ZMP

nbr1

Ensembl ID:

ENSDARG00000077297

ZFIN ID:

ZDB-GENE-030131-9112

Human Orthologue:

NBR1

Human Description:

neighbor of BRCA1 gene 1 [Source:HGNC Symbol;Acc:6746]

Mouse Orthologue:

Nbr1

Mouse Description:

neighbor of Brca1 gene 1 Gene [Source:MGI Symbol;Acc:MGI:108498]

Alleles

There are 5 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa11901	Essential Splice Site	Available for shipment	Available now
sa22111	Essential Splice Site, Missense	Available for shipment	Available now

Mutation Details

Allele Name:

sa11901

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
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Mutation:

A > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000114556	None	274	1014	9	23
ENSDART00000133048	Essential Splice Site	268	989	None	21

The following transcripts of ENSDARG00000077297 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 12 (position 28790001)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	12	27127610
GRCz11	12	27218970

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

ATTGTATATRTWTGTTAAGGGAATTGAATTCATTTTTCTGTGTTGTTTTC[A/C]GGTTTCTGAGGCGGGGTGACAGGACGGTGAGAAAGGCGGAGAGGCAGCGT

Long Flanking Sequence:

GAGGAGCAGATTCACATTTACATTTAGAGAAGATGGAGGGGTAGAATTTATTAAGCTTAACCCTACAATAATGAATCTGGTGTACTATTTTATATTAAATTAGTTGGTGTCTTGAGTTAATAGAACAAGTGTTTATGGTATTAGTAATTTAAAATTTATTTAAGATTACAATTCAGAAGTACTCTTCCAATCTCACACTATTTGAGAAAATGAATGACCGTTCAATATGAACTCTTCCCTCCTCCTATGTGCAGTGTTTGTCCATCTTGCATCTTATGCGAGCCATGCAGTCATAAACACGATCCCAGCCACAACCTAAAGAGAACAAGGACTCCTCTGTCTGTCCCTGAACGTGGAGTTACCCCTGAACCCAGGTAGGCCAAAATAAACACTTGGTGCTCAAGATGTTGTGAATTTTCTGCTTGACCTAACGTGTTGTTTAGAGCGATGATTGTATATATATGTTAAGGGAATTGAATTCATTTTTCTGTGTTGTTTTC[A/C]GGTTTCTGAGGCGGGGTGACAGGACGGTGAGAAAGGCGGAGAGGCAGCGTCTAAAAGCAGAGCGGAGGCAGCTGAAGGCTGAGGTGAAGGAGATCAAGAAGAAGCTGAGGCTGGAGAAGAGAGGTCTGCTGTGGAGTGGAGCCTCCAACGGGACCAGCACCTCAGGCCTTGCCCCCGCTCCCGCCCCGTCTCTAGGTGCAGGACCAGCCCCAGCTCCGGCCCTGTGCCCAGACCCTCAAACTTCCAGTCCAGAGTAAGGGCCACACTGAGAGGGGTCAGGGCTGGGTGACCTCCCTACCCAGCCCAGAACAAACATTATCAAGATTTATCACATTGTCTGTTATAGTTGAGTTATCGCTGGCAAATGGATGGAACTACCTCAAAATAGCACCCGCTGCCTTTATGTATTACGTCCTTTTTTGTACTTTTTTGATATGAACTTCAAGGAAAAGACAGACGCTGAAACAAAGCTGTTCTGATGATCCTCTGTGCACTCAAAC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa22111

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

G > A

Consequence:

Essential Splice Site, Missense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000114556	Missense	699	1014	17	23
ENSDART00000133048	Essential Splice Site	692	989	16	21

The following transcripts of ENSDARG00000077297 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 12 (position 28792643)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	12	27130252
GRCz11	12	27221612

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TCCAGTTCCTGTGTCAAAGCCAATCATAACAGATGAACCTGTCTTTCCAG[G/A]TCTGCATGCCTTTTTTTTTTCTTGGTCACTGTTACTTAGGGTGCTTTTAC

Long Flanking Sequence:

GATTTTTAGATCTGTTAAAGGCTTTTGTGAATGAATGTCTTCCTGAACTGATTATGAACGTGTTACTAGTGACCTTTTATGTACTGACACGACTTATTCTCTGTTAGTCCTGCAGCCTCAGAGACAAAACGAGCTTCTGGATGTTCCAGGCAATGAGGAAGGAGACGAAGACATCAGTGGCACTCAGTTTGTGTGTGAGACTGTGATTCGCTCTCTGACTCTTGAGGAGGAACCAGAACGCAAACCTCAACGCAGAGCACGGCCCAGCCTGAGGAGGCATGATGGTGAGCTTCTGCTGGAATTCTGCTCACAAAAAAACAGATATTTGACTGGCCTTATTTTGTTTTTGTTCATTTTGCCTTCCTATTTTGCAGTTCCAGATCCTGTTCGCTTAAAGGAGAGATCAGTGCCGGTGAAGAATGACAGACCAGTCATAAACAGGCCTGAGGCTCCAGTTCCTGTGTCAAAGCCAATCATAACAGATGAACCTGTCTTTCCAG[G/A]TCTGCATGCCTTTTTTTTTTCTTGGTCACTGTTACTTAGGGTGCTTTTACACTTGGTTTAATTGCCTGGACCATACCAAAGTTCGATTGTCCTCCCCGGCCACCTTCTCGGTTGGTTTGTGTTCACACTTTCTTTTTTCCTTCTGAACCCCGTTACGCTTGCTTCATCAAGCTGCTGTGGTGTGTACAGCCTTTGGTTTTGGACATACAGAAAAGCAACTCGCGTCCATCTGTCGCAATATTATTATAAAAGTTCAGAACATAACGCAATGTTTTTGGAGGAGACAAGCAGACATTATCACTATGCTTGCCCTGGCTTAGTCCTGCTTGTCACCAAGGTACAGTACGTGATACACACACATACACACACACGAATGAACGTTATGAAATGCTGTTGATGGATCCATTATTTGGTACGATTGCATTCATATCAGAAGTGAAGCGGACCAGGACCGTACCCCAGACCACCTCTTTCAGCTGGACTCTGGTATATTTTGTGAG

Associated Phenotype:

Not determined