTGCAGTATGAGTTTTATATTCACAGATCAAGCAGAAATTAAACTTTACTCACCATTAAGTGGTTCCAACCCTTTAGGAATTTATTTTTCTGTTGAACACACACACAAAAATTATTTGGACATTAATAAAGGCCATTGAAAACCAGTGTGACCACAACATCTACTTTGGAAGGCAGTGGCTACCAGTTCTAAGCATTCTTCGAAATATCTTCTTTTGTGTTGAAGAGTAGAAAGTAGCTAAAACGGGTTTGAAACTATGACAGAATTTCCATATTTATGAAAAATATTCTTGTTGTGTCTAAATGATACAAAGCAACCAAAACGCATACCTGTATACCATTTTCAGAAGTAACGCTTGAAAAAGATGAACAGATGCAAAAAAATATGTACAAATGTTGTTTCTTCAAAATATTGTGCTAGCCAGTTATCTTTATTTAGTCTAGCAGG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa42181

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000021556	Nonsense	257	832	6	14
ENSDART00000140307	None	None	554	None	8

Genomic Location (Zv9):

Chromosome 13 (position 21941418)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	21670756
GRCz11	13	21801206

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GCCGTGTGGAGGTGTATTATAATGGACGGTGGGGGACCATCTGTGATGAC[G/T]AGTGGGATGATATTGATGCTGAAGTGGTTTGCAGACAGTTGGGATTGGGG

Long Flanking Sequence:

AATGAAGACAGAATTCATGCGAGACAGAAGCAGGGTCGTAAACAGTGTGCCTGTTGTAATGGGACAGTTTGCTAGAACAGGGTCAGGTATATTTAGAGAGAGCTGTGAATTATTCACACAGAAACATTAGGAAGGAGAAAGCAATCCGAGAGCTTTATGGCTTTGCCAACAGTCCTTACACATGTCCTTTTCCTTTACCACACATACATACATGCTTTAAAGCATTAAACCATAAGTGTGACTGAGATCTATAGTCTATTAAAGGGATTCCTTGCTGAAGCAGAGCAGAGTTTCAGACTTTTGCCATTAAGGTGAAAATGAATGAAATGTTGCACTGTAAACTTTGTCGTAATCATTTTCCTCTACATTGACTGAATGAATTGATTTGACTATTTTGTTTAGGAAATGGTGCCCCCCTGAGGCTCGTCGGGGGTCTTGAGGATTTCGAGGGCCGTGTGGAGGTGTATTATAATGGACGGTGGGGGACCATCTGTGATGAC[G/T]AGTGGGATGATATTGATGCTGAAGTGGTTTGCAGACAGTTGGGATTGGGGTAAGAAATCTGTAATCTGTGTCTTAAAGCAGGGGCTTGGAAACGTTTGTATGCCAGCAACCCACAAATAGTATTTTAACCTGTTCAGATTTTTATATTTAAATAATAATAATGTGTTTAATAATATAGCAGCAATATAATATATATTAATTGTAATGTCACTGTAATAAATTAAATAATTTATAAATATTACCTGGAAAATATGTATTTTCTATTAACCCTAGCATTTTAAATACCCTATTCTGTTAACATATTGAAATAAAAATAAAAAACACTTCAAAAACTATTCATACTGAGACAAAAACAGGTCTGGAACCAGGAAGAATTTAATTGTAAATTAAATTATATTGATTTATTTTTAAATACATTTTCTTAGGTTAATAAATTATAATATAAAAAAATAAAACTTTAATAGGCTACAAAACAAATATTTATAAATTTGATGTATAAA

Associated Phenotype:

Not determined